메뉴 건너뛰기




Volumn 271, Issue 10, 2004, Pages 2012-2017

Transport of the phosphonodipeptide alafosfalin by the H +/peptide cotransporters PEPT1 and PEPT2 in intestinal and renal epithelial cells

Author keywords

Alafosfalin; Alaphosphin; Caco 2 cells; SKPT cells; Ussing technique

Indexed keywords

ALAFOSFALIN; CARBON 14; GLYCYLSARCOSINE; MANNITOL; PEPTIDE TRANSPORTER 1; PEPTIDE TRANSPORTER 2; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

EID: 2442688922     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.2004.04114.x     Document Type: Article
Times cited : (36)

References (31)
  • 2
    • 0020322531 scopus 로고
    • In vitro potentiation of cephalosporins by alafosfalin against urinary tract bacteria
    • Arisawa, M., Ohshima, J., Ohsawa, E. & Maruyama, H.B. (1982) In vitro potentiation of cephalosporins by alafosfalin against urinary tract bacteria. Antimicrob. Agents Chemother. 21, 706-710.
    • (1982) Antimicrob. Agents Chemother. , vol.21 , pp. 706-710
    • Arisawa, M.1    Ohshima, J.2    Ohsawa, E.3    Maruyama, H.B.4
  • 3
    • 2442668263 scopus 로고
    • Activity of alafosfalin against bacterial pathogens of the gastrointestinal tract in vitro and in vivo. Current chemotherapy and immunotherapy
    • Westmacott, D., Hall, M., Hassall, C., Lees, L., Rowe, B. & Ward, L. (1982) Activity of alafosfalin against bacterial pathogens of the gastrointestinal tract in vitro and in vivo. Current chemotherapy and immunotherapy: Proceedings 12th Int. Congr. Chemother. 1, 340-342.
    • (1982) Proceedings 12th Int. Congr. Chemother. , vol.1 , pp. 340-342
    • Westmacott, D.1    Hall, M.2    Hassall, C.3    Lees, L.4    Rowe, B.5    Ward, L.6
  • 4
    • 0018689189 scopus 로고
    • Alafosfalin, a new inhibitor of cell wall biosynthesis: In vitro activity against urinary isolates in Japan and potentiation with β-lactams
    • Maruyama, H.B., Arisawa, M. & Sawada, T. (1979) Alafosfalin, a new inhibitor of cell wall biosynthesis: in vitro activity against urinary isolates in Japan and potentiation with β-lactams. Antimicrob. Agents Chemother. 16, 444-451.
    • (1979) Antimicrob. Agents Chemother. , vol.16 , pp. 444-451
    • Maruyama, H.B.1    Arisawa, M.2    Sawada, T.3
  • 6
    • 0018843233 scopus 로고
    • Effect of food on the bioavailability of alafosfalin, a new antibacterial agent
    • Welling, P.G., Kendall, M.J. & Dean, S. (1980) Effect of food on the bioavailability of alafosfalin, a new antibacterial agent. J. Antimicrob. Chemother. 6, 373-379.
    • (1980) J. Antimicrob. Chemother. , vol.6 , pp. 373-379
    • Welling, P.G.1    Kendall, M.J.2    Dean, S.3
  • 7
  • 9
    • 2442674547 scopus 로고    scopus 로고
    • Druggan, P. (2002) Improvements in or relating to selective agents for biological cultures. PCT International Application Patent no. WO022785.
    • (2002)
    • Druggan, P.1
  • 11
    • 0020323723 scopus 로고
    • The characteristics of peptide uptake in Streptococcus faecalis: Studies on the transport of natural peptides and antibacterial phosphonopeptides
    • Nisbet, T.M. & Payne, J.W. (1982) The characteristics of peptide uptake in Streptococcus faecalis: studies on the transport of natural peptides and antibacterial phosphonopeptides. J. Gen. Microbiol. 128, 1357-1364.
    • (1982) J. Gen. Microbiol. , vol.128 , pp. 1357-1364
    • Nisbet, T.M.1    Payne, J.W.2
  • 13
    • 0021833705 scopus 로고
    • Activity of a peptidyl prodrug, alafosfalin, against anaerobic bacteria
    • Grappel, S.F., Giovenella, A.J. & Nisbet, L.J. (1985) Activity of a peptidyl prodrug, alafosfalin, against anaerobic bacteria. Antimicrob. Agents Chemother. 27, 961-963.
    • (1985) Antimicrob. Agents Chemother. , vol.27 , pp. 961-963
    • Grappel, S.F.1    Giovenella, A.J.2    Nisbet, L.J.3
  • 14
    • 0025469191 scopus 로고
    • Simultaneous exploitation of different peptide permeases by combinations of synthetic peptide smugglins can lead to enhanced antibacterial activity
    • Smith, M.W. & Payne, J.W. (1990) Simultaneous exploitation of different peptide permeases by combinations of synthetic peptide smugglins can lead to enhanced antibacterial activity. FEMS Microbiol. Lett. 58, 311-316.
