-
1
-
-
1242272750
-
The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology
-
H. Daniel G. Kottra 2004 The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology Pflugers Arch. 447 610 618
-
(2004)
Pflugers Arch.
, vol.447
, pp. 610-618
-
-
Daniel, H.1
Kottra, G.2
-
2
-
-
0037380335
-
Current perspectives on established and putative mammalian oligopeptide transporters
-
D. Herrera-Ruiz G.T. Knipp 2003 Current perspectives on established and putative mammalian oligopeptide transporters J. Pharm. Sci. 92 691 714
-
(2003)
J. Pharm. Sci.
, vol.92
, pp. 691-714
-
-
Herrera-Ruiz, D.1
Knipp, G.T.2
-
3
-
-
0028333611
-
Expression cloning of a mammalian proton-coupled oligopeptide transporter
-
Y. J. Fei Y. Kanai S. Nussberger V. Ganapathy F. H. Leibach M. F. Romero S. K. Singh W. F. Boron M. A. Hediger 1994 Expression cloning of a mammalian proton-coupled oligopeptide transporter Nature 368 563 566
-
(1994)
Nature
, vol.368
, pp. 563-566
-
-
Fei, Y.J.1
Kanai, Y.2
Nussberger, S.3
Ganapathy, V.4
Leibach, F.H.5
Romero, M.F.6
Singh, S.K.7
Boron, W.F.8
Hediger, M.A.9
-
6
-
-
0029036084
-
Molecular cloning of PEPT 2, a new member of the H+/peptide cotransporter family, from human kidney
-
W. Liu R. Liang S. Ramamoorthy Y. J. Fei M. E. Ganapathy M. A. Hediger V. Ganapathy F. H. Leibach 1995 Molecular cloning of PEPT 2, a new member of the H+/peptide cotransporter family, from human kidney Biochim. Biophys. Acta 1235 461 466
-
(1995)
Biochim. Biophys. Acta
, vol.1235
, pp. 461-466
-
-
Liu, W.1
Liang, R.2
Ramamoorthy, S.3
Fei, Y.J.4
Ganapathy, M.E.5
Hediger, M.A.6
Ganapathy, V.7
Leibach, F.H.8
-
7
-
-
0034710819
-
Cloning and characterization of the gene encoding the mouse peptide transporter PEPT2
-
I. Rubio-Aliaga M. Boll H. Daniel 2000 Cloning and characterization of the gene encoding the mouse peptide transporter PEPT2 Biochem. Biophys. Res. Commun. 276 734 741
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.276
, pp. 734-741
-
-
Rubio-Aliaga, I.1
Boll, M.2
Daniel, H.3
-
9
-
-
0033659819
-
Physiological and pharmacological implications of peptide transporters, PEPT1 and PEPT2
-
Suppl 6
-
K. Inui T. Terada S. Masuda H. Saito 2000 Physiological and pharmacological implications of peptide transporters, PEPT1 and PEPT2 Nephrol. Dial. Transplant. 15 Suppl 6 11 13
-
(2000)
Nephrol. Dial. Transplant.
, vol.15
, pp. 11-13
-
-
Inui, K.1
Terada, T.2
Masuda, S.3
Saito, H.4
-
10
-
-
25644448895
-
Role and relevance of peptide transporter 2 (PEPT2) in the kidney and choroid plexus: In vivo studies with glycylsarcosine in wild-type and PEPT2 knockout mice
-
S.M. Ocheltree H. Shen Y. Hu R.F. Keep D.E. Smith 2005 Role and relevance of peptide transporter 2 (PEPT2) in the kidney and choroid plexus: in vivo studies with glycylsarcosine in wild-type and PEPT2 knockout mice J. Pharmacol. Exp. Ther. 315 240 247
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.315
, pp. 240-247
-
-
Ocheltree, S.M.1
Shen, H.2
Hu, Y.3
Keep, R.F.4
Smith, D.E.5
-
11
-
-
34250738921
-
Impact of genetic knockout of PEPT2 on cefadroxil pharmacokinetics, renal tubular reabsorption and brain penetration in mice
-
H. Shen S.M. Ocheltree Y. Hu R.F. Keep D.E. Smith 2007 Impact of genetic knockout of PEPT2 on cefadroxil pharmacokinetics, renal tubular reabsorption and brain penetration in mice Drug Metab. Dispos. 35 1209 1216
-
(2007)
Drug Metab. Dispos.
