Persistent expression of morphological abnormalities in the distant progeny of irradiated cells

Radiation and Environmental Biophysics

Volumn 35, Issue 4, 1996, Pages 273-283

  Lyng, Fiona M ^a   O'Reilly, Sandra ^a   Cottell, David C ^b   Seymour, Colin B ^a   Mothersill, Carmel ^a  

^a DUBLIN INSTITUTE OF TECHNOLOGY   (Ireland)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DIVISION; HUMAN; HUMAN CELL; IRRADIATION; LETHAL MUTANT; NONHUMAN; PROGENY; RADIATION EXPOSURE; RADIATION HAZARD; RADIATION INJURY;

ANIMALS; APOPTOSIS; CELL SURVIVAL; CHO CELLS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, RADIATION;

EID: 0030459828     PISSN: 0301634X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004110050040     Document Type: Article

References (38)

1. Seymour CB, Mothersill C, Alper T (1986) High yields of lethal mutations in somatic mammalian cells that survive ionising radiation. Int J Radiat Biol 53:319-330
2. Alper T, Mothersill C, Seymour CB (1988) Lethal mutations attributable to misrepair of Q lesions. Int J Radiat Biol 54:525-530
3. Mendonca MS, Kurohara W, Antoniono RJ, Redpath JL (1989) Plating efficiency as a function of time post-irradiation. Evidence for the delayed expression of lethal mutations. Radiat Res 119:387-393
4. Chang WP, Little JB (1991) Delayed reproductive death in X-irradiated Chinese hamster ovary cells. Int. J Radiat Biol 60: 483-496
5. Chang WP, Little JB (1992) Delayed reproductive death as a dominant phenotype in cell clones surviving x-irradiation. Carcinogenesis 13:923-928
6. Kadhim MA, Macdonald DA, Goodhead DT, Lorimore SA, Marsden SJ, Wright EG (1992) Transmission of chromosomal instability after plutonium alpha particle irradiation. Nature 355: 738-740
7. Seymour CB, Mothersill C (1992) All colonies of CHO-KI cells surviving g radiation contain non-viable cells. Mutat Res 267: 19-30
8. O'Reilly S, Mothersill C, Seymour CB (1994) Radiation induced lethal mutations occur at a constant rate in an immortalised human keratinocyte cell line. Int J Radiat Biol 66:77-83
9. Arends MJ, Harrison DJ (1994) Apoptosis: molecular aspects and pathological perspective. In: Crocker J (ed) Molecular biology in histopathology. Wiley & Sons, Chichester, pp 151-170
10. Puck TT, Marcus PI (1956) Action of X-rays on mammalian cells. J Exp Med 103:653-666
11. Brown DC, Trott KR (1994) Clonal heterogeneity in the progeny of HeLa cells which survive X-irradiation. Int J Radiat Biol 66:151-156
12. Marder BA, Morgan WF (1993) Delayed chromosomal instability induced by DNA damage. Mol Cell Biol 13: 6667-6677
13. Barham SS, Walters RA (1978) X-irradiation induced nuclear lesions in cultured mammalian cells: an ultrastructural analysis. Radiat. Res. 76:105-126
14. Montgomery PO'B, Karney D, Reynolds RC, McClendon D (1964) Cellular and subcellular effects of ionizing radiations. Am. J Pathol. 44:727-746
15. Hugon J, Borgers M (1968) Fine structure of the nuclei of the duodenal crypt cells after X-irradiation. Am J Pathol 52: 701-723
16. Szekely JG, Raaphorst GP, Lobreau AU, Copps TP (1982) Effect of X-irradiation and radiation modifiers on cellular ultrastructure. Scanning Electron Microsc I:335-347
17. Somosy Z, Pikli A, Kubasova T, Koteles GJ, Bodo M (1985) Alteration of nuclear diameter of murine lymphocytes upon the effects of X-irradiation in vivo. Radiobiol. Radiother. 26 (H3): 305-310
18. Gasperin P, Gozy M, Pauwels O, Fruhling J, Van-Houtte P, Pasteels JL, Kiss R (1992) Monitoring of radiotherapy-induced morphonuclear modifications in the MXT mouse mammary carcinoma by means of digital cell image analysis. Int J Radiat Oncol Biol Phys 22:979-987
