-
1
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003 299 : 1057 61.
-
(2003)
Science
, vol.299
, pp. 1057-61
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
2
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995 155 : 1151 64.
-
(1995)
J Immunol
, vol.155
, pp. 1151-64
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
3
-
-
0346103659
-
Diversity of regulatory CD4+T cells controlling distinct organ-specific autoimmune diseases
-
Alyanakian MA, You S, Damotte D, Gouarin C, Esling A, Garcia C, et al. Diversity of regulatory CD4+T cells controlling distinct organ-specific autoimmune diseases. Proc Natl Acad Sci USA 2003 100 : 15806 11.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15806-11
-
-
Alyanakian, M.A.1
You, S.2
Damotte, D.3
Gouarin, C.4
Esling, A.5
Garcia, C.6
-
4
-
-
25444510061
-
Control of type 1 autoimmune diabetes by naturally occurring CD4+ CD25+ regulatory T lymphocytes in neonatal NOD mice
-
Piccirillo CA, Tritt M, Sgouroudis E, Albanese A, Pyzik M, Hay V. Control of type 1 autoimmune diabetes by naturally occurring CD4+ CD25+ regulatory T lymphocytes in neonatal NOD mice. Ann N Y Acad Sci 2005 1051 : 72 87.
-
(2005)
Ann N Y Acad Sci
, vol.1051
, pp. 72-87
-
-
Piccirillo, C.A.1
Tritt, M.2
Sgouroudis, E.3
Albanese, A.4
Pyzik, M.5
Hay, V.6
-
5
-
-
2942692039
-
CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes
-
Tarbell KV, Yamazaki S, Olson K, Toy P, Steinman RM. CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J Exp Med 2004 199 : 1467 77.
-
(2004)
J Exp Med
, vol.199
, pp. 1467-77
-
-
Tarbell, K.V.1
Yamazaki, S.2
Olson, K.3
Toy, P.4
Steinman, R.M.5
-
6
-
-
0036141438
-
Multiple immuno-regulatory defects in type-1 diabetes
-
Kukreja A, Cost G, Marker J, Zhang C, Sun Z, Lin-Su K, et al. Multiple immuno-regulatory defects in type-1 diabetes. J Clin Invest 2002 109 : 131 40.
-
(2002)
J Clin Invest
, vol.109
, pp. 131-40
-
-
Kukreja, A.1
Cost, G.2
Marker, J.3
Zhang, C.4
Sun, Z.5
Lin-Su, K.6
-
7
-
-
17844364504
-
Functional defects and the influence of age on the frequency of CD4+CD25+ T-cells in type 1 diabetes
-
Brusko TM, Wasserfall CH, Clare-Salzler MJ, Schatz DA, Atkinson MA. Functional defects and the influence of age on the frequency of CD4+CD25+ T-cells in type 1 diabetes. Diabetes 2005 54 : 1407 14.
-
(2005)
Diabetes
, vol.54
, pp. 1407-14
-
-
Brusko, T.M.1
Wasserfall, C.H.2
Clare-Salzler, M.J.3
Schatz, D.A.4
Atkinson, M.A.5
-
8
-
-
12144249838
-
Defective suppressor function in CD4+CD25+ T-cells from patients with type 1 diabetes
-
Lindley S, Dayan CM, Bishop A, Roep BO, Peakman M, Tree TI. Defective suppressor function in CD4+CD25+ T-cells from patients with type 1 diabetes. Diabetes 2005 54 : 92 9.
-
(2005)
Diabetes
, vol.54
, pp. 92-9
-
-
Lindley, S.1
Dayan, C.M.2
Bishop, A.3
Roep, B.O.4
Peakman, M.5
Tree, T.I.6
-
10
-
-
33748745463
-
Phenotypic and genetic analyses of T-cell-mediated immunoregulation in patients with Type 1 diabetes
-
Tsutsumi Y, Jie X, Ihara K, Nomura A, Kanemitsu S, Takada H, et al. Phenotypic and genetic analyses of T-cell-mediated immunoregulation in patients with Type 1 diabetes. Diabet Med 2006 23 : 1145 50.
