Protamine sulfate/poly(l-aspartic acid) polyionic complexes self-assembled via electrostatic attractions for combined delivery of drug and gene

Biomaterials

Volumn 30, Issue 6, 2009, Pages 1246-1253

  Cheng, Han ^a   Li, Yong Yong ^a   Zeng, Xuan ^a   Sun, Yun Xia ^a   Zhang, Xian Zheng ^a   Zhuo, Ren Xi ^a  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

Combined delivery; Drug release; Non viral gene vector; Polyionic complex

Indexed keywords

ACIDS; CHROMATOGRAPHY; COLLOIDS; CONFOCAL MICROSCOPY; ELECTROSTATICS; GELATION; NUCLEIC ACIDS; ORGANIC ACIDS; TRANSMISSION ELECTRON MICROSCOPY;

ASPARTIC ACIDS; COMBINED DELIVERY; CONFOCAL LASER SCANNING MICROSCOPIES; DOXORUBICIN; DRUG RELEASE; ELECTROSTATIC ATTRACTIONS; GEL RETARDATIONS; GREEN FLUORESCENT PROTEINS; LUCIFERASE ASSAYS; NON-VIRAL GENE VECTOR; POLYETHYLENIMINE; POLYIONIC COMPLEX; SPHERICAL SHAPES; TRANSFECTION EFFICIENCIES; WEIGHT RATIOS;

VECTORS;

DOXORUBICIN; GREEN FLUORESCENT PROTEIN; POLYETHYLENEIMINE; PROTAMINE SULFATE;

ARTICLE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DRUG DELIVERY SYSTEM; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

CELL DEATH; CELL LINE; CELL SURVIVAL; DNA; DOXORUBICIN; DRUG DELIVERY SYSTEMS; ELECTROPHORESIS, AGAR GEL; GENE TRANSFER TECHNIQUES; GREEN FLUORESCENT PROTEINS; HUMANS; LUCIFERASES; MAGNETIC RESONANCE SPECTROSCOPY; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR WEIGHT; PARTICLE SIZE; PEPTIDES; PROTAMINES; STATIC ELECTRICITY; TRANSFECTION;

EID: 57749191479     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2008.11.002     Document Type: Article

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