19. Isaacs JT (1993) Role of programmed cell death in carcinogenesis. Environ Health Perspect 101:27-34
20. Borek C, Fenoglio CM (1976) Scanning electron microscopy of surface features of hamster embryo cells transformed in vitro by X-irradiation. Cancer Res 36:1325-1334
21. Glaser R, Mumaw V, Farrugia R, Munger B (1977) Scanning electron microscopy of the surfaces of hamster embryo cells transformed by herpes simplex virus. Cancer Res 37:4420-4422
22. Beug H, Claviez M, Jokusch BM, Graf T (1978) Differential expression of Rous sarcoma virus specific transformation parameters in enucleated cells. Cell 14:843-856
23. Saxholm HJK, Reith A (1979) The surface structure of 7,12-dimethylbenz(a)anthracene transformed C3H 10T1/2 cells. A quantitative scanning electron microscopical study. Eur J Cancer 15:843-855
24. Reith A, Puntervold R, Saxholm HJK (1980) A quantitative scanning electron microscopic study of microvilli in interphase and mitosis of carcinogen transformed fibroblasts. Scanning Electron Microsc III:23-28
25. Garnett HM (1979) Early alterations in the morphology of cytomegalovirus-infected human fibroblasts. Intervirology 11: 359-362
26. Murti KG, Goorha R (1983) Interaction of frog virus 3 with the cytoskeleton. I. Altered organisation of microtubules, intermediate filaments and microfilaments. J Cell Biol 96:1248-1257
27. Krempien U, Jockusch BM, Jungwirth W (1984) Herpes simplex virus induced cell surface protrusions. Intervirology 22: 156-163
28. Ambrose EJ, Easty DM (1970) Cell biology. Nelson. London
29. Knutton S, Sumner MCB, Pasternak CA (1975) Role of microvilli in surface changes of synchronised P815Y mastocytoma cells. J Cell Biol 66:568-576
30. Ericsson CA, Trinkaus JP (1976) Microvilli and blebs as sources of reserve surface membrane during cell spreading. Exp Cell Res 99:375-384
31. Cilliers GD, Lochner A (1993) Radiation induced damage of the Wistar rat heart biochemistry and functions. Radiother Oncol 27:216-222
32. Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, Korsmeyer SJ (1993) Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75:241-251
33. Ratan RR, Murphy TH, Baraban JM (1994) Oxidative stress induces apoptosis in embryonic cortical neurons. J Neurochem 62: 376-379
34. Chattergee J, Jonas Y, Hodgekiss RG (1995) Persistently reduced survival of cells plated at various post irradiation time points from mice exposed in vivo to fractionated radiotherapy. Acta Oncol 34:493-498
35. Kao C, Wu SQ, DeVries S, Reznikoff WS, Waldman FM, Reznikoff CA (1993) Carcinogen-induced amplification of SV40 DNA inserted at 9q12-21.1 associated with chromosome breakage, deletions, and translocations in human uroepithelial cell transformation in vitro. Genes Chromosomes Cancer 8:155-166
36. Honma M, Mizusawa H, Sasaki K, Hayashi M, Ohno T, Tanaka N, Sofuni T (1994) Demonstration by DNA fingerprint analysis of genomic instability in mouse BALB 3T3 cells during cell transformation. Mutat Res 304:167-179
37. Paquete B, Little JB (1994) In vivo enhancement of genomic instability in minisatellite sequences of mouse C3H/10T1/2 cells transformed in vitro by X-rays. Cancer Res 54:3173-3178
38. Herrera LA, Santiago P, Rojas G, Salazar PM, Tato P, Molinari JL, Schiffmann D, Ostrosky-Wegman P (1994) Immune response impairment, genotoxicity and morphological transformation induced by Taenia solium metacestode. Mutat Res 305: 223-228