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Volumn 26, Issue 1, 2005, Pages 229-238

Colonic adenocarcinomas rapidly induced by the combined treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate in male ICR mice possess β-catenin gene mutations and increases immunoreactivity for β-catenin, cyclooxygenase-2 and inducible nitric oxide synthase

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; 2 AMINO 3,8 DIMETHYLIMIDAZO[4,5 F]QUINOXALINE; BETA CATENIN; CYCLOOXYGENASE 2; DRINKING WATER; INDUCIBLE NITRIC OXIDE SYNTHASE; SODIUM SULFATE;

EID: 13444261395     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgh292     Document Type: Article
Times cited : (87)

References (53)
  • 1
    • 0034056019 scopus 로고    scopus 로고
    • Nutrition and dietary carcinogens
    • Sugimura,T. (2000) Nutrition and dietary carcinogens. Carcinogenesis, 21, 387-395.
    • (2000) Carcinogenesis , vol.21 , pp. 387-395
    • Sugimura, T.1
  • 2
    • 0142102341 scopus 로고    scopus 로고
    • Changes in colorectal cancer during a 20-year period: An extended report from the multi-institutional registry of large bowel cancer, Japan
    • Kotake,K., Honjo,S., Sugihara,K., Kato,T., Kodaira,S., Takahashi,T., Yasutomi,M., Muto,T. and Koyama,Y. (2003) Changes in colorectal cancer during a 20-year period: an extended report from the multi-institutional registry of large bowel cancer, Japan. Dis. Colon Rectum, 46 (10 suppl.), 532-543.
    • (2003) Dis. Colon Rectum , vol.46 , Issue.10 SUPPL. , pp. 532-543
    • Kotake, K.1    Honjo, S.2    Sugihara, K.3    Kato, T.4    Kodaira, S.5    Takahashi, T.6    Yasutomi, M.7    Muto, T.8    Koyama, Y.9
  • 4
    • 0033393815 scopus 로고    scopus 로고
    • A new approach to risk estimation of food-borne carcinogens-heterocyclic amines-based on molecular information
    • Nagao,M. (1999) A new approach to risk estimation of food-borne carcinogens-heterocyclic amines-based on molecular information. Mutat. Res., 431, 3-12.
    • (1999) Mutat. Res. , vol.431 , pp. 3-12
    • Nagao, M.1
  • 5
    • 0030981184 scopus 로고    scopus 로고
    • Overview of carcinogenic heterocyclic amines
    • Sugimura,T. (1997) Overview of carcinogenic heterocyclic amines. Mutat. Res., 376, 211-219.
    • (1997) Mutat. Res. , vol.376 , pp. 211-219
    • Sugimura, T.1
  • 6
    • 0002478344 scopus 로고    scopus 로고
    • 7.1 Rodents
    • Nagao,M. and Sugimura,T. (eds), John Wiley & Sons, Ltd, New York, NY
    • Ohgaki H. (2000) 7.1 Rodents. In Nagao,M. and Sugimura,T. (eds), Food Borne Carcinogens: Heterocyclic Amines. John Wiley & Sons, Ltd, New York, NY, pp. 198-228.
    • (2000) Food Borne Carcinogens: Heterocyclic Amines , pp. 198-228
    • Ohgaki, H.1
  • 7
    • 0037201650 scopus 로고    scopus 로고
    • Comments on the history and importance of aromatic and heterocyclic amines in public health
    • Weisburger,J.H. (2002) Comments on the history and importance of aromatic and heterocyclic amines in public health. Mutat. Res., 506/507, 9-20.
    • (2002) Mutat. Res. , vol.506-507 , pp. 9-20
    • Weisburger, J.H.1
  • 10
    • 0031008972 scopus 로고    scopus 로고
    • Exposure assessment of heterocyclic amines (HCAs) in epidemiologic studies
    • Sinha,R. and Rothman,N. (1997) Exposure assessment of heterocyclic amines (HCAs) in epidemiologic studies. Mutat. Res., 376, 195-202.
    • (1997) Mutat. Res. , vol.376 , pp. 195-202
    • Sinha, R.1    Rothman, N.2
  • 11
    • 34547440966 scopus 로고    scopus 로고
    • IARC Scientific Publications, IARC, Lyon
    • Sinha,R. and Norat,T. (2002) Meat Cooking and Cancer Risk, Volume 156. IARC Scientific Publications, IARC, Lyon, pp. 181-186.
