-
1
-
-
0033992544
-
Inhibition of glutathione depletion by retinoic acid and tocopherol protects cultured neurons from staurosporine- induced oxidative stress and apoptosis
-
Ahlemeyer B, Krieglstein J. 2000. Inhibition of glutathione depletion by retinoic acid and tocopherol protects cultured neurons from staurosporine- induced oxidative stress and apoptosis. Neurochem Int 36:1-5.
-
(2000)
Neurochem Int
, vol.36
, pp. 1-5
-
-
Ahlemeyer, B.1
Krieglstein, J.2
-
2
-
-
12644298684
-
Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: Role ofnitric oxide
-
Casini A, Ceni E, Salzano R, Biondi P, Parola M, Galli A, Foschi M, Caligiuri A, Pinzani M, Surrenti C. 1997. Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: Role ofnitric oxide. Hepatology 25:361-367.
-
(1997)
Hepatology
, vol.25
, pp. 361-367
-
-
Casini, A.1
Ceni, E.2
Salzano, R.3
Biondi, P.4
Parola, M.5
Galli, A.6
Foschi, M.7
Caligiuri, A.8
Pinzani, M.9
Surrenti, C.10
-
3
-
-
0038002238
-
Prevention of cultured stellate cell transformation and endothelin-B receptor up-regulation by retinoic acid
-
Chi X, Anselmi A, Watkins S, Gandhi CR. 2003. Prevention of cultured stellate cell transformation and endothelin-B receptor up-regulation by retinoic acid. Br J Pharmacol 139:765-774.
-
(2003)
Br J Pharmacol
, vol.139
, pp. 765-774
-
-
Chi, X.1
Anselmi, A.2
Watkins, S.3
Gandhi, C.R.4
-
4
-
-
33751003841
-
Sustained activation of Racl in hepatic stellate cells promotes liver injury and fibrosis in mice
-
Choi SS, SicklickJK, Ma Q, Yang L, Huang J, Qi Y, Chen W, Li YX, Goldschmidt-Clermont PJ, Diehl AM. 2006. Sustained activation of Racl in hepatic stellate cells promotes liver injury and fibrosis in mice. Hepatology 44:1267-1277.
-
(2006)
Hepatology
, vol.44
, pp. 1267-1277
-
-
Choi, S.S.1
Sicklick, J.K.2
Ma, Q.3
Yang, L.4
Huang, J.5
Qi, Y.6
Chen, W.7
Li, Y.X.8
Goldschmidt-Clermont, P.J.9
Diehl, A.M.10
-
5
-
-
4344694893
-
The effects of oxidative stress on the liver sieve
-
Cogger VC, Muller M, Fraser R, McLean AJ, Khan J, Le Couteur DG. 2004. The effects of oxidative stress on the liver sieve. J Hepatol 41:370-376.
-
(2004)
J Hepatol
, vol.41
, pp. 370-376
-
-
Cogger, V.C.1
Muller, M.2
Fraser, R.3
McLean, A.J.4
Khan, J.5
Le Couteur, D.G.6
-
6
-
-
0031789130
-
Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor
-
Colell A, García-Ruiz C, Miranda M, Ardite E, Marí M, Morales A, Corrales F, Kaplowitz N, Fernández-Checa JC. 1998. Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor. Gastroenterology 115:1541-1551.
-
(1998)
Gastroenterology
, vol.115
, pp. 1541-1551
-
-
Colell, A.1
García-Ruiz, C.2
Miranda, M.3
Ardite, E.4
Marí, M.5
Morales, A.6
Corrales, F.7
Kaplowitz, N.8
Fernández-Checa, J.C.9
-
7
-
-
0025688897
-
Retinoic acid modulates rat Ito cell proliferation, collagen, and transforming growth factor beta production
-
Davis BH, Kramer RT, Davidson NO. 1990. Retinoic acid modulates rat Ito cell proliferation, collagen, and transforming growth factor beta production. J Clin Invest 86:2062-2070.
