메뉴 건너뛰기




Volumn 28, Issue 5, 2008, Pages 518-524

The alpha 2A-adrenergic receptor gene polymorphism modifies antidepressant responses to milnacipran

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2A ADRENERGIC RECEPTOR; ANTIDEPRESSANT AGENT; MILNACIPRAN; PAROXETINE; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; ADRENERGIC RECEPTOR AFFECTING AGENT; ALPHA 2 ADRENERGIC RECEPTOR; CYCLOPROPANE DERIVATIVE; RECEPTOR, ADRENERGIC, ALPHA 2A; RECEPTOR, ADRENERGIC, ALPHA-2A; UNCLASSIFIED DRUG;

EID: 58149139155     PISSN: 02710749     EISSN: None     Source Type: Journal    
DOI: 10.1097/JCP.0b013e31818455fc     Document Type: Article
Times cited : (35)

References (42)
  • 1
    • 33747396949 scopus 로고    scopus 로고
    • Effects of the serotonin type 2A, 3A and 3B receptor and the serotonin transporter genes on paroxetine and fluvoxamine efficacy and adverse drug reactions in depressed Japanese patients
    • Kato M, Fukuda T, Wakeno M, et al. Effects of the serotonin type 2A, 3A and 3B receptor and the serotonin transporter genes on paroxetine and fluvoxamine efficacy and adverse drug reactions in depressed Japanese patients. Neuropsychobiology. 2006;53:186-195.
    • (2006) Neuropsychobiology , vol.53 , pp. 186-195
    • Kato, M.1    Fukuda, T.2    Wakeno, M.3
  • 2
    • 0033807374 scopus 로고    scopus 로고
    • Allelic variation in the serotonin transporter promoter affects onset of paroxetine treatment response in late-life depression
    • Pollock BG, Ferrell RE, Mulsant BH, et al. Allelic variation in the serotonin transporter promoter affects onset of paroxetine treatment response in late-life depression. Neuropsychopharmacology. 2000;23: 587-590.
    • (2000) Neuropsychopharmacology , vol.23 , pp. 587-590
    • Pollock, B.G.1    Ferrell, R.E.2    Mulsant, B.H.3
  • 3
    • 0031736757 scopus 로고    scopus 로고
    • Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine
    • Smeraldi E, Zanardi R, Benedetti F, et al. Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine. Mol Psychiatry. 1998;3:508-511.
    • (1998) Mol Psychiatry , vol.3 , pp. 508-511
    • Smeraldi, E.1    Zanardi, R.2    Benedetti, F.3
  • 4
    • 0034677021 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphism and antidepressant response
    • Kim DK, Lim SW, Lee S, et al. Serotonin transporter gene polymorphism and antidepressant response. Neuroreport. 2000;11:215-219.
    • (2000) Neuroreport , vol.11 , pp. 215-219
    • Kim, D.K.1    Lim, S.W.2    Lee, S.3
  • 5
    • 4444308435 scopus 로고    scopus 로고
    • Prediction of antidepressant response to milnacipran by norepinephrine transporter gene polymorphisms
    • Yoshida K, Takahashi H, Higuchi H, et al. Prediction of antidepressant response to milnacipran by norepinephrine transporter gene polymorphisms. Am J Psychiatry. 2004;161:1575-1580.
    • (2004) Am J Psychiatry , vol.161 , pp. 1575-1580
    • Yoshida, K.1    Takahashi, H.2    Higuchi, H.3
  • 6
    • 33749335980 scopus 로고    scopus 로고
    • Monoamine transporter gene polymorphisms and antidepressant response in Koreans with late-life depression
    • Kim H, Lim SW, Kim S, et al. Monoamine transporter gene polymorphisms and antidepressant response in Koreans with late-life depression. JAMA. 2006;296:1609-1618.
