Intracellular calcium modulation of voltage-gated sodium channels in ventricular myocytes

Cardiovascular Research

Volumn 81, Issue 1, 2009, Pages 72-81

  Casini, Simona ^a   Verkerk, Arie O ^a   Van Borren, Marcel M G J ^a   Van Ginneken, Antoni C G ^a   Veldkamp, Marieke W ^a   De Bakker, Jacques M T ^a   Tan, Hanno L ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Arrhythmia; Ion channels; Na channel

Indexed keywords

CAFFEINE; CALCIUM; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; VOLTAGE GATED SODIUM CHANNEL;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CELL DENSITY; CELL ISOLATION; CELL STIMULATION; CHANNEL GATING; CONTROLLED STUDY; ELECTRIC POTENTIAL; EMBRYO; FLOW RATE; HEART ELECTROPHYSIOLOGY; HEART FAILURE; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART MUSCLE EXCITABILITY; HEART VENTRICLE; HUMAN; HUMAN CELL; NONHUMAN; PATCH CLAMP; PIPETTE; PRIORITY JOURNAL; SODIUM CURRENT; WHOLE CELL;

ACTION POTENTIALS; ANIMALS; BUFFERS; CAFFEINE; CALCIUM; CELL LINE; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EGTAZIC ACID; HEART FAILURE; HEART RATE; HEART VENTRICLES; HOMEOSTASIS; HUMANS; MUSCLE PROTEINS; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; PHOSPHODIESTERASE INHIBITORS; RABBITS; SODIUM CHANNELS; TRANSFECTION;

EID: 57749201111     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvn274     Document Type: Article

References (42)