    • (2002) Meat Cooking and Cancer Risk , vol.156 , pp. 181-186
    • Sinha, R.1    Norat, T.2
  • 13
    • 0023629080 scopus 로고
    • Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: Preliminary findings
    • Bird,R.P. (1987) Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings. Cancer Lett., 37, 147-151.
    • (1987) Cancer Lett. , vol.37 , pp. 147-151
    • Bird, R.P.1
  • 14
    • 0029842309 scopus 로고    scopus 로고
    • Efficient method for rapid induction of aberrant crypt foci in rats with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
    • Ochiai,M., Nakagama,H., Watanabe,M., Ishiguro,Y., Sugimura.T. and Nagao,M. (1996) Efficient method for rapid induction of aberrant crypt foci in rats with 2-amino-1-methyl-6-phenylimidazo[4,5-b pyridine. Jpn. J. Cancer Res., 87, 1029-1033.
    • (1996) Jpn. J. Cancer Res. , vol.87 , pp. 1029-1033
    • Ochiai, M.1    Nakagama, H.2    Watanabe, M.3    Ishiguro, Y.4    Sugimura, T.5    Nagao, M.6
  • 15
    • 0030596190 scopus 로고    scopus 로고
    • The role of aberrant crypt foci induced by the two heterocyclic amines 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ) and 2-amino-1-methyl-6-phenyl-imidazo[4,5-b]pyridine (PhIP) in the development of colon cancer in mice
    • Kristiansen,E. (1996) The role of aberrant crypt foci induced by the two heterocyclic amines 2-amino-3-methyl-imidazo[4,5-f quinoline (IQ) and 2-amino-1-methyl-6-phenyl-imidazo[4,5-b pyridine (PhIP) in the development of colon cancer in mice. Cancer Lett., 110, 187-192.
    • (1996) Cancer Lett. , vol.110 , pp. 187-192
    • Kristiansen, E.1
  • 16
    • 0025768966 scopus 로고
    • A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)
    • Ito,N., Hasegawa,R., Sano,M., Tamano,S., Esumi,H., Takayama,S. and Sugimura,T. (1991) A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Carcinogenesis, 12, 1503-1506.
    • (1991) Carcinogenesis , vol.12 , pp. 1503-1506
    • Ito, N.1    Hasegawa, R.2    Sano, M.3    Tamano, S.4    Esumi, H.5    Takayama, S.6    Sugimura, T.7
  • 17
    • 0036313879 scopus 로고    scopus 로고
    • Induction of intestinal tumors and lymphomas in C57BL/6N mice by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine
    • Ochiai,M., Imai,H., Sugimura,T., Nagao,M. and Nakagama,H. (2002) Induction of intestinal tumors and lymphomas in C57BL/6N mice by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine. Jpn. J. Cancer Res., 63, 478-483.
    • (2002) Jpn. J. Cancer Res. , vol.63 , pp. 478-483
    • Ochiai, M.1    Imai, H.2    Sugimura, T.3    Nagao, M.4    Nakagama, H.5
  • 18
    • 0032785057 scopus 로고    scopus 로고
    • Difference in target organs in carcinogenicity of a heterocyclic amine, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline, in different strains of mice
    • Fujita,H., Nagano,K., Ochiai,M., Ushijima,T., Sugimura,T., Nagao,M. and Mastushima,T. (1999) Difference in target organs in carcinogenicity of a heterocyclic amine, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline, in different strains of mice. Jpn. J. Cancer Res., 90, 1203-1206.
    • (1999) Jpn. J. Cancer Res. , vol.90 , pp. 1203-1206
    • Fujita, H.1    Nagano, K.2    Ochiai, M.3    Ushijima, T.4    Sugimura, T.5    Nagao, M.6    Mastushima, T.7
  • 19
    • 0035976041 scopus 로고    scopus 로고
    • Essential similarities between spontaneous and MeIQx-promoted aberrant crypt foci in the F344 rat colon
    • Tanakamaru,Z., Mori,I., Nishikawa,A., Furukawa,F., Takahashi,M. and Mori,H. (2001) Essential similarities between spontaneous and MeIQx-promoted aberrant crypt foci in the F344 rat colon. Cancer Lett., 172, 143-149.
