Effect of food availability and leptin on the physiology and hypothalamic gene expression of the golden spiny mouse: A desert rodent that does not hoard food

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 295, Issue 6, 2008, Pages

  Gutman, Roee ^a   Hacmon Keren, Ronit ^a   Choshniak, Itzhak ^a   Kronfeld Schor, Noga ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Acomys russatus; Desert; Hypothalamic neuropeptides; Thermogenesis; Torpor

Indexed keywords

AGOUTI RELATED PROTEIN; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; LEPTIN; NEUROPEPTIDE Y; PROOPIOMELANOCORTIN;

ACOMYS RUSSATUS; ANIMAL EXPERIMENT; ARTICLE; BODY MASS; CONTROLLED STUDY; CORE TEMPERATURE; DIET RESTRICTION; ENERGY EXPENDITURE; FOOD AVAILABILITY; FOOD INTAKE; GENE EXPRESSION; GOLDEN SPINY MOUSE; HYPOTHALAMUS; MALE; NONHUMAN; PRIORITY JOURNAL; RODENT; THERMOGENESIS;

ADAPTATION, PHYSIOLOGICAL; AGOUTI SIGNALING PROTEIN; ANIMALS; BODY TEMPERATURE REGULATION; BODY WEIGHT; DESERT CLIMATE; EATING; ENERGY METABOLISM; FEEDING BEHAVIOR; FOOD DEPRIVATION; GENE EXPRESSION REGULATION; HYPOTHALAMUS; INFUSIONS, PARENTERAL; LEPTIN; MALE; MURINAE; NERVE TISSUE PROTEINS; NEUROPEPTIDE Y; PRO-OPIOMELANOCORTIN; RNA, MESSENGER; TIME FACTORS;

EID: 57749104916     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00105.2008     Document Type: Article

References (61)

