메뉴 건너뛰기




Volumn 17, Issue 4, 2007, Pages 173-177

Tinkering with heparan sulfate sulfation to steer development

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN SULF; PROTEOHEPARAN SULFATE; SULFATASE; UNCLASSIFIED DRUG;

EID: 33947714581     PISSN: 09628924     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tcb.2007.02.006     Document Type: Review
Times cited : (68)

References (52)
  • 2
    • 0035979742 scopus 로고    scopus 로고
    • UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish
    • Walsh E.C., and Stainier D.Y. UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish. Science 293 (2001) 1670-1673
    • (2001) Science , vol.293 , pp. 1670-1673
    • Walsh, E.C.1    Stainier, D.Y.2
  • 3
    • 0030746593 scopus 로고    scopus 로고
    • Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling
    • Binari R.C., et al. Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling. Development 124 (1997) 2623-2632
    • (1997) Development , vol.124 , pp. 2623-2632
    • Binari, R.C.1
  • 4
    • 0342299882 scopus 로고    scopus 로고
    • The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis
    • Hacker U., et al. The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis. Development 124 (1997) 3565-3573
    • (1997) Development , vol.124 , pp. 3565-3573
    • Hacker, U.1
  • 5
    • 0030885710 scopus 로고    scopus 로고
    • Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila
    • Haerry T.E., et al. Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila. Development 124 (1997) 3055-3064
    • (1997) Development , vol.124 , pp. 3055-3064
    • Haerry, T.E.1
  • 6
    • 2342440335 scopus 로고    scopus 로고
    • Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation
    • Han C., et al. Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation. Development 131 (2004) 1563-1575
    • (2004) Development , vol.131 , pp. 1563-1575
    • Han, C.1
  • 7
    • 1342341864 scopus 로고    scopus 로고
    • Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans
    • Takei Y., et al. Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans. Development 131 (2004) 73-82
    • (2004) Development , vol.131 , pp. 73-82
    • Takei, Y.1
  • 8
    • 0035929660 scopus 로고    scopus 로고
    • The molecular phenotype of heparan sulfate in the Hs2st-/- mutant mouse
    • Merry C.L., et al. The molecular phenotype of heparan sulfate in the Hs2st-/- mutant mouse. J. Biol. Chem. 276 (2001) 35429-35434
    • (2001) J. Biol. Chem. , vol.276 , pp. 35429-35434
    • Merry, C.L.1
  • 9
    • 0035907351 scopus 로고    scopus 로고
    • Drosophila heparan sulfate 6-O-sulfotransferase (dHS6ST) gene. Structure, expression, and function in the formation of the tracheal system
    • Kamimura K., et al. Drosophila heparan sulfate 6-O-sulfotransferase (dHS6ST) gene. Structure, expression, and function in the formation of the tracheal system. J. Biol. Chem. 276 (2001) 17014-17021
    • (2001) J. Biol. Chem. , vol.276 , pp. 17014-17021
    • Kamimura, K.1
  • 10
    • 0035979765 scopus 로고    scopus 로고
    • Regulation of Wnt signaling and embryo patterning by an extracellular sulfatase
    • Dhoot G.K., et al. Regulation of Wnt signaling and embryo patterning by an extracellular sulfatase. Science 293 (2001) 1663-1666
    • (2001) Science , vol.293 , pp. 1663-1666
    • Dhoot, G.K.1
  • 11
    • 33846150651 scopus 로고    scopus 로고
    • Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase, Sulf2
    • Lum D.H., et al. Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase, Sulf2. Mol Cell Biol 27 (2007) 678-688
    • (2007) Mol Cell Biol , vol.27 , pp. 678-688
    • Lum, D.H.1
  • 12
    • 33751083837 scopus 로고    scopus 로고
    • Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity
    • Lamanna W.C., et al. Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity. Biochem. J. 400 (2006) 63-73
    • (2006) Biochem. J. , vol.400 , pp. 63-73
    • Lamanna, W.C.1
  • 13
    • 0034663225 scopus 로고    scopus 로고
    • Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice
    • Lin X., et al. Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice. Dev. Biol. 224 (2000) 299-311
    • (2000) Dev. Biol. , vol.224 , pp. 299-311
    • Lin, X.1
  • 14
    • 2942538442 scopus 로고    scopus 로고
    • Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification
    • Koziel L., et al. Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification. Dev. Cell 6 (2004) 801-813
    • (2004) Dev. Cell , vol.6 , pp. 801-813
    • Koziel, L.1
  • 15
    • 0030464004 scopus 로고    scopus 로고
    • Jaw and branchial arch mutants in zebrafish I: branchial arches
    • Schilling T.F., et al. Jaw and branchial arch mutants in zebrafish I: branchial arches. Development 123 (1996) 329-344
    • (1996) Development , vol.123 , pp. 329-344
    • Schilling, T.F.1
  • 16
    • 28844441671 scopus 로고    scopus 로고
    • HSPG synthesis by zebrafish Ext2 and Extl3 is required for Fgf10 signalling during limb development
    • Norton W.H., et al. HSPG synthesis by zebrafish Ext2 and Extl3 is required for Fgf10 signalling during limb development. Development 132 (2005) 4963-4973
    • (2005) Development , vol.132 , pp. 4963-4973
    • Norton, W.H.1
  • 17
    • 0033951768 scopus 로고    scopus 로고
    • FGFs, heparan sulfate and FGFRs: complex interactions essential for development
    • Ornitz D.M. FGFs, heparan sulfate and FGFRs: complex interactions essential for development. Bioessays 22 (2000) 108-112
    • (2000) Bioessays , vol.22 , pp. 108-112
    • Ornitz, D.M.1
  • 18
    • 0035937147 scopus 로고    scopus 로고
    • Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4
    • Aikawa J., et al. Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4. J. Biol. Chem. 276 (2001) 5876-5882
    • (2001) J. Biol. Chem. , vol.276 , pp. 5876-5882
    • Aikawa, J.1
  • 19
    • 0032851160 scopus 로고    scopus 로고
    • Functions of cell surface heparan sulfate proteoglycans
    • Bernfield M., et al. Functions of cell surface heparan sulfate proteoglycans. Annu. Rev. Biochem. 68 (1999) 729-777
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 729-777
    • Bernfield, M.1
  • 20
    • 12344310615 scopus 로고    scopus 로고
    • Functions of heparan sulfate proteoglycans in cell signaling during development
    • Lin X. Functions of heparan sulfate proteoglycans in cell signaling during development. Development 131 (2004) 6009-6021
    • (2004) Development , vol.131 , pp. 6009-6021
    • Lin, X.1
  • 21
    • 0034956917 scopus 로고    scopus 로고
    • Heparan sulfate: lessons from knockout mice
    • Forsberg E., and Kjellen L. Heparan sulfate: lessons from knockout mice. J. Clin. Invest. 108 (2001) 175-180
    • (2001) J. Clin. Invest. , vol.108 , pp. 175-180
    • Forsberg, E.1    Kjellen, L.2
  • 22
    • 0033584326 scopus 로고    scopus 로고
    • Heparin is essential for the storage of specific granule proteases in mast cells
    • Humphries D.E., et al. Heparin is essential for the storage of specific granule proteases in mast cells. Nature 400 (1999) 769-772
    • (1999) Nature , vol.400 , pp. 769-772
    • Humphries, D.E.1
  • 23
    • 0037137477 scopus 로고    scopus 로고
    • Heparan sulfate and development: differential roles of the N-acetylglucosamine N-deacetylase/N-sulfotransferase isozymes
    • Grobe K., et al. Heparan sulfate and development: differential roles of the N-acetylglucosamine N-deacetylase/N-sulfotransferase isozymes. Biochim. Biophys. Acta 1573 (2002) 209-215
