Dexamethasone differentially regulates renal and duodenal calcium-processing genes in calbindin-D9k and -D28k knockout mice

Experimental Physiology

Volumn 94, Issue 1, 2009, Pages 138-151

  Kim, Man Hee ^a   Lee, Geun Shik ^a   Jung, Eui Man ^a   Choi, Kyung Chul ^a,b   Oh, Goo Taeg ^c   Jeung, Eui Bae ^a  

^a Chungbuk National University   (South Korea)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c Ewha Womans University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CALBINDIN; CORTICOSTERONE; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; MESSENGER RNA; PARATHYROID HORMONE RECEPTOR; PLASMA MEMBRANE CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SODIUM CALCIUM EXCHANGE PROTEIN; VANILLOID RECEPTOR 5; VANILLOID RECEPTOR 6; VITAMIN D RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DUODENUM; GENE CONTROL; GENETIC TRANSCRIPTION; KIDNEY; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

EID: 58149127357     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2008.044339     Document Type: Article

References (57)

1. Abou-Samra AB, Juppner H, Force T, Freeman MW, Kong XF, Schipani E et al 1992). Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol trisphosphates and increases intracellular free calcium. Proc Natl Acad Sci U S A 89, 2732 2736.
2. Airaksinen MS, Eilers J, Garaschuk O, Thoenen H, Konnerth A & Meyer M (1997). Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene. Proc Natl Acad Sci U S A 94, 1488 1493.
3. 2+ absorption in small intestine. Arch Biochem Biophys 460, 227 232.
4. 2+ channels in renal epithelial cells by parathyroid hormone. Nature 347, 388 391.
5. Barley NF, Prathalingam SR, Zhi P, Legon S, Howard A & Walters JR (1999). Factors involved in the duodenal expression of the human calbindin-D9k gene. Biochem J 341, 491 500.
6. Beaulieu JF & Calvert R (1985). Influences of dexamethasone on the maturation of fetal mouse intestinal mucosa in organ culture. Comp Biochem Physiol A 82, 91 95.
7. Besnard P, Jousset V & Garel JM (1989). Additive effects of dexamethasone and calcium on the calcitonin mRNA level in adrenalectomized rats. FEBS Lett 258, 293 296.
8. Bikle DD, Halloran B, Fong L, Steinbach L & Shellito J (1993). Elevated 1,25-dihydroxyvitamin D levels in patients with chronic obstructive pulmonary disease treated with prednisone. J Clin Endocrinol Metab 76, 456 461.
9. Bindels RJ (1993). Calcium handling by the mammalian kidney. J Exp Biol 184, 89 104.
10. Chailley-Heu B, Rambaud C, Barlier-Mur AM, Galateau-Salle F, Perret C, Capron F & Lacaze-Masmonteil T (2001). A model of pulmonary adenocarcinoma in transgenic mice expressing the simian virus 40 T antigen driven by the rat Calbindin-D9K (CaBP9K) promoter. J Pathol 195, 482 489.
11. Choi KC, Leung PC & Jeung EB (2005). Biology and physiology of Calbindin-D9k in female reproductive tissues: involvement of steroids and endocrine disruptors. Reprod Biol Endocrinol 3, 66.
12. Cole MA, Kim PJ, Kalman BA & Spencer RL (2000). Dexamethasone suppression of corticosteroid secretion: evaluation of the site of action by receptor measures and functional studies. Psychoneuroendocrinology 25, 151 167.
13. 3-response element in the 5′-flanking region of the rat calbindin D-9k gene. Proc Natl Acad Sci U S A 89, 603 607.
14. Farman N, Oblin ME, Lombes M, Delahaye F, Westphal HM, Bonvalet JP & Gasc JM (1991). Immunolocalization of gluco- and mineralocorticoid receptors in rabbit kidney. Am J Physiol Cell Physiol 260, C226 C233.
15. Frick KK & Bushinsky DA (2003). Molecular mechanisms of primary hypercalciuria. J Am Soc Nephrol 14, 1082 1095.