-
(1990)
J Clin Invest
, vol.86
, pp. 2062-2070
-
-
Davis, B.H.1
Kramer, R.T.2
Davidson, N.O.3
-
9
-
-
0034723290
-
Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
-
Friedman SL. 2000. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem 275:2247-2250.
-
(2000)
J Biol Chem
, vol.275
, pp. 2247-2250
-
-
Friedman, S.L.1
-
10
-
-
0026049520
-
-
Fumarulo R, Conese M, Riccardi S, Giordano D, Montemurro P, Colucci M, Semeraro N. l99l. Retinoids inhibit the respiratory burst and degranulation of stimulated human polymorphonuclear leukocytes. Agents Actions l99l. 34:339-342.
-
Fumarulo R, Conese M, Riccardi S, Giordano D, Montemurro P, Colucci M, Semeraro N. l99l. Retinoids inhibit the respiratory burst and degranulation of stimulated human polymorphonuclear leukocytes. Agents Actions l99l. 34:339-342.
-
-
-
-
11
-
-
20944451594
-
Oxidative stress stimulates proliferation and invasiveness of hepatic stellate cells via a MMP2-mediated mechanism
-
Galli A, Svegliati-Baroni G, Ceni E, Milani S, Ridolfi F, Salzano R, Tarocchi M, Grappone C, Pellegrini G, Benedetti A, Surrenti C, Casini A. 2005. Oxidative stress stimulates proliferation and invasiveness of hepatic stellate cells via a MMP2-mediated mechanism. Hepatology 41:1074-1084.
-
(2005)
Hepatology
, vol.41
, pp. 1074-1084
-
-
Galli, A.1
Svegliati-Baroni, G.2
Ceni, E.3
Milani, S.4
Ridolfi, F.5
Salzano, R.6
Tarocchi, M.7
Grappone, C.8
Pellegrini, G.9
Benedetti, A.10
Surrenti, C.11
Casini, A.12
-
12
-
-
0031932430
-
l998. Anendothelinreceptorantagonist TAK-044 ameliorates carbon tetrachloride-induced acute liver injury and portal hypertension in rats
-
GandhiCR,NemotoEM,WatkinsSC,SubbotinVM.l998. Anendothelinreceptorantagonist TAK-044 ameliorates carbon tetrachloride-induced acute liver injury and portal hypertension in rats. Liver 18:39-48.
-
Liver
, vol.18
, pp. 39-48
-
-
Gandhi, C.R.1
Nemoto, E.M.2
Watkins, S.C.3
Subbotin, V.M.4
-
13
-
-
0034808310
-
History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells
-
Geerts A. 2001. History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells. Semin Liver Dis 21:311-335.
-
(2001)
Semin Liver Dis
, vol.21
, pp. 311-335
-
-
Geerts, A.1
-
14
-
-
0001572310
-
Fat-storing, (Ito) cell biology
-
Arias IM, Boyer JL, Fasuto N, Jakoby WB, Schachter DL, Shafritz DA, eds, New York: Raven Press, Ltd. pp
-
Geerts A, DeBleser P, Hautekeete ML, Niki T, Wisse E. Fat-storing, (Ito) cell biology. 1994. In: Arias IM, Boyer JL, Fasuto N, Jakoby WB, Schachter DL, Shafritz DA, (eds). The liver: Biology and pathobiology. New York: Raven Press, Ltd. pp. 819-838.
-
(1994)
The liver: Biology and pathobiology
, pp. 819-838
-
-
Geerts, A.1
DeBleser, P.2
Hautekeete, M.L.3
Niki, T.4
Wisse, E.5
-
15
-
-
0032874845
-
Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress
-
Hayes JD, McLellan LI. 1999. Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress. Free Rad Res 31:273-300.
