Single nucleotide polymorphisms in DNA repair genes and basal cell carcinoma of skin

Carcinogenesis

Volumn 27, Issue 8, 2006, Pages 1676-1681

  Thirumaran, Ranjit Kumar ^a   Bermejo, Justo Lorenzo ^a   Rudnai, Peter ^b   Gurzau, Eugene ^c   Koppova, Kvetoslava ^d   Goessler, Walter ^e   Vahter, Marie ^f   Leonardi, Giovanni S ^g   Clemens, Felicity ^g   Fletcher, Tony ^g   Hemminki, Kari ^a,f   Kumar, Rajiv ^a,f  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH   (Hungary)

^c Environmental Health Center   (Romania)

^d State Health Institute Banska   (Slovakia)

^e UNIVERSITY OF GRAZ   (Austria)

^f KAROLINSKA INSTITUTE   (Sweden)

^g LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN XRCC3; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BASAL CELL CARCINOMA; CANCER RISK; CONFIDENCE INTERVAL; CONTROLLED STUDY; DNA REPAIR; DNA SEQUENCE; ENVIRONMENTAL FACTOR; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUNGARY; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; ROMANIA; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SLOVAKIA; SUN EXPOSURE;

EID: 33747875848     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgi381     Document Type: Article

References (38)

1. Bowden,G.T. (2004) Prevention of non-melanoma skin cancer by targeting ultraviolet-B-light signalling. Nat. Rev. Cancer, 4, 23-35.
2. Tsai,K.Y. and Tsao,H. (2004) The genetics of skin cancer. Am. J. Med. Genet. C. Semin. Med. Genet., 131C, 82-92.
3. Tsao,H. (2001) Genetics of nonmelanoma skin cancer. Arch. Dermatol., 137, 1486-1492.
4. Green,C.L. and Khavari,P.A. (2004) Targets for molecular therapy of skin cancer. Semin. Cancer Biol., 14, 63-69.
5. Lovatt,T.J., Lear,J.T., Bastrilles,J. et al. (2005) Associations between ultraviolet radiation, basal cell carcinoma site and histology, host characteristics, and rate of development of further tumors. J. Am. Acad. Dermatol., 52, 468-473.
6. de Gruijl,F.R., van Kranen,H.J. and Mullenders,L.H. (2001) UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer. J. Photochem. Photobiol. B, 63, 19-27.
7. Karagas,M.R., Stukel,T.A., Morris,J.S., Tosteson,T.D., Weiss,J.E., Spencer,S.K. and Greenberg,E.R. (2001) Skin cancer risk in relation to toenail arsenic concentrations in a US population-based case-control study. Am. J. Epidemiol., 153, 559-565.
8. Berwick,M. and Vineis,P. (2005) Measuring DNA repair capacity: Small steps. J. Natl Cancer Inst., 97, 84-85.
9. Berwick,M. and Vineis,P. (2000) Markers of DNA repair and susceptibility to cancer in humans: An epidemiologic review. J. Natl. Cancer Inst., 92, 874-897.
10. Xu,G., Snellman,E., Bykov,V.J., Jansen,C.T. and Hemminki,K. (2000) Effect of age on the formation and repair of UV photoproducts in human skin in situ. Mutat. Res., 459, 195-202.
11. Bykov,V.J., Sheehan,J.M., Hemminki,K. and Young,A.R. (1999) In situ repair of cyclobutane pyrimidine dimers and 6-4 photoproducts in human skin exposed to solar simulating radiation. J. Invest. Dermatol., 112, 326-331.
12. Wei,Q., Matanoski,G.M., Farmer,E.R., Hedayati,M.A. and Grossman,L. (1995) DNA repair capacity for ultraviolet light-induced damage is reduced in peripheral lymphocytes from patients with basal cell carcinoma. J. Invest. Dermatol., 104, 933-936.
13. Wei,Q., Matanoski,G.M., Farmer,E.R., Hedayati,M.A. and Grossman,L. (1993) DNA repair and aging in basal cell carcinoma: A molecular epidemiology study. Proc. Natl Acad. Sci. USA, 90, 1614-1618.
14. Mohrenweiser,H.W., Xi,T., Vazquez-Matias,J. and Jones,I.M. (2002) Identification of 127 amino acid substitution variants in screening 37 DNA repair genes in humans. Cancer Epidemiol. Biomarkers Prev., 11, 1054-1064.
15. Kuschel,B., Auranen,A., McBride,S. et al. (2002) Variants in DNA double-strand break repair genes and breast cancer susceptibility. Hum. Mol. Genet., 11, 1399-1407.
16. Hung,R.J., Brennan,P., Canzian,F. et al. (2005) Large-scale investigation of base excision repair genetic polymorphisms and lung cancer risk in a multicenter study. J. Natl Cancer Inst., 97, 567-576.
17. Han,J., Hankinson,S.E., Colditz,G.A. and Hunter,D.J. (2004) Genetic variation in XRCC1, sun exposure, and risk of skin cancer. Br. J. Cancer, 91, 1604-1609.
