Endothelial protein C receptor-assisted transport of activated protein C across the mouse blood-brain barrier

Journal of Cerebral Blood Flow and Metabolism

Volumn 29, Issue 1, 2009, Pages 25-33

  Deane, Rashid ^a   LaRue, Barbra ^a   Sagare, Abhay P ^a   Castellino, Francis J ^b   Zhong, Zhihui ^a   Zlokovic, Berislav V ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

Activated protein C; APC variants; Blood brain barrier; Endothelial protein C receptor; Transport

Indexed keywords

ACTIVATED PROTEIN C; ENDOTHELIAL PROTEIN C RECEPTOR; ENZYME VARIANT; PROTEIN C; PROTEINASE ACTIVATED RECEPTOR 1; RECOMBINANT PROTEIN;

ACTIVE TRANSPORT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTICOAGULATION; ARTICLE; BINDING AFFINITY; BINDING SITE; BLOOD BRAIN BARRIER; BRAIN CAPILLARY; BRAIN CIRCULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG TRANSPORT; DRUG UPTAKE; ENZYME ACTIVE SITE; FOREBRAIN; MEMBRANE TRANSPORT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT;

ANIMALS; BLOOD-BRAIN BARRIER; ENZYME ACTIVATION; GLYCOPROTEINS; KINETICS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN C; PROTEIN TRANSPORT;

EID: 58149154704     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2008.117     Document Type: Article

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