3D-QSAR and QSSR studies of 3,8-diazabicyclo[4.2.0]octane derivatives as neuronal nicotinic acetylcholine receptors by comparative molecular field analysis (CoMFA)

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 1, 2009, Pages 127-131

  Ye, Mao ^a   Dawson, Marcia I ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

3D QSAR; 3D QSSR; CoMFA; nAChR; Subtype selectivity

Indexed keywords

3,8 DIAZABICYCLO[4.2.0]OCTANE DERIVATIVE; BICYCLO COMPOUND; NICOTINIC AGENT; OCTANE; UNCLASSIFIED DRUG;

ARTICLE; COMPARATIVE MOLECULAR FIELD ANALYSIS; DRUG DESIGN; DRUG SELECTIVITY; DRUG STRUCTURE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

BICYCLO COMPOUNDS, HETEROCYCLIC; DRUG DESIGN; HUMANS; MODELS, MOLECULAR; NICOTINIC AGONISTS; OCTANES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTORS, NICOTINIC; STATIC ELECTRICITY;

EID: 57749115789     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.11.016     Document Type: Article

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