-
(2006)
Diabet Med
, vol.23
, pp. 1145-50
-
-
Tsutsumi, Y.1
Jie, X.2
Ihara, K.3
Nomura, A.4
Kanemitsu, S.5
Takada, H.6
-
11
-
-
33847373481
-
No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes
-
Brusko T, Wasserfall C, McGrail K, Schatz R, Viener HL, Schatz D, et al. No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes. Diabetes 2007 56 : 604 12.
-
(2007)
Diabetes
, vol.56
, pp. 604-12
-
-
Brusko, T.1
Wasserfall, C.2
McGrail, K.3
Schatz, R.4
Viener, H.L.5
Schatz, D.6
-
12
-
-
33745817085
-
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
-
Liu W, Putnam AL, Xu-yu Z, Szot GL, Lee MR, Zhu S, et al. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med 2006 203 : 1701 11.
-
(2006)
J Exp Med
, vol.203
, pp. 1701-11
-
-
Liu, W.1
Putnam, A.L.2
Xu-Yu, Z.3
Szot, G.L.4
Lee, M.R.5
Zhu, S.6
-
13
-
-
33845691031
-
A mini meta-analysis of studies on CD4+CD25+ T cells in human type 1 diabetes: Report of the Immunology of Diabetes Society T Cell Workshop
-
Tree TI, Roep BO, Peakman M. A mini meta-analysis of studies on CD4+CD25+ T cells in human type 1 diabetes: report of the Immunology of Diabetes Society T Cell Workshop. Ann N Y Acad Sci 2006 1079 : 9 18.
-
(2006)
Ann N Y Acad Sci
, vol.1079
, pp. 9-18
-
-
Tree, T.I.1
Roep, B.O.2
Peakman, M.3
-
14
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003 4 : 330 6.
-
(2003)
Nat Immunol
, vol.4
, pp. 330-6
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
15
-
-
15244354286
-
Regulatory T cell lineage specification by the forkhead transcription factor foxp3
-
Fontenot JD, Rasmussen JP, Williams LM, Dooley JL, Farr AG, Rudensky AY. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity 2005 22 : 329 41.
-
(2005)
Immunity
, vol.22
, pp. 329-41
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Williams, L.M.3
Dooley, J.L.4
Farr, A.G.5
Rudensky, A.Y.6
-
16
-
-
8344275995
-
Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells
-
Yagi H, Nomura T, Nakamura K, Yamazaki S, Kitawaki T, Hori S, et al. Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells. Int Immunol 2004 16 : 1643 56.
-
(2004)
Int Immunol
, vol.16
, pp. 1643-56
-
-
Yagi, H.1
Nomura, T.2
Nakamura, K.3
Yamazaki, S.4
Kitawaki, T.5
Hori, S.6
-
17
-
-
19944369378
-
Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans
-
Morgan ME, van Bilsen JH, Bakker AM, Heemskerk B, Schilham MW, Hartgers FC, et al. Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans. Hum Immunol 2005 66 : 13 20.
-
(2005)
Hum Immunol
, vol.66
, pp. 13-20
-
-
Morgan, M.E.1
Van Bilsen, J.H.2
Bakker, A.M.3
Heemskerk, B.4
Schilham, M.W.5
Hartgers, F.C.6
-
18
-
-
33947121146
-
Transient regulatory T-cells: A state attained by all activated human T-cells
-
Pillai V, Ortega SB, Wang CK, Karandikar NJ. Transient regulatory T-cells: a state attained by all activated human T-cells. Clin Immunol 2006 123 : 18 29.
-
(2006)
Clin Immunol
, vol.123
, pp. 18-29
-
-
Pillai, V.1
Ortega, S.B.2
Wang, C.K.3
Karandikar, N.J.4
-
19
-
-
33846375082
-
Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells
-
Wang J, Ioan-Facsinay A, van der Voort EI, Huizinga TW, Toes RE. Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells. Eur J Immunol 2006 37 : 129 38.
-
(2006)
Eur J Immunol
, vol.37
, pp. 129-38
-
-
Wang, J.1
Ioan-Facsinay, A.2
Van Der Voort, E.I.3
Huizinga, T.W.4
Toes, R.E.5
-
20
-
-
33751231701
-
FOXP3+ regulatory T cells: Current controversies and future perspectives
-
Banham AH, Powrie FM, Suri-Payer E. FOXP3+ regulatory T cells: current controversies and future perspectives. Eur J Immunol 2006 36 : 2832 6.
