PKR regulates B56α-mediated BCL2 phosphatase activity in acute lymphoblastic leukemia-derived REH cells

Journal of Biological Chemistry

Volumn 283, Issue 51, 2008, Pages 35474-35485

  Ruvolo, Vivian R ^a   Kurinna, Svitlana M ^b   Karanjeet, Kul B ^a   Schuster, Todd F ^a   Martelli, Alberto M ^c   McCubrey, James A ^d   Ruvolo, Peter P ^a,b  

^a University of Minnesota Hormel Institute   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d EAST CAROLINA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CHEMICAL REACTIONS; LAWS AND LEGISLATION; PHOSPHORYLATION; POLARIZATION;

ACUTE LYMPHOBLASTIC LEUKEMIAS; DEPHOSPHORYLATION; ETOPOSIDE; FAMILY MEMBERS; HETEROTRIMER; IN VITRO; PHOSPHATASE ACTIVITIES; PROTEASOME INHIBITORS; PROTEIN PHOSPHATASES; WILD TYPES;

RHENIUM COMPOUNDS;

BCL2 PHOSPHATASE; ETOPOSIDE; INITIATION FACTOR 2ALPHA; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; PHOSPHATASE; PHOSPHOPROTEIN; PHOSPHOPROTEIN PHOSPHATASE 2A; PHOSPHOTRANSFERASE; PROTEASOME; PROTEASOME INHIBITOR; PROTEIN B56ALPHA; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN PKR; PROTEIN SUBUNIT; SERINE; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CELL STRESS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; GENE MUTATION; HUMAN; HUMAN CELL; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION;

AMINO ACID SUBSTITUTION; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; EIF-2 KINASE; ETOPOSIDE; EUKARYOTIC INITIATION FACTOR-2B; HUMANS; MUTATION, MISSENSE; PHOSPHORYLATION; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTEIN PHOSPHATASE 2; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION;

EID: 58149083332     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M800951200     Document Type: Article

References (43)

