Role of mitochondrial oxidative stress in the apoptosis induced by diospyrin diethylether in human breast carcinoma (MCF-7) cells

Molecular and Cellular Biochemistry

Volumn 320, Issue 1-2, 2009, Pages 185-195

  Kumar, Binod ^a   Kumar, Amit ^b   Pandey, B N ^b   Mishra, K P ^c,d   Hazra, Banasri ^a  

^a JADAVPUR UNIVERSITY   (India)

^b BHABHA ATOMIC RESEARCH CENTRE   (India)

^c NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY   (India)

^d UNIVERSITY OF MUMBAI   (India)

Author keywords

Apoptosis; Cytochrome c; Human breast carcinoma; Mitochondrial membrane potential; Mitochondrial permeability transition; Oxidative stress; Quinonoids; ROS

Indexed keywords

ANTIOXIDANT; CARDIOLIPIN; CYCLOSPORIN A; CYTOCHROME C; DIOSPYRIN; DIOSPYRIN DIETHYL ETHER; NAC; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CARCINOMA; CELL PROLIFERATION; CELL STRAIN MCF 7; CELL ULTRASTRUCTURE; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; ELECTRON TRANSPORT; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MITOCHONDRIAL PERMEABILITY; MITOCHONDRIAL RESPIRATION; MOLECULAR DYNAMICS; OXIDATION; OXIDATIVE STRESS; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION;

ACETYLCYSTEINE; ALLOPURINOL; ANIMALS; ANTIMYCIN A; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; CARDIOLIPINS; CELL LINE, TUMOR; CYCLOSPORINE; CYTOCHROMES C; FEMALE; FREE RADICAL SCAVENGERS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NAPHTHOQUINONES; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; ROTENONE; UNCOUPLING AGENTS; VITAMIN K 3;

EID: 58049172579     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-008-9920-4     Document Type: Article

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