메뉴 건너뛰기




Volumn 116, Issue 10, 2008, Pages 896-902

Higher FoxP3 mRNA expression in peripheral blood mononuclear cells of GAD65 or IA-2 autoantibody-positive compared with autoantibody-negative persons

Author keywords

Autoantibodies; FoxP3; Regulatory T cell; Type 1 diabetes

Indexed keywords

AUTOANTIBODY; GLUTAMATE DECARBOXYLASE 65 ANTIBODY; ISOPROTEIN; MESSENGER RNA; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TYROSINE PHOSPHATASE LIKE INSULINOMA ANTIGEN 2 AUTOANTIBODY; UNCLASSIFIED DRUG;

EID: 58149094519     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/j.1600-0463.2008.00889.x     Document Type: Article
Times cited : (9)

References (38)
  • 1
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003 299 : 1057 61.
    • (2003) Science , vol.299 , pp. 1057-61
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 2
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995 155 : 1151 64.
    • (1995) J Immunol , vol.155 , pp. 1151-64
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 3
    • 0346103659 scopus 로고    scopus 로고
    • Diversity of regulatory CD4+T cells controlling distinct organ-specific autoimmune diseases
    • Alyanakian MA, You S, Damotte D, Gouarin C, Esling A, Garcia C, et al. Diversity of regulatory CD4+T cells controlling distinct organ-specific autoimmune diseases. Proc Natl Acad Sci USA 2003 100 : 15806 11.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 15806-11
    • Alyanakian, M.A.1    You, S.2    Damotte, D.3    Gouarin, C.4    Esling, A.5    Garcia, C.6
  • 4
    • 25444510061 scopus 로고    scopus 로고
    • Control of type 1 autoimmune diabetes by naturally occurring CD4+ CD25+ regulatory T lymphocytes in neonatal NOD mice
    • Piccirillo CA, Tritt M, Sgouroudis E, Albanese A, Pyzik M, Hay V. Control of type 1 autoimmune diabetes by naturally occurring CD4+ CD25+ regulatory T lymphocytes in neonatal NOD mice. Ann N Y Acad Sci 2005 1051 : 72 87.
    • (2005) Ann N Y Acad Sci , vol.1051 , pp. 72-87
    • Piccirillo, C.A.1    Tritt, M.2    Sgouroudis, E.3    Albanese, A.4    Pyzik, M.5    Hay, V.6
  • 5
    • 2942692039 scopus 로고    scopus 로고
    • CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes
    • Tarbell KV, Yamazaki S, Olson K, Toy P, Steinman RM. CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J Exp Med 2004 199 : 1467 77.
    • (2004) J Exp Med , vol.199 , pp. 1467-77
    • Tarbell, K.V.1    Yamazaki, S.2    Olson, K.3    Toy, P.4    Steinman, R.M.5
  • 7
    • 17844364504 scopus 로고    scopus 로고
    • Functional defects and the influence of age on the frequency of CD4+CD25+ T-cells in type 1 diabetes
    • Brusko TM, Wasserfall CH, Clare-Salzler MJ, Schatz DA, Atkinson MA. Functional defects and the influence of age on the frequency of CD4+CD25+ T-cells in type 1 diabetes. Diabetes 2005 54 : 1407 14.
    • (2005) Diabetes , vol.54 , pp. 1407-14
    • Brusko, T.M.1    Wasserfall, C.H.2    Clare-Salzler, M.J.3    Schatz, D.A.4    Atkinson, M.A.5
  • 8
    • 12144249838 scopus 로고    scopus 로고
    • Defective suppressor function in CD4+CD25+ T-cells from patients with type 1 diabetes
    • Lindley S, Dayan CM, Bishop A, Roep BO, Peakman M, Tree TI. Defective suppressor function in CD4+CD25+ T-cells from patients with type 1 diabetes. Diabetes 2005 54 : 92 9.
    • (2005) Diabetes , vol.54 , pp. 92-9