1. Fujiki, H., and Suganuma, M. (1993) Adv. Cancer Res. 61, 143-194
2. Van Hoof, C., and Goris, J. (2003) Biochim. Biophys. Acta 1640, 97-104
3. Janssens, V., Goris, J., and Van Hoof, C. (2005) Curr. Opin. Genet. Dev. 15, 34-41
4. Mumby, M. (2007) ACS Chem. Biol. 2, 99-103
5. Mumby, M. (1995) Semin. Cancer Biol. 6, 229-237
6. Silverstein, A. M., Barrow, C. A., Davis, A. J., and Mumby, M. C. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 4221-4226
7. Strack, S., Cribbs, J. T., and Gomez, L. (2004) J. Biol. Chem. 279, 47732-47739
8. Mumby, M. C., and Walter, G. (1993) Physiol. Rev. 73, 673-699
9. McCright, B., and Virshup, D. M. (1995) J. Biol. Chem. 270, 26123-26128
10. Ruediger, R., Van Wart Hood, J. E., Mumby, M., and Walter, G. (1991) Mol. Cell. Biol. 12, 4282-4285
11. Seeling, J. M., Miller, J. R., Gil, R., Moon, R. T., White, R., and Virshup, D. M. (1999) Science 283, 2089-2091
12. Ruvolo, P. P., Clark, W., Mumby, M., Gao, F., and May, W. S. (2002) J. Biol. Chem. 277, 22847-22852
13. Cho, U. S., and Xu, W. (2007) Nature 445, 53-57
14. Chen, Y., Xu, Y., Bao, Q., Xing, Y., Li, Z., Lin, Z., Stock, J. B., Jeffrey, P. D., and Shi, Y. (2007) Nat. Struct. Mol. Biol. 14, 527-534
15. Xu, Y., Xing, Y., Chen, Y., Chao, Y., Lin, Z., Fan, E., Yu, J. W., Strack, S., Jeffrey, P. D., and Shi, Y. (2006) Cell 127, 1239-1251
16. Chen, J., Martin, B. L., and Brautigan, D. L. (1992) Science 257, 1261-1264
17. McCright, B., Rivers, A. M., Audlin, S., and Virshup, D. M. (1996) J. Biol. Chem. 271, 22081-22089
18. Letourneux, C., Rocher, G., and Porteu, F. (2006) EMBO J. 25, 727-738
19. Xu, Z., and Williams, B. R. (2000) Mol. Cell. Biol. 20, 5285-5299
20. Williams, B. R. (1999) Oncogene 18, 6112-6120
21. Williams, B. R. (2001) Sci. STKE 2001, RE2
22. Garcia, M. A., Gil, J., Ventoso, I., Guerra, S., Domingo, E., Rivas, C., and Esteban, M. (2006) Microbiol. Mol. Biol. Rev. 70, 1032-1060
23. García, M. A., Meurs, E. F., and Esteban, M. (2007) Biochimie (Paris) 89, 799-811
24. Ruvolo, P. P., Deng, X., Carr, B. K., and May, W. S. (1998) J. Biol. Chem. 273, 25436-25442
25. Raven, J. F., Baltzis, D., Wang, S., Mounir, Z., Papadakis, A. I., Gao, H. Q., and Koromilas, A. E. (2008) J. Biol. Chem. 283, 3097-3108
26. Kazemi, S., Mounir, Z., Baltzis, D., Raven, J. F., Wang, S., Krishnamoorthy, J. L., Pluquet, O., Pelletier, J., and Koromilas, A. E. (2007) Mol. Biol. Cell 18, 3635-3644
27. O'Doherty, U., Swiggard, W. J., and Malim, M. H. (2000) J. Virol. 74, 10074-10080
28. Cole, J. L. (2007) Trends Biochem. Sci. 32, 57-62
29. Boyce, M., Bryant, K. F., Jousse, C., Long, K., Harding, H. P., Scheuner, D., Kaufman, R. J., Ma, D., Coen, D. M., Ron, D., and Yuan, J. (2005) Science 307, 935-939
30. Sears, R., Nuckolls, F., Haura, E., Taya, Y., Tamai, K., and Nevins, J. R. (2000) Genes Dev. 14, 2501-2514
31. Maurer, U., Charvet, C., Wagman, A. S., Dejardin, E., and Green, D. R. (2006) Mol. Cell 21, 749-760
32. Cross, D. A., Alessi, D. R., Cohen, P., Andjelkovich, M., and Hemmings, B. A. (1995) Nature 378, 785-789
33. Steelman, L. S., Stadelman, K. M., Chappell, W. H., Horn, S., Bäsecke, J., Cervello, M., Nicoletti, F., Libra, M., Stivala, F., Martelli, A. M., and McCubrey, J. A. (2008) Expert Opin. Ther. Targets 12, 1139-1165
34. Wullschleger, S., Loewith, R., and Hall, M. N. (2006) Cell 124, 471-484
35. Guo, C. Y., Brautigan, D. L., and Larner, J. M. (2002) J. Biol. Chem. 277, 4839-4844
36. Abraham, N., Jaramillo, M. L., Duncan, P. I., Methot, N., Icely, P. L., Stojdl, D. F., Barber, G. N., and Bell, J. C. (1998) Exp. Cell Res. 244, 394-404
37. Beretta, L., Gabbay, M., Berger, R., Hanash, S. M., and Sonenberg, N. (1996) Oncogene 12, 1593-1596
38. Hii, S. I., Hardy, L., Crough, T., Payne, E. J., Grimmett, K., Gill, D., and McMillan, N. A. (2004) Int. J. Cancer 109, 329-335
39. Murad, J. M., Tone, L. G., de Souza, L. R., and De Lucca, F. L. (2005) Blood Cells Mol. Dis. 34, 1-5
40. Basu, S., Panayiotidis, P., Hart, S. M., He, L. Z., Man, A., Hoffbrand, A. V., and Ganeshaguru, K. (1997) Cancer Res. 57, 943-947
41. Neviani, P., Santhanam, R., Trotta, R., Notari, M., Blaser, B. W., Liu, S., Mao, H., Chang, J. S., Galietta, A., Uttam, A., Roy, D. C., Valtieri, M., Bruner-Klisovic, R., Caligiuri, M. A., Bloomfield, C. D., Marcucci, G., and Perrotti, D. (2005) Cancer Cell 8, 355-368
42. Perrotti, D., and Neviani, P. (2006) Br. J. Cancer 95, 775-781
43. Liu, Q., Zhao, X., Frissora, F., Ma, Y., Santhanam, R., Jarjoura, D., Lehman, A., Perrotti, D., Chen, C. S., Dalton, J. T., Muthusamy, N., and Byrd, J. C. (2008) Blood 111, 275-284