    • (2006) JAMA , vol.296 , pp. 1609-1618
    • Kim, H.1    Lim, S.W.2    Kim, S.3
  • 7
    • 0033232510 scopus 로고    scopus 로고
    • Role of norepinephrine in the pathophysiology and treatment of mood disorders
    • Ressler KJ, Nemeroff CB. Role of norepinephrine in the pathophysiology and treatment of mood disorders. Biol Psychiatry. 1999;46: 1291-1233.
    • (1999) Biol Psychiatry , vol.46 , pp. 1291-1233
    • Ressler, K.J.1    Nemeroff, C.B.2
  • 8
    • 10644271666 scopus 로고    scopus 로고
    • The C(-1019)G polymorphism of the 5-HT1A gene promoter and antidepressant response in mood disorders: Preliminary findings
    • Serretti A, Artioli P, Lorenzi C, et al. The C(-1019)G polymorphism of the 5-HT1A gene promoter and antidepressant response in mood disorders: preliminary findings. Int J Neuropsychopharmacol. 2004;7: 453-460.
    • (2004) Int J Neuropsychopharmacol , vol.7 , pp. 453-460
    • Serretti, A.1    Artioli, P.2    Lorenzi, C.3
  • 9
    • 33748582618 scopus 로고    scopus 로고
    • Association study of two serotonin 1A receptor gene polymorphisms and fluoxetine treatment response in Chinese major depressive disorders
    • Yu YW, Tsai SJ, Liou YJ, et al. Association study of two serotonin 1A receptor gene polymorphisms and fluoxetine treatment response in Chinese major depressive disorders. Eur Neuropsychopharmacol. 2006; 16:498-503.
    • (2006) Eur Neuropsychopharmacol , vol.16 , pp. 498-503
    • Yu, Y.W.1    Tsai, S.J.2    Liou, Y.J.3
  • 10
    • 0041765759 scopus 로고    scopus 로고
    • Differential control of adrenal and sympathetic catecholamine release by alpha 2-adrenoceptor subtypes
    • Brede M, Nagy G, Philipp M, et al. Differential control of adrenal and sympathetic catecholamine release by alpha 2-adrenoceptor subtypes. Mol Endocrinol. 2003;17:1640-1646.
    • (2003) Mol Endocrinol , vol.17 , pp. 1640-1646
    • Brede, M.1    Nagy, G.2    Philipp, M.3
  • 11
    • 0036337129 scopus 로고    scopus 로고
    • Physiological significance of alpha(2)- adrenergic receptor subtype diversity: One receptor is not enough
    • Philipp M, Brede M, Hein L. Physiological significance of alpha(2)- adrenergic receptor subtype diversity: one receptor is not enough. Am J Physiol Regul Integr Comp Physiol. 2002;283:287-295.
    • (2002) Am J Physiol Regul Integr Comp Physiol , vol.283 , pp. 287-295
    • Philipp, M.1    Brede, M.2    Hein, L.3
  • 12
    • 0035865579 scopus 로고    scopus 로고
    • 2O PET study of the neuromodulatory effects of clonidine
    • 2O PET study of the neuromodulatory effects of clonidine. Biol Psychiatry. 2001;49:317-325.
    • (2001) Biol Psychiatry , vol.49 , pp. 317-325
    • Fu, C.H.Y.1    Reed, L.J.2    Meyer, J.H.3
  • 13
    • 0345391014 scopus 로고    scopus 로고
    • Up-regulation of immunolabeled a2A-adrenoceptors, Gi coupling proteins, and regulatory receptor kinases in the prefrontal cortex of depressed suicides
    • García-Sevilla JA, Escriba PV, Ozaita A, et al. Up-regulation of immunolabeled a2A-adrenoceptors, Gi coupling proteins, and regulatory receptor kinases in the prefrontal cortex of depressed suicides. JNeurochem. 1999;72:282-291.