1. Ahima RS, Kelly J, Elmquist JK, Flier SJ. Distinct physiology and neuronal responses to decreased leptin and mild hyperleptinemia. Endocrinology 140: 4923-4937, 1999.
2. Ahima RS, Prabakaran D, Mantzoros C, Qu D, LoIll B, Maratos-Flier E, Flier JS. Role of leptin in the neuroendocrine response to fasting. Nature 382: 250-252, 1996.
3. Bertile F, Oudart H, Criscuolo F, Maho YL, Raclot T. Hypothalamic gene expression in long-term fasted ruts: relationship with body fat. Biochem Biophys Res Commun 303: 1106-1113, 2003.
4. Bi S, Robinson BM, Moran TM. Acute food deprivation and chronic food restriction differentially affect hypothalamic NPY mRNA expression. Am J Physiol Regul Integr Comp Physiol 285: R1030-R1036, 2003.
5. Brito MN, Brito NA, Baro DJ, Song CK, Bartness TJ. Differential activation of the sympathetic innervation of adipose tissue by melanocortin receptor stimulation. Endocrinology 148: 5339-5347, 2007.
6. Collins S, Kuhn CM, Petro AE, Swick AG, Chrunyk BA, Surwit RS. Role of leptin in fat regulation. Nature 380: 677-677, 1996.
7. Danforth E, Burger A. The role of thyroid-hormones in the control of energy-expenditure. Clin Endocrinol Metab 13 : 581-595, 1984.
8. Dark J. Annual lipid cycles in hibernators. Annu Rev Nutri 25: 469-497, 2005.
9. Dark J, Pelz KM. NPY Y1 receptor antagonist prevents NPY-induced torporlike hypothermia in cold-acclimated Siberian hamsters. Am J Physiol Regul Integr Comp Physiol 294: R236-R245, 2008.
10. Dorling H, Schwarzer K, Nuesslein-Hildesheim B, Schmidt I. Leptin selectively increases energy expenditure of food-restricted lean mice. Int J Obes 22: 83-88, 1998.
11. Egawa M, Yoshimatsu H, Bray GA. Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue in rats. Am J Physiol Regul Integr Comp Physiol 260: R328-R334, 1991.
12. Ehrhardt N, Heldmaier G, Exner C. Adaptive mechanisms during food restriction in Acomys russatus: the use of torpor for desert survival. J Comp Physiol B 175: 193-200, 2005.
13. Ellis C, Moar KM, Logie TJ, Ross AW, Morgan PJ, Mercer JG. Diurnal profiles of hypothalamic energy balance gene expression with photoperiod manipulation in the sibirian hamster, Phodopus sungorus. Am J Physiol Regul Integr Comp Physiol 294: R1148-R1153, 2008.
14. Exner C, Hebebrand J, Remschmidt H, Iwetzer C, Ziegler A, Herpertz S, Schweiger U, Blum WF, Preibisch G, Heldmaier G, Klingenspor M. Leptin suppresses semi-starvation induced hyperactivity in rats: implications for anorexia nervosa. Molec Psychol 5: 476-481, 2000.
15. Frederich RC, Löllmann B, Hamann A, Napolitano-Rosen A, Kahn BB, Lowell BB, Flier JS. Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity. J Clin Invest 96: 1658-1663, 1995.
16. Freeman DA, Lewis DA, Kauffman AS, Blum RM, Dark J. Reduced leptin concentrations are permissive for display of torpor in Siberian hamsters. Am J Physiol Regul Integr Comp Physiol 287: R97-R103, 2004.
17. Gantz I, Fong TM. The melanocortin system. Am J Physiol Endocrinol Metab 284: E468-E474, 2003.
18. Gavrilova O, Leon LR, Marcus-Samuels B, Mason MM, Castle AL, Refetoff S, Vinson C, Reitman ML. Torpor in mice is induced by both leptin-dependent and -independent mechanisms. Proc Natl Acad Sci USA 96:14623-14628, 1999.
19. Geiser F, Kortner G, Schmidt I. Leptin increase energy expenditure of a marsupial by inhibition of daily torpor. Am J Physiol Regul Integr Comp Physiol 275: R1627-R1632, 1998.
20. Gelegen C, Collier AD, Campbell CI, Oppelaar H, Kas JHM. Behavioral, physiological and molecular differences in response to dietary restriction in three inbred strains. Am J Physiol Endocrinol Metab 291: E574-E581, 2006.
21. Gutman R, Choshniak I, Kronfeld-Schor N. Defending body mass during food restriction in Acomys russatus: a desert rodent that does not store food. Am J Physiol Regul Integr Comp Physiol 290: R881-R891, 2006.
22. Gutman R, Yosha D, Choshniak I, Kronfeld-Schor N. Two strategies for coping with food shortage in desert golden spiny mice. Physiol Behav 90: 95-102, 2007.
23. Halaas JL, Boozer C, Blair-West J, Fidahusein N, Denton DA, Friedman JM. Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. Proc Natl Acad Sci USA 94: 8878-8883, 1997.
24. 23a.Heldmaier G and Ruf T. Body-temperature and metabolic-rate during natural hypothermia in endotherms. J Comp Physiol [B] 162: 696-706, 1992.
25. Hillebrand JJG, Kas MJH, Adan RAH. α-MSH enhances activity-based anorexia. Peptides 26: 1690-1696, 2005.
26. Hillebrand JJG, Kas MJH, Scheurink AJW, Dijk GV, Adan RAH. AgRP(83-132) and SHU9119 differently affects activity-based anorexia. Eur Neuropsychopharmacol 16: 403-412, 2006.
27. Ioffe E, Moon B, Connolly E, Friedman JM. Abnormal regulation of the leptin gene in the pathogenesis of obesity. Proc Natl Acad Sci USA 95: 11852-11857, 1998.
28. Jacobson L. Middle-aged C57BL/6 mice have impaired response to leptin that are not improved by caloric restriction. Am J Physiol Endocrinol Metab 282: E786-E793, 2002.
29. Jaffe S. Climate of Israel. In: The Zoogeography of Israel, edited by Yom-Tov Y and Tchernov E. Dordrecht: Dr. W. Junk Publishers, 1988, p. 79-94.
