Stored Red Blood Cell Transfusion Induces Regulatory T Cells

Journal of the American College of Surgeons

Volumn 208, Issue 1, 2009, Pages 110-119

  Baumgartner, Joel M ^a   Silliman, Christopher C ^b   Moore, Ernest E ^a   Banerjee, Anirban ^a   McCarter, Martin D ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b Bonfils Blood Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD PRESERVATION; ERYTHROCYTE TRANSFUSION; HUMANS; IMMUNE TOLERANCE; IMMUNOCOMPROMISED HOST; LEUKOCYTE REDUCTION PROCEDURES; T-LYMPHOCYTES, REGULATORY; TIME FACTORS;

EID: 57749172255     PISSN: 10727515     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jamcollsurg.2008.08.012     Document Type: Article

References (50)

1. Moore F.A., Moore E.E., and Sauaia A. Blood transfusion. An independent risk factor for postinjury multiple organ failure. Arch Surg 132 (1997) 620-624 discussion 624-625
2. Silliman C.C., and McLaughlin N.J. Transfusion-related acute lung injury. Blood Rev 20 (2006) 139-159
3. Opelz G., Sengar D.P., Mickey M.R., and Terasaki P.I. Effect of blood transfusions on subsequent kidney transplants. Transplant Proc 5 (1973) 253-259
4. Amato A, Pescatori M. Perioperative blood transfusions for the recurrence of colorectal cancer. Cochrane Database Syst Rev 2006;CD005033.
5. Peters W.R., Fry R.D., Fleshman J.W., and Kodner I.J. Multiple blood transfusions reduce the recurrence rate of Crohn's disease. Dis Colon Rectum 32 (1989) 749-753
6. Chang H., Hall G.A., Geerts W.H., et al. Allogeneic red blood cell transfusion is an independent risk factor for the development of postoperative bacterial infection. Vox Sang 78 (2000) 13-18
7. Kristiansson M., Soop M., Shanwell A., and Sundqvist K.G. Prestorage versus bedside white blood cell filtration of red blood cell concentrates: effects on the content of cytokines and soluble tumor necrosis factor receptors. J Trauma 40 (1996) 379-383
8. Mynster T., Dybkjoer E., Kronborg G., and Nielsen H.J. Immunomodulating effect of blood transfusion: is storage time important?. Vox Sang 74 (1998) 176-181
9. Silliman C.C., Voelkel N.F., Allard J.D., et al. Plasma and lipids from stored packed red blood cells cause acute lung injury in an animal model. J Clin Invest 101 (1998) 1458-1467
10. Nielsen H.J., Reimert C.M., Pedersen A.N., et al. Time-dependent, spontaneous release of white cell- and platelet-derived bioactive substances from stored human blood. Transfusion 36 (1996) 960-965
11. Shanwell A., Kristiansson M., Remberger M., and Ringden O. Generation of cytokines in red cell concentrates during storage is prevented by prestorage white cell reduction. Transfusion 37 (1997) 678-684
12. Ghio M., Contini P., Mazzei C., et al. In vitro immunosuppressive activity of soluble HLA class I and Fas ligand molecules: do they play a role in autologous blood transfusion?. Transfusion 41 (2001) 988-996
13. Vamvakas E.C., and Blajchman M.A. Transfusion-related immunomodulation (TRIM): an update. Blood Rev 21 (2007) 327-348
14. Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 6 (2005) 345-352
15. Ziegler S.F. FOXP3: of mice and men. Annu Rev Immunol 24 (2006) 209-226
16. Dieckmann D., Plottner H., Berchtold S., et al. Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood. J Exp Med 193 (2001) 1303-1310
17. Tang Q., and Bluestone J.A. The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. Nat Immunol 9 (2008) 239-244
18. Venet F., Chung C.S., Monneret G., et al. Regulatory T cell populations in sepsis and trauma. J Leukoc Biol 83 (2008) 523-535
19. MacConmara M.P., Maung A.A., Fujimi S., et al. Increased CD4+ CD25+ T regulatory cell activity in trauma patients depresses protective Th1 immunity. Ann Surg 244 (2006) 514-523
20. Kobayashi N., Hiraoka N., Yamagami W., et al. FOXP3+ regulatory T cells affect the development and progression of hepatocarcinogenesis. Clin Cancer Res 13 (2007) 902-911
21. Miracco C., Mourmouras V., Biagioli M., et al. Utility of tumour-infiltrating CD25+FOXP3+ regulatory T cell evaluation in predicting local recurrence in vertical growth phase cutaneous melanoma. Oncol Rep 18 (2007) 1115-1122
22. Griffiths R.W., Elkord E., Gilham D.E., et al. Frequency of regulatory T cells in renal cell carcinoma patients and investigation of correlation with survival. Cancer Immunol Immunother 56 (2007) 1743-1753
23. Curiel T.J., Coukos G., Zou L., et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med 10 (2004) 942-949
24. McCarter M.D., Baumgartner J., Escobar G.A., et al. Immunosuppressive dendritic and regulatory T cells are upregulated in melanoma patients. Ann Surg Oncol 14 (2007) 2854-2860