18. Lovatt,T., Alldersea,J., Lear,J.T., Hoban,P.R., Ramachandran,S., Fryer,A.A., Smith,A.G. and Strange,R.C. (2005) Polymorphism in the nuclear excision repair gene ERCC2/XPD: Association between an exon 6-exon 10 haplotype and susceptibility to cutaneous basal cell carcinoma. Hum. Mutat., 25, 353-359.
19. Han,J., Colditz,G.A., Samson,L.D. and Hunter,D.J. (2004) Polymorphisms in DNA double-strand break repair genes and skin cancer risk. Cancer Res., 64, 3009-3013.
20. Han,J., Colditz,G.A., Liu,J.S. and Hunter,D.J. (2005) Genetic variation in XPD, sun exposure, and risk of skin cancer. Cancer Epidemiol. Biomarkers Prev., 14, 1539-1544.
21. Festa,F., Kumar,R., Sanyal,S., Unden,B., Nordfors,L., Lindholm,B., Snellman,E., Schalling,M., Forsti,A. and Hemminki,K. (2005) Basal cell carcinoma and variants in genes coding for immune response, DNA repair, folate and iron metabolism. Mutat Res., 574, 105-111.
22. Jacobsen,N.R., Nexo,B.A., Olsen,A., Overvad,K., Wallin,H., Tjonneland,A. and Vogel,U. (2003) No association between the DNA repair gene XRCC3 T241M polymorphism and risk of skin cancer and breast cancer. Cancer Epidemiol. Biomarkers Prev., 12, 584-585.
23. Lindberg,A.L., Goessler,W., Gurzau,E. et al. (2006) Arsenic exposure in Hungary, Romania and Slovakia. J. Environ. Monit., 8, 203-208.
24. Westfall,P.H. and Young,S.S. (1993) Resampling-Based Multiple Testing. John Wiley & Sons, New York.
25. Sanyal,S., Festa,F., Sakano,S., Zhang,Z., Steineck,G., Norming,U., Wijkstrom,H., Larsson,P., Kumar,R. and Hemminki,K. (2004) Polymorphisms in DNA repair and metabolic genes in bladder cancer. Carcinogenesis, 25, 729-734.
26. Vodicka,P., Kumar,R., Stetina,R. et al. (2004) Genetic polymorphisms in DNA repair genes and possible links with DNA repair rates, chromosomal aberrations and single-strand breaks in DNA. Carcinogenesis, 25, 757-763.
27. Hunter,D.J. (2005) Gene-environment interactions in human diseases. Nat. Rev. Genet., 6, 287-298.
28. Nelson,H.H., Kelsey,K.T., Mott,L.A. and Karagas,M.R. (2002) The XRCC1 Arg399Gln polymorphism, sunburn, and non-melanoma skin cancer: Evidence of gene environment interaction. Cancer Res., 62, 152-155.
29. Pharoah,P.D., Dunning,A.M., Ponder,B.A. and Easton,D.F. (2004) Association studies for finding cancer-susceptibility genetic variants. Nat. Rev. Cancer, 4, 850-860.
30. Wacholder,S., Chanock,S., Garcia-Closas,M., El Ghormli,L. and Rothman,N. (2004) Assessing the probability that a positive report is false: An approach for molecular epidemiology studies. J. Natl Cancer Inst., 96, 434-442.
31. Thacker,J. (2005) The RAD51 gene family, genetic instability and cancer. Cancer Lett., 219, 125-135.
32. Arthur,L.M., Gustausson,K., Hopfner,K.P., Carson,C.T., Stracker,T.H., Karcher,A., Felton,D., Weitzman,M.D., Tainer,J. and Carney,J.P. (2004) Structural and functional analysis of Mre11-3. Nucleic Acids Res., 32, 1886-1893.
33. Savas,S., Kim,D.Y., Ahmad,M.F., Shariff,M. and Ozcelik,H. (2004) Identifying functional genetic variants in DNA repair pathway using protein conservation analysis. Cancer Epidemiol. Biomarkers Prev., 13, 801-807.
34. Matullo,G., Palli,D., Peluso,M. et al. (2001) XRCC1, XRCC3, XPD gene polymorphisms, smoking and (32)P-DNA adducts in a sample of healthy subjects. Carcinogenesis, 22, 1437-1445.
35. Araujo,F.D., Pierce,A.J., Stark,J.M. and Jasin,M. (2002) Variant XRCC3 implicated in cancer is functional in homology-directed repair of double-strand breaks. Oncogene, 21, 4176-4180.
36. Kobayashi,J., Antoccia,A., Tauchi,H., Matsuura,S. and Komatsu,K. (2004) NBS1 and its functional role in the DNA damage response. DNA Repair (Amst.), 3, 855-861.
37. Medina,P.P., Ahrendt,S.A., Pollan,M., Fernandez,P., Sidransky,D. and Sanchez-Cespedes,M. (2003) Screening of homologous recombination gene polymorphisms in lung cancer patients reveals an association of the NBS1-185Gln variant and p53 gene mutations. Cancer Epidemiol. Biomarkers Prev., 12, 699-704.
38. Hussain,S., Witt,E., Huber,P.A.J., Medhurst,A.L., Ashworth,A. and Mathew,C.G. (2003) Direct interaction of the Fanconi anaemia protein FANCG with BRCA2/FANCD1. Hum. Mol. Genet., 12, 2503-2510.