Search algorithms as a framework for the optimization of drug combinations

PLoS Computational Biology

Volumn 4, Issue 12, 2008, Pages

  Calzolari, Diego ^a   Bruschi, Stefania ^a   Coquin, Laurence ^a   Schofield, Jennifer ^a   Feala, Jacob D ^b   Reed, John C ^a   McCulloch, Andrew D ^b   Paternostro, Giovanni ^a,b  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOINFORMATICS; DIGITAL COMMUNICATION SYSTEMS; DISEASE CONTROL; INFORMATION THEORY; LEARNING ALGORITHMS;

CLINICAL EXPERIENCE; CLINICAL OUTCOME; COMBINATION THERAPY; COMPLEX DISEASE; DRUG COMBINATIONS; NOVEL APPLICATIONS; OPTIMAL COMBINATION; OPTIMISATIONS; RANDOM SEARCHES; SEARCH ALGORITHMS;

CELL DEATH;

DEXAMETHASONE; DOXYCYCLINE; ETOPOSIDE; GOSSYPOL; RITUXIMAB; SODIUM SELENITE; VINCRISTINE; DRUG;

ALGORITHM; ARTICLE; CANCER CELL; CELL DEATH; COMPUTER MODEL; CONCEPTUAL FRAMEWORK; CONTROLLED STUDY; CYTOTOXICITY; DROSOPHILA MELANOGASTER; DRUG COMBINATION; ENGINEERING; EXERCISE; FACTORIAL ANALYSIS; FEMALE; HEART FUNCTION; HUMAN; HUMAN CELL; MALE; NONHUMAN; PHYSICS; SIMULATION; COMPUTER ASSISTED DRUG THERAPY; DECISION SUPPORT SYSTEM; DOSE RESPONSE; METHODOLOGY;

DROSOPHILA MELANOGASTER;

ALGORITHMS; DECISION SUPPORT TECHNIQUES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; DRUG THERAPY, COMPUTER-ASSISTED; PHARMACEUTICAL PREPARATIONS;

EID: 58149166733     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000249     Document Type: Article

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