    • Lindley, S.1    Dayan, C.M.2    Bishop, A.3    Roep, B.O.4    Peakman, M.5    Tree, T.I.6
  • 9
    • 13944270218 scopus 로고    scopus 로고
    • CD4+CD25high regulatory T cells in human autoimmune diabetes
    • Putnam AL, Vendrame F, Dotta F, Gottlieb PA. CD4+CD25high regulatory T cells in human autoimmune diabetes. J Autoimmun 2005 24 : 55 62.
    • (2005) J Autoimmun , vol.24 , pp. 55-62
    • Putnam, A.L.1    Vendrame, F.2    Dotta, F.3    Gottlieb, P.A.4
  • 10
    • 33748745463 scopus 로고    scopus 로고
    • Phenotypic and genetic analyses of T-cell-mediated immunoregulation in patients with Type 1 diabetes
    • Tsutsumi Y, Jie X, Ihara K, Nomura A, Kanemitsu S, Takada H, et al. Phenotypic and genetic analyses of T-cell-mediated immunoregulation in patients with Type 1 diabetes. Diabet Med 2006 23 : 1145 50.
    • (2006) Diabet Med , vol.23 , pp. 1145-50
    • Tsutsumi, Y.1    Jie, X.2    Ihara, K.3    Nomura, A.4    Kanemitsu, S.5    Takada, H.6
  • 11
    • 33847373481 scopus 로고    scopus 로고
    • No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes
    • Brusko T, Wasserfall C, McGrail K, Schatz R, Viener HL, Schatz D, et al. No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes. Diabetes 2007 56 : 604 12.
    • (2007) Diabetes , vol.56 , pp. 604-12
    • Brusko, T.1    Wasserfall, C.2    McGrail, K.3    Schatz, R.4    Viener, H.L.5    Schatz, D.6
  • 12
    • 33745817085 scopus 로고    scopus 로고
    • CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
    • Liu W, Putnam AL, Xu-yu Z, Szot GL, Lee MR, Zhu S, et al. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med 2006 203 : 1701 11.
    • (2006) J Exp Med , vol.203 , pp. 1701-11
    • Liu, W.1    Putnam, A.L.2    Xu-Yu, Z.3    Szot, G.L.4    Lee, M.R.5    Zhu, S.6
  • 13
    • 33845691031 scopus 로고    scopus 로고
    • A mini meta-analysis of studies on CD4+CD25+ T cells in human type 1 diabetes: Report of the Immunology of Diabetes Society T Cell Workshop
    • Tree TI, Roep BO, Peakman M. A mini meta-analysis of studies on CD4+CD25+ T cells in human type 1 diabetes: report of the Immunology of Diabetes Society T Cell Workshop. Ann N Y Acad Sci 2006 1079 : 9 18.
    • (2006) Ann N Y Acad Sci , vol.1079 , pp. 9-18
    • Tree, T.I.1    Roep, B.O.2    Peakman, M.3
  • 14
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003 4 : 330 6.
    • (2003) Nat Immunol , vol.4 , pp. 330-6
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 16
    • 8344275995 scopus 로고    scopus 로고
    • Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells
    • Yagi H, Nomura T, Nakamura K, Yamazaki S, Kitawaki T, Hori S, et al. Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells. Int Immunol 2004 16 : 1643 56.
    • (2004) Int Immunol , vol.16 , pp. 1643-56
    • Yagi, H.1    Nomura, T.2    Nakamura, K.3    Yamazaki, S.4    Kitawaki, T.5    Hori, S.6
  • 18
    • 33947121146 scopus 로고    scopus 로고
    • Transient regulatory T-cells: A state attained by all activated human T-cells
    • Pillai V, Ortega SB, Wang CK, Karandikar NJ. Transient regulatory T-cells: a state attained by all activated human T-cells. Clin Immunol 2006 123 : 18 29.
    • (2006) Clin Immunol , vol.123 , pp. 18-29
    • Pillai, V.1    Ortega, S.B.2    Wang, C.K.3    Karandikar, N.J.4
  • 20
    • 33751231701 scopus 로고    scopus 로고
    • FOXP3+ regulatory T cells: Current controversies and future perspectives
