Influence of DNA repair gene polymorphisms on the initial repair of MMS-induced DNA damage in human lymphocytes as measured by the alkaline comet assay

Environmental and Molecular Mutagenesis

Volumn 49, Issue 9, 2008, Pages 669-675

  Ryk, Charlotta ^a   Routledge, Michael N ^b   Allan, James M ^c   Wild, Christopher P ^b   Kumar, Rajiv ^a,d   Lambert, Bo ^a   Hou, Saimei ^a,e  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF LEEDS   (United Kingdom)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^e ASTRAZENECA R AND D   (Sweden)

Author keywords

Alkaline comet assay; Base excision repair; Gene polymorphisms; Homologous recombination; Methylmethane sulphonate

Indexed keywords

MESYLIC ACID METHYL ESTER; NIBRIN; NUCLEAR PROTEIN; PHYTOHEMAGGLUTININ; PROTEIN APEX1; PROTEIN MLH1; UNCLASSIFIED DRUG; XERODERMA PIGMENTOSUM GROUP D PROTEIN; XRCC1 PROTEIN; XRCC3 PROTEIN;

ARTICLE; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DNA POLYMORPHISM; DNA REPAIR; EXCISION REPAIR; GENOTYPE; HUMAN; HUMAN CELL; MISMATCH REPAIR; OUTCOME ASSESSMENT; PERIPHERAL LYMPHOCYTE;

EID: 58049192776     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20415     Document Type: Article

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