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Volumn 24, Issue 1, 2009, Pages 25-33

Effects of hTERT on genomic instability caused by either metal or radiation or combined exposure

Author keywords

[No Author keywords available]

Indexed keywords

CHROMIUM; COMPLEMENTARY DNA; TELOMERASE REVERSE TRANSCRIPTASE;

EID: 58149109918     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/gen048     Document Type: Article
Times cited : (14)

References (47)
  • 1
    • 0022539516 scopus 로고
    • High yields of lethal mutations in somatic mammalian cells survive ionizing radiation
    • Seymour, C. B., Mothersill, C. and Alper, T. (1986) High yields of lethal mutations in somatic mammalian cells survive ionizing radiation. Int. J. Radiat. Biol., 50, 167-179.
    • (1986) Int. J. Radiat. Biol , vol.50 , pp. 167-179
    • Seymour, C.B.1    Mothersill, C.2    Alper, T.3
  • 3
    • 0030459828 scopus 로고    scopus 로고
    • Persistent expression of morphological abnormalities in the distant progeny of irradiated cells
    • Lyng, F. M., O'Reilly, S., Cottell, D. C., Seymour, C. B. and Mothersill, C. (1996) Persistent expression of morphological abnormalities in the distant progeny of irradiated cells. Radiat. Environ. Biophys., 35, 273-283.
    • (1996) Radiat. Environ. Biophys , vol.35 , pp. 273-283
    • Lyng, F.M.1    O'Reilly, S.2    Cottell, D.C.3    Seymour, C.B.4    Mothersill, C.5
  • 5
    • 0030747838 scopus 로고    scopus 로고
    • Lethal mutations and genomic instability
    • Mothersill, C. and Seymour, C. (1997) Lethal mutations and genomic instability. Int. J. Radiat. Biol., 71, 751-758.
    • (1997) Int. J. Radiat. Biol , vol.71 , pp. 751-758
    • Mothersill, C.1    Seymour, C.2
  • 6
    • 0031673696 scopus 로고    scopus 로고
    • Radiation-induced genomic instability
    • Little, J. B. (1998) Radiation-induced genomic instability. Int. J. Radiat. Biol., 74, 663-671.
    • (1998) Int. J. Radiat. Biol , vol.74 , pp. 663-671
    • Little, J.B.1
  • 7
    • 0034782257 scopus 로고    scopus 로고
    • Heavy metals of relevance to human health induce genomic instability
    • Coen, N., Mothersill, C., Kadhim, M. and Wright, E. G. (2001) Heavy metals of relevance to human health induce genomic instability. J. Pathol., 195, 293-299.
    • (2001) J. Pathol , vol.195 , pp. 293-299
    • Coen, N.1    Mothersill, C.2    Kadhim, M.3    Wright, E.G.4
  • 8
    • 0037463339 scopus 로고    scopus 로고
    • Particulate debris from a titanium metal prosthesis induces genomic instability in primary human fibroblast cells
    • Coen, N., Kadhim, M. A., Wright, E. G., Case, C. P. and Mothersill, C. E. (2003) Particulate debris from a titanium metal prosthesis induces genomic instability in primary human fibroblast cells. Br. J. Cancer, 88, 548-552.
    • (2003) Br. J. Cancer , vol.88 , pp. 548-552
    • Coen, N.1    Kadhim, M.A.2    Wright, E.G.3    Case, C.P.4    Mothersill, C.E.5
  • 9
    • 33745045008 scopus 로고    scopus 로고
    • Effects of hTERT on metal ion-induced genomic instability
    • Glaviano, A., Nayak, V., Cabuy, E. et al. (2006) Effects of hTERT on metal ion-induced genomic instability. Oncogene, 25, 3424-3435.
    • (2006) Oncogene , vol.25 , pp. 3424-3435
    • Glaviano, A.1    Nayak, V.2    Cabuy, E.3
  • 11
    • 0034353521 scopus 로고    scopus 로고
    • The biological effects of combined exposure to low-dose irradiation and heavy metal ions
    • Anan'eva, T. V., Likholat, E. A. and Dvoretskii, A. I. (2000) The biological effects of combined exposure to low-dose irradiation and heavy metal ions. Radiats. Biol. Radioecol., 40, 410-415.