    • (2002) Biochim. Biophys. Acta , vol.1573 , pp. 209-215
    • Grobe, K.1
  • 24
    • 0032526145 scopus 로고    scopus 로고
    • Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase
    • Bullock S.L., et al. Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase. Genes Dev. 12 (1998) 1894-1906
    • (1998) Genes Dev. , vol.12 , pp. 1894-1906
    • Bullock, S.L.1
  • 25
    • 0021349043 scopus 로고
    • Biosynthesis of heparin. Substrate specificity of heparosan N-sulfate d-glucuronosyl 5-epimerase
    • Jacobsson I., et al. Biosynthesis of heparin. Substrate specificity of heparosan N-sulfate d-glucuronosyl 5-epimerase. J. Biol. Chem. 259 (1984) 1056-1063
    • (1984) J. Biol. Chem. , vol.259 , pp. 1056-1063
    • Jacobsson, I.1
  • 26
    • 2442553816 scopus 로고    scopus 로고
    • Irreversible glucuronyl C5-epimerization in the biosynthesis of heparan sulfate
    • Hagner-McWhirter A., et al. Irreversible glucuronyl C5-epimerization in the biosynthesis of heparan sulfate. J. Biol. Chem. 279 (2004) 14631-14638
    • (2004) J. Biol. Chem. , vol.279 , pp. 14631-14638
    • Hagner-McWhirter, A.1
  • 27
    • 33646345110 scopus 로고    scopus 로고
    • Heparan sulfate C5-epimerase is essential for heparin biosynthesis in mast cells
    • Feyerabend T.B., et al. Heparan sulfate C5-epimerase is essential for heparin biosynthesis in mast cells. Nat. Chem. Biol. 2 (2006) 195-196
    • (2006) Nat. Chem. Biol. , vol.2 , pp. 195-196
    • Feyerabend, T.B.1
  • 28
    • 0027448951 scopus 로고
    • Minimal sequence in heparin/heparan sulfate required for binding of basic fibroblast growth factor
    • Maccarana M., et al. Minimal sequence in heparin/heparan sulfate required for binding of basic fibroblast growth factor. J. Biol. Chem. 268 (1993) 23898-23905
    • (1993) J. Biol. Chem. , vol.268 , pp. 23898-23905
    • Maccarana, M.1
  • 29
    • 33748527145 scopus 로고    scopus 로고
    • Specific and flexible roles of heparan sulfate modifications in Drosophila FGF signaling
    • Kamimura K., et al. Specific and flexible roles of heparan sulfate modifications in Drosophila FGF signaling. J. Cell Biol. 174 (2006) 773-778
    • (2006) J. Cell Biol. , vol.174 , pp. 773-778
    • Kamimura, K.1
  • 30
    • 33746614761 scopus 로고    scopus 로고
    • Interactions between heparan sulfate and proteins: the concept of specificity
    • Kreuger J., et al. Interactions between heparan sulfate and proteins: the concept of specificity. J. Cell Biol. 174 (2006) 323-327
    • (2006) J. Cell Biol. , vol.174 , pp. 323-327
    • Kreuger, J.1
  • 31
    • 2442549670 scopus 로고    scopus 로고
    • Interactions of heparin/heparan sulfate with proteins: appraisal of structural factors and experimental approaches
    • Powell A.K., et al. Interactions of heparin/heparan sulfate with proteins: appraisal of structural factors and experimental approaches. Glycobiology 14 (2004) 17R-30R
    • (2004) Glycobiology , vol.14
    • Powell, A.K.1
  • 32
    • 0037393279 scopus 로고    scopus 로고
    • Biosynthesis of heparan sulphate with diverse structures and functions: two alternatively spliced forms of human heparan sulphate 6-O-sulphotransferase-2 having different expression patterns and properties
    • Habuchi H., et al. Biosynthesis of heparan sulphate with diverse structures and functions: two alternatively spliced forms of human heparan sulphate 6-O-sulphotransferase-2 having different expression patterns and properties. Biochem. J. 371 (2003) 131-142
    • (2003) Biochem. J. , vol.371 , pp. 131-142
    • Habuchi, H.1
  • 33
    • 0041731737 scopus 로고    scopus 로고