    • (2001) Cancer Lett. , vol.172 , pp. 143-149
    • Tanakamaru, Z.1    Mori, I.2    Nishikawa, A.3    Furukawa, F.4    Takahashi, M.5    Mori, H.6
  • 20
    • 0031014337 scopus 로고    scopus 로고
    • Induction of aberrant crypt foci in C57BL/6N mice by 2-amino-9H-pyrido[2,3-b]indole (AαC) and 2-amino-3,8-dimethylimidazo[4,5-f] quinoxaline (MeIQx)
    • Okonogi,H., Ushijima,T., Shimizu,H., Sugimura,T. and Nagao,M. (1997) Induction of aberrant crypt foci in C57BL/6N mice by 2-amino-9H-pyrido[2,3-b]indole (AαC) and 2-amino-3,8-dimethylimidazo[4,5-f] quinoxaline (MeIQx). Cancer Lett., 111, 105-109.
    • (1997) Cancer Lett. , vol.111 , pp. 105-109
    • Okonogi, H.1    Ushijima, T.2    Shimizu, H.3    Sugimura, T.4    Nagao, M.5
  • 21
    • 0029964851 scopus 로고    scopus 로고
    • Signal transduction through β-catenin and specification of cell fate during embryogenesis
    • Miller,J.R. and Moon,R.T. (1996) Signal transduction through β-catenin and specification of cell fate during embryogenesis. Genes Dev., 10, 2527-2539.
    • (1996) Genes Dev. , vol.10 , pp. 2527-2539
    • Miller, J.R.1    Moon, R.T.2
  • 22
    • 0032079884 scopus 로고    scopus 로고
    • Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of β-catenin
    • Kishida,S., Yamamoto,H., Ikeda,S., Kishida,M., Sakamoto,I., Koyama,S. and Kikuchi,A. (1998) Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of β-catenin. J. Biol. Chem., 273 10823-10826.
    • (1998) J. Biol. Chem. , vol.273 , pp. 10823-10826
    • Kishida, S.1    Yamamoto, H.2    Ikeda, S.3    Kishida, M.4    Sakamoto, I.5    Koyama, S.6    Kikuchi, A.7
  • 23
    • 0032521538 scopus 로고    scopus 로고
    • High frequency of β-catenin (ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rat
    • Dashwood,R.H., Suzui,M., Nakagama,H., Sugimura,T. and Nagao,M. (1998) High frequency of β-catenin (ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rat. Cancer Res., 58, 1127-1129.
    • (1998) Cancer Res. , vol.58 , pp. 1127-1129
    • Dashwood, R.H.1    Suzui, M.2    Nakagama, H.3    Sugimura, T.4    Nagao, M.5
  • 24
    • 0032958592 scopus 로고    scopus 로고
    • Frequent mutations of the rat β-catenin gene in colon cancers induced by methylazoxymethanol acetate plus 1-hydroxyanthraquinone
    • Suzui,M., Ushijima,T., Dashwood,R.H., Yoshimi,N., Sugimura,T., Mori,H. and Nagao,M. (1999) Frequent mutations of the rat β-catenin gene in colon cancers induced by methylazoxymethanol acetate plus 1-hydroxyanthraquinone. Mol Carcinogen., 24, 232-237.
    • (1999) Mol. Carcinogen. , vol.24 , pp. 232-237
    • Suzui, M.1    Ushijima, T.2    Dashwood, R.H.3    Yoshimi, N.4    Sugimura, T.5    Mori, H.6    Nagao, M.7
  • 25
    • 0031984227 scopus 로고    scopus 로고
    • β-Catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors
    • Takahashi,M., Fukuda,K., Sugimura,T. and Wakabayashi,K. (1998) β-Catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors. Cancer Res., 58, 42-46.
    • (1998) Cancer Res. , vol.58 , pp. 42-46
    • Takahashi, M.1    Fukuda, K.2    Sugimura, T.3    Wakabayashi, K.4
  • 26
    • 0034122380 scopus 로고    scopus 로고
    • Frequent mutations of the β-catenin gene in mouse colon tumors induced by azoxymethane
    • Takahashi,M., Nakatsugi,S., Sugimura,T. and Wakabayashi,K. (2000) Frequent mutations of the β-catenin gene in mouse colon tumors induced by azoxymethane. Carcinogenesis, 21, 1117-1120.
    • (2000) Carcinogenesis , vol.21 , pp. 1117-1120
    • Takahashi, M.1    Nakatsugi, S.2    Sugimura, T.3    Wakabayashi, K.4
  • 30
    • 0032521433 scopus 로고    scopus 로고
    • Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer
    • Sparks,A.B., Morin,P.J., Vogelstein,B. and Kinzler,K.W. (1998) Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer. Cancer Res., 58, 1130-1134.