-
(1999)
Free Rad Res
, vol.31
, pp. 273-300
-
-
Hayes, J.D.1
McLellan, L.I.2
-
16
-
-
1442282022
-
Differential modulation of rat hepatic stellate phenotype by natural and synthetic retinoids
-
HellemansK,VerbuystP,QuartierE,SchuitF,RomboutsK,ChandraratnaRA, SchuppanD, Geerts A. 2004. Differential modulation of rat hepatic stellate phenotype by natural and synthetic retinoids. Hepatology 39:97-108.
-
(2004)
Hepatology
, vol.39
, pp. 97-108
-
-
Hellemans, K.1
Verbuyst, P.2
Quartier, E.3
Schuit, F.4
Rombouts, K.5
Chandraratna, R.A.6
Schuppan, D.7
Geerts, A.8
-
17
-
-
0034599103
-
Domain image-analysis program for the single-cell gel-electrophoresis (comet) assay
-
Helma C, Uhl MA. 2000. Domain image-analysis program for the single-cell gel-electrophoresis (comet) assay. Mutat Res 466:9-15.
-
(2000)
Mutat Res
, vol.466
, pp. 9-15
-
-
Helma, C.1
Uhl, M.A.2
-
18
-
-
14644412937
-
Protectiveeffect of baicalin on tert-butyl hydroperoxide-induced rat hepatotoxicity
-
HwangJM,WangCJ,ChouFP,TsengTH,HsiehYS,HsuJD,ChuCY.2005.Protectiveeffect of baicalin on tert-butyl hydroperoxide-induced rat hepatotoxicity. Arch Toxicol 79:102-109.
-
(2005)
Arch Toxicol
, vol.79
, pp. 102-109
-
-
Hwang, J.M.1
Wang, C.J.2
Chou, F.P.3
Tseng, T.H.4
Hsieh, Y.S.5
Hsu, J.D.6
Chu, C.Y.7
-
19
-
-
0032146551
-
-
IredaleJP, Benyon RC, Pickering J, McCullen M, Orthrop M, Pawley S, Hovell C, Arthur MJ. 1998. Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. J Clin Invest l02:538-549.
-
IredaleJP, Benyon RC, Pickering J, McCullen M, Orthrop M, Pawley S, Hovell C, Arthur MJ. 1998. Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. J Clin Invest l02:538-549.
-
-
-
-
21
-
-
0036828064
-
-
Knight TR, Ho YS, Farhood A, Jaeschke H. 2002. Peroxynitrite is a critical mediator of acetaminophenhepatotoxicityinmurinelivers: Protectionbyglutathione.JPharmacol Exp Ther 303:468-475.
-
Knight TR, Ho YS, Farhood A, Jaeschke H. 2002. Peroxynitrite is a critical mediator of acetaminophenhepatotoxicityinmurinelivers: Protectionbyglutathione.JPharmacol Exp Ther 303:468-475.
-
-
-
-
22
-
-
0038649824
-
Gliotoxin-mediated apoptosis of activated human hepatic stellate cells
-
KweonYO,PaikYH,SchnablB,QianT,LemastersJJ,BrennerDA.2003. Gliotoxin-mediated apoptosis of activated human hepatic stellate cells. J Hepatol 39:38-46.
-
(2003)
J Hepatol
, vol.39
, pp. 38-46
-
-
Kweon, Y.O.1
Paik, Y.H.2
Schnabl, B.3
Qian, T.4
Lemasters, J.J.5
Brenner, D.A.6
-
23
-
-
0035066383
-
200l. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis JM, Avruch J. 200l. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 81:807-869.
-
Physiol Rev
, vol.81
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
24
-
-
0028838193
-
Activation of hepatic stellate cells by TGF a and collagen type I is mediated byoxidative stress through c-myb expression
-
Lee KS, Buck S, Houglum K, Chojkier M. 1995. Activation of hepatic stellate cells by TGF a and collagen type I is mediated byoxidative stress through c-myb expression. JClin Invest 96:2461-2468.