30. Kinlaw A. A review of borrowing by semi-fossorial vertebrates in arid environments. J Arid Environ 41: 127-145, 1999.
31. Kleiber M. The Fire of Life. New York: John Wiley and Sons, 1961.
32. Kronfeld N, Dayan T. The dietary basis for temporal partitioning: Food habits of coexisting Acomys species. Oecologia (Berl) 121: 123-128, 1999.
33. Kronfeld-Schor N, Silvia Kunz AB, TH, Richardson C, Widmaier EP. Dissociation of leptin secretion and adiposity during pre-hibernation fattening in little brown bats. Am J Physiol Regul Integr Comp Physiol 279: R1277-R1281, 2000.
34. Kronfeld-Schor N, Silvia AB, Bicer E, Mathews PT, Kunz TH, Widmaier EP. Steroid-dependent up-regulation of adipose leptin secretion in vitro during pregnancy in mice. Biol Reprod 63: 274-280. 2000.
35. Kronfeld-Schor N, Zhao J, Silvia BA, Mathews PT, Zimmerman S, Widmaier EP, Kunz. TH. Hyperleptinemia in pregnant bats is characterized by increased placental leptin secretion in vitro. Endocrine 14: 225-233, 2001.
36. Kunz TH, Wrazen JA, Burnett CD. Changes in body mass and fat reserves in pre-hibernating little brown bats (Myotis lucifugus). Ecoscience 5: 8-17, 1998.
37. Lindstedt SL, Boyce MS. Seasonality, fasting endurance, and body size in mammals. Am Nat 125: 873-878, 1985.
38. Louw G, Seely M. Ecology of Desert Organisms. London: Longram, 1982.
39. Mendelssohn H, Yom-Tov Y. Fauna Palestina: Mammalia of Israel. Jerusalem: Israel: Israel Academy of Sciences and Humanities, 1999.
40. Mercer G, Moar KM, Logie TJ, Findlay PA, Adam CL, Morgan PJ. Seasonally inappropriate body weight induced by food restriction: effect on hypothalamic gene expression in male Siberian hamsters. Endocrinology 142: 4173-4181.
41. Merkt J, Taylor CR. A metabolic switch for surviving famines in the desert. Proc Natl Acad Sci USA 91: 12313-12316, 1994.
42. Mistry AM, Swick AG, Romsos DR. Leptin rapidly lowers food intake and elevates metabolic rates in lean and ob/ob mice. J Nutr 127: 2065-2072, 1997.
43. Nicol S, Pavlides D, Andersen NA. Nonshivering thermogenesis in marsupials: Absence of thermogenic response to β3-adrenergic agonists. Comp Biochem Physiol A 117: 399-403, 1997.
44. Mrosovsky N. Lipid programmers and life strategies in hibernators. Am Zool 16: 685-697, 1976.
45. Overton JM, Williams TD, Chambers JB, Rashotte ME. Central leptin infusion attenuates the cardiovascular and metabolic effects of fasting in rats. Hypertension 37: 663-669, 2001.
46. Paul MJ, Freeman DA, Park JH, Dark J. Neuropeptide Y induces torpor-like hypothermia in Siberian hamsters. Brain Res 1055: 83-92, 2005.
47. Pelz KM, Dark J. ICV NPY Y1 receptor agonist but not Y5 agonist induces torpor-like hypothermia in cold-acclimated Siberian hamsters. Am J Physiol Regul Integr Comp Physiol 292: R2299-R2311, 2007.
48. Pierce BJ, McWilliams SR. Seasonal changes in composition of lipid stores in migratory birds: causes and consequences. The Condor 107: 269-279, 2005.
49. Scarpace PJ, Matheny M, Pollock BH, Tumer N. Leptin increases uncoupling protein expression and energy expenditure. Am J Physiol Endocrinol Metab 273: E226-E230, 1997.
50. Schneider JE, Blum RM, Wade GN. Metabolic control of food intake and estrous sycle in Syrian hamsters. I. Plasma insulin and leptin. Am J Physiol Regul Integr Comp Physiol 278: R476-R485, 2000.
51. Schwartz MW, Woods SC, Seeley RJ, Barsh GS, Baskin DG, Leibel RL. Is the energy homeostasis system inherently biased toward weight gain? Diabetes 52: 232-238, 2003.
52. Shargal E, Kronfeld-Schor N, Dayan T. Population biology and spatial relationships of coexisting spiny mice (Acomys) in Israel. J Mammal 81: 1046-1052, 2000.
53. Shkolnik A. Studies in the Comparative Biology of Israel's Two Species of Spiny Mice (Genus Acomys) [in Hebrew, English summary] (PhD thesis). Jerusalem, Israel: Hebrew University, 1966.
54. Shkolnik A, Borut A. Temperature and water relations in two species of spiny mice (Acomys). J Mammal 50: 245-255, 1969.
55. Stehling O, Doring H, Ertl J, Preibisch G, Schmidt I. Leptin reduces juvenile fat stores by altering the circadian cycle of energy expenditure. Am J Physiol Regul Integr Comp Physiol 271: R1770-R1774, 1996.
56. Surmely JF, Voirol MJ, Stefanoni N, Assimacopoulos-Jeannet F, Giacobino JP, Jequier E, Gaillard RC and Tappy L. Stimulation by leptin of H-3 GDP binding to brown adipose tissue of fasted but not fed rats. Int J Obes 22: 923-926, 1998.
57. Swoap SJ, Gutilla MJ, Liles LC, Smith RO, Weinshenker D. The full expression of fasting-induced torpor requires β3-adrenergic receptor signaling. J Neurosci 26: 241-245, 2006.
58. Swart I, Jang JW, Overton JM, Houpt TA. Hypothalamic NPY, AGRP and POMC mRNA responses to leptin and refeeding in mice. Am J Physiol Regul Integr Comp Physiol 283: R1020-R1026, 2002.
59. Takahashi N, Patel HR, Qi Y, Dushay J, Ahima RS. Divergent effects of leptin in mice susceptible or resistant to obesity. Horm Metab Res 34: 691-697, 2002.
60. Wade NG. Regulation of body fat content? Am J Physiol Regul Integr Comp Physiol 286: R14-R15, 2004.
61. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 372: 425-432, 1994.