, vol.35
, pp. 1209-1216
-
-
Shen, H.1
Ocheltree, S.M.2
Hu, Y.3
Keep, R.F.4
Smith, D.E.5
-
13
-
-
0030892082
-
Cloning and functional expression of a brain peptide/histidine transporter
-
T. Yamashita S. Shimada W. Guo K. Sato E. Kohmura T. Hayakawa T. Takagi M. Tohyama 1997 Cloning and functional expression of a brain peptide/histidine transporter J. Biol. Chem. 272 10205 10211
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 10205-10211
-
-
Yamashita, T.1
Shimada, S.2
Guo, W.3
Sato, K.4
Kohmura, E.5
Hayakawa, T.6
Takagi, T.7
Tohyama, M.8
-
15
-
-
0033042420
-
Functional characteristics of basolateral peptide transporter in the human intestinal cell line Caco-2
-
T. Terada K. Sawada H. Saito Y. Hashimoto K. Inui 1999 Functional characteristics of basolateral peptide transporter in the human intestinal cell line Caco-2 Am. J. Physiol. 276 G1435 G1441
-
(1999)
Am. J. Physiol.
, vol.276
-
-
Terada, T.1
Sawada, K.2
Saito, H.3
Hashimoto, Y.4
Inui, K.5
-
17
-
-
11944257758
-
Efflux properties of basolateral peptide transporter in human intestinal cell line Caco-2
-
M. Irie T. Terada M. Okuda K. Inui 2004 Efflux properties of basolateral peptide transporter in human intestinal cell line Caco-2 Pflugers Arch. 449 186 194
-
(2004)
Pflugers Arch.
, vol.449
, pp. 186-194
-
-
Irie, M.1
Terada, T.2
Okuda, M.3
Inui, K.4
-
18
-
-
0035174680
-
Distinct transport characteristics of basolateral peptide transporters between MDCK and Caco-2 cells
-
K. Sawada T. Terada H. Saito K. Inui 2001 Distinct transport characteristics of basolateral peptide transporters between MDCK and Caco-2 cells Pflugers Arch. 443 31 37
-
(2001)
Pflugers Arch.
, vol.443
, pp. 31-37
-
-
Sawada, K.1
Terada, T.2
Saito, H.3
Inui, K.4
-
19
-
-
0024788706
-
Carnosine, homocarnosine and anserine: Could they act as antioxidants in vivo?
-
O. I. Aruoma M. J. Laughton B. Halliwell 1989 Carnosine, homocarnosine and anserine: could they act as antioxidants in vivo? Biochem. J. 264 863 869
-
(1989)
Biochem. J.
, vol.264
, pp. 863-869
-
-
Aruoma, O.I.1
Laughton, M.J.2
Halliwell, B.3
-
20
-
-
0025032997
-
Scavenging of singlet molecular oxygen by imidazole compounds: High and sustained activities of carboxy terminal histidine dipeptides and exceptional activity of imidazole-4-acetic acid
-
P. E. Hartman Z. Hartman K. T. Ault 1990 Scavenging of singlet molecular oxygen by imidazole compounds: high and sustained activities of carboxy terminal histidine dipeptides and exceptional activity of imidazole-4-acetic acid Photochem. Photobiol. 51 59 66
-
(1990)
Photochem. Photobiol.
, vol.51
, pp. 59-66
-
-
Hartman, P.E.1
Hartman, Z.2
Ault, K.T.3
-
21
-
-
0032408416
-
Pluripotent protective effects of carnosine, a naturally occurring dipeptide
-
A. R. Hipkiss J. E. Preston D. T. Himsworth V. C. Worthingtun M. Keown J. Michaelis J. Lawrence A. Mateen L. Allende P. A. Eagles N. J. Abbott 1998 Pluripotent protective effects of carnosine, a naturally occurring dipeptide Ann. N. Y. Acad. Sci. 854 37 53
-
(1998)
Ann. N. Y. Acad. Sci.