    • (2000) Radiats. Biol. Radioecol , vol.40 , pp. 410-415
    • Anan'eva, T.V.1    Likholat, E.A.2    Dvoretskii, A.I.3
  • 12
    • 0031417905 scopus 로고    scopus 로고
    • Enhancing effect of maternal zinc deficiency and 137Cs gamma-irradiation on the frequency of fetal malformations in mice
    • Hanna, L. A., Peters, J. M., Wiley, L. M., Zidenberg-Cherr, S. and Keen, C. L. (1997) Enhancing effect of maternal zinc deficiency and 137Cs gamma-irradiation on the frequency of fetal malformations in mice. Teratog. Carcinog. Mutagen., 17, 127-137.
    • (1997) Teratog. Carcinog. Mutagen , vol.17 , pp. 127-137
    • Hanna, L.A.1    Peters, J.M.2    Wiley, L.M.3    Zidenberg-Cherr, S.4    Keen, C.L.5
  • 13
    • 0032200912 scopus 로고    scopus 로고
    • Study of combined chronic effects of gamma radiation and lead on the occurrence and repair of DNA injury in mice
    • Chernikov, A. V., Fomenko, L. A., Revina, G. I. and Medvedev, A. I. (1998) Study of combined chronic effects of gamma radiation and lead on the occurrence and repair of DNA injury in mice. Radiats. Biol. Radioecol., 38, 787-792.
    • (1998) Radiats. Biol. Radioecol , vol.38 , pp. 787-792
    • Chernikov, A.V.1    Fomenko, L.A.2    Revina, G.I.3    Medvedev, A.I.4
  • 14
    • 0033646656 scopus 로고    scopus 로고
    • Inhibition of repair of radiation-induced DNA double-strand breaks by nickel and arsenite
    • Takahashi, S., Takeda, E., Kubota, Y. and Okayasu, R. (2000) Inhibition of repair of radiation-induced DNA double-strand breaks by nickel and arsenite. Radiat. Res., 154, 686-691.
    • (2000) Radiat. Res , vol.154 , pp. 686-691
    • Takahashi, S.1    Takeda, E.2    Kubota, Y.3    Okayasu, R.4
  • 15
    • 10744231438 scopus 로고    scopus 로고
    • EWS/ETS fusions activate telomerase in Ewing's tumors
    • Takahashi, A., Higashino, F. and Aoyagi, M. (2003) EWS/ETS fusions activate telomerase in Ewing's tumors. Cancer. Res., 63, 8338-8344.
    • (2003) Cancer. Res , vol.63 , pp. 8338-8344
    • Takahashi, A.1    Higashino, F.2    Aoyagi, M.3
  • 17
    • 0035527263 scopus 로고    scopus 로고
    • Induction of cytogenetic damages by combined action of heavy metal salts, chronic and acute gamma irradiation in bone marrow cells of mice and rats
    • Zaichkina, S. I., Rozanova, O. M., Aptikaeva, G. F., Akmadieva, A. Kh., Klokov, D. Iu. and Smirnova, E. N. (2001) Induction of cytogenetic damages by combined action of heavy metal salts, chronic and acute gamma irradiation in bone marrow cells of mice and rats. Radiats. Biol. Radioecol., 41, 514-518.
    • (2001) Radiats. Biol. Radioecol , vol.41 , pp. 514-518
    • Zaichkina, S.I.1    Rozanova, O.M.2    Aptikaeva, G.F.3    Akmadieva, A.K.4    Klokov, D.I.5    Smirnova, E.N.6
  • 18
    • 0036123697 scopus 로고    scopus 로고
    • Synergistic action of ultraviolet-B radiation and cadmium on the growth of wheat seedlings
    • Shukla, U. C., Joshi, P. C. and Kakkar, P. (2002) Synergistic action of ultraviolet-B radiation and cadmium on the growth of wheat seedlings. Ecotoxicol. Environ. Saf., 51, 90-96.
    • (2002) Ecotoxicol. Environ. Saf , vol.51 , pp. 90-96
    • Shukla, U.C.1    Joshi, P.C.2    Kakkar, P.3
  • 19
    • 0028135452 scopus 로고    scopus 로고
    • Chromosomal instability and alterations of telomeric repeats in irradiated human fibroblasts
    • Sabatier, L., Lebeau, J. and Dutrillaux, B. (2004) Chromosomal instability and alterations of telomeric repeats in irradiated human fibroblasts. Int. J. Radiat. Biol., 66, 611-613.
