-
2
-
-
0035979742
-
UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish
-
Walsh E.C., and Stainier D.Y. UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish. Science 293 (2001) 1670-1673
-
(2001)
Science
, vol.293
, pp. 1670-1673
-
-
Walsh, E.C.1
Stainier, D.Y.2
-
3
-
-
0030746593
-
Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling
-
Binari R.C., et al. Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling. Development 124 (1997) 2623-2632
-
(1997)
Development
, vol.124
, pp. 2623-2632
-
-
Binari, R.C.1
-
4
-
-
0342299882
-
The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis
-
Hacker U., et al. The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis. Development 124 (1997) 3565-3573
-
(1997)
Development
, vol.124
, pp. 3565-3573
-
-
Hacker, U.1
-
5
-
-
0030885710
-
Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila
-
Haerry T.E., et al. Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila. Development 124 (1997) 3055-3064
-
(1997)
Development
, vol.124
, pp. 3055-3064
-
-
Haerry, T.E.1
-
6
-
-
2342440335
-
Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation
-
Han C., et al. Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation. Development 131 (2004) 1563-1575
-
(2004)
Development
, vol.131
, pp. 1563-1575
-
-
Han, C.1
-
7
-
-
1342341864
-
Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans
-
Takei Y., et al. Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans. Development 131 (2004) 73-82
-
(2004)
Development
, vol.131
, pp. 73-82
-
-
Takei, Y.1
-
8
-
-
0035929660
-
The molecular phenotype of heparan sulfate in the Hs2st-/- mutant mouse
-
Merry C.L., et al. The molecular phenotype of heparan sulfate in the Hs2st-/- mutant mouse. J. Biol. Chem. 276 (2001) 35429-35434
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35429-35434
-
-
Merry, C.L.1
-
9
-
-
0035907351
-
Drosophila heparan sulfate 6-O-sulfotransferase (dHS6ST) gene. Structure, expression, and function in the formation of the tracheal system
-
Kamimura K., et al. Drosophila heparan sulfate 6-O-sulfotransferase (dHS6ST) gene. Structure, expression, and function in the formation of the tracheal system. J. Biol. Chem. 276 (2001) 17014-17021
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 17014-17021
-
-
Kamimura, K.1
-
10
-
-
0035979765
-
Regulation of Wnt signaling and embryo patterning by an extracellular sulfatase
-
Dhoot G.K., et al. Regulation of Wnt signaling and embryo patterning by an extracellular sulfatase. Science 293 (2001) 1663-1666
-
(2001)
Science
, vol.293
, pp. 1663-1666
-
-
Dhoot, G.K.1
-
11
-
-
33846150651
-
Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase, Sulf2
-
Lum D.H., et al. Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase, Sulf2. Mol Cell Biol 27 (2007) 678-688
-
(2007)
Mol Cell Biol
, vol.27
, pp. 678-688
-
-
Lum, D.H.1
-
12
-
-
33751083837
-
Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity
-
Lamanna W.C., et al. Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity. Biochem. J. 400 (2006) 63-73
-
(2006)
Biochem. J.
, vol.400
, pp. 63-73
-
-
Lamanna, W.C.1
-
13
-
-
0034663225
-
Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice
-
Lin X., et al. Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice. Dev. Biol. 224 (2000) 299-311
-
(2000)
Dev. Biol.