    • (1999) JNeurochem , vol.72 , pp. 282-291
    • García-Sevilla, J.A.1    Escriba, P.V.2    Ozaita, A.3
  • 14
    • 0036373345 scopus 로고    scopus 로고
    • Neurotrans- mitter receptor-mediated activation of G-proteins in brains of suicide victims with mood disorders: Selective supersensitivity of alpha(2A)- adrenoceptors
    • Gonzalez-Maeso J, Rodriguez-Puertas R, Meana JJ, et al. Neurotrans- mitter receptor-mediated activation of G-proteins in brains of suicide victims with mood disorders: selective supersensitivity of alpha(2A)- adrenoceptors. Neuropsychopharmacology. 2002;7:755-767.
    • (2002) Neuropsychopharmacology , vol.7 , pp. 755-767
    • Gonzalez-Maeso, J.1    Rodriguez-Puertas, R.2    Meana, J.J.3
  • 15
    • 0038659418 scopus 로고    scopus 로고
    • α2A and α2C-adrenoceptor regulation in the brain: α2A changes persist after chronic stress
    • Flügge G, van Kampen M, Meyer H, et al. α2A and α2C-adrenoceptor regulation in the brain: α2A changes persist after chronic stress. Eur J Neurosci. 2003;17:917-928.
    • (2003) Eur J Neurosci , vol.17 , pp. 917-928
    • Flügge, G.1    van Kampen, M.2    Meyer, H.3
  • 16
    • 0019785727 scopus 로고
    • 2-adrenergic receptors in major depressive disorder: Binding of tritiated cloni- dine before and after tricyclic antidepressant drug treatment
    • 2-adrenergic receptors in major depressive disorder: binding of tritiated cloni- dine before and after tricyclic antidepressant drug treatment. Arch Gen Psychiatry. 1981;38:1327-1333.
    • (1981) Arch Gen Psychiatry , vol.38 , pp. 1327-1333
    • García-Sevilla, J.A.1    Zis, A.P.2    Hollingsworth, P.J.3
  • 17
    • 0025157158 scopus 로고
    • 2- adrenoceptor-mediated inhibition of platelet adenylate cyclase and induction of aggregation in major depression
    • 2- adrenoceptor-mediated inhibition of platelet adenylate cyclase and induction of aggregation in major depression. Arch Gen Psychiatry. 1990;47:125-132.
    • (1990) Arch Gen Psychiatry , vol.47 , pp. 125-132
    • Garcia-Sevilla, J.A.1    Padro, D.2    Giralt, M.T.3
  • 18
    • 0033589882 scopus 로고    scopus 로고
    • Gurguis GN, Vo SP, Griffith JM, et al. Platelet alpha2A-adrenoceptor function in major depression: Gi coupling, effects of imipramine and relationship to treatment outcome. Psychiatry Res. 1999;89:73-95.
    • Gurguis GN, Vo SP, Griffith JM, et al. Platelet alpha2A-adrenoceptor function in major depression: Gi coupling, effects of imipramine and relationship to treatment outcome. Psychiatry Res. 1999;89:73-95.
  • 19
    • 0030908607 scopus 로고    scopus 로고
    • Brain alpha- adrenoceptors in depressed suicides
    • De Paermentier F, Mauger JM, Lowther S, et al. Brain alpha- adrenoceptors in depressed suicides. Brain Res. 1997;757:60-68.
    • (1997) Brain Res , vol.757 , pp. 60-68
    • De Paermentier, F.1    Mauger, J.M.2    Lowther, S.3
  • 20
    • 3242774471 scopus 로고    scopus 로고
    • Increased mRNA expression of alpha2A-adrenoceptors, serotonin receptors and mu-opioid receptors in the brains of suicide victims
    • Escriba PV, Ozaita A, Garcia-Sevilla JA. Increased mRNA expression of alpha2A-adrenoceptors, serotonin receptors and mu-opioid receptors in the brains of suicide victims. Neuropsychopharmacology. 2004;29: 1512-1521.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1512-1521
    • Escriba, P.V.1    Ozaita, A.2    Garcia-Sevilla, J.A.3
  • 21
    • 0026548740 scopus 로고
    • Alpha 2-adrenoceptors in the brain of suicide victims: Increased receptor density associated with major depression
    • Meana JJ, Barturen F, Garcia-Sevilla JA. Alpha 2-adrenoceptors in the brain of suicide victims: increased receptor density associated with major depression. Biol Psychiatry. 1992;31:471-490.