    • (1998) Cancer Res. , vol.58 , pp. 1130-1134
    • Sparks, A.B.1    Morin, P.J.2    Vogelstein, B.3    Kinzler, K.W.4
  • 31
    • 0033738261 scopus 로고    scopus 로고
    • Expression of β-catenin and full-length APC protein in normal and neoplastic colonic tissues
    • Iwamoto,M., Ahnen,D.J., Franklin,W.A. and Maltzman,T.H. (2000) Expression of β-catenin and full-length APC protein in normal and neoplastic colonic tissues. Carcinogenesis, 21, 1935-1940.
    • (2000) Carcinogenesis , vol.21 , pp. 1935-1940
    • Iwamoto, M.1    Ahnen, D.J.2    Franklin, W.A.3    Maltzman, T.H.4
  • 32
    • 0344237231 scopus 로고    scopus 로고
    • A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate
    • Tanaka,T., Kohno,H., Suzuki,R., Yamada,Y., Sugie,S. and Mori,H. (2003) A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate. Cancer Sci. 94, 965-973.
    • (2003) Cancer Sci. , vol.94 , pp. 965-973
    • Tanaka, T.1    Kohno, H.2    Suzuki, R.3    Yamada, Y.4    Sugie, S.5    Mori, H.6
  • 33
    • 0016374178 scopus 로고
    • Morphogenesis of chemically induced neoplasms of the colon and small intestine in rats
    • Ward,J.M. (1974) Morphogenesis of chemically induced neoplasms of the colon and small intestine in rats. Lab. Invest., 30, 505-513.
    • (1974) Lab. Invest. , vol.30 , pp. 505-513
    • Ward, J.M.1
  • 34
    • 0037201538 scopus 로고    scopus 로고
    • A rat colon cancer model induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, PhIP
    • Nakagama,H., Ochiai,M., Ubagai,T., Tajima,R., Fujiwara,K., Sugimura,T. and Nagao,M. (2002) A rat colon cancer model induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, PhIP. Mutat. Res., 506-507, 137-144.
    • (2002) Mutat. Res. , vol.506-507 , pp. 137-144
    • Nakagama, H.1    Ochiai, M.2    Ubagai, T.3    Tajima, R.4    Fujiwara, K.5    Sugimura, T.6    Nagao, M.7
  • 35
    • 0033860988 scopus 로고    scopus 로고
    • More frequent β-catenin gene mutations in adenomas than in aberrant crypt foci or adenocarcinomas in the large intestines of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-treated rats
    • Tsukamoto,T., Tanaka,H., Fukami,H., Inoue,M., Takahashi,M., Wakabayashi,K. and Tatematsu,M. (2000) More frequent β-catenin gene mutations in adenomas than in aberrant crypt foci or adenocarcinomas in the large intestines of 2-amino-1-methyl-6-phenylimidazo[4,5-b pyridine (PhIP)-treated rats. Jpn. J. Cancer Res., 91, 792-796.
    • (2000) Jpn. J. Cancer Res. , vol.91 , pp. 792-796
    • Tsukamoto, T.1    Tanaka, H.2    Fukami, H.3    Inoue, M.4    Takahashi, M.5    Wakabayashi, K.6    Tatematsu, M.7
  • 36
    • 0036200869 scopus 로고    scopus 로고
    • Efficient induction of rat large intestinal tumors with a new spectrum of mutations by intermittent administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in combination with a high fat diet
    • Ubagai,T., Ochiai,M., Kawamori,T., Imai,H., Sugimura,T., Nagao,M. and Nakagama,H. (2002) Efficient induction of rat large intestinal tumors with a new spectrum of mutations by intermittent administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in combination with a high fat diet. Carcinogenesis, 23, 197-200.
    • (2002) Carcinogenesis , vol.23 , pp. 197-200
    • Ubagai, T.1    Ochiai, M.2    Kawamori, T.3    Imai, H.4    Sugimura, T.5    Nagao, M.6    Nakagama, H.7
  • 37
    • 0141760328 scopus 로고    scopus 로고
    • Characterization of dysplastic aberrant crypt foci in the rat colon induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
    • Ochiai,M., Ushigome,M., Fujiwara,K., Ubagai,T., Kawamori,T., Sugimura,T., Nagao,M. and Nakagama,H. (2003) Characterization of dysplastic aberrant crypt foci in the rat colon induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Am. J. Pathol. 163, 1607-1614.
