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Volumn 14, Issue 28, 2008, Pages 4434-4439

Molecular basis of the potential of mesalazine to prevent colorectal cancer

Author keywords

Chemoprevention; Colorectal cancer; Cyclooxygenase 2; Epidermal growth factor receptor; Inflammatory bowel disease; Mesalazine; Wnt catenin

Indexed keywords

BETA CATENIN; CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; MESALAZINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; WNT PROTEIN;

EID: 58049107852     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.14.4434     Document Type: Editorial
Times cited : (34)

References (60)
  • 1
    • 0035080617 scopus 로고    scopus 로고
    • The risk of colorectal cancer in ulcerative colitis: A meta-analysis
    • Eaden JA, Abrams KR, Mayberry JF. The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut 2001; 48: 526-535
    • (2001) Gut , vol.48 , pp. 526-535
    • Eaden, J.A.1    Abrams, K.R.2    Mayberry, J.F.3
  • 2
    • 33644820014 scopus 로고    scopus 로고
    • Increased risk of intestinal cancer in Crohn's disease: A meta-analysis of population-based cohort studies
    • Jess T, Gamborg M, Matzen P, Munkholm P, Sorensen TI. Increased risk of intestinal cancer in Crohn's disease: a meta-analysis of population-based cohort studies. Am J Gastroenterol 2005; 100: 2724-2729
    • (2005) Am J Gastroenterol , vol.100 , pp. 2724-2729
    • Jess, T.1    Gamborg, M.2    Matzen, P.3    Munkholm, P.4    Sorensen, T.I.5
  • 3
    • 0141651527 scopus 로고    scopus 로고
    • Review article: The incidence and prevalence of colorectal cancer in inflammatory bowel disease
    • Munkholm P. Review article: the incidence and prevalence of colorectal cancer in inflammatory bowel disease. Aliment Pharmacol Ther 2003; 18 Suppl 2: 1-5
    • (2003) Aliment Pharmacol Ther , vol.18 , Issue.SUPPL. 2 , pp. 1-5
    • Munkholm, P.1
  • 5
    • 34848893583 scopus 로고    scopus 로고
    • Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: A cohort study
    • quiz 1340-1341
    • Gupta RB, Harpaz N, Itzkowitz S, Hossain S, Matula S, Kornbluth A, Bodian C, Ullman T. Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study. Gastroenterology 2007; 133: 1099-1105; quiz 1340-1341
    • (2007) Gastroenterology , vol.133 , pp. 1099-1105
    • Gupta, R.B.1    Harpaz, N.2    Itzkowitz, S.3    Hossain, S.4    Matula, S.5    Kornbluth, A.6    Bodian, C.7    Ullman, T.8
  • 6
    • 4844228230 scopus 로고    scopus 로고
    • Review article: Colorectal carcinoma and inflammatory bowel disease
    • Eaden J. Review article: colorectal carcinoma and inflammatory bowel disease. Aliment Pharmacol Ther 2004; 20 Suppl 4: 24-30
    • (2004) Aliment Pharmacol Ther , vol.20 , Issue.SUPPL. 4 , pp. 24-30
    • Eaden, J.1
  • 7
    • 33748305574 scopus 로고    scopus 로고
    • Review article: Colorectal cancer surveillance in ulcerative colitis - what should we be doing?