    • (1992) Biol Psychiatry , vol.31 , pp. 471-490
    • Meana, J.J.1    Barturen, F.2    Garcia-Sevilla, J.A.3
  • 22
    • 0035399969 scopus 로고    scopus 로고
    • The alpha(2a)-adrenergic receptor plays a protective role in mouse behavioral models of depression and anxiety
    • Schramm NL, McDonald MP, Limbird LE. The alpha(2a)-adrenergic receptor plays a protective role in mouse behavioral models of depression and anxiety. J Neurosci. 2001;21:4875-4882.
    • (2001) J Neurosci , vol.21 , pp. 4875-4882
    • Schramm, N.L.1    McDonald, M.P.2    Limbird, L.E.3
  • 23
    • 32844466056 scopus 로고    scopus 로고
    • Further evidence of the involvement of alpha-2A-adrenergic receptor gene (ADRA2A) in inattentive dimensional scores of attention-deficit/hyperactivity disorder
    • Roman T, Polanczyk GV, Zeni C, et al. Further evidence of the involvement of alpha-2A-adrenergic receptor gene (ADRA2A) in inattentive dimensional scores of attention-deficit/hyperactivity disorder. Mol Psychiatry. 2006;11:8-10.
    • (2006) Mol Psychiatry , vol.11 , pp. 8-10
    • Roman, T.1    Polanczyk, G.V.2    Zeni, C.3
  • 24
    • 33750458363 scopus 로고    scopus 로고
    • Association between alpha-2a- adrenergic receptor gene and ADHD inattentive type
    • Schmitz M, Denardin D, Silva TL, et al. Association between alpha-2a- adrenergic receptor gene and ADHD inattentive type. Biol Psychiatry. 2006;60:1028-1033.
    • (2006) Biol Psychiatry , vol.60 , pp. 1028-1033
    • Schmitz, M.1    Denardin, D.2    Silva, T.L.3
  • 25
    • 33747325407 scopus 로고    scopus 로고
    • The adrenergic receptor alpha- 2A gene (ADRA2A) and neuropsychological executive functions as putative endophenotypes for childhood ADHD
    • Waldman ID, Nigg JT, Gizer IR, et al. The adrenergic receptor alpha- 2A gene (ADRA2A) and neuropsychological executive functions as putative endophenotypes for childhood ADHD. Cogn Affect Behav Neurosci. 2006;6:18-30.
    • (2006) Cogn Affect Behav Neurosci , vol.6 , pp. 18-30
    • Waldman, I.D.1    Nigg, J.T.2    Gizer, I.R.3
  • 26
    • 0038417098 scopus 로고    scopus 로고
    • A "line item" approach to the identification of genes involved in polygenic behavioral disorders: The adrenergic alpha2A (ADRA2A) gene
    • Comings DE, Gonzalez NS, Cheng Li SC, et al. A "line item" approach to the identification of genes involved in polygenic behavioral disorders: the adrenergic alpha2A (ADRA2A) gene. Am J Med Genet B Neuro- psychiatr Genet. 2003;118:110-114.