, vol.854
, pp. 37-53
-
-
Hipkiss, A.R.1
Preston, J.E.2
Himsworth, D.T.3
Worthingtun, V.C.4
Keown, M.5
Michaelis, J.6
Lawrence, J.7
Mateen, A.8
Allende, L.9
Eagles, P.A.10
Abbott, N.J.11
-
22
-
-
0032146427
-
Carnosine, a protective, anti-ageing peptide?
-
A. R. Hipkiss 1998 Carnosine, a protective, anti-ageing peptide? Int. J. Biochem. Cell Biol. 30 863 868
-
(1998)
Int. J. Biochem. Cell Biol.
, vol.30
, pp. 863-868
-
-
Hipkiss, A.R.1
-
23
-
-
23644445372
-
Carnosine as a protective factor in diabetic nephropathy: Association with a leucine repeat of the carnosinase gene CNDP1
-
B. Janssen D. Hohenadel P. Brinkkoetter V. Peters N. Rind C. Fischer I. Rychlik M. Cerna M. Romzova E. de Heer H. Baelde S. J. Bakker M. Zirie E. Rondeau P. Mathieson M. A. Saleem J. Meyer H. Koppel S. Sauerhoefer C. R. Bartram P. Nawroth H. P. Hammes B. A. Yard J. Zschocke F. J. van der Woude 2005 Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1 Diabetes 54 2320 2327
-
(2005)
Diabetes
, vol.54
, pp. 2320-2327
-
-
Janssen, B.1
Hohenadel, D.2
Brinkkoetter, P.3
Peters, V.4
Rind, N.5
Fischer, C.6
Rychlik, I.7
Cerna, M.8
Romzova, M.9
De Heer, E.10
Baelde, H.11
Bakker, S.J.12
Zirie, M.13
Rondeau, E.14
Mathieson, P.15
Saleem, M.A.16
Meyer, J.17
Koppel, H.18
Sauerhoefer, S.19
Bartram, C.R.20
Nawroth, P.21
Hammes, H.P.22
Yard, B.A.23
Zschocke, J.24
Van Der Woude, F.J.25
more..
-
24
-
-
0142102340
-
Preventive effect of L-carnosine on ischemia/reperfusion-induced acute renal failure in rats
-
T. Fujii M. Takaoka T. Muraoka H. Kurata N. Tsuruoka H. Ono Y. Kiso T. Tanaka Y. Matsumura 2003 Preventive effect of L-carnosine on ischemia/reperfusion-induced acute renal failure in rats Eur. J. Pharmacol. 474 261 267
-
(2003)
Eur. J. Pharmacol.
, vol.474
, pp. 261-267
-
-
Fujii, T.1
Takaoka, M.2
Muraoka, T.3
Kurata, H.4
Tsuruoka, N.5
Ono, H.6
Kiso, Y.7
Tanaka, T.8
Matsumura, Y.9
-
26
-
-
33751199388
-
Renoprotective effects of l-carnosine on ischemia/reperfusion-induced renal injury in rats
-
H. Kurata T. Fujii H. Tsutsui T. Katayama M. Ohkita M. Takaoka N. Tsuruoka Y. Kiso Y. Ohno Y. Fujisawa T. Shokoji A. Nishiyama Y. Abe Y. Matsumura 2006 Renoprotective effects of l-carnosine on ischemia/reperfusion-induced renal injury in rats J. Pharmacol. Exp. Ther. 319 640 647
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.319
, pp. 640-647
-
-
Kurata, H.1
Fujii, T.2
Tsutsui, H.3
Katayama, T.4
Ohkita, M.5
Takaoka, M.6
Tsuruoka, N.7
Kiso, Y.8
Ohno, Y.9
Fujisawa, Y.10
Shokoji, T.11
Nishiyama, A.12
Abe, Y.13
Matsumura, Y.14
-
27
-
-
16444383510
-
Characterization of carnosine uptake and its physiological function in human intestinal epithelial Caco-2 cells
-
D. O. Son H. Satsu Y. Kiso M. Shimizu 2004 Characterization of carnosine uptake and its physiological function in human intestinal epithelial Caco-2 cells Biofactors 21 395 398
-
(2004)
Biofactors
, vol.21
, pp. 395-398
-
-
Son, D.O.1
Satsu, H.2
Kiso, Y.3
Shimizu, M.4
-
28
-
-
1942487737
-
Carnosine uptake in rat choroid plexus primary cell cultures and choroid plexus whole tissue from PEPT2 null mice
-
N. S. Teuscher H. Shen C. Shu J. Xiang R. F. Keep D. E. Smith 2004 Carnosine uptake in rat choroid plexus primary cell cultures and choroid plexus whole tissue from PEPT2 null mice J. Neurochem. 89 375 382
-
(2004)