    • (2004) Int. J. Radiat. Biol , vol.66 , pp. 611-613
    • Sabatier, L.1    Lebeau, J.2    Dutrillaux, B.3
  • 20
    • 0030931491 scopus 로고    scopus 로고
    • Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
    • Blasco, M. A., Lee, H. W., Hande, M. P. et al. (1997) Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell, 91, 25-34.
    • (1997) Cell , vol.91 , pp. 25-34
    • Blasco, M.A.1    Lee, H.W.2    Hande, M.P.3
  • 21
    • 0035839132 scopus 로고    scopus 로고
    • Telomere dysfunction increases mutation rate and genomic instability
    • Hackett, J. A., Feldser, D. M. and Greider, C. W. (2001) Telomere dysfunction increases mutation rate and genomic instability. Cell, 106, 275-286.
    • (2001) Cell , vol.106 , pp. 275-286
    • Hackett, J.A.1    Feldser, D.M.2    Greider, C.W.3
  • 22
    • 0037064127 scopus 로고    scopus 로고
    • Stabilization of telomere length and karyotypic stability are directly correlated with the level of hTERT gene expression in primary fibroblasts
    • Cui, W., Aslam, S., Fletcher, J., Wylie, D., Clinton, M. and Clark, A. J. (2002) Stabilization of telomere length and karyotypic stability are directly correlated with the level of hTERT gene expression in primary fibroblasts. J. Biol. Chem., 277, 38531-38539.
    • (2002) J. Biol. Chem , vol.277 , pp. 38531-38539
    • Cui, W.1    Aslam, S.2    Fletcher, J.3    Wylie, D.4    Clinton, M.5    Clark, A.J.6
  • 23
    • 7644221208 scopus 로고    scopus 로고
    • Radiation-induced bystander effects and adaptive responses - the Yin and Yang of low dose radiobiology?
    • Mothersill, C. and Seymour, C. (2004) Radiation-induced bystander effects and adaptive responses - the Yin and Yang of low dose radiobiology? Mutat. Res., 568, 121-128.
    • (2004) Mutat. Res , vol.568 , pp. 121-128
    • Mothersill, C.1    Seymour, C.2
  • 24
    • 0026694102 scopus 로고
    • Evidence that DNA double-strand breaks initiate the phenotype of delayed reproductive death in Chinese hamster ovary cells
    • Chang, W. P. and Little, J. B. (1992) Evidence that DNA double-strand breaks initiate the phenotype of delayed reproductive death in Chinese hamster ovary cells. Radiat. Res., 131, 53-59.
    • (1992) Radiat. Res , vol.131 , pp. 53-59
    • Chang, W.P.1    Little, J.B.2
  • 25
    • 0037047298 scopus 로고    scopus 로고
    • Reversible manipulation of telomerase expression and telomere length. Implications for the ionizing radiation response and replicative senescence of human cells
    • Rubio, M., Kim, S. and Campisi, J. (2002) Reversible manipulation of telomerase expression and telomere length. Implications for the ionizing radiation response and replicative senescence of human cells. J. Biol. Chem., 277, 28609-28617.
    • (2002) J. Biol. Chem , vol.277 , pp. 28609-28617
    • Rubio, M.1    Kim, S.2    Campisi, J.3
  • 26
    • 84960962997 scopus 로고
    • Action of x-rays on mammalian cells
    • Puck, T. T. and Marcus, P. I. (1956) Action of x-rays on mammalian cells. J. Exp. Med., 103, 653-666.
    • (1956) J. Exp. Med , vol.103 , pp. 653-666
    • Puck, T.T.1    Marcus, P.I.2
  • 27
    • 0021987630 scopus 로고
    • Measurement of micronuclei in lymphocytes
    • Fenech, M. and Morley, A. A. (1985) Measurement of micronuclei in lymphocytes. Mutat. Res., 147, 29-36.