    • Heparan sulfate 6-O-sulfotransferase is essential for muscle development in zebrafish
    • Bink R.J., et al. Heparan sulfate 6-O-sulfotransferase is essential for muscle development in zebrafish. J. Biol. Chem. 278 (2003) 31118-31127
    • (2003) J. Biol. Chem. , vol.278 , pp. 31118-31127
    • Bink, R.J.1
  • 34
    • 23944455883 scopus 로고    scopus 로고
    • A unique role for 6-O-sulfation modification in zebrafish vascular development
    • Chen E., et al. A unique role for 6-O-sulfation modification in zebrafish vascular development. Dev. Biol. 284 (2005) 364-376
    • (2005) Dev. Biol. , vol.284 , pp. 364-376
    • Chen, E.1
  • 35
    • 0034723420 scopus 로고    scopus 로고
    • The occurrence of three isoforms of heparan sulfate 6-O-sulfotransferase having different specificities for hexuronic acid adjacent to the targeted N-sulfoglucosamine
    • Habuchi H., et al. The occurrence of three isoforms of heparan sulfate 6-O-sulfotransferase having different specificities for hexuronic acid adjacent to the targeted N-sulfoglucosamine. J. Biol. Chem. 275 (2000) 2859-2868
    • (2000) J. Biol. Chem. , vol.275 , pp. 2859-2868
    • Habuchi, H.1
  • 36
    • 33646834643 scopus 로고    scopus 로고
    • Overexpression of heparan sulfate 6-O-sulfotransferases in human embryonic kidney 293 cells results in increased N-acetylglucosaminyl 6-O-sulfation
    • Do A.T., et al. Overexpression of heparan sulfate 6-O-sulfotransferases in human embryonic kidney 293 cells results in increased N-acetylglucosaminyl 6-O-sulfation. J. Biol. Chem. 281 (2006) 5348-5356
    • (2006) J. Biol. Chem. , vol.281 , pp. 5348-5356
    • Do, A.T.1
  • 37
    • 0035997376 scopus 로고    scopus 로고
    • Order out of chaos: assembly of ligand binding sites in heparan sulfate
    • Esko J.D., and Selleck S.B. Order out of chaos: assembly of ligand binding sites in heparan sulfate. Annu. Rev. Biochem. 71 (2002) 435-471
    • (2002) Annu. Rev. Biochem. , vol.71 , pp. 435-471
    • Esko, J.D.1    Selleck, S.B.2
  • 38
    • 0033215527 scopus 로고    scopus 로고
    • A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry
    • Shukla D., et al. A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry. Cell 99 (1999) 13-22
    • (1999) Cell , vol.99 , pp. 13-22
    • Shukla, D.1
  • 39
    • 0035807780 scopus 로고    scopus 로고
    • Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs
    • Ye S., et al. Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs. Biochemistry 40 (2001) 14429-14439
    • (2001) Biochemistry , vol.40 , pp. 14429-14439
    • Ye, S.1
  • 40
    • 0037837506 scopus 로고    scopus 로고
    • 1976-1983, a critical period in the history of heparin: the discovery of the antithrombin binding site
    • Petitou M., et al. 1976-1983, a critical period in the history of heparin: the discovery of the antithrombin binding site. Biochimie 85 (2003) 83-89
    • (2003) Biochimie , vol.85 , pp. 83-89
    • Petitou, M.1
  • 41
    • 0345471071 scopus 로고    scopus 로고
    • Normal levels of anticoagulant heparan sulfate are not essential for normal hemostasis
    • HajMohammadi S., et al. Normal levels of anticoagulant heparan sulfate are not essential for normal hemostasis. J. Clin. Invest. 111 (2003) 989-999
    • (2003) J. Clin. Invest. , vol.111 , pp. 989-999
    • HajMohammadi, S.1
  • 42
    • 0041671071 scopus 로고    scopus 로고
    • QSulf1 remodels the 6-O-sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling
    • Ai X., et al. QSulf1 remodels the 6-O-sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling. J. Cell Biol. 162 (2003) 341-351
    • (2003) J. Cell Biol. , vol.162 , pp. 341-351
    • Ai, X.1
  • 43
    • 33646188185 scopus 로고    scopus 로고
    • Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2
    • Ai X., et al. Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2. J. Biol. Chem. 281 (2006) 4969-4976
    • (2006) J. Biol. Chem. , vol.281 , pp. 4969-4976
    • Ai, X.1
  • 44
    • 1842737772 scopus 로고    scopus 로고
    • QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis
    • Wang S., et al. QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 4833-4838
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 4833-4838
    • Wang, S.1
  • 45
    • 33744541875 scopus 로고    scopus 로고
    • SULF1 inhibits tumor growth and potentiates the effects of histone deacetylase inhibitors in hepatocellular carcinoma
    • Lai J.P., et al. SULF1 inhibits tumor growth and potentiates the effects of histone deacetylase inhibitors in hepatocellular carcinoma. Gastroenterology 130 (2006) 2130-2144
    • (2006) Gastroenterology , vol.130 , pp. 2130-2144
    • Lai, J.P.1
  • 46
    • 33644658017 scopus 로고    scopus 로고
    • Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer
    • Morimoto-Tomita M., et al. Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer. Neoplasia 7 (2005) 1001-1010
    • (2005) Neoplasia , vol.7 , pp. 1001-1010
    • Morimoto-Tomita, M.1
  • 47
    • 27744479221 scopus 로고    scopus 로고
    • Regulation of vascular smooth muscle cell proliferation, migration and death by heparan sulfate 6-O-endosulfatase1
    • Sala-Newby G.B., et al. Regulation of vascular smooth muscle cell proliferation, migration and death by heparan sulfate 6-O-endosulfatase1. FEBS Lett. 579 (2005) 6493-6498
    • (2005) FEBS Lett. , vol.579 , pp. 6493-6498
    • Sala-Newby, G.B.1
  • 48
    • 33846031152 scopus 로고    scopus 로고
    • Enzymatically active N-deacetylase/N-sulfotransferase-2 is present in liver but does not contribute to heparan sulfate N-sulfation
    • Ledin J., et al. Enzymatically active N-deacetylase/N-sulfotransferase-2 is present in liver but does not contribute to heparan sulfate N-sulfation. J. Biol. Chem. 281 (2006) 35727-35734
    • (2006) J. Biol. Chem. , vol.281 , pp. 35727-35734
    • Ledin, J.1
  • 49
    • 0035818480 scopus 로고    scopus 로고
    • Enzyme interactions in heparan sulfate biosynthesis: uronosyl 5-epimerase and 2-O-sulfotransferase interact in vivo
    • Pinhal M.A., et al. Enzyme interactions in heparan sulfate biosynthesis: uronosyl 5-epimerase and 2-O-sulfotransferase interact in vivo. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 12984-12989
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 12984-12989
    • Pinhal, M.A.1
  • 50
    • 0034278432 scopus 로고    scopus 로고
    • The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis
    • Senay C., et al. The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis. EMBO Rep. 1 (2000) 282-286
    • (2000) EMBO Rep. , vol.1 , pp. 282-286
    • Senay, C.1
  • 51
    • 33644977975 scopus 로고    scopus 로고
    • VEGF165-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by K5 lyase
    • Robinson C.J., et al. VEGF165-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by K5 lyase. J. Biol. Chem. 281 (2006) 1731-1740
    • (2006) J. Biol. Chem. , vol.281 , pp. 1731-1740
    • Robinson, C.J.1
  • 52
    • 33644657201 scopus 로고    scopus 로고
    • HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1
    • 10.1186/1471-2091-7-2 (www.biomedcentral.com)
    • Uchimura K., et al. HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1. BMC Biochem. 7 (2006) 2. http://www.biomedcentral.com/ 10.1186/1471-2091-7-2 (www.biomedcentral.com)
    • (2006) BMC Biochem. , vol.7 , pp. 2
    • Uchimura, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.