Antitumor mechanism of HG251, a novel anthracene derivative, in K562/DOX leukemia cells

Chinese Pharmacological Bulletin

Volumn 24, Issue 10, 2008, Pages 1340-1343

  Zhang, Zhong Quan ^a   Xu, Mei ^a   Xie, Song Qiang ^a   Hu, Guo Qiang ^a   Ji, Bian Sheng ^a  

^a HENAN UNIVERSITY   (China)

Author keywords

Anthracene derivative; Apoptosis; Caspase; Mitochondrial membrane potential; Multidrug resistance

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTHRACEN 9 YLMETHYLENE (2 METHOXYETHOXYMETHYLSULFANYL) 5 PYRIDIN 3 YL [1,2,4]TRIAZOL 4 AMINE; ANTHRACENE DERIVATIVE; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; DEATH RECEPTOR; GLYCOPROTEIN P; HG 251; PROTEIN BCL XL; PROTEIN P53; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL ASSAY; CELL CYCLE; CELL PROLIFERATION; CELL STRAIN K 562; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INHIBITION KINETICS; LEUKEMIA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING;

EID: 58149202368     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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