Effects of dimethyl sulphoxide and dexamethasone on mRNA expression of myogenesis- and muscle proteolytic system-related genes in mouse myoblastic C2C12 cells

Journal of Biochemistry

Volumn 144, Issue 6, 2008, Pages 717-724

  Nishimura, Masuhiro ^a   Mikura, Mayumi ^a,b   Hirasaka, Katsuya ^b   Okumura, Yuushi ^b   Nikawa, Takeshi ^b   Kawano, Yuichi ^a   Nakayama, Mitsuo ^a   Ikeda, Muneharu ^a  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

C2C12 myotubes; Dexamethasone; Dimethyl sulphoxide; Muscle proteolytic system related genes; Myogenesis related genes

Indexed keywords

ATROGIN 1; DEXAMETHASONE; DIMETHYL SULFOXIDE; MESSENGER RNA; MUSCLE RING FINGER 1 PROTEIN; MYOGENIC FACTOR 5; MYOGENIN; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FKHRL1;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL LINE; CONCENTRATION (PARAMETERS); GENE; GENE EXPRESSION; MOUSE; MUSCLE DEVELOPMENT; MYOBLAST; MYOTUBE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DEGRADATION;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; DEXAMETHASONE; DIMETHYL SULFOXIDE; GENE EXPRESSION; MICE; MUSCLE DEVELOPMENT; MUSCLE FIBERS, SKELETAL; RNA, MESSENGER;

EID: 57749195680     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvn126     Document Type: Article

References (28)