    • Obrador A, Ginard D, Barranco L. Review article: colorectal cancer surveillance in ulcerative colitis - what should we be doing? Aliment Pharmacol Ther 2006; 24 Suppl 3: 56-63
    • (2006) Aliment Pharmacol Ther , vol.24 , Issue.SUPPL. 3 , pp. 56-63
    • Obrador, A.1    Ginard, D.2    Barranco, L.3
  • 9
    • 21344446543 scopus 로고    scopus 로고
    • Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: A systematic review and metaanalysis of observational studies
    • Velayos FS, Terdiman JP, Walsh JM. Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: a systematic review and metaanalysis of observational studies. Am J Gastroenterol 2005; 100: 1345-1353
    • (2005) Am J Gastroenterol , vol.100 , pp. 1345-1353
    • Velayos, F.S.1    Terdiman, J.P.2    Walsh, J.M.3
  • 10
    • 25144459131 scopus 로고    scopus 로고
    • 5-Aminosalicylate use and colorectal cancer risk in inflammatory bowel disease: A large epidemiological study
    • Van Staa TP, Card T, Logan RF, Leufkens HG. 5-Aminosalicylate use and colorectal cancer risk in inflammatory bowel disease: a large epidemiological study. Gut 2005; 54: 1573-1578
    • (2005) Gut , vol.54 , pp. 1573-1578
    • Van Staa, T.P.1    Card, T.2    Logan, R.F.3    Leufkens, H.G.4
  • 12
    • 0347994976 scopus 로고    scopus 로고
    • Does the use of 5-aminosalicylates in inflammatory bowel disease prevent the development of colorectal cancer?
    • Bernstein CN, Blanchard JF, Metge C, Yogendran M. Does the use of 5-aminosalicylates in inflammatory bowel disease prevent the development of colorectal cancer? Am J Gastroenterol 2003; 98: 2784-2788
    • (2003) Am J Gastroenterol , vol.98 , pp. 2784-2788
    • Bernstein, C.N.1    Blanchard, J.F.2    Metge, C.3    Yogendran, M.4
  • 13
    • 0033637218 scopus 로고    scopus 로고
    • Mesalazine inhibits activation of transcription factor NF-kappaB in inflamed mucosa of patients with ulcerative colitis
    • Bantel H, Berg C, Vieth M, Stolte M, Kruis W, Schulze-Osthoff K. Mesalazine inhibits activation of transcription factor NF-kappaB in inflamed mucosa of patients with ulcerative colitis. Am J Gastroenterol 2000; 95: 3452-3457
    • (2000) Am J Gastroenterol , vol.95 , pp. 3452-3457
    • Bantel, H.1    Berg, C.2    Vieth, M.3    Stolte, M.4    Kruis, W.5    Schulze-Osthoff, K.6
  • 14
    • 0033047588 scopus 로고    scopus 로고
    • Mesalamine blocks tumor necrosis factor growth inhibition and nuclear factor kappaB activation in mouse colonocytes
    • Kaiser GC, Yan F, Polk DB. Mesalamine blocks tumor necrosis factor growth inhibition and nuclear factor kappaB activation in mouse colonocytes. Gastroenterology 1999; 116: 602-609
    • (1999) Gastroenterology , vol.116 , pp. 602-609
    • Kaiser, G.C.1    Yan, F.2    Polk, D.B.3
  • 15
    • 0026081338 scopus 로고
    • 5-Aminosalicylic acid is a potent inhibitor of interleukin 1 beta production in organ culture of colonic biopsy specimens from patients with inflammatory bowel disease
    • Mahida YR, Lamming CE, Gallagher A, Hawthorne AB, Hawkey CJ. 5-Aminosalicylic acid is a potent inhibitor of interleukin 1 beta production in organ culture of colonic biopsy specimens from patients with inflammatory bowel disease. Gut 1991; 32: 50-54
    • (1991) Gut , vol.32 , pp. 50-54
    • Mahida, Y.R.1    Lamming, C.E.2    Gallagher, A.3    Hawthorne, A.B.4    Hawkey, C.J.5
  • 16
    • 0033210896 scopus 로고    scopus 로고
    • 5-aminosalicylic acid inhibits iNOS transcription in human intestinal epithelial cells
