Optimization of antimicrobial drug gramicidin S dosing regime using biosimulations

European Journal of Pharmaceutical Sciences

Volumn 36, Issue 1, 2009, Pages 105-109

  Smirnov, S ^a   Belashov, A ^b   Demin, O ^a,c  

^a Institute for Systems Biology SPb   (Russian Federation)

^b JSC Valenta Pharm   (Russian Federation)

^c MOSCOW STATE UNIVERSITY   (Russian Federation)

Author keywords

Bacteria; Gramicidin S; Mechanism based mathematical model; Oral melting tablet

Indexed keywords

GRAMICIDIN S;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BACTERICIDAL ACTIVITY; DRUG ABSORPTION; DRUG EFFICACY; DRUG SALIVA LEVEL; DRUG TRANSFORMATION; ENTEROBACTER; HUMAN; MATHEMATICAL MODEL; MINIMUM INHIBITORY CONCENTRATION; MOUTH FLORA; MYCOBACTERIUM LEPRAE; OPTIMAL DRUG DOSE; ORAL MELTING TABLET; PHARMACODYNAMICS; PRIORITY JOURNAL; SALIVATION; SIMULATION; STAPHYLOCOCCUS AUREUS; TABLET;

ALGORITHMS; ANTI-INFECTIVE AGENTS, LOCAL; BACTERIA; COMPUTER SIMULATION; GRAMICIDIN; HUMANS; MICROBIAL SENSITIVITY TESTS; MODELS, STATISTICAL; MOUTH; TABLETS;

EID: 58049195553     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2008.10.017     Document Type: Article

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