    • (1990) FEMS Microbiol. Lett. , vol.58 , pp. 311-316
    • Smith, M.W.1    Payne, J.W.2
  • 15
    • 0036710840 scopus 로고    scopus 로고
    • Mammalian peptide transporters as targets for drug delivery
    • Rubio-Aliaga, I. & Daniel, H. (2002) Mammalian peptide transporters as targets for drug delivery. Trends Pharmacol. Sci. 23, 434-440.
    • (2002) Trends Pharmacol. Sci. , vol.23 , pp. 434-440
    • Rubio-Aliaga, I.1    Daniel, H.2
  • 18
    • 1242272750 scopus 로고    scopus 로고
    • The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology
    • Daniel, H. & Kottra, G. (2004) The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology. Pflugers Arch. 447, 610-618.
    • (2004) Pflugers Arch. , vol.447 , pp. 610-618
    • Daniel, H.1    Kottra, G.2
  • 19
    • 0036018543 scopus 로고    scopus 로고
    • Transport of peptidomimetic drugs by the intestinal di/tri-peptide transporter, PepT1
    • Brodin, B., Nielsen, C.U., Steffansen, B. & Frokjaer, S. (2002) Transport of peptidomimetic drugs by the intestinal di/tri-peptide transporter, PepT1. Pharmacol. Toxicol. 90, 285-296.
    • (2002) Pharmacol. Toxicol. , vol.90 , pp. 285-296
    • Brodin, B.1    Nielsen, C.U.2    Steffansen, B.3    Frokjaer, S.4
  • 20
    • 0040699988 scopus 로고    scopus 로고
    • +/peptide symporter (PEPT1), the uptake into Caco-2 cell monolayers and the transepithelial flux
    • +/peptide symporter (PEPT1), the uptake into Caco-2 cell monolayers and the transepithelial flux. Pharm. Res. 16, 55-61.
    • (1999) Pharm. Res. , vol.16 , pp. 55-61
    • Bretschneider, B.1    Brandsch, M.2    Neubert, R.3
  • 22
    • 0028826927 scopus 로고
    • Differential recognition of β-lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2
    • Ganapathy, M.E., Brandsch, M., Prasad, P.D., Ganapathy, V. & Leibach, F.H. (1995) Differential recognition of β-lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2. J. Biol. Chem. 270, 25672-25677.
    • (1995) J. Biol. Chem. , vol.270 , pp. 25672-25677
    • Ganapathy, M.E.1    Brandsch, M.2    Prasad, P.D.3    Ganapathy, V.4    Leibach, F.H.5
  • 23
    • 0037380039 scopus 로고    scopus 로고
    • δ-Aminolevulinic acid transport in cancer cells of the human extrahepatic biliary duct
    • Neumann, J. & Brandsch, M. (2003) δ-Aminolevulinic acid transport in cancer cells of the human extrahepatic biliary duct. J. Pharmacol. Exp. Ther. 305, 219-224.
    • (2003) J. Pharmacol. Exp. Ther. , vol.305 , pp. 219-224
    • Neumann, J.1    Brandsch, M.2
  • 25
    • 0034825921 scopus 로고    scopus 로고
    • Mechanism of intestinal absorption and renal reabsorption of an orally active ace inhibitor: Uptake and transport of fosinopril in cell cultures
    • Shu, C., Shen, H., Hopfer, U. & Smith, D.E. (2001) Mechanism of intestinal absorption and renal reabsorption of an orally active ace inhibitor: uptake and transport of fosinopril in cell cultures. Drug Metab. Dispos. 29, 1307-1315.
    • (2001) Drug Metab. Dispos. , vol.29 , pp. 1307-1315
    • Shu, C.1    Shen, H.2    Hopfer, U.3    Smith, D.E.4
  • 29
    • 0027482022 scopus 로고
    • Transepithelial dipeptide (glycylsarcosine) transport across epithelial monolayers of human Caco-2 cells is rheogenic
    • Thwaites, D.T., McEwan, G.T.A., Hirst, B.H. & Simmons, N.L. (1993) Transepithelial dipeptide (glycylsarcosine) transport across epithelial monolayers of human Caco-2 cells is rheogenic. Pflügers Arch. 425, 178-180.
    • (1993) Pflügers Arch. , vol.425 , pp. 178-180
    • Thwaites, D.T.1    McEwan, G.T.A.2    Hirst, B.H.3    Simmons, N.L.4
  • 31
    • 0033042420 scopus 로고    scopus 로고
    • Functional characteristics of basolateral peptide transporter in the human intestinal cell line Caco-2
    • Terada, T., Sawada, K., Saito, H., Hashimoto, Y. & Inui, K. (1999) Functional characteristics of basolateral peptide transporter in the human intestinal cell line Caco-2. Am. J. Physiol. 276, G1435-G1441.
    • (1999) Am. J. Physiol. , vol.276
    • Terada, T.1    Sawada, K.2    Saito, H.3    Hashimoto, Y.4    Inui, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.