-
(2006)
Eur J Immunol
, vol.36
, pp. 2832-6
-
-
Banham, A.H.1
Powrie, F.M.2
Suri-Payer, E.3
-
21
-
-
27644449311
-
The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs
-
Allan SE, Passerini L, Bacchetta R, Crellin N, Dai M, Orban PC, et al. The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs. J Clin Invest 2005 115 : 3276 84.
-
(2005)
J Clin Invest
, vol.115
, pp. 3276-84
-
-
Allan, S.E.1
Passerini, L.2
Bacchetta, R.3
Crellin, N.4
Dai, M.5
Orban, P.C.6
-
22
-
-
33748751458
-
Splice variants of human FOXP3 are functional inhibitors of human CD4+ T-cell activation
-
Smith EL, Finney HM, Nesbitt AM, Ramsdell F, Robinson MK. Splice variants of human FOXP3 are functional inhibitors of human CD4+ T-cell activation. Immunology 2006 119 : 203 11.
-
(2006)
Immunology
, vol.119
, pp. 203-11
-
-
Smith, E.L.1
Finney, H.M.2
Nesbitt, A.M.3
Ramsdell, F.4
Robinson, M.K.5
-
23
-
-
33745813929
-
Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
-
Seddiki N, Santner-Nanan B, Martinson J, Zaunders J, Sasson S, Landay A, et al. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med 2006 203 : 1693 700.
-
(2006)
J Exp Med
, vol.203
, pp. 1693-700
-
-
Seddiki, N.1
Santner-Nanan, B.2
Martinson, J.3
Zaunders, J.4
Sasson, S.5
Landay, A.6
-
24
-
-
33847415066
-
Natural regulatory T cells: Mechanisms of suppression
-
Miyara M, Sakaguchi S. Natural regulatory T cells: mechanisms of suppression. Trends Mol Med 2007 13 : 108 16.
-
(2007)
Trends Mol Med
, vol.13
, pp. 108-16
-
-
Miyara, M.1
Sakaguchi, S.2
-
25
-
-
15444363794
-
T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells
-
Fahlen L, Read S, Gorelik L, Hurst SD, Coffman RL, Flavell RA, et al. T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells. J Exp Med 2005 201 : 737 46.
-
(2005)
J Exp Med
, vol.201
, pp. 737-46
-
-
Fahlen, L.1
Read, S.2
Gorelik, L.3
Hurst, S.D.4
Coffman, R.L.5
Flavell, R.A.6
-
26
-
-
17144400393
-
TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells
-
Marie JC, Letterio JJ, Gavin M, Rudensky AY. TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells. J Exp Med 2005 201 : 1061 7.
-
(2005)
J Exp Med
, vol.201
, pp. 1061-7
-
-
Marie, J.C.1
Letterio, J.J.2
Gavin, M.3
Rudensky, A.Y.4
-
27
-
-
1642577126
-
TGF-beta1 plays an important role in the mechanism of CD4+ CD25+ regulatory T cell activity in both humans and mice
-
Nakamura K, Kitani A, Fuss I, Pedersen A, Harada N, Nawata H, et al. TGF-beta1 plays an important role in the mechanism of CD4+ CD25+ regulatory T cell activity in both humans and mice. J Immunol 2004 172 : 834 42.
-
(2004)
J Immunol
, vol.172
, pp. 834-42
-
-
Nakamura, K.1
Kitani, A.2
Fuss, I.3
Pedersen, A.4
Harada, N.5
Nawata, H.6
-
28
-
-
35548992776
-
Insulin VNTR I/III genotype is associated with autoantibodies against glutamic acid decarboxylase in newly diagnosed type 1 diabetes
-
Rajasalu T, Haller K, Salur L, Kisand K, Tillmann V, Schlosser M, et al. Insulin VNTR I/III genotype is associated with autoantibodies against glutamic acid decarboxylase in newly diagnosed type 1 diabetes. Diabetes Metab Res Rev 2007 23 : 567 71.