    • Kennedy M, Wilson L, Szabo C, Salzman AL. 5-aminosalicylic acid inhibits iNOS transcription in human intestinal epithelial cells. Int J Mol Med 1999; 4: 437-443
    • (1999) Int J Mol Med , vol.4 , pp. 437-443
    • Kennedy, M.1    Wilson, L.2    Szabo, C.3    Salzman, A.L.4
  • 17
    • 0023156602 scopus 로고
    • Effect of sulphasalazine and its metabolites on the generation of reactive oxygen species
    • Miyachi Y, Yoshioka A, Imamura S, Niwa Y. Effect of sulphasalazine and its metabolites on the generation of reactive oxygen species. Gut 1987; 28: 190-195
    • (1987) Gut , vol.28 , pp. 190-195
    • Miyachi, Y.1    Yoshioka, A.2    Imamura, S.3    Niwa, Y.4
  • 22
    • 0034220766 scopus 로고    scopus 로고
    • Chemoprevention of colon cancer carcinogenesis by balsalazide: Inhibition of azoxymethane-induced aberrant crypt formation in the rat colon and intestinal tumor formation in the B6-Min/+ mouse
    • MacGregor DJ, Kim YS, Sleisenger MH, Johnson LK. Chemoprevention of colon cancer carcinogenesis by balsalazide: inhibition of azoxymethane-induced aberrant crypt formation in the rat colon and intestinal tumor formation in the B6-Min/+ mouse. Int J Oncol 2000; 17: 173-179
    • (2000) Int J Oncol , vol.17 , pp. 173-179
    • MacGregor, D.J.1    Kim, Y.S.2    Sleisenger, M.H.3    Johnson, L.K.4
  • 25
    • 0032542364 scopus 로고    scopus 로고
    • Genetic instabilities in human cancers
    • Lengauer C, Kinzler KW, Vogelstein B. Genetic instabilities in human cancers. Nature 1998; 396: 643-649
    • (1998) Nature , vol.396 , pp. 643-649
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 26
    • 0027285475 scopus 로고
    • Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
    • Ionov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993; 363: 558-561
    • (1993) Nature , vol.363 , pp. 558-561
    • Ionov, Y.1    Peinado, M.A.2    Malkhosyan, S.3    Shibata, D.4    Perucho, M.5
  • 27
    • 20144375231 scopus 로고    scopus 로고
    • Mesalazine improves replication fidelity in cultured colorectal cells
    • Gasche C, Goel A, Natarajan L, Boland CR. Mesalazine improves replication fidelity in cultured colorectal cells. Cancer Res 2005; 65: 3993-3997
    • (2005) Cancer Res , vol.65 , pp. 3993-3997
    • Gasche, C.1    Goel, A.2    Natarajan, L.3    Boland, C.R.4
  • 28
    • 33846231453 scopus 로고    scopus 로고
    • 5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint
    • Luciani MG, Campregher C, Fortune JM, Kunkel TA, Gasche C. 5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint. Gastroenterology 2007; 132: 221-235
    • (2007) Gastroenterology , vol.132 , pp. 221-235
    • Luciani, M.G.1    Campregher, C.2    Fortune, J.M.3    Kunkel, T.A.4    Gasche, C.5
  • 29
    • 0038445608 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs and molecular carcinogenesis of colorectal carcinomas
    • Huls G, Koornstra JJ, Kleibeuker JH. Non-steroidal anti-inflammatory drugs and molecular carcinogenesis of colorectal carcinomas. Lancet 2003; 362: 230-232
    • (2003) Lancet , vol.362 , pp. 230-232
    • Huls, G.1    Koornstra, J.J.2    Kleibeuker, J.H.3
  • 30
    • 3042788940 scopus 로고    scopus 로고
    • COX-2 inhibition and colorectal cancer
    • Koehne CH, Dubois RN. COX-2 inhibition and colorectal cancer. Semin Oncol 2004; 31: 12-21
    • (2004) Semin Oncol , vol.31 , pp. 12-21
    • Koehne, C.H.1    Dubois, R.N.2
  • 32
    • 0030952695 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential
    • Tsujii M, Kawano S, DuBois RN. Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential. Proc Natl Acad Sci USA 1997; 94: 3336-3340
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3336-3340