1. Tan HL, Bink-Boelkens MT, Bezzina CR, Viswanathan PC, Beaufort-Krol GC, van Tintelen PJ et al. A sodium-channel mutation causes isolated cardiac conduction disease. Nature 2001;409:1043-1047.
2. + regulation in normal and failing hearts. J Pharmacol Sci 2006;100:315-322.
3. 2+-exchanger in heart failure. Cardiovasc Res 2003;57:986-995.
4. Brehm P, Eckert R. Calcium entry leads to inactivation of calcium channel in Paramecium. Science 1978;202:1203-1206.
5. + channels in guinea-pig ventricular cells. J Physiol 1993;470:295-311.
6. Tohse N. Calcium-sensitive delayed rectifier potassium current in guinea pig ventricular cells. Am J Physiol 1990;258:H1200-H1207.
7. Duff HJ, Offord J, West J, Catterall WA. Class I and IV antiarrhythmic drugs and cytosolic calcium regulate mRNA encoding the sodium channel a-subunit in rat cardiac muscle. Mol Pharmacol 1992;42:570-574.
8. Chiamvimonvat N, Kargacin ME, Clark RB, Duff HJ. Effects of intracellular calcium on sodium current density in cultured neonatal rat cardiac myocytes. J Physiol 1995;483:307-318.
9. French RJ, Worley JF 3rd, Wonderlin WF, Kularatna AS, Krueger BK. Ion permeation, divalent ion block, and chemical modification of single sodium channels. Description by single- and double-occupancy rate-theory models. J Gen Physiol 1994;103:447-470.
10. Zamponi GW, French RJ. Sodium current inhibition by internal calcium: a combination of open-channel block and surface charge screening? J Membr Biol 1995;147:1-6.
11. Wingo TL, Shah VN, Anderson ME, Lybrand TP, Chazin WJ, Balser JR. An EF-hand in the sodium channel couples intracellular calcium to cardiac excitability. Nat Struct Mol Biol 2004;11:219-225.
12. + channels. J Clin Invest 2006;116:3127-3138.
13. Vermeulen JT, McGuire MA, Opthof T, Coronel R, de Bakker JM, Klopping C et al. Triggered activity and automaticity in ventricular trabeculae of failing human and rabbit hearts. Cardiovasc Res 1994;28:1547-1554.
14. de Groot JR, Schumacher CA, Verkerk AO, Baartscheer A, Fiolet JW, Coronel R. Intrinsic heterogeneity in repolarization is increased in isolated failing rabbit cardiomyocytes during simulated ischemia. Cardiovasc Res 2003;59:705-714.
15. + channel. Circ Res 2000;86:E91-E97.
16. Tang JM, Wang J, Quandt FN, Eisenberg RS. Perfusing pipettes. Pflugers Arch 1990;416:347-350.
17. Na in canine cardiac Purkinje cells. Circ Res 1988;63:386-398.
18. Remme CA, Verkerk AO, Nuyens D, van Ginneken AC, van Brunschot S, Belterman CN et al. Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD. Circulation 2006;114:2584-2594.
19. Linz KW, Meyer R. Control of L-type calcium current during the action potential of guinea-pig ventricular myocytes. J Physiol 1998;513:425-442.
20. Winslow RL, Rice J, Jafri S, Marbán E, O'Rourke B. Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, II: model studies. Circ Res 1999;84:571-586.
21. + channels in guinea pig ventricular myocytes. Am J Physiol 1993;264:H454-H463.
22. 2+ block of cardiac Na channel before and during b-adrenergic stimulation. Jpn J Physiol 2001;51:679-685.
23. Casini S, Tan HL, Bhuiyan ZA, Bezzina CR, Barnett P, Cerbai E et al. Characterization of a novel SCN5A mutation associated with Brugada syndrome reveals involvement of DIIIS4-S5 linker in slow inactivation. Cardiovasc Res 2007;76:418-429.
24. 2+ store that is responsive to stop-flow medium changes and insensitive to caffeine and ryanodine. Biochem J 1999;343:39-44.
25. Nilius B. Calcium block of guinea-pig heart sodium channels with and without modification by the piperazinylindole DPI 201-106. J Physiol 1988;399:537-558.
26. Vora T, Corry B, Chung SH. A model of sodium channels. Biochim Biophys Acta 2005;1668:106-116.
27. 2+ sensitivity of sodium channels. J Biol Chem 2004;279:45004-45012.
28. Tan HL, Kupershmidt S, Zhang R, Stepanovic S, Roden DM, Wilde AA et al. A calcium sensor in the sodium channel modulates cardiac excitability. Nature 2002;415:442-447.
29. Young KA, Caldwell JH. Modulation of skeletal and cardiac voltage-gated sodium channels by calmodulin. J Physiol 2005;565:349-370.
30. 2+, calmodulin, and CaMKII in normal and failing dog cardiomyocytes: similarities and differences. Am J Physiol Heart Circ Physiol 2008;294:H1597-H1608.
31. Herzog RI, Liu C, Waxman SG, Cummins TR. Calmodulin binds to the C terminus of sodium channels Nav1.4 and Nav1.6 and differentially modulates their functional properties. J Neurosci 2003;23:8261-8270.
32. Na is in the common final pathway to heart block in murine hearts overexpressing calcineurin. Am J Physiol Heart Circ Physiol 2006;291:H2669-H2679.
33. + channels expressed in a mammalian cell line and in ventricular myocytes by protein kinase C. Proc Natl Acad Sci USA 1994;91:3289- 3293.
34. + channel. Circ Res 1997;80:370-376.
35. Maltsev VA, Sabbab HN, Undrovinas AI. Down-regulation of sodium current in chronic heart failure: effect of long-term therapy with carvedilol. Cell Mol Life Sci 2002;59:1561-1568.
36. Valdivia CR, Chu WW, Pu J, Foell JD, Haworth RA, Wolff MR et al. Increased late sodium current in myocytes from a canine heart failure model and from failing human heart. J Mol Cell Cardiol 2005;38:475-483.
37. + channel subunits in chronic heart failure. J Mol Cell Cardiol 2004;37:91-100.
38. Wiegerinck RF, Verkerk AO, Belterman CN, van Veen TA, Baartscheer A, Opthof T et al. Larger cell size in rabbits with heart failure increases myocardial conduction velocity and QRS duration. Circulation 2006; 113:806-813.
39. Kääb S, Nuss HB, Chiamvimonvat N, O'Rourke B, Pak PH, Kass DA et al. Ionic mechanism of action potential prolongation in ventricular myocytes from dogs with pacing-induced heart failure. Circ Res 1996;78:262-273.
40. Zeppenfeld K, Schalij MJ, Bleeker GB, Holman ER, Bax JJ. Acceleration-dependent left bundle branch block with severe left ventricular dyssynchrony results in acute heart failure: are there more patients who benefit from cardiac resynchronization therapy? J Cardiovasc Electrophysiol 2006;17:101-103.
41. Hofmann M, Bauer R, Handrock R, Weidinger G, Goedel-Meinen L. Prognostic value of the QRS duration in patients with heart failure: a subgroup analysis from 24 centers of Val-HeFT. J Card Fail 2005;11:523-528.
42. Iuliano S, Fisher SG, Karasik PE, Fletcher RD, Singh SN. QRS duration and mortality in patients with congestive heart failure. Am Heart J 2002;143:1085-1091.