-
(1995)
JClin Invest
, vol.96
, pp. 2461-2468
-
-
Lee, K.S.1
Buck, S.2
Houglum, K.3
Chojkier, M.4
-
25
-
-
0030774231
-
-
P-F, Dietz R, von Harsdorf R. l997. Differential effect of hydrogen peroxide and superoxide anion on apoptosis and proliferation of vascular smooth muscle cells. Circulation 96:3602-3609.
-
P-F, Dietz R, von Harsdorf R. l997. Differential effect of hydrogen peroxide and superoxide anion on apoptosis and proliferation of vascular smooth muscle cells. Circulation 96:3602-3609.
-
-
-
-
26
-
-
0032922492
-
DietzR,von HarsdorfR.l999.Superoxideinducesapoptosisin cardiomyocytes,but proliferation and expression of transforming growth factor-bl in cardiac fibroblasts
-
P-F,DietzR,von HarsdorfR.l999.Superoxideinducesapoptosisin cardiomyocytes,but proliferation and expression of transforming growth factor-bl in cardiac fibroblasts. FEBS Lett 448:206-210.
-
FEBS Lett
, vol.448
, pp. 206-210
-
-
P-F1
-
27
-
-
0035851123
-
-
L, Tao J, Davaille J, Feral C, Mallat A, Rieusset J, Vidal H, Lotersztajn S. 2001. l5-deoxy-Delta 12,14-prostaglandin J2 induces apoptosis of human hepatic myofibroblasts. A pathway involving oxidative stress independently of peroxisome-proliferator-activated receptors. J Biol Chem 276:38152-38158.
-
L, Tao J, Davaille J, Feral C, Mallat A, Rieusset J, Vidal H, Lotersztajn S. 2001. l5-deoxy-Delta 12,14-prostaglandin J2 induces apoptosis of human hepatic myofibroblasts. A pathway involving oxidative stress independently of peroxisome-proliferator-activated receptors. J Biol Chem 276:38152-38158.
-
-
-
-
28
-
-
1542330614
-
Role of reactive oxygen species, glutathione and NF-kappaB in apoptosis induced by 3,4-methylenedioxymethamphetamine (''Ecstasy'') on hepatic stellate cells
-
Montiel-Duarte C, Ansorena E, Lopez-Zabalza MJ, Cenarruzabeitia E, Iraburu MJ. 2004. Role of reactive oxygen species, glutathione and NF-kappaB in apoptosis induced by 3,4-methylenedioxymethamphetamine (''Ecstasy'') on hepatic stellate cells. Biochem Pharmacol 67:1025-1033.
-
(2004)
Biochem Pharmacol
, vol.67
, pp. 1025-1033
-
-
Montiel-Duarte, C.1
Ansorena, E.2
Lopez-Zabalza, M.J.3
Cenarruzabeitia, E.4
Iraburu, M.J.5
-
29
-
-
29244466499
-
-
Novo E, Marra F, Zamara E, Valfredi Bonzo L, Caligiuri A, Cannito S, Antonaci C, Colombatto S,Pinzani M,ParolaM.2006a.Dose-dependentand divergenteffects ofsuperoxideanion on cell death, proliferation and migration ofactivated human hepatic stellate cells. Gut 55:90-97.
-
Novo E, Marra F, Zamara E, Valfredi Bonzo L, Caligiuri A, Cannito S, Antonaci C, Colombatto S,Pinzani M,ParolaM.2006a.Dose-dependentand divergenteffects ofsuperoxideanion on cell death, proliferation and migration ofactivated human hepatic stellate cells. Gut 55:90-97.
