Microwave-assisted one step synthesis of 8-arylmethyl-9H-purin-6-amines

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 2, 2009, Pages 415-417

  Tao, Hui ^a   Kang, Yanlong ^a   Taldone, Tony ^a   Chiosis, Gabriela ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Cancer; Hsp90; Microwave assisted organic synthesis; Neurodegenerative diseases; Purines

Indexed keywords

HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 INHIBITOR; PURINE DERIVATIVE;

ARTICLE; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; MICROWAVE RADIATION; ONE POT SYNTHESIS;

AMINES; DRUG DISCOVERY; MICROWAVES; PURINES;

EID: 57749120249     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.11.057     Document Type: Article

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15. 3/ammonia MeOH = 25:1) to give the desired product 3.
16. +.
17. +.