J. Neurochem.
, vol.89
, pp. 375-382
-
-
Teuscher, N.S.1
Shen, H.2
Shu, C.3
Xiang, J.4
Keep, R.F.5
Smith, D.E.6
-
29
-
-
33644834859
-
The functional evaluation of human peptide/histidine transporter 1 (hPHT1) in transiently transfected COS-7 cells
-
R. K. Bhardwaj D. Herrera-Ruiz N. Eltoukhy M. Saad G. T. Knipp 2006 The functional evaluation of human peptide/histidine transporter 1 (hPHT1) in transiently transfected COS-7 cells Eur. J. Pharm. Sci. 27 533 542
-
(2006)
Eur. J. Pharm. Sci.
, vol.27
, pp. 533-542
-
-
Bhardwaj, R.K.1
Herrera-Ruiz, D.2
Eltoukhy, N.3
Saad, M.4
Knipp, G.T.5
-
30
-
-
0034825921
-
Mechanism of intestinal absorption and renal reabsorption of an orally active ACE inhibitor: Uptake and transport of fosinopril in cell cultures
-
C. Shu H. Shen U. Hopfer D. E. Smith 2001 Mechanism of intestinal absorption and renal reabsorption of an orally active ACE inhibitor: uptake and transport of fosinopril in cell cultures Drug Metab. Dispos. 29 1307 1315
-
(2001)
Drug Metab. Dispos.
, vol.29
, pp. 1307-1315
-
-
Shu, C.1
Shen, H.2
Hopfer, U.3
Smith, D.E.4
-
31
-
-
0033943308
-
Functional evidence for presence of PEPT2 in rat choroid plexus: Studies with glycylsarcosine
-
N. S. Teuscher A. Novotny R. F. Keep D. E. Smith 2000 Functional evidence for presence of PEPT2 in rat choroid plexus: studies with glycylsarcosine J. Pharmacol. Exp. Ther. 294 494 499
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.294
, pp. 494-499
-
-
Teuscher, N.S.1
Novotny, A.2
Keep, R.F.3
Smith, D.E.4
-
32
-
-
0036260702
-
Role of PEPT2 in peptide/mimetic trafficking at the blood-cerebrospinal fluid barrier: Studies in rat choroid plexus epithelial cells in primary culture
-
C. Shu H. Shen N. S. Teuscher P. J. Lorenzi R. F. Keep D. E. Smith 2002 Role of PEPT2 in peptide/mimetic trafficking at the blood-cerebrospinal fluid barrier: studies in rat choroid plexus epithelial cells in primary culture J. Pharmacol. Exp. Ther. 301 820 829
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.301
, pp. 820-829
-
-
Shu, C.1
Shen, H.2
Teuscher, N.S.3
Lorenzi, P.J.4
Keep, R.F.5
Smith, D.E.6
-
33
-
-
0016562984
-
A method using 3-O-methyl-D-glucose and phloretin for the determination of intracellular water space of cells in monolayer culture
-
R. F. Kletzien M. W. Pariza J. E. Becker V. R. Potter 1975 A method using 3-O-methyl-D-glucose and phloretin for the determination of intracellular water space of cells in monolayer culture Anal. Biochem. 68 537 544
-
(1975)
Anal. Biochem.