    • Banham AH, Powrie FM, Suri-Payer E. FOXP3+ regulatory T cells: current controversies and future perspectives. Eur J Immunol 2006 36 : 2832 6.
    • (2006) Eur J Immunol , vol.36 , pp. 2832-6
    • Banham, A.H.1    Powrie, F.M.2    Suri-Payer, E.3
  • 22
    • 33748751458 scopus 로고    scopus 로고
    • Splice variants of human FOXP3 are functional inhibitors of human CD4+ T-cell activation
    • Smith EL, Finney HM, Nesbitt AM, Ramsdell F, Robinson MK. Splice variants of human FOXP3 are functional inhibitors of human CD4+ T-cell activation. Immunology 2006 119 : 203 11.
    • (2006) Immunology , vol.119 , pp. 203-11
    • Smith, E.L.1    Finney, H.M.2    Nesbitt, A.M.3    Ramsdell, F.4    Robinson, M.K.5
  • 23
    • 33745813929 scopus 로고    scopus 로고
    • Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
    • Seddiki N, Santner-Nanan B, Martinson J, Zaunders J, Sasson S, Landay A, et al. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med 2006 203 : 1693 700.
    • (2006) J Exp Med , vol.203 , pp. 1693-700
    • Seddiki, N.1    Santner-Nanan, B.2    Martinson, J.3    Zaunders, J.4    Sasson, S.5    Landay, A.6
  • 24
    • 33847415066 scopus 로고    scopus 로고
    • Natural regulatory T cells: Mechanisms of suppression
    • Miyara M, Sakaguchi S. Natural regulatory T cells: mechanisms of suppression. Trends Mol Med 2007 13 : 108 16.
    • (2007) Trends Mol Med , vol.13 , pp. 108-16
    • Miyara, M.1    Sakaguchi, S.2
  • 25
    • 15444363794 scopus 로고    scopus 로고
    • T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells
    • Fahlen L, Read S, Gorelik L, Hurst SD, Coffman RL, Flavell RA, et al. T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells. J Exp Med 2005 201 : 737 46.
    • (2005) J Exp Med , vol.201 , pp. 737-46
    • Fahlen, L.1    Read, S.2    Gorelik, L.3    Hurst, S.D.4    Coffman, R.L.5    Flavell, R.A.6
  • 26
    • 17144400393 scopus 로고    scopus 로고
    • TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells
    • Marie JC, Letterio JJ, Gavin M, Rudensky AY. TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells. J Exp Med 2005 201 : 1061 7.
    • (2005) J Exp Med , vol.201 , pp. 1061-7
    • Marie, J.C.1    Letterio, J.J.2    Gavin, M.3    Rudensky, A.Y.4
  • 27
    • 1642577126 scopus 로고    scopus 로고
    • TGF-beta1 plays an important role in the mechanism of CD4+ CD25+ regulatory T cell activity in both humans and mice
    • Nakamura K, Kitani A, Fuss I, Pedersen A, Harada N, Nawata H, et al. TGF-beta1 plays an important role in the mechanism of CD4+ CD25+ regulatory T cell activity in both humans and mice. J Immunol 2004 172 : 834 42.
    • (2004) J Immunol , vol.172 , pp. 834-42
    • Nakamura, K.1    Kitani, A.2    Fuss, I.3    Pedersen, A.4    Harada, N.5    Nawata, H.6
  • 28
    • 35548992776 scopus 로고    scopus 로고
    • Insulin VNTR I/III genotype is associated with autoantibodies against glutamic acid decarboxylase in newly diagnosed type 1 diabetes
    • Rajasalu T, Haller K, Salur L, Kisand K, Tillmann V, Schlosser M, et al. Insulin VNTR I/III genotype is associated with autoantibodies against glutamic acid decarboxylase in newly diagnosed type 1 diabetes. Diabetes Metab Res Rev 2007 23 : 567 71.
    • (2007) Diabetes Metab Res Rev , vol.23 , pp. 567-71
