MicroRNAs in neurobiology

Brain and Nerve

Volumn 60, Issue 12, 2008, Pages 1437-1444

  Kawahara, Yukio ^a  

^a WISTAR INSTITUTE   (United States)

Author keywords

Gene silencing; MicroRNA; Neurodegeneration; Neurogenesis; RNA editing

Indexed keywords

LET 7 PROTEIN; LIN 28 PROTEIN; MICRORNA; MICRORNA 132; MICRORNA 134; NEUROTRANSMITTER; PROTEIN; UNCLASSIFIED DRUG;

BRAIN DEVELOPMENT; CELL MATURATION; CELL TYPE; CENTRAL NERVOUS SYSTEM; DEGENERATIVE DISEASE; DIAGNOSTIC VALUE; GENE EXPRESSION REGULATION; HUMAN; MITOSIS; NERVE CELL DIFFERENTIATION; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; NEUROBIOLOGY; NEUROTRANSMITTER RELEASE; PROTEIN FAMILY; REVIEW; RNA DEGRADATION; RNA EDITING; RNA INTERFERENCE; SYNAPTOGENESIS; TRANSLATION REGULATION;

ANIMALS; GENE EXPRESSION REGULATION; HUMANS; MICRORNAS; NERVE DEGENERATION; NEUROBIOLOGY; NEUROGENESIS; PROTEIN BIOSYNTHESIS; RNA EDITING; RNA INTERFERENCE; RNA-BINDING PROTEINS;

EID: 57749191956     PISSN: 18816096     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (36)

1. Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, et al: Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433: 769-773, 2005
2. Thomson JM, Newman M, Parker JS, Morin-Kensicki EM, Wright T, et al: Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev 20: 2202-2207, 2006
3. Obernosterer G, Leuschner PJ, Alenius M, Martinez J: Post-transcriptional regulation of microRNA expression. RNA 12: 1161-1167, 2006
4. Wulczyn FG, Smirnova L, Rybak A, Brandt C, Kwidzinski E, et al: Post-transcriptional regulation of the let-7 microRNA during neural cell specification. FASEB J 21: 415-426, 2007
5. Viswanathan SR, Daley GQ, Gregory RI: Selective blockade of microRNA processing by Lin28. Science 320: 97-100, 2008
6. Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, et al: Induced pluripotent stem cell lines derived from human somatic cells. Science 318: 1917-1920, 2007
7. Piskounova E, Viswanathan SR, Janas M, Lapierre RJ, Daley GQ, et al: Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. J Biol Chem 283: 21310-21314, 2008
8. Nishikura K: Editor meets silencer: crosstalk between RNA editing and RNA interference. Nat Rev Mol Cell Biol 7: 919-931, 2006
9. Yang W, Chendrimada TP, Wang Q, Higuchi M, Seeburg PH, et al: Modulation of microRNA processing and expression through RNA editing by ADAR deaminases. Nat Struct Mol Biol 13: 13-21, 2006
10. Kawahara Y, Zinshteyn B, Sethupathy P, Iizasa H, Hatzigeorgiou AG, et al: Redirection of silencing targets by adenosine-to-inosine editing of miRNAs. Science 315: 1137-1140, 2007
11. Kawahara Y, Zinshteyn B, Chendrimada TP, Shiekhattar R, Nishikura K: RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer-TRBP complex. EMBO Rep 8: 763-769, 2007
12. Kawahara Y, Megraw M, Kreider E, Iizasa H, Valente L, et al: Frequency and fate of microRNA editing in human brain. Nucleic Acids Res advanced online publication (doi: 10. 1093/nar/gkn479), 2008
13. Berezikov E, Thuemmler F, van Laake LW, Kondova I, Bontrop R, et al: Diversity of microRNAs in human and chimpanzee brain. Nat Genet 38: 1375-1377, 2006
14. Sempere LF, Freemantle S, Pitha-Rowe I, Moss E, Dmitrovsky E, et al: Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol 5: R13, 2004
15. Lugli G, Torvik VI, Larson J, Smalheiser NR: Expression of microRNAs and their precursors in synaptic fractions of adult mouse forebrain. J Neurochem 106: 650-661, 2008
16. Schaefer A, O'Carroll D, Tan CL, Hillman D, Sugimori M, et al: Cerebellar neurodegeneration in the absence of microRNAs. J Exp Med 204: 1553-1558, 2007
17. Kim J, Inoue K, Ishii J, Vanti WB, Voronov SV, et al: A MicroRNA feedback circuit in midbrain dopamine neurons. Science 317: 1220-1224, 2007
18. Davis TH, Cuellar TL, Koch SM, Barker AJ, Harfe BD, et al: Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus. J Neurosci 28: 4322-4330, 2008
19. Cuellar TL, Davis TH, Nelson PT, Loeb GB, Harfe BD, et al: Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration. Proc Natl Acad Sci U S A 105: 5614-5619, 2008
20. Krichevsky AM, Sonntag KC, Isacson O, Kosik KS: Specific microRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells 24: 857-864, 2006
21. Leucht C, Stigloher C, Wizenmann A, Klafke R, Folchert A, et al: MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary. Nat Neurosci 11: 641-648, 2008
22. Conaco C, Otto S, Han JJ, Mandel G: Reciprocal actions of REST and a microRNA promote neuronal identity. Proc Natl Acad Sci U S A 103: 2422-2427, 2006
23. Visvanathan J, Lee S, Lee B, Lee JW, Lee SK: The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development. Genes Dev 21: 744-749, 2007
24. Makeyev EV, Zhang J, Carrasco MA, Maniatis T: The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol Cell 27: 435-448, 2007
25. Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, et al: Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron 57: 41-55, 2008
26. Schratt GM, Tuebing F, Nigh EA, Kane CG, Sabatini ME, et al: A brain-specific microRNA regulates dendritic spine development. Nature 439: 283-289, 2006
27. Vo N, Klein ME, Varlamova O, Keller DM, Yamamoto T, et al: A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc Natl Acad Sci U S A 102: 16426-16431, 2005
28. Wayman GA, Davare M, Ando H, Fortin D, Varlamova O, et al: An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP. Proc Natl Acad Sci U S A 105: 9093-9098, 2008
29. Klein ME, Lioy DT, Ma L, Impey S, Mandel G, et al: Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA. Nat Neurosci 10: 1513-1514, 2007
30. Srivastava D: Making or breaking the heart: from lineage determination to morphogenesis. Cell 126: 1037-1048, 2006
31. Greco SJ, Rameshwar P: MicroRNAs regulate synthesis of the neurotransmitter substance P in human mesenchymal stem cell-derived neuronal cells. Proc Natl Acad Sci U S A 104: 15484-15489, 2007
32. Stark KL, Xu B, Bagchi A, Lai WS, Liu H, et al: Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nat Genet 40: 751-760, 2008
33. Hebert SS, Horre K, Nicolai L, Papadopoulou AS, Mandemakers W, et al: Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression. Proc Natl Acad Sci U S A 105: 6415-6420, 2008
34. Johnson R, Zuccato C, Belyaev ND, Guest DJ, Cattaneo E, et al: A microRNA-based gene dysregulation pathway in Huntington's disease. Neurobiol Dis 29: 438-445, 2008
35. Karres JS, Hilgers V, Carrera I, Treisman J, Cohen SM: The conserved microRNA miR-8 tunes atrophin levels to prevent neurodegeneration in Drosophila. Cell 131: 136-145, 2007
36. Bilen J, Liu N, Burnett BG, Pittman RN, Bonini NM: MicroRNA pathways modulate polyglutamine-induced neurodegeneration. Mol Cell 24: 157-163, 2006