-
(2007)
Diabetes Metab Res Rev
, vol.23
, pp. 567-71
-
-
Rajasalu, T.1
Haller, K.2
Salur, L.3
Kisand, K.4
Tillmann, V.5
Schlosser, M.6
-
31
-
-
33747801470
-
IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo
-
Zorn E, Nelson EA, Mohseni M, Porcheray F, Kim H, Litsa D, et al. IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo. Blood 2006 108 : 1571 9.
-
(2006)
Blood
, vol.108
, pp. 1571-9
-
-
Zorn, E.1
Nelson, E.A.2
Mohseni, M.3
Porcheray, F.4
Kim, H.5
Litsa, D.6
-
32
-
-
36048978911
-
Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature
-
Hill JA, Feuerer M, Tash K, Haxhinasto S, Perez J, Melamed R, et al. Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature. Immunity 2007 27 : 786 800.
-
(2007)
Immunity
, vol.27
, pp. 786-800
-
-
Hill, J.A.1
Feuerer, M.2
Tash, K.3
Haxhinasto, S.4
Perez, J.5
Melamed, R.6
-
33
-
-
33847125247
-
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
-
Wan YY, Flavell RA. Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature 2007 445 : 766 70.
-
(2007)
Nature
, vol.445
, pp. 766-70
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
34
-
-
37149003363
-
Compromised CD4+CD25high regulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level
-
Venken K, Hellings N, Thewissen M, Somers V, Hensen K, Rummens JL, et al. Compromised CD4+CD25high regulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level. Immunology 2008 123 : 79 89.
-
(2008)
Immunology
, vol.123
, pp. 79-89
-
-
Venken, K.1
Hellings, N.2
Thewissen, M.3
Somers, V.4
Hensen, K.5
Rummens, J.L.6
-
35
-
-
34848858303
-
Enhanced efficacy of regulatory T cell transfer against increasing resistance, by elevated Foxp3 expression induced in arthritic murine hosts
-
Ohata J, Miura T, Johnson TA, Hori S, Ziegler SF, Kohsaka H. Enhanced efficacy of regulatory T cell transfer against increasing resistance, by elevated Foxp3 expression induced in arthritic murine hosts. Arthritis Rheum 2007 56 : 2947 56.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 2947-56
-
-
Ohata, J.1
Miura, T.2
Johnson, T.A.3
Hori, S.4
Ziegler, S.F.5
Kohsaka, H.6
-
36
-
-
0347990607
-
Transmission of maternal islet antibodies and risk of autoimmune diabetes in offspring of mothers with type 1 diabetes
-
Koczwara K, Bonifacio E, Ziegler AG. Transmission of maternal islet antibodies and risk of autoimmune diabetes in offspring of mothers with type 1 diabetes. Diabetes 2004 53 : 1 4.
-
(2004)
Diabetes
, vol.53
, pp. 1-4
-
-
Koczwara, K.1
Bonifacio, E.2
Ziegler, A.G.3
-
37
-
-
33750874347
-
Evidence for immunological priming and increased frequency of CD4+CD25+ cord blood T cells in children born to mothers with type 1 diabetes
-
Holm BC, Svensson J, Åkesson C, Arvastsson J, Ljungberg J, Lynch K, et al. Evidence for immunological priming and increased frequency of CD4+CD25+ cord blood T cells in children born to mothers with type 1 diabetes. Clin Exp Immunol 2006 146 : 493 502.
-
(2006)
Clin Exp Immunol
, vol.146
, pp. 493-502
-
-
Holm, B.C.1
Svensson, J.2
Åkesson, C.3
Arvastsson, J.4
Ljungberg, J.5
Lynch, K.6
-
38
-
-
17744398406
-
Prognostic factors for the course of beta cell function in autoimmune diabetes
-
Törn C, Landin-Olsson M, Lernmark Å, Palmer JP, Arnqvist HJ, Blohme G, et al. Prognostic factors for the course of beta cell function in autoimmune diabetes. J Clin Endocrinol Metab 2000 85 : 4619 23.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 4619-23
-
-
Törn, C.1
Landin-Olsson, M.2
Å, L.3
Palmer, J.P.4
Arnqvist, H.J.5
Blohme, G.6
|