    • Rajasalu, T.1    Haller, K.2    Salur, L.3    Kisand, K.4    Tillmann, V.5    Schlosser, M.6
  • 30
  • 31
    • 33747801470 scopus 로고    scopus 로고
    • IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo
    • Zorn E, Nelson EA, Mohseni M, Porcheray F, Kim H, Litsa D, et al. IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo. Blood 2006 108 : 1571 9.
    • (2006) Blood , vol.108 , pp. 1571-9
    • Zorn, E.1    Nelson, E.A.2    Mohseni, M.3    Porcheray, F.4    Kim, H.5    Litsa, D.6
  • 32
    • 36048978911 scopus 로고    scopus 로고
    • Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature
    • Hill JA, Feuerer M, Tash K, Haxhinasto S, Perez J, Melamed R, et al. Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature. Immunity 2007 27 : 786 800.
    • (2007) Immunity , vol.27 , pp. 786-800
    • Hill, J.A.1    Feuerer, M.2    Tash, K.3    Haxhinasto, S.4    Perez, J.5    Melamed, R.6
  • 33
    • 33847125247 scopus 로고    scopus 로고
    • Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
    • Wan YY, Flavell RA. Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature 2007 445 : 766 70.
    • (2007) Nature , vol.445 , pp. 766-70
    • Wan, Y.Y.1    Flavell, R.A.2
  • 34
    • 37149003363 scopus 로고    scopus 로고
    • Compromised CD4+CD25high regulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level
    • Venken K, Hellings N, Thewissen M, Somers V, Hensen K, Rummens JL, et al. Compromised CD4+CD25high regulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level. Immunology 2008 123 : 79 89.
    • (2008) Immunology , vol.123 , pp. 79-89
    • Venken, K.1    Hellings, N.2    Thewissen, M.3    Somers, V.4    Hensen, K.5    Rummens, J.L.6
  • 35
    • 34848858303 scopus 로고    scopus 로고
    • Enhanced efficacy of regulatory T cell transfer against increasing resistance, by elevated Foxp3 expression induced in arthritic murine hosts
    • Ohata J, Miura T, Johnson TA, Hori S, Ziegler SF, Kohsaka H. Enhanced efficacy of regulatory T cell transfer against increasing resistance, by elevated Foxp3 expression induced in arthritic murine hosts. Arthritis Rheum 2007 56 : 2947 56.
    • (2007) Arthritis Rheum , vol.56 , pp. 2947-56
    • Ohata, J.1    Miura, T.2    Johnson, T.A.3    Hori, S.4    Ziegler, S.F.5    Kohsaka, H.6
  • 36
    • 0347990607 scopus 로고    scopus 로고
    • Transmission of maternal islet antibodies and risk of autoimmune diabetes in offspring of mothers with type 1 diabetes
    • Koczwara K, Bonifacio E, Ziegler AG. Transmission of maternal islet antibodies and risk of autoimmune diabetes in offspring of mothers with type 1 diabetes. Diabetes 2004 53 : 1 4.
    • (2004) Diabetes , vol.53 , pp. 1-4
    • Koczwara, K.1    Bonifacio, E.2    Ziegler, A.G.3
  • 37
    • 33750874347 scopus 로고    scopus 로고
    • Evidence for immunological priming and increased frequency of CD4+CD25+ cord blood T cells in children born to mothers with type 1 diabetes
    • Holm BC, Svensson J, Åkesson C, Arvastsson J, Ljungberg J, Lynch K, et al. Evidence for immunological priming and increased frequency of CD4+CD25+ cord blood T cells in children born to mothers with type 1 diabetes. Clin Exp Immunol 2006 146 : 493 502.
    • (2006) Clin Exp Immunol , vol.146 , pp. 493-502
    • Holm, B.C.1    Svensson, J.2    Åkesson, C.3    Arvastsson, J.4    Ljungberg, J.5    Lynch, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.