25. Boschiero L., Nacchia F., Fior F., et al. Specific alloantigen self-control by regulatory T cells in organ transplantation: a review. Transplant Proc 39 (2007) 2013-2017
26. Brecher M.E. Technical manual, AABB. 15th ed. (2005), American Association of Blood Banks, Bethesda, MD
27. Hughes A., Mijovic V., Brozovic B., and Davies T.D. Leucocyte-depleted blood: a comparison of cell-washing techniques. Vox Sang 42 (1982) 145-150
28. Rock G., Baxter A., and Gray E. Leukocyte-depleted blood: a comparison of available preparations. Can Med Assoc J 130 (1984) 1566-1568
29. Uda M., Naito S., Yamamoto K., et al. Optimal protocol for preparation of leukocyte-poor red cells with a blood cell processor. Transfusion 24 (1984) 120-123
30. Gavin M.A., Torgerson T.R., Houston E., et al. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Natl Acad Sci U S A 103 (2006) 6659-6664
31. Roncador G., Brown P.J., Maestre L., et al. Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level. Eur J Immunol 35 (2005) 1681-1691
32. Fritzsching B., Oberle N., Eberhardt N., et al. In contrast to effector T cells, CD4+CD25+FoxP3+ regulatory T cells are highly susceptible to CD95 ligand- but not to TCR-mediated cell death. J Immunol 175 (2005) 32-36
33. Roelen D., Brand A., and Claas F.H. Pretransplant blood transfusions revisited: a role for CD(4+) regulatory T cells?. Transplantation 77 Suppl (2004) S26-S28
34. Claas F.H., Roelen D.L., van Rood J.J., and Brand A. Modulation of the alloimmune response by blood transfusions. Transfus Clin Biol 8 (2001) 315-317
35. Lapierre V., Auperin A., Robinet E., et al. Immune modulation and microchimerism after unmodified versus leukoreduced allogeneic red blood cell transfusion in cancer patients: results of a randomized study. Transfusion 47 (2007) 1691-1699
36. Fu S., Zhang N., Yopp A.C., et al. TGF-beta induces Foxp3+ T-regulatory cells from CD4+ CD25- precursors. Am J Transplant 4 (2004) 1614-1627
37. Koch C.G., Li L., Sessler D.I., et al. Duration of red-cell storage and complications after cardiac surgery. N Engl J Med 358 (2008) 1229-1239
38. Tinmouth A., Fergusson D., Yee I.C., and Hebert P.C. Clinical consequences of red cell storage in the critically ill. Transfusion 46 (2006) 2014-2027
39. Wadhwa M., Seghatchian M.J., Dilger P., et al. Cytokine accumulation in stored red cell concentrates: effect of buffy-coat removal and leucoreduction. Transfus Sci 23 (2000) 7-16
40. Blajchman M.A. The clinical benefits of the leukoreduction of blood products. J Trauma 60 Suppl (2006) S83-S90
41. Bilgin Y.M., van de Watering L.M., Eijsman L., et al. Double-blind, randomized controlled trial on the effect of leukocyte-depleted erythrocyte transfusions in cardiac valve surgery. Circulation 109 (2004) 2755-2760
42. Opelz G., Vanrenterghem Y., Kirste G., et al. Prospective evaluation of pretransplant blood transfusions in cadaver kidney recipients. Transplantation 63 (1997) 964-967
43. Vamvakas E.C. Meta-analysis of randomized controlled trials investigating the risk of postoperative infection in association with white blood cell-containing allogeneic blood transfusion: the effects of the type of transfused red blood cell product and surgical setting. Transfus Med Rev 16 (2002) 304-314
44. Bordin J.O., Bardossy L., and Blajchman M.A. Growth enhancement of established tumors by allogeneic blood transfusion in experimental animals and its amelioration by leukodepletion: the importance of the timing of the leukodepletion. Blood 84 (1994) 344-348
45. MacLennan S., and Williamson L.M. Risks of fresh frozen plasma and platelets. J Trauma 60 Suppl (2006) S46-S50
46. Haas J., Fritzsching B., Trubswetter P., et al. Prevalence of newly generated naive regulatory T cells (Treg) is critical for Treg suppressive function and determines Treg dysfunction in multiple sclerosis. J Immunol 179 (2007) 1322-1330
47. Sarkar S., and Fox D.A. Regulatory T cell defects in rheumatoid arthritis. Arthritis Rheum 56 (2007) 710-713
48. Gambineri E., Torgerson T.R., and Ochs H.D. Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis. Curr Opin Rheumatol 15 (2003) 430-435
49. Perez S.A., Karamouzis M.V., Skarlos D.V., et al. CD4+CD25+ regulatory T-cell frequency in HER-2/neu (HER)-positive and HER-negative advanced-stage breast cancer patients. Clin Cancer Res 13 (2007) 2714-2721
50. Demirkiran A., Kok A., Kwekkeboom J., et al. Low circulating regulatory T-cell levels after acute rejection in liver transplantation. Liver Transpl 12 (2006) 277-284