    • (2003) Am. J. Pathol. , vol.163 , pp. 1607-1614
    • Ochiai, M.1    Ushigome, M.2    Fujiwara, K.3    Ubagai, T.4    Kawamori, T.5    Sugimura, T.6    Nagao, M.7    Nakagama, H.8
  • 38
    • 0032810316 scopus 로고    scopus 로고
    • Genetic analysis of the susceptibility in rats to aberrant crypt foci formation by 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine, PhIP
    • Nakagama,H., Souda,K., Ochiai,M., Ishiguro,Y., Sugimura,T. and Nagao,M. (1999) Genetic analysis of the susceptibility in rats to aberrant crypt foci formation by 2-amino-1-methyl-6-phenylimidazo [4,5- b]pyridine, PhIP. Cancer Lett., 143, 205-209.
    • (1999) Cancer Lett. , vol.143 , pp. 205-209
    • Nakagama, H.1    Souda, K.2    Ochiai, M.3    Ishiguro, Y.4    Sugimura, T.5    Nagao, M.6
  • 39
    • 0026469750 scopus 로고
    • Adduct formation at C-8 of guanine on in vitro reaction of the ultimate form of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine with 2′-deoxyguanosine and its phosphate esters
    • Nagaoka,H., Wakabayashi,K., Kim,S.B., Kim,I.S., Tanaka,Y., Ochiai,M., Tada,A., Nukaya,H., Sugimura,T. and Nagao,M. (1992) Adduct formation at C-8 of guanine on in vitro reaction of the ultimate form of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine with 2′-deoxyguanosine and its phosphate esters. Jpn. J. Cancer Res., 83, 1025-1029.
    • (1992) Jpn. J. Cancer Res. , vol.83 , pp. 1025-1029
    • Nagaoka, H.1    Wakabayashi, K.2    Kim, S.B.3    Kim, I.S.4    Tanaka, Y.5    Ochiai, M.6    Tada, A.7    Nukaya, H.8    Sugimura, T.9    Nagao, M.10
  • 40
    • 0035168392 scopus 로고    scopus 로고
    • Predominant mutation of codon 41 of the β-catenin proto-oncogene in rat colon tumors induced by 1,2-dimethylhydrazine using a complete carcinogenic protocol
    • Koesters,R., Hans,M., Benner,A., Prosst,R., Boehm,J., Gahlen,J. and Doeberitz,M.K. (2001) Predominant mutation of codon 41 of the β-catenin proto-oncogene in rat colon tumors induced by 1,2-dimethylhydrazine using a complete carcinogenic protocol. Carcinogenesis, 22, 1885-1890.
    • (2001) Carcinogenesis , vol.22 , pp. 1885-1890
    • Koesters, R.1    Hans, M.2    Benner, A.3    Prosst, R.4    Boehm, J.5    Gahlen, J.6    Doeberitz, M.K.7
  • 41
    • 0033924401 scopus 로고    scopus 로고
    • Altered expression of β-catenin, inducible nitric oxide synthase and cyclooxygenase-2 in azoxymethane-induced rat colon carcinogenesis
    • Takabashi,M., Mutoh,M., Kawamori,T., Sugimura,T. and Wakabayashi,K. (2000) Altered expression of β-catenin, inducible nitric oxide synthase and cyclooxygenase-2 in azoxymethane-induced rat colon carcinogenesis. Carcinogenesis, 21, 1319-1327.
    • (2000) Carcinogenesis , vol.21 , pp. 1319-1327
    • Takabashi, M.1    Mutoh, M.2    Kawamori, T.3    Sugimura, T.4    Wakabayashi, K.5
  • 42
    • 0030606276 scopus 로고    scopus 로고
    • Self-promotion? Intimate connections between APC and prostaglandin H synthase-2
    • Prescott,S.M. and White,R.L. (1996) Self-promotion? Intimate connections between APC and prostaglandin H synthase-2. Cell, 87 783-786.
    • (1996) Cell , vol.87 , pp. 783-786
    • Prescott, S.M.1    White, R.L.2
  • 43
    • 0033119190 scopus 로고    scopus 로고
    • Transcriptional activation of cyclooxygenase-2 in Wnt-1-transformed mouse mammary epithelial cells
    • Howe,L.R., Subbaramaiah,K., Chung,W.J., Dannenberg,A.J. and Brown,A.M. (1999) Transcriptional activation of cyclooxygenase-2 in Wnt-1-transformed mouse mammary epithelial cells. Cancer Res., 59, 1572-1577.