-
-
-
-
30
-
-
33746120376
-
Overexpression ofBcl-2byactivatedhuman hepaticstellatecells:Resistancetoapoptosis as a mechanism of progressive hepatic fibrogenesis in humans
-
Novo E, Marra F, Zamara E, Valfre di Bonzo L, Monitillo L, Cannito S, Petrai I, Mazzocca A, Bonacchi A, De Franco RS, Colombatto S, Autelli R, Pinzani M, Parola M. 2006b. Overexpression ofBcl-2byactivatedhuman hepaticstellatecells:Resistancetoapoptosis as a mechanism of progressive hepatic fibrogenesis in humans. Gut 55:1174-1182.
-
(2006)
Gut
, vol.55
, pp. 1174-1182
-
-
Novo, E.1
Marra, F.2
Zamara, E.3
Valfre di Bonzo, L.4
Monitillo, L.5
Cannito, S.6
Petrai, I.7
Mazzocca, A.8
Bonacchi, A.9
De Franco, R.S.10
Colombatto, S.11
Autelli, R.12
Pinzani, M.13
Parola, M.14
-
31
-
-
0030755313
-
l997. Retinoids exacerbate rat liver fibrosis by inducing the activation of latent TGF-beta in liver stellate cells
-
Okuno M, Moriwaki H, Imai S, Muto Y, Kawada N, Suzuki Y, Kojima S. l997. Retinoids exacerbate rat liver fibrosis by inducing the activation of latent TGF-beta in liver stellate cells. Hepatology 26:913-921.
-
Hepatology
, vol.26
, pp. 913-921
-
-
Okuno, M.1
Moriwaki, H.2
Imai, S.3
Muto, Y.4
Kawada, N.5
Suzuki, Y.6
Kojima, S.7
-
32
-
-
0027226140
-
-
Parola M, Pinzani M, Casini A, Albano E, Poli G, Gentilini A, Gentilini P, Dianzani MU. l993. Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen alphal (I)geneexpressioninhumanliverfat- storingcells.BiochemBiophysResCommun 194:1044-1050.
-
Parola M, Pinzani M, Casini A, Albano E, Poli G, Gentilini A, Gentilini P, Dianzani MU. l993. Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen alphal (I)geneexpressioninhumanliverfat- storingcells.BiochemBiophysResCommun 194:1044-1050.
-
-
-
-
33
-
-
0029922315
-
Metals, oxidative stress and hepatic fibrosis
-
Pietrangelo A. 1996. Metals, oxidative stress and hepatic fibrosis. Sem Liver Dis 16:13-30.
-
(1996)
Sem Liver Dis
, vol.16
, pp. 13-30
-
-
Pietrangelo, A.1
-
34
-
-
0026525116
-
l992.Phenotypical modulationofliverfat- storingcellsby retinoids. Influence on unstimulated and growth factor-induced cell proliferation
-
Pinzani M,Gentilini P,AbboudHE.l992.Phenotypical modulationofliverfat- storingcellsby retinoids. Influence on unstimulated and growth factor-induced cell proliferation.J Hepatol 14:211-220.
-
J Hepatol
, vol.14
, pp. 211-220
-
-
Pinzani, M.1
Gentilini, P.2
Abboud, H.E.3
-
35
-
-
0030753059
-
l997. Oxygen-free radical-mediated injury to cultured rat hepatocytes during cold incubation in preservation solutions
-
Rauen U, Reuters I, Fuchs A, de Groot H. l997. Oxygen-free radical-mediated injury to cultured rat hepatocytes during cold incubation in preservation solutions. Hepatology 26:351-357.
-
Hepatology
, vol.26
, pp. 351-357
-
-
Rauen, U.1
Reuters, I.2
Fuchs, A.3
de Groot, H.4
-
36
-
-
0032910085
-
Cold-inducedapoptosis in cultured hepatocytes and liver endothelial cells: Mediation by reactive oxygen species
-
RauenU,PolzarB,StephanH,MannherzHG,DeGrootD.1999.Cold-inducedapoptosis in cultured hepatocytes and liver endothelial cells: Mediation by reactive oxygen species. FASEB J 13:155-168.