, vol.224
, pp. 299-311
-
-
Lin, X.1
-
14
-
-
2942538442
-
Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification
-
Koziel L., et al. Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification. Dev. Cell 6 (2004) 801-813
-
(2004)
Dev. Cell
, vol.6
, pp. 801-813
-
-
Koziel, L.1
-
15
-
-
0030464004
-
Jaw and branchial arch mutants in zebrafish I: branchial arches
-
Schilling T.F., et al. Jaw and branchial arch mutants in zebrafish I: branchial arches. Development 123 (1996) 329-344
-
(1996)
Development
, vol.123
, pp. 329-344
-
-
Schilling, T.F.1
-
16
-
-
28844441671
-
HSPG synthesis by zebrafish Ext2 and Extl3 is required for Fgf10 signalling during limb development
-
Norton W.H., et al. HSPG synthesis by zebrafish Ext2 and Extl3 is required for Fgf10 signalling during limb development. Development 132 (2005) 4963-4973
-
(2005)
Development
, vol.132
, pp. 4963-4973
-
-
Norton, W.H.1
-
17
-
-
0033951768
-
FGFs, heparan sulfate and FGFRs: complex interactions essential for development
-
Ornitz D.M. FGFs, heparan sulfate and FGFRs: complex interactions essential for development. Bioessays 22 (2000) 108-112
-
(2000)
Bioessays
, vol.22
, pp. 108-112
-
-
Ornitz, D.M.1
-
18
-
-
0035937147
-
Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4
-
Aikawa J., et al. Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4. J. Biol. Chem. 276 (2001) 5876-5882
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 5876-5882
-
-
Aikawa, J.1
-
19
-
-
0032851160
-
Functions of cell surface heparan sulfate proteoglycans
-
Bernfield M., et al. Functions of cell surface heparan sulfate proteoglycans. Annu. Rev. Biochem. 68 (1999) 729-777
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 729-777
-
-
Bernfield, M.1
-
20
-
-
12344310615
-
Functions of heparan sulfate proteoglycans in cell signaling during development
-
Lin X. Functions of heparan sulfate proteoglycans in cell signaling during development. Development 131 (2004) 6009-6021
-
(2004)
Development
, vol.131
, pp. 6009-6021
-
-
Lin, X.1
-
21
-
-
0034956917
-
Heparan sulfate: lessons from knockout mice
-
Forsberg E., and Kjellen L. Heparan sulfate: lessons from knockout mice. J. Clin. Invest. 108 (2001) 175-180
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 175-180
-
-
Forsberg, E.1
Kjellen, L.2
-
22
-
-
0033584326
-
Heparin is essential for the storage of specific granule proteases in mast cells
-
Humphries D.E., et al. Heparin is essential for the storage of specific granule proteases in mast cells. Nature 400 (1999) 769-772
-
(1999)
Nature
, vol.400
, pp. 769-772
-
-
Humphries, D.E.1
-
23
-
-
0037137477
-
Heparan sulfate and development: differential roles of the N-acetylglucosamine N-deacetylase/N-sulfotransferase isozymes
-
Grobe K., et al. Heparan sulfate and development: differential roles of the N-acetylglucosamine N-deacetylase/N-sulfotransferase isozymes. Biochim. Biophys. Acta 1573 (2002) 209-215
-
(2002)
Biochim. Biophys. Acta
, vol.1573
, pp. 209-215
-
-
Grobe, K.1
-
24
-
-
0032526145
-
Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase
-
Bullock S.L., et al. Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase. Genes Dev. 12 (1998) 1894-1906
-
(1998)
Genes Dev.
, vol.12
, pp. 1894-1906
-
-
Bullock, S.L.1
-
25
-
-
0021349043
-
Biosynthesis of heparin. Substrate specificity of heparosan N-sulfate d-glucuronosyl 5-epimerase
-
Jacobsson I., et al. Biosynthesis of heparin. Substrate specificity of heparosan N-sulfate d-glucuronosyl 5-epimerase. J. Biol. Chem. 259 (1984) 1056-1063
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 1056-1063
-
-
Jacobsson, I.1
-
26
-
-
2442553816
-
Irreversible glucuronyl C5-epimerization in the biosynthesis of heparan sulfate
-
Hagner-McWhirter A., et al. Irreversible glucuronyl C5-epimerization in the biosynthesis of heparan sulfate. J. Biol. Chem. 279 (2004) 14631-14638
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 14631-14638
-
-
Hagner-McWhirter, A.1
-
27
-
-
33646345110
-
Heparan sulfate C5-epimerase is essential for heparin biosynthesis in mast