Regioselective addition of mesitol to a 2,4-dichloropyridine

Organic Process Research and Development

Volumn 12, Issue 3, 2008, Pages 411-413

  Ruggeri, Sally Gut ^a   Vanderplas, Brian C ^a   Anderson, Bruce G ^a   Breitenbach, Ralph ^a   Urban, Frank J ^a   Stewart III, A Morgan ^a   Young, Gregory R ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 58149149456     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op800004q     Document Type: Article

References (17)

1. Chen, Y. L.; Mansbach, R. S.; Winter, S. M.; Brooks, E.; Collins, J.; Corman, M. L.; Dunaiskis, A. R.; Faraci, W. S.; Gallaschun, R. J.; Schmidt, A.; Schultz, D. W. J. Med. Chem. 1997, 40, 1749.
2. Chen, Y. L. Corticotropin Releasing Factor Antagonists. U.S. Patent 5, 962, 479, October 5. 1999.
3. Mittelbach, M.; Schmidt, H.-W.; Uray, G.; Junek, H.; Lamm, B.; Ankner, K.; Brandstrom, A.; Simonsson, R. Acta Chem. Scand. B 1988, 524.
4. Prelog, V.; Szpilfogel, S. Helv. Chim. Acta 1942, 25. 1306.
5. Tiwari, A.; Riordan, J. M.; Waud, W. R.; Struck, R. F. J. Med. Chem. 2002, 45, 1079.
6. Brady, J. H.; Wakefield, B. J. Synthesis 1984, 33.
7. Mack, A. G; Suschitzky, H.; Wakefield, B. J. J. Chem. Soc., Perkin Trans. 1 1980, 1682.
8. Osborne, A. C.; Miller, L. A. D. J. Chem. Soc., Perkin Trans. 1 1993, 181.
9. Chen, J.; Steglich, W. J. Heterocycl. Chem. 1993, 30, 909.
10. Jarvest, R. L.; Armstrong, S. A.; Berge, J. M.; Brown, P.; Elder, J. S.; Brown, M. J.; Copley, R. C. B.; Forrest, A. K.; Hamprecht, D. W.; O'Hanlon, P. J.; Mitchell, D. J.; Rittenhouse, S.; Witty, D, R. Bioorg. Med. Chem. Lett. 2004, 14, 3937.
11. Rowlett. R. J.. Jr.; Lutz, R. E J. Am. Chem. Soc. 1946, 68, 1288.
12. (a) Hill, A. J; McGraw, W. J. J. Org. Chem. 1949, 14, 783.
13. Fujiwara, R; Kitagawa, K. Heterocycles 2000, 53, 409.
14. (a) Pellón, R. F.; Carrasco, R.; Millián, V.; Rodés, L. Synth. Commun. 1995, 25, 1077.
15. Fagan, P. J.; Hauptmann, E.; Shapiro, R.; Casalnuovo, A. J. Am. Chem. Soc. 2000. 122, 5043.
16. Schmidt, A.; Mordhorst, T.; Nieger, M. Synthesis 2006, 23, 3987.
17. Garcia, F.; Hopkins, A. D.; Kowenicki, R. A.; McPardin. M.; Rogers. M. C.; Wright, D. S. Organometallics 2004, 23, 3884.