, vol.68
, pp. 537-544
-
-
Kletzien, R.F.1
Pariza, M.W.2
Becker, J.E.3
Potter, V.R.4
-
35
-
-
37549046023
-
Permeability, transport, and metabolism of solutes in Caco-2 cell monolayers: A theoretical study
-
H. Sun K. S. Pang 2008 Permeability, transport, and metabolism of solutes in Caco-2 cell monolayers: A theoretical study Drug Metab. Dispos. 35 102 123
-
(2008)
Drug Metab. Dispos.
, vol.35
, pp. 102-123
-
-
Sun, H.1
Pang, K.S.2
-
36
-
-
0036744803
-
Transport characteristics of L-carnosine and the anticancer derivative 4-toluenesulfonylureido-carnosine in a human epithelial cell line
-
C. U. Nielsen C. T. Supuran A. Scozzafava S. Frokjaer B. Steffansen B. Brodin 2002 Transport characteristics of L-carnosine and the anticancer derivative 4-toluenesulfonylureido-carnosine in a human epithelial cell line Pharm. Res. 19 1337 1344
-
(2002)
Pharm. Res.
, vol.19
, pp. 1337-1344
-
-
Nielsen, C.U.1
Supuran, C.T.2
Scozzafava, A.3
Frokjaer, S.4
Steffansen, B.5
Brodin, B.6
-
37
-
-
23844467052
-
Characterization of rPEPT2-mediated Gly-Sar transport parameters in the rat kidney proximal tubule cell line SKPT-0193 cl.2 cultured in basic growth media
-
S. A. Bravo C. U. Nielsen S. Frokjaer B. Brodin 2005 Characterization of rPEPT2-mediated Gly-Sar transport parameters in the rat kidney proximal tubule cell line SKPT-0193 cl.2 cultured in basic growth media Mol. Pharmaceutics 2 98 108
-
(2005)
Mol. Pharmaceutics
, vol.2
, pp. 98-108
-
-
Bravo, S.A.1
Nielsen, C.U.2
Frokjaer, S.3
Brodin, B.4
-
38
-
-
2442688922
-
Transport of the phosphonodipeptide alafosfalin by the H+/peptide cotransporters PEPT1 and PEPT2 in intestinal and renal epithelial cells
-
J. Neumann M. Bruch S. Gebauer M. Brandsch 2004 Transport of the phosphonodipeptide alafosfalin by the H+/peptide cotransporters PEPT1 and PEPT2 in intestinal and renal epithelial cells Eur. J. Biochem. 271 2012 2017
-
(2004)
Eur. J. Biochem.
, vol.271
, pp. 2012-2017
-
-
Neumann, J.1
Bruch, M.2
Gebauer, S.3
Brandsch, M.4
-
39
-
-
0028808099
-
Identification of a renal cell line that constitutively expresses the kidney-specific high-affinity H+/peptide cotransporter
-
M. Brandsch C. Brandsch P. D. Prasad V. Ganapathy U. Hopfer F. H. Leibach 1995 Identification of a renal cell line that constitutively expresses the kidney-specific high-affinity H+/peptide cotransporter FASEB J. 9 1489 1496
-
(1995)
FASEB J.
, vol.9
, pp. 1489-1496
-
-
Brandsch, M.1
Brandsch, C.2
Prasad, P.D.3
Ganapathy, V.4
Hopfer, U.5
Leibach, F.H.6
-
40
-
-
0028826927
-
Differential recognition of beta-lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2
-
M. E. Ganapathy M. Brandsch P. D. Prasad V. Ganapathy F. H. Leibach 1995 Differential recognition of beta-lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2 J. Biol. Chem. 270 25672 25677
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25672-25677
-
-
Ganapathy, M.E.1
Brandsch, M.2
Prasad, P.D.3
Ganapathy, V.4
Leibach, F.H.5
-
41
-
-
0942279631
-
Epidermal growth factor decreases PEPT2 transport capacity and expression in the rat kidney proximal tubule cell line SKPT0193 cl.2
-
S. A. Bravo C. U. Nielsen J. Amstrup S. Frokjaer B. Brodin 2004 Epidermal growth factor decreases PEPT2 transport capacity and expression in the rat kidney proximal tubule cell line SKPT0193 cl.2 Am. J. Physiol. Renal. Physiol. 286 F385 F393
-
(2004)
Am. J. Physiol. Renal. Physiol.