    • Tsujii, M.1    Kawano, S.2    DuBois, R.N.3
  • 33
    • 0141650698 scopus 로고    scopus 로고
    • Review article: The data supporting a role for aminosalicylates in the chemoprevention of colorectal cancer in patients with inflammatory bowel disease
    • Eaden J. Review article: the data supporting a role for aminosalicylates in the chemoprevention of colorectal cancer in patients with inflammatory bowel disease. Aliment Pharmacol Ther 2003; 18 Suppl 2: 15-21
    • (2003) Aliment Pharmacol Ther , vol.18 , Issue.SUPPL. 2 , pp. 15-21
    • Eaden, J.1
  • 35
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis P. Wnt signaling and cancer. Genes Dev 2000; 14: 1837-1851
    • (2000) Genes Dev , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 36
    • 5444265502 scopus 로고    scopus 로고
    • The Wnt connection to tumorigenesis
    • Behrens J, Lustig B. The Wnt connection to tumorigenesis. Int J Dev Biol 2004; 48: 477-487
    • (2004) Int J Dev Biol , vol.48 , pp. 477-487
    • Behrens, J.1    Lustig, B.2
  • 37
  • 38
    • 0030779038 scopus 로고    scopus 로고
    • Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin
    • Orford K, Crockett C, Jensen JP, Weissman AM, Byers SW. Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin. J Biol Chem 1997; 272: 24735-24738
    • (1997) J Biol Chem , vol.272 , pp. 24735-24738
    • Orford, K.1    Crockett, C.2    Jensen, J.P.3    Weissman, A.M.4    Byers, S.W.5
  • 39
    • 0033590172 scopus 로고    scopus 로고
    • Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways
    • Miller JR, Hocking AM, Brown JD, Moon RT. Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways. Oncogene 1999; 18: 7860-7872
    • (1999) Oncogene , vol.18 , pp. 7860-7872
    • Miller, J.R.1    Hocking, A.M.2    Brown, J.D.3    Moon, R.T.4
  • 42
    • 33845352518 scopus 로고    scopus 로고
    • Protein phosphatase 2A is required for mesalazine-dependent inhibition of Wnt/beta-catenin pathway activity
    • Bos CL, Diks SH, Hardwick JC, Walburg KV, Peppelenbosch MP, Richel DJ. Protein phosphatase 2A is required for mesalazine-dependent inhibition of Wnt/beta-catenin pathway activity. Carcinogenesis 2006; 27: 2371-2382
    • (2006) Carcinogenesis , vol.27 , pp. 2371-2382
    • Bos, C.L.1    Diks, S.H.2    Hardwick, J.C.3    Walburg, K.V.4    Peppelenbosch, M.P.5    Richel, D.J.6
  • 44
    • 84944367792 scopus 로고
    • Increased expression of the epidermal growth factor receptor on human colon carcinoma cells
    • Bradley SJ, Garfinkle G, Walker E, Salem R, Chen LB, Steele G Jr. Increased expression of the epidermal growth factor receptor on human colon carcinoma cells. Arch Surg 1986; 121: 1242-1247
    • (1986) Arch Surg , vol.121 , pp. 1242-1247
    • Bradley, S.J.1    Garfinkle, G.2    Walker, E.3    Salem, R.4    Chen, L.B.5    Steele Jr., G.6
  • 45
    • 0345098554 scopus 로고    scopus 로고
    • The epidermal growth factor receptor pathway and its inhibition as anticancer therapy
    • Janmaat ML, Giaccone G. The epidermal growth factor receptor pathway and its inhibition as anticancer therapy. Drugs Today (Barc) 2003; 39 Suppl C: 61-80
    • (2003) Drugs Today (Barc) , vol.39 , Issue.SUPPL. C , pp. 61-80
    • Janmaat, M.L.1    Giaccone, G.2
  • 46
    • 33847108489 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor (EGFR) is frequent in inflammatory bowel disease (IBD)-associated intestinal cancer
    • Svrcek M, Cosnes J, Tiret E, Bennis M, Parc Y, Flejou JF. Expression of epidermal growth factor receptor (EGFR) is frequent in inflammatory bowel disease (IBD)-associated intestinal cancer. Virchows Arch 2007; 450: 243-244