1. Yaffe, D. and Saxel, O. (1977) Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle. Nature 270, 725-727
2. Molkentin, J.D. and Olson, E.N. (1996) Defining the regulatory networks for muscle development. Curr. Opin. Genet. Dev. 6, 445-453
3. Venuti, J.M. and Cserjesi, P. (1996) Molecular embryology of skeletal myogenesis. Curr. Top. Dev. Biol. 34, 169-206
4. Jackman, R.W. and Kandarian, S.C. (2004) The molecular basis of skeletal muscle atrophy. Am. J. Physiol. Cell Physiol. 287, C834-C843
5. te Pas, M.F., de Jong, P.R., and Verburg, F.J. (2000) Glucocorticoid inhibition of C2C12 proliferation rate and differentiation capacity in relation to mRNA levels of the MRF gene family. Mol. Biol. Rep. 27, 87-98
6. Uozumi, Y., Ito, T., Hoshino, Y., Mohri, T., Maeda, M., Takahashi, K., Fujio, Y., and Azuma, J. (2006) Myogenic differentiation induces taurine transporter in association with taurine-mediated cytoprotection in skeletal muscles. Biochem. J. 394, 699-706
7. Sultan, K.R., Henkel, B., Terlou, M., and Haagsman, H.P. (2006) Quantification of hormone-induced atrophy of large myotubes from C2C12 and L6 cells: atrophy-inducible and atrophy-resistant C2C12 myotubes. Am. J. Physiol. Cell. Physiol. 290, C650-C659
8. Sandri, M., Sandri, C., Gilbert, A., Skurk, C., Calabria, E., Picard, A., Walsh, K., Schiaffino, S., Lecker, S.H., and Goldberg, A.L. (2004) Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell 117, 399-412
9. Stitt, T.N., Drujan, D., Clarke, B.A., Panaro, F., Timofeyva, Y., Kline, W.O., Gonzalez, M., Yancopoulos, G.D., and Glass, D.J. (2004) The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol. Cell. 14, 395-403
10. Tintignac, L.A., Lagirand, J., Batonnet, S., Sirri, V., Leibovitch, M.P., and Leibovitch, S.A. (2005) Degradation of MyoD mediated by the SCF (MAFbx) ubiquitin ligase. J. Biol. Chem. 280, 2847-2856
11. Bodine, S.C., Latres, E., Baumhueter, S., Lai, V.K., Nunez, L., Clarke, B.A., Poueymirou, W.T., Panaro, F.J., Na, E., Dharmarajan, K., Pan, Z.Q., Valenzuela, D.M., DeChiara, T.M., Stitt, T.N., Yancopoulos, G.D., and Glass, D.J. (2001) Identification of ubiquitin ligases required for skeletal muscle atrophy. Science 294, 1704-1708
12. Kamei, Y., Miura, S., Suzuki, M., Kai, Y., Mizukami, J., Taniguchi, T., Mochida, K., Hata, T., Matsuda, J., Aburatani, H., Nishino, I., and Ezaki, O. (2004) Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, down-regulated Type I (slow twitch/red muscle) fiber genes, and impaired glycemic control. J. Biol. Chem. 279, 41114-41123
13. Allen, D.L. and Unterman, T.G. (2007) Regulation of myostatin expression and myoblast differentiation by FoxO and SMAD transcription factors. Am. J. Physiol. Cell Physiol. 292, C188-C199
14. Nishimura, M., Nikawa, T., Kawano, Y., Nakayama, M., and Ikeda, M. (2008) Effects of dimethyl sulfoxide and dexamethasone on mRNA expression of housekeeping genes in cultures of C2C12 myotubes. Biochem. Biophys. Res. Commun. 367, 603-608
15. Nishimura, M., Koeda, A., Suzuki, E., Shimizu, T., Kawano, Y., Nakayama, M., Satoh, T., Narimatsu, S., and Naito, S. (2006) Effects of prototypical drug-metabolizing enzyme inducers on mRNA expression of housekeeping genes in primary cultures of human and rat hepatocytes. Biochem. Biophys. Res. Commun. 346, 1033-1039
16. Nishimura, M., Yamaguchi, M., Yamauchi, A., Ueda, N., and Naito, S. (2005) Role of soybean oil fat emulsion in the prevention of hepatic xenobiotic transporter mRNA up- and down-regulation induced by overdose of fat-free total parenteral nutrition in infant rats. Drug Metab. Pharmacokinet. 20, 46-54
17. Nishimura, M., Koeda, A., Suganuma, Y., Suzuki, E., Shimizu, T., Nakayama, M., Satoh, T., Narimatsu, S., and Naito, S. (2007) Comparison of inducibility of CYP1A and CYP3A mRNAs by prototypical inducers in primary cultures of human, cynomolgus monkey, and rat hepatocytes. Drug Metab. Pharmacokinet. 22, 178-186
18. Foss, D.L., Baarsch, M.J., and Murtaugh, M.P. (1998) Regulation of hypoxanthine phosphoribosyltransferase, glyceraldehyde-3-phosphate dehydrogenase and β-actin mRNA expression in porcine immune cells and tissues. Anim. Biotechnol. 9, 67-78
19. de Kok, J.B., Roelofs, R.W., Giesendorf, B.A., Pennings, J.L., Waas, E.T., Feuth, T., Swinkels, D.W., and Span, P.N. (2005) Normalization of gene expression measurements in tumor tissues: comparison of 13 endogenous control genes. Lab. Invest. 85, 154-159
20. Dehoux, M., Van Beneden, R., Pasko, N., Lause, P., Verniers, J., Underwood, L., Ketelslegers, J.M., and Thissen, J.P. (2004) Role of the insulin-like growth factor I decline in the induction of atrogin-1/MAFbx during fasting and diabetes. Endocrinology 145, 4806-4812
21. Weber, K., Brück, P., Mikes, Z., Küpper, J.H., Klingenspor, M., and Wiesner, R.J. (2002) Glucocorticoid hormone stimulates mitochondrial biogenesis specifically in skeletal muscle. Endocrinology 143, 177-184
22. Hasselgren, P.O. and Fischer, J.E. (2001) Muscle cachexia: current concepts of intracellular mechanisms and molecular regulation. Ann. Surg. 233, 9-17
23. Lynch, G.S., Schertzer, J.D., and Ryall, J.G. (2007) Therapeutic approaches for muscle wasting disorders. Pharmacol. Ther. 113, 461-487
24. Mitch, W.E. and Goldberg, A.L. (1996) Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway. N. Engl. J. Med. 335, 1897-1905
25. Auclair, D., Garrel, D.R., Chaouki Zerouala, A., and Ferland, L.H. (1997) Activation of the ubiquitin pathway in rat skeletal muscle by catabolic doses of glucocorticoids. Am. J. Physiol. 272, C1007-C1016
26. Odedra, B.R., Bates, P.C., and Millward, D.J. (1983) Time course of the effect of catabolic doses of corticosterone on protein turnover in rat skeletal muscle and liver. Biochem. J. 214, 617-627
27. Furuyama, T., Kitayama, K., Yamashita, H., and Mori, N. (2003) Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation. Biochem. J. 375, 365-371
28. Lecker, S.H., Jagoe, R.T., Gilbert, A., Gomes, M., Baracos, V., Bailey, J., Price, S.R., Mitch, W.E., and Goldberg, A.L. (2004) Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. FASEB J. 18, 39-51