, vol.286
-
-
Bravo, S.A.1
Nielsen, C.U.2
Amstrup, J.3
Frokjaer, S.4
Brodin, B.5
-
43
-
-
0030892709
-
Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2
-
M. E. Ganapathy P. D. Prasad B. Mackenzie V. Ganapathy F. H. Leibach 1997 Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2 Biochim. Biophys. Acta 1324 296 308
-
(1997)
Biochim. Biophys. Acta
, vol.1324
, pp. 296-308
-
-
Ganapathy, M.E.1
Prasad, P.D.2
MacKenzie, B.3
Ganapathy, V.4
Leibach, F.H.5
-
44
-
-
0030964451
-
Influence of proton and essential histidyl residues on the transport kinetics of the H+/peptide cotransport systems in intestine (PEPT 1) and kidney (PEPT 2)
-
M. Brandsch C. Brandsch M. E. Ganapathy C. S. Chew V. Ganapathy F. H. Leibach 1997 Influence of proton and essential histidyl residues on the transport kinetics of the H+/peptide cotransport systems in intestine (PEPT 1) and kidney (PEPT 2) Biochim. Biophys. Acta 1324 251 262
-
(1997)
Biochim. Biophys. Acta
, vol.1324
, pp. 251-262
-
-
Brandsch, M.1
Brandsch, C.2
Ganapathy, M.E.3
Chew, C.S.4
Ganapathy, V.5
Leibach, F.H.6
-
45
-
-
0033812228
-
Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2
-
M. Sugawara W. Huang Y. J. Fei F. H. Leibach V. Ganapathy M. E. Ganapathy 2000 Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2 J. Pharm. Sci. 89 781 789
-
(2000)
J. Pharm. Sci.
, vol.89
, pp. 781-789
-
-
Sugawara, M.1
Huang, W.2
Fei, Y.J.3
Leibach, F.H.4
Ganapathy, V.5
Ganapathy, M.E.6
-
46
-
-
0034858814
-
PEPT2-mediated uptake of neuropeptides in rat choroid plexus
-
N. S. Teuscher R. F. Keep D. E. Smith 2001 PEPT2-mediated uptake of neuropeptides in rat choroid plexus Pharm. Res. 18 807 813
-
(2001)
Pharm. Res.
, vol.18
, pp. 807-813
-
-
Teuscher, N.S.1
Keep, R.F.2
Smith, D.E.3
-
47
-
-
33750711999
-
PEPT2-mediated transport of 5-aminolevulinic acid and carnosine in astrocytes
-
J. Xiang Y. Hu D. E. Smith R. F. Keep 2006 PEPT2-mediated transport of 5-aminolevulinic acid and carnosine in astrocytes Brain Res. 1122 18 23
-
(2006)
Brain Res.
, vol.1122
, pp. 18-23
-
-
Xiang, J.1
Hu, Y.2
Smith, D.E.3
Keep, R.F.4
-
48
-
-
1442351172
-
Peptide transporters: Structure, function, regulation and application for drug delivery
-
T. Terada K. Inui 2004 Peptide transporters: structure, function, regulation and application for drug delivery Curr. Drug Metab. 5 85 94
-
(2004)
Curr. Drug Metab.
, vol.5
, pp. 85-94
-
-
Terada, T.1
Inui, K.2
-
49
-
-
0022907968
-
Studies of kidney cells in culture
-
J. S. Handler 1986 Studies of kidney cells in culture Kidney Int. 30 208 215
-
(1986)
Kidney Int.
, vol.30
, pp. 208-215
-
-
Handler, J.S.1
|