Glucocorticoid receptor antagonism augments fluoxetine-induced downregulation of the 5-HT transporter

Neuropsychopharmacology

Volumn 34, Issue 2, 2009, Pages 399-409

  Johnson, Daniel Anthony ^a   Ingram, Colin David ^a   Grant, Emma Jane ^b   Craighead, Mark ^b   Gartside, Sarah Elizabeth ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

5 HT transporter; 5 HT1A receptor; Glucocorticoid receptor antagonist; In situ hybridization histochemistry; Radioligand binding; Selective serotonin reuptake inhibitor

Indexed keywords

AUTORECEPTOR; FLUOXETINE; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR ANTAGONIST; MESSENGER RNA; ORG 34850; SEROTONIN; SEROTONIN 1A RECEPTOR; SEROTONIN TRANSPORTER; TRYPTOPHAN HYDROXYLASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DEPRESSION; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; DRUG RESPONSE; HIPPOCAMPUS; MALE; MESENCEPHALON; NEUROTRANSMISSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANALYSIS OF VARIANCE; ANIMALS; AUTORADIOGRAPHY; BRAIN; CITALOPRAM; DENSITOMETRY; DOWN-REGULATION; FLUOXETINE; IN SITU HYBRIDIZATION; MALE; RATS; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTORS, GLUCOCORTICOID; RNA, MESSENGER; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SEROTONIN UPTAKE INHIBITORS; STEROIDS; SULFONES; TRITIUM; TRYPTOPHAN HYDROXYLASE;

EID: 57849127923     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2008.70     Document Type: Article

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