16. Fukugawa M & Kurokawa K (2002). Calcium homeostasis and imbalance. Nephron 92 (Suppl 1 41 45.
17. 28K knockout mice. J Am Soc Nephrol 17, 3020 3027.
18. 2+ reabsorption in the distal nephron. Annu Rev Physiol 64, 529 549.
19. Hurwitz S (1996). Homeostatic control of plasma calcium concentration. Crit Rev Biochem Mol Biol 31, 41 100.
20. 2+ channel TRPV6. Am J Physiol Gastrointest Liver Physiol 292, G92 G97.
21. Iacopino AM & Christakos S (1990). Corticosterone regulates calbindin-D28k mRNA and protein levels in rat hippocampus. J Biol Chem 265, 10177 10180.
22. Juppner H, Abou-Samra AB, Freeman M, Kong XF, Schipani E, Richards J et al 1991). A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide. Science 254, 1024 1026.
23. Kimberg DV, Baerg RD, Gershon E & Graudusius RT (1971). Effect of cortisone treatment on the active transport of calcium by the small intestine. J Clin Invest 50, 1309 1321.
24. Kutuzova GD, Akhter S, Christakos S, Vanhooke J, Kimmel-Jehan C & Deluca HF (2006). Calbindin D(9k) knockout mice are indistinguishable from wild-type mice in phenotype and serum calcium level. Proc Natl Acad Sci U S A 103, 12377 12381.
25. 2+ transport. EMBO J 25, 2978 2988.
26. Lee GS, Choi KC & Jeung EB (2006). Glucocorticoids differentially regulate expression of duodenal and renal calbindin-D9k through glucocorticoid receptor-mediated pathway in mouse model. Am J Physiol Endocrinol Metab 290, E299 E307.
27. Lee GS, Lee KY, Choi KC, Ryu YH, Paik SG, Oh GT & Jeung EB (2007). Phenotype of a calbindin-D9k gene knockout is compensated for by the induction of other calcium transporter genes in a mouse model. J Bone Miner Res 22, 1968 1978.
28. 3 of calbindin-D9k and calbindin-D28k gene expression in mouse kidney. Endocrinology 128, 2844 2852.
29. Li YC, Bolt MJ, Cao LP & Sitrin MD (2001). Effects of vitamin D receptor inactivation on the expression of calbindins and calcium metabolism. Am J Physiol Endocrinol Metab 281, E558 E564.
30. Lukert BP & Raisz LG (1990). Glucocorticoid-induced osteoporosis: pathogenesis and management. Ann Intern Med 112, 352 364.
31. McCuaig KA, Lee HS, Clarke JC, Assar H, Horsford J & White JH (1995). Parathyroid hormone/parathyroid hormone related peptide receptor gene transcripts are expressed from tissue-specific and ubiquitous promoters. Nucleic Acids Res 23, 1948 1955.
32. McGowan JE, Sysyn G, Petersson KH, Sadowska GB, Mishra OP, Delivoria-Papadopoulos M & Stonestreet BS (2000). Effect of dexamethasone treatment on maturational changes in the NMDA receptor in sheep brain. J Neurosci 20, 7424 7429.
33. Mazziotti G, Angeli A, Bilezikian JP, Canalis E & Giustina A (2006). Glucocorticoid-induced osteoporosis: an update. Trends Endocrinol Metab 17, 144 149.
34. Merot J, Bidet M, Gachot B, Le Maout S, Koechlin N, Tauc M & Poujeol P (1989). Electrical properties of rabbit early distal convoluted tubule in primary culture. Am J Physiol Renal Physiol 257, F288 F299.
35. Nagpal S, Na S & Rathnachalam R (2005). Noncalcemic actions of vitamin D receptor ligands. Endocr Rev 26, 662 687.
36. Panda DK, Miao D, Bolivar I, Li J, Huo R, Hendy GN & Goltzman D (2004). Inactivation of the 25-hydroxyvitamin D 1α-hydroxylase and vitamin D receptor demonstrates independent and interdependent effects of calcium and vitamin D on skeletal and mineral homeostasis. J Biol Chem 279, 16754 16766.
37. Patschan D, Loddenkemper K & Buttgereit F (2001). Molecular mechanisms of glucocorticoid-induced osteoporosis. Bone 29, 498 505.
38. Pausova Z, Bourdon J, Clayton D, Mattei MG, Seldin MF, Janicic N et al 1994). Cloning of a parathyroid hormone/parathyroid hormone-related peptide receptor (PTHR) cDNA from a rat osteosarcoma (UMR 106) cell line: chromosomal assignment of the gene in the human, mouse, and rat genomes. Genomics 20, 20 26.
39. 2+ transport and beyond. J Physiol 551, 729 740.
40. Rabadan-Diehl C & Aguilera G (1998). Glucocorticoids increase vasopressin V1b receptor coupling to phospholipase C. Endocrinology 139, 3220 3226.
41. Reichel H, Koeffler HP & Norman AW (1989). The role of the vitamin D endocrine system in health and disease. N Engl J Med 320, 980 991.
42. Reid IR (1997). Glucocorticoid osteoporosis - mechanisms and management. Eur J Endocrinol 137, 209 217.
43. Reid IR & Ibbertson HK (1987). Evidence for decreased tubular reabsorption of calcium in glucocorticoid-treated asthmatics. Horm Res 27, 200 204.
44. Reid IR, Veale AG & France JT (1994). Glucocorticoid osteoporosis. J Asthma 31, 7 18.
45. Rouleau MF, Mitchell J & Goltzman D (1988). In vivo distribution of parathyroid hormone receptors in bone: evidence that a predominant osseous target cell is not the mature osteoblast. Endocrinology 123, 187 191.
46. Rubin MR & Bilezikian JP (2002). Clinical review 151: The role of parathyroid hormone in the pathogenesis of glucocorticoid-induced osteoporosis: a re-examination of the evidence. J Clin Endocrinol Metab 87, 4033 4041.
47. Schweizer-Groyer G, Cadepond F, Jibard N, Neau E, Segard-Maurel I, Baulieu EE & Groyer A (1997). Stimulation of transcription in vitro from a liver-specific promoter by human glucocorticoid receptor (hGRα). Biochem J 324, 823 831.
48. Sheppard KE, Li KX & Autelitano DJ (1999). Corticosteroid receptors and 11β-hydroxysteroid dehydrogenase isoforms in rat intestinal epithelia. Am J Physiol Gastrointest Liver Physiol 277, G541 G547.
49. Shultz TD, Bollman S & Kumar R (1982). Decreased intestinal calcium absorption in vivo and normal brush border membrane vesicle calcium uptake in cortisol-treated chickens: evidence for dissociation of calcium absorption from brush border vesicle uptake. Proc Natl Acad Sci U S A 79, 3542 3546.
50. Tohmon M, Fukase M, Kishihara M, Kadowaki S & Fujita T (1988). Effect of glucocorticoid administration on intestinal, renal, and cerebellar calbindin-D28K in chicks. J Bone Miner Res 3, 325 331.
51. van Abel M, Hoenderop JG & Bindels RJ (2005). The epithelial calcium channels TRPV5 and TRPV6: regulation and implications for disease. Naunyn Schmiedebergs Arch Pharmacol 371, 295 306.
52. Van Cromphaut SJ, Dewerchin M, Hoenderop JG, Stockmans I, Van Herck E, Kato S, Bindels RJ, Collen D, Carmeliet P, Bouillon R & Carmeliet G (2001). Duodenal calcium absorption in vitamin D receptor-knockout mice: functional and molecular aspects. Proc Natl Acad Sci U S A 98, 13324 13329.
53. Van Cromphaut SJ, Stockmans I, Torrekens S, Van Herck E, Carmeliet G & Bouillon R (2007). Duodenal calcium absorption in dexamethasone-treated mice: functional and molecular aspects. Arch Biochem Biophys 460, 300 305.
54. Walters JR (1989). Calbindin-D9k stimulates the calcium pump in rat enterocyte basolateral membranes. Am J Physiol Gastrointest Liver Physiol 256, G124 G128.
55. Wasserman RH & Fullmer CS (1995). Vitamin D and intestinal calcium transport: facts, speculations and hypotheses. J Nutr 125, 1971S 1979S.
56. Weinstein RS, Jilka RL, Parfitt AM & Manolagas SC (1998). Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone. J Clin Invest 102, 274 282.
57. Zheng W, Xie Y, Li G, Kong J, Feng JQ & Li YC (2004). Critical role of calbindin-D28k in calcium homeostasis revealed by mice lacking both vitamin D receptor and calbindin-D28k. J Biol Chem 279, 52406 52413.