    • (1999) Cancer Res. , vol.59 , pp. 1572-1577
    • Howe, L.R.1    Subbaramaiah, K.2    Chung, W.J.3    Dannenberg, A.J.4    Brown, A.M.5
  • 44
    • 0032991775 scopus 로고    scopus 로고
    • Differential expression of prostaglandin endoperoxide H synthase-2 and formation of activated β-catenin-LEF-1 transcription complex in mouse colonic epithelial cells contrasting in Apc
    • Mei,J.M., Hord,N.G., Winterstein,D.F., Donald,S.P. and Phang,J.M. (1999) Differential expression of prostaglandin endoperoxide H synthase-2 and formation of activated β-catenin-LEF-1 transcription complex in mouse colonic epithelial cells contrasting in Apc. Carcinogenesis, 20, 737-740.
    • (1999) Carcinogenesis , vol.20 , pp. 737-740
    • Mei, J.M.1    Hord, N.G.2    Winterstein, D.F.3    Donald, S.P.4    Phang, J.M.5
  • 45
    • 0033119801 scopus 로고    scopus 로고
    • β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu,O. and McCormick,F. (1999) β-Catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature, 398 422-426.
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 48
    • 0036144387 scopus 로고    scopus 로고
    • Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with celecoxib, a selective cyclooxygenase-2 inhibitor
    • Rao,C.V., Indranie,C., Simi,B., Manning,P.T., Connor,J.R. and Reddy,B.S. (2002) Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with celecoxib, a selective cyclooxygenase-2 inhibitor. Cancer Res., 62, 165-170.
    • (2002) Cancer Res. , vol.62 , pp. 165-170
    • Rao, C.V.1    Indranie, C.2    Simi, B.3    Manning, P.T.4    Connor, J.R.5    Reddy, B.S.6
  • 49
    • 0035296203 scopus 로고    scopus 로고
    • Role of nitric oxide in carcinogenesis and tumour progression
    • Lala,P.K. and Chakraborty,C. (2001) Role of nitric oxide in carcinogenesis and tumour progression. Lancet Oncol., 2, 149-156.
    • (2001) Lancet Oncol. , vol.2 , pp. 149-156
    • Lala, P.K.1    Chakraborty, C.2
  • 50
    • 0036313896 scopus 로고    scopus 로고
    • Inhibition of chronic ulcerative colitis-associated colorectal adenocarcinoma development in a murine model by N-acetylcysteine
    • Seril,D.N., Liao,J., Ho,K.L., Yang,C.S. and Yang,G.Y. (2002) Inhibition of chronic ulcerative colitis-associated colorectal adenocarcinoma development in a murine model by N-acetylcysteine. Carcinogenesis, 23, 993-1001.
    • (2002) Carcinogenesis , vol.23 , pp. 993-1001
    • Seril, D.N.1    Liao, J.2    Ho, K.L.3    Yang, C.S.4    Yang, G.Y.5
  • 51
    • 0036821907 scopus 로고    scopus 로고
    • Part II: Beneficial effects of the peroxynitrite decomposition catalyst FP15 in murine models of arthritis and
    • Mabley,J.G., Liaudet,L., Pacher,P., Southan,G.J., Salzman,A.L. and Szabo,C. (2002) Part II: beneficial effects of the peroxynitrite decomposition catalyst FP15 in murine models of arthritis and colitis. Mol. Med., 8, 581-590.
    • (2002) Colitis Mol. Med. , vol.8 , pp. 581-590
    • Mabley, J.G.1    Liaudet, L.2    Pacher, P.3    Southan, G.J.4    Salzman, A.L.5    Szabo, C.6
  • 52
    • 5044228671 scopus 로고    scopus 로고
    • Sequential observations on the occurrence of preneoplastic and neoplastic lesions in the mouse colon treated with azoxymethane and dextran sodium sulfate
    • Suzuki,R., Kohno,H., Sugie,S. and Tanaka,T. (2004) Sequential observations on the occurrence of preneoplastic and neoplastic lesions in the mouse colon treated with azoxymethane and dextran sodium sulfate. Cancer Sci., 95, 721-727.
    • (2004) Cancer Sci. , vol.95 , pp. 721-727
    • Suzuki, R.1    Kohno, H.2    Sugie, S.3    Tanaka, T.4
  • 53
    • 0028218474 scopus 로고
    • Chronic infections and inflammatory processes as cancer risk factors: Possible role of nitric oxide in carcinogenesis
    • Ohshima, H. and Bartsch,H. (1994) Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis. Mutat Res., 305, 253-264.
    • (1994) Mutat. Res. , vol.305 , pp. 253-264
    • Ohshima, H.1    Bartsch, H.2


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