-
(1999)
FASEB J
, vol.13
, pp. 155-168
-
-
Rauen, U.1
Polzar, B.2
Stephan, H.3
Mannherz, H.G.4
DeGroot, D.5
-
37
-
-
0031915552
-
BenedettiA.l998. Fibrogeniceffectofoxidativestressonrat hepatic stellate cells
-
Svegliati Baroni G, D'Ambrosio L, Ferretti G, Casini A, Di Sario A, Salzano R, Ridolfi F, SaccomannoS,Jezequel AM,BenedettiA.l998. Fibrogeniceffectofoxidativestressonrat hepatic stellate cells. Hepatology 27:720-726.
-
Hepatology
, vol.27
, pp. 720-726
-
-
Svegliati Baroni, G.1
D'Ambrosio, L.2
Ferretti, G.3
Casini, A.4
Di Sario, A.5
Salzano, R.6
Ridolfi, F.7
SaccomannoS8
Jezequel, A.M.9
-
39
-
-
3042521640
-
EndothelinreceptorantagonistTAK- 044arrestsandreversesthedevelopmentofcarbon tetrachloride-induced cirrhosis in rats
-
Thirunavukkarasu C, Yang Y, Subbotin VM, Harvey SAK, Fung J, Gandhi CR. 2004b. EndothelinreceptorantagonistTAK- 044arrestsandreversesthedevelopmentofcarbon tetrachloride-induced cirrhosis in rats. Gut 53:1010-1019.
-
(2004)
Gut
, vol.53
, pp. 1010-1019
-
-
Thirunavukkarasu, C.1
Yang, Y.2
Subbotin, V.M.3
Harvey, S.A.K.4
Fung, J.5
Gandhi, C.R.6
-
40
-
-
21644434942
-
Normalrathepatic stellatecellsrespondtoendotoxininLBP-independentmannertoproduceinhibitor(s)of DNA synthesis in hepatocytes
-
ThirunavukkarasuC,UemuraT,WangLF,WatkinsSC,GandhiCR.2005.Normalrathepatic stellatecellsrespondtoendotoxininLBP-independentmannertoproduceinhibitor(s)of DNA synthesis in hepatocytes. J Cell Physiol 204:654-665.
-
(2005)
J Cell Physiol
, vol.204
, pp. 654-665
-
-
Thirunavukkarasu, C.1
Uemura, T.2
Wang, L.F.3
Watkins, S.C.4
Gandhi, C.R.5
-
41
-
-
33845627110
-
Effectsofretinoic acid on the development of liver fibrosis produced by carbon tetrachloride in mice
-
WangL,PotterJJ,Rennie-TankersleyL,NovitskiyG,SipesJ,MezeyE.2007. Effectsofretinoic acid on the development of liver fibrosis produced by carbon tetrachloride in mice. Biochim Biophys Acta 1772:66-71.
-
(2007)
Biochim Biophys Acta
, vol.1772
, pp. 66-71
-
-
Wang, L.1
Potter, J.J.2
Rennie-Tankersley, L.3
Novitskiy, G.4
Sipes, J.5
Mezey, E.6
-
42
-
-
0010471495
-
l994.Cellular defenses against damage from reactive oxygen species
-
Yu BP.l994.Cellular defenses against damage from reactive oxygen species. Pharmacol Rev 1994. 74:139-162.
-
(1994)
Pharmacol Rev
, vol.74
, pp. 139-162
-
-
Yu, B.P.1
-
43
-
-
33645233816
-
Metabolic insights into the hepatoprotective role of N-acetylcysteine in mouse liver
-
Zwingmann C, Bilodeau M. 2006. Metabolic insights into the hepatoprotective role of N-acetylcysteine in mouse liver. Hepatology 43:454-463.
-
(2006)
Hepatology
, vol.43
, pp. 454-463
-
-
Zwingmann, C.1
Bilodeau, M.2
|