    • (2003) Am J Med Genet B Neuro- psychiatr Genet , vol.118 , pp. 110-114
    • Comings, D.E.1    Gonzalez, N.S.2    Cheng Li, S.C.3
  • 27
    • 33745013199 scopus 로고    scopus 로고
    • Weight gain associated with the alpha2a-adrenergic receptor -1,291 C/G polymorphism and olanzapine treatment
    • Park YM, Chung YC, Lee SH, et al. Weight gain associated with the alpha2a-adrenergic receptor -1,291 C/G polymorphism and olanzapine treatment. Am JMed Genet B Neuropsychiatr Genet. 2006;141:394-397.
    • (2006) Am JMed Genet B Neuropsychiatr Genet , vol.141 , pp. 394-397
    • Park, Y.M.1    Chung, Y.C.2    Lee, S.H.3
  • 28
    • 25144477595 scopus 로고    scopus 로고
    • Polymorphism of the adrenergic receptor alpha 2a -1291C>G genetic variation and clozapine-induced weight gain
    • Wang YC, Bai YM, Chen JY, et al. Polymorphism of the adrenergic receptor alpha 2a -1291C>G genetic variation and clozapine-induced weight gain. J Neural Transm. 2005;112:1463-1468.
    • (2005) J Neural Transm , vol.112 , pp. 1463-1468
    • Wang, Y.C.1    Bai, Y.M.2    Chen, J.Y.3
  • 29
    • 0024410591 scopus 로고
    • Cloning, sequence analysis, and permanent expression of a human alpha 2-adrenergic receptor in Chinese hamster ovary cells
    • Fraser CM, Arakawa S, McCombie WR, et al. Cloning, sequence analysis, and permanent expression of a human alpha 2-adrenergic receptor in Chinese hamster ovary cells. J Biol Chem. 1989;264:11754-11761.
    • (1989) J Biol Chem , vol.264 , pp. 11754-11761
    • Fraser, C.M.1    Arakawa, S.2    McCombie, W.R.3
  • 30
    • 65949107297 scopus 로고    scopus 로고
    • First MB, Spitzer RL, Gibbon M, et al. Structured Clinical Interview for DSM-IVAxis I Disorders-Patient Edition SCID-I/P Version 2.0, New York: Biometrics Research Department, New York State Psychiatric Institute; 1995
    • First MB, Spitzer RL, Gibbon M, et al. Structured Clinical Interview for DSM-IVAxis I Disorders-Patient Edition (SCID-I/P Version 2.0). New York: Biometrics Research Department, New York State Psychiatric Institute; 1995.
  • 31
    • 0014186152 scopus 로고
    • Development of a rating scale for primary depressive illness
    • Hamilton M. Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol. 1967;6:278-296.
    • (1967) Br J Soc Clin Psychol , vol.6 , pp. 278-296
    • Hamilton, M.1
  • 32
    • 0030932778 scopus 로고    scopus 로고
    • Mspl identifies a biallelic polymorphism in the promoter region of the alpha 2A-adrenergic receptor gene
    • Lario S, Calls J, Cases A, et al. Mspl identifies a biallelic polymorphism in the promoter region of the alpha 2A-adrenergic receptor gene. Clin Genet. 1997;51:129-130.
    • (1997) Clin Genet , vol.51 , pp. 129-130
    • Lario, S.1    Calls, J.2    Cases, A.3
  • 34
    • 1642539048 scopus 로고    scopus 로고
    • Associations between baseline plasma MHPG (3-methoxy-4-hydroxyphenylglycol) levels and clinical responses with respect to milnacipran versus paroxetine treatment
    • Shinkai K, Yoshimura R, Ueda N, et al. Associations between baseline plasma MHPG (3-methoxy-4-hydroxyphenylglycol) levels and clinical responses with respect to milnacipran versus paroxetine treatment. JClin Psychopharmacol. 2004;24:11-17.
    • (2004) JClin Psychopharmacol , vol.24 , pp. 11-17
    • Shinkai, K.1    Yoshimura, R.2    Ueda, N.3
  • 35
    • 8844279169 scopus 로고    scopus 로고
    • A comparative study of milnacip- ran and paroxetine in outpatients with major depression
    • Sechter D, Vandel P, Weiller E, et al. A comparative study of milnacip- ran and paroxetine in outpatients with major depression. JAffect Disord. 2004;83:233-236.
