Protein polarization is critical to stabilizing AF-2 and helix-2′ domains in ligand binding to PPAR-γ

Journal of the American Chemical Society

Volumn 130, Issue 50, 2008, Pages 17129-17133

  Ji, C G ^a   Zhang, J Z H ^b,c  

^a NANJING UNIVERSITY   (China)

^b EAST CHINA NORMAL UNIVERSITY   (China)

^c NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION FUNCTIONS; ADIPOCYTE DIFFERENTIATIONS; DO-MAINS; ELECTRONIC POLARIZATIONS; EXPERIMENTAL OBSERVATIONS; FORCE FIELDS; GLUCOSE HOMEOSTASISES; HELIX STRUCTURES; HYDROGEN BONDINGS; LIGAND BINDINGS; LOCAL STRUCTURES; MD SIMULATIONS; NATIVE STRUCTURES; NUMERICAL RESULTS; PEROXISOME PROLIFERATOR- ACTIVATED RECEPTORS; RANDOM STRUCTURES; ROSIGLITAZONE;

BIOCHEMISTRY; CYTOLOGY; GLUCOSE; HYDROGEN; HYDROGEN BONDS; LIGANDS; POLARIZATION; TRANSCRIPTION FACTORS;

BIOACTIVITY;

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ARTICLE; HYDROGEN BOND; MOLECULAR DYNAMICS; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; LIGANDS; MODELS, MOLECULAR; PPAR GAMMA; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; TIME FACTORS;

EID: 58049209744     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja807374x     Document Type: Article

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