    • (2007) Virchows Arch , vol.450 , pp. 243-244
    • Svrcek, M.1    Cosnes, J.2    Tiret, E.3    Bennis, M.4    Parc, Y.5    Flejou, J.F.6
  • 48
    • 0034988184 scopus 로고    scopus 로고
    • The epidermal growth factor receptor as a target for cancer therapy
    • Mendelsohn J. The epidermal growth factor receptor as a target for cancer therapy. Endocr Relat Cancer 2001; 8: 3-9
    • (2001) Endocr Relat Cancer , vol.8 , pp. 3-9
    • Mendelsohn, J.1
  • 49
    • 0034722889 scopus 로고    scopus 로고
    • The EGF receptor family as targets for cancer therapy
    • Mendelsohn J, Baselga J. The EGF receptor family as targets for cancer therapy. Oncogene 2000; 19: 6550-6565
    • (2000) Oncogene , vol.19 , pp. 6550-6565
    • Mendelsohn, J.1    Baselga, J.2
  • 51
    • 0032939325 scopus 로고    scopus 로고
    • Multiple positive and negative regulators of signaling by the EGF-receptor
    • Moghal N, Sternberg PW. Multiple positive and negative regulators of signaling by the EGF-receptor. Curr Opin Cell Biol 1999; 11: 190-196
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 190-196
    • Moghal, N.1    Sternberg, P.W.2
  • 53
    • 13244279846 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor expression and activation in normal human colonic epithelial cells and tubular adenomas
    • Matthiessen MW, Pedersen G, Albrektsen T, Adamsen S, Fleckner J, Brynskov J. Peroxisome proliferator-activated receptor expression and activation in normal human colonic epithelial cells and tubular adenomas. Scand J Gastroenterol 2005; 40: 198-205
    • (2005) Scand J Gastroenterol , vol.40 , pp. 198-205
    • Matthiessen, M.W.1    Pedersen, G.2    Albrektsen, T.3    Adamsen, S.4    Fleckner, J.5    Brynskov, J.6
  • 54
    • 0036117576 scopus 로고    scopus 로고
    • Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells
    • Shimada T, Kojima K, Yoshiura K, Hiraishi H, Terano A. Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells. Gut 2002; 50: 658-664
    • (2002) Gut , vol.50 , pp. 658-664
    • Shimada, T.1    Kojima, K.2    Yoshiura, K.3    Hiraishi, H.4    Terano, A.5
  • 55
    • 0035866756 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in rats
    • Tanaka T, Kohno H, Yoshitani S, Takashima S, Okumura A, Murakami A, Hosokawa M. Ligands for peroxisome proliferator-activated receptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in rats. Cancer Res 2001; 61: 2424-2428
    • (2001) Cancer Res , vol.61 , pp. 2424-2428
    • Tanaka, T.1    Kohno, H.2    Yoshitani, S.3    Takashima, S.4    Okumura, A.5    Murakami, A.6    Hosokawa, M.7
  • 58
    • 29444449618 scopus 로고    scopus 로고
    • Repression of beta-catenin function in malignant cells by nonsteroidal antiinflammatory drugs
    • Lu D, Cottam HB, Corr M, Carson DA. Repression of beta-catenin function in malignant cells by nonsteroidal antiinflammatory drugs. Proc Natl Acad Sci USA 2005; 102: 18567-18571
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 18567-18571
    • Lu, D.1    Cottam, H.B.2    Corr, M.3    Carson, D.A.4
  • 60
    • 33747620510 scopus 로고    scopus 로고
    • Review article: Mode of action and delivery of 5-aminosalicylic acid - new evidence
    • Desreumaux P, Ghosh S. Review article: mode of action and delivery of 5-aminosalicylic acid - new evidence. Aliment Pharmacol Ther 2006; 24 Suppl 1: 2-9
    • (2006) Aliment Pharmacol Ther , vol.24 , Issue.SUPPL. 1 , pp. 2-9
    • Desreumaux, P.1    Ghosh, S.2


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