    • (2004) JAffect Disord , vol.83 , pp. 233-236
    • Sechter, D.1    Vandel, P.2    Weiller, E.3
  • 36
    • 0036788326 scopus 로고    scopus 로고
    • Inhibition of norepinephrine uptake in patients with major depression treated with paroxetine
    • Gilmor ML, Owens MJ, Nemeroff CB. Inhibition of norepinephrine uptake in patients with major depression treated with paroxetine. Am J Psychiatry. 2002;159:1702-1710.
    • (2002) Am J Psychiatry , vol.159 , pp. 1702-1710
    • Gilmor, M.L.1    Owens, M.J.2    Nemeroff, C.B.3
  • 37
    • 0032507645 scopus 로고    scopus 로고
    • Polymorphism in the promoter region of the alpha 2A adrenergic receptor gene and mood disorders
    • Ohara K, Nagai M, Tani K, et al. Polymorphism in the promoter region of the alpha 2A adrenergic receptor gene and mood disorders. Neuroreport. 1998;9:1291-1294.
    • (1998) Neuroreport , vol.9 , pp. 1291-1294
    • Ohara, K.1    Nagai, M.2    Tani, K.3
  • 38
    • 1542314895 scopus 로고    scopus 로고
    • Alpha 2A adrenergic receptor gene and suicide
    • Sequeira A, Mamdani F, Lalovic A, et al. Alpha 2A adrenergic receptor gene and suicide. Psychiatry Res. 2004;125:87-93.
    • (2004) Psychiatry Res , vol.125 , pp. 87-93
    • Sequeira, A.1    Mamdani, F.2    Lalovic, A.3
  • 39
    • 33846881796 scopus 로고    scopus 로고
    • Association of the adrenergic alpha2A receptor gene with methylphenidate improvement of inattentive symptoms in children and adolescents with attention-deficit/hyper- activity disorder
    • Polanczyk G, Zeni C, Genro JP, et al. Association of the adrenergic alpha2A receptor gene with methylphenidate improvement of inattentive symptoms in children and adolescents with attention-deficit/hyper- activity disorder. Arch Gen Psychiatry. 2007;64:218-224.
    • (2007) Arch Gen Psychiatry , vol.64 , pp. 218-224
    • Polanczyk, G.1    Zeni, C.2    Genro, J.P.3
  • 40
    • 79959503826 scopus 로고    scopus 로고
    • The international HapMap project
    • HapMap Anonymous. The international HapMap project. Nature. 2003; 426(6968):789-796.
    • (2003) Nature , vol.426 , Issue.6968 , pp. 789-796
    • Anonymous, H.1
  • 41
    • 29744446276 scopus 로고    scopus 로고
    • Is dose escalation of antide- pressants a rational strategy after a medium-dose treatment has failed? A systematic review
    • Adli M, Baethge C, Heinz A, et al. Is dose escalation of antide- pressants a rational strategy after a medium-dose treatment has failed? A systematic review. Eur Arch Psychiatry Clin Neurosci. 2005; 255(6):387-400.
    • (2005) Eur Arch Psychiatry Clin Neurosci , vol.255 , Issue.6 , pp. 387-400
    • Adli, M.1    Baethge, C.2    Heinz, A.3
  • 42
    • 0033989126 scopus 로고    scopus 로고
    • Practice guideline for the treatment of patients with major depressive disorder (revision)
    • American Psychiatric Association
    • American Psychiatric Association. Practice guideline for the treatment of patients with major depressive disorder (revision). Am J Psychiatry. 2000;157(4 suppl):1-45.
    • (2000) Am J Psychiatry , vol.157 , Issue.4 SUPPL. , pp. 1-45


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.