    • (1985) Mutat. Res , vol.147 , pp. 29-36
    • Fenech, M.1    Morley, A.A.2
  • 28
    • 0022203364 scopus 로고
    • Solutions to the kinetic problem in the micronucleus assay
    • Fenech, M. and Morley, A. A. (1985) Solutions to the kinetic problem in the micronucleus assay. Cytobios, 43, 233-246.
    • (1985) Cytobios , vol.43 , pp. 233-246
    • Fenech, M.1    Morley, A.A.2
  • 29
    • 0021923142 scopus 로고
    • The effect of donor age on spontaneous and induced micronuclei
    • Fenech, M. and Morley, A. A. (1985) The effect of donor age on spontaneous and induced micronuclei. Mutat. Res., 148, 99-105.
    • (1985) Mutat. Res , vol.148 , pp. 99-105
    • Fenech, M.1    Morley, A.A.2
  • 31
    • 0031647743 scopus 로고    scopus 로고
    • Expression of delayed toxicity and lethal mutations in the progeny of human cells surviving exposure to radiation and other environmental mutagens
    • Mothersill, C., Crean, M., Lyons, M. et al. (1998) Expression of delayed toxicity and lethal mutations in the progeny of human cells surviving exposure to radiation and other environmental mutagens. Int. J. Radiat. Biol., 74, 673-680.
    • (1998) Int. J. Radiat. Biol , vol.74 , pp. 673-680
    • Mothersill, C.1    Crean, M.2    Lyons, M.3
  • 32
    • 0031697070 scopus 로고    scopus 로고
    • Mechanisms and implications of genomic instability and other delayed effects of ionizing radiation exposure
    • Mothersill, C. and Seymour, C. B. (1998) Mechanisms and implications of genomic instability and other delayed effects of ionizing radiation exposure. Mutagenesis, 13, 421-426.
    • (1998) Mutagenesis , vol.13 , pp. 421-426
    • Mothersill, C.1    Seymour, C.B.2
  • 33
    • 0029047362 scopus 로고
    • A biomarker that identifies senescent human cells in culture and in aging skin in vivo
    • Dimri, G. P., Lee, X., Basile, G. et al. (1995) A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl Acad. Sci. USA, 92, 9363-9367.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 9363-9367
    • Dimri, G.P.1    Lee, X.2    Basile, G.3
  • 34
    • 3042822263 scopus 로고    scopus 로고
    • Telomere length mediates the effects of telomerase on the cellular response to genotoxic stress
    • Rubio, M. A., Davalos, A. R. and Campisi, J. (2004) Telomere length mediates the effects of telomerase on the cellular response to genotoxic stress. Exp. Cell Res., 298, 17-27.
    • (2004) Exp. Cell Res , vol.298 , pp. 17-27
    • Rubio, M.A.1    Davalos, A.R.2    Campisi, J.3
  • 35
    • 10444287596 scopus 로고    scopus 로고
    • Genetic instability and the tumor microenvironment: Towards the concept of microenvironment-induced mutagenesis
    • Bindra, R. S. and Glazer, P. M. (2005) Genetic instability and the tumor microenvironment: towards the concept of microenvironment-induced mutagenesis. Mutat. Res., 569, 75-85.
    • (2005) Mutat. Res , vol.569 , pp. 75-85
    • Bindra, R.S.1    Glazer, P.M.2
  • 36
    • 0242658588 scopus 로고    scopus 로고
    • Genomic instability and bystander effects: A historical perspective
    • Little, J. B. (2003) Genomic instability and bystander effects: a historical perspective. Oncogene, 22, 6978-6987.
    • (2003) Oncogene , vol.22 , pp. 6978-6987
    • Little, J.B.1
  • 37
    • 29244437495 scopus 로고    scopus 로고
    • Telomerase-immortalized human fibroblasts retain UV-induced mutagenesis and p53-mediated DNA damage responses
    • Porter, P. C., Clark, D. R., McDaniel, L. D., McGregor, W. G. and States, J. C. (2006) Telomerase-immortalized human fibroblasts retain UV-induced mutagenesis and p53-mediated DNA damage responses. DNA Repair (Amst.), 5, 61-70.
    • (2006) DNA Repair (Amst.) , vol.5 , pp. 61-70
    • Porter, P.C.1    Clark, D.R.2    McDaniel, L.D.3    McGregor, W.G.4    States, J.C.5
  • 38
    • 17744382360 scopus 로고    scopus 로고
    • Characterization of ataxia telangiectasia fibroblasts with extended life-span through telomerase expression
    • Wood, L. D., Halvorsen, T. L., Dhar, S. et al. (2001) Characterization of ataxia telangiectasia fibroblasts with extended life-span through telomerase expression. Oncogene, 20, 278-288.
    • (2001) Oncogene , vol.20 , pp. 278-288
    • Wood, L.D.1    Halvorsen, T.L.2    Dhar, S.3
  • 39
    • 0034693730 scopus 로고    scopus 로고
    • The in vitro micronucleus technique
    • Fenech, M. (2000) The in vitro micronucleus technique. Mutat. Res., 455, 81-95.
    • (2000) Mutat. Res , vol.455 , pp. 81-95
    • Fenech, M.1
  • 40
    • 0000632574 scopus 로고
    • Irradiation of parts of individual cells
    • Zirkle, R. E. and Bloom, W. (1953) Irradiation of parts of individual cells. Science, 117, 487-493.
    • (1953) Science , vol.117 , pp. 487-493
    • Zirkle, R.E.1    Bloom, W.2
  • 41
    • 0037201935 scopus 로고    scopus 로고
    • Cytotoxicity and oxidative mechanisms of different forms of chromium
    • Bagchi, D., Stohs, S. J., Downs, B. W., Bagchi, M. and Preuss, H. G. (2002) Cytotoxicity and oxidative mechanisms of different forms of chromium. Toxicology, 180, 5-22.
    • (2002) Toxicology , vol.180 , pp. 5-22
    • Bagchi, D.1    Stohs, S.J.2    Downs, B.W.3    Bagchi, M.4    Preuss, H.G.5
  • 42
    • 18244387491 scopus 로고    scopus 로고
    • Frequent microsatellite instability in lung cancer from chromate-exposed workers
    • Hirose, T., Kondo, K., Takahashi, Y. et al. (2002) Frequent microsatellite instability in lung cancer from chromate-exposed workers. Mol. Carcinog., 33, 172-180.
    • (2002) Mol. Carcinog , vol.33 , pp. 172-180
    • Hirose, T.1    Kondo, K.2    Takahashi, Y.3
  • 43
    • 0037182120 scopus 로고    scopus 로고
    • The cytotoxicity and genotoxicity of particulate and soluble hexavalent chromium in human lung cells
    • Wise, J. P., Sr, Wise, S. S. and Little, J. E. (2002) The cytotoxicity and genotoxicity of particulate and soluble hexavalent chromium in human lung cells. Mutat. Res., 517, 221-229.
    • (2002) Mutat. Res , vol.517 , pp. 221-229
    • Wise Sr, J.P.1    Wise, S.S.2    Little, J.E.3
  • 44
    • 35148832010 scopus 로고    scopus 로고
    • Chromium crosslinks histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation
    • Schnekenburger, M., Talaska, G. and Puga, A. (2007) Chromium crosslinks histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation. Mol. Cell. Biol., 27, 7089-7101.
    • (2007) Mol. Cell. Biol , vol.27 , pp. 7089-7101
    • Schnekenburger, M.1    Talaska, G.2    Puga, A.3
  • 46
    • 0023177935 scopus 로고
    • Risk to preimplantation mouse embryos of combinations of heavy metals and radiation
    • Muller, W. U. and Streffer, C. (1987) Risk to preimplantation mouse embryos of combinations of heavy metals and radiation. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med., 51, 997-1006.
    • (1987) Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med , vol.51 , pp. 997-1006
    • Muller, W.U.1    Streffer, C.2
  • 47
    • 0024794198 scopus 로고
    • Effects of nickel sulfate, lead sulfate, and sodium arsenite alone and with UV light on sister chromatid exchanges in cultured human lymphocytes
    • Sahu, R. K., Katsifis, S. P., Kinney, P. L. and Christie, N. T. (1989) Effects of nickel sulfate, lead sulfate, and sodium arsenite alone and with UV light on sister chromatid exchanges in cultured human lymphocytes. Mol. Toxicol., 2, 129-136.
    • (1989) Mol. Toxicol , vol.2 , pp. 129-136
    • Sahu, R.K.1    Katsifis, S.P.2    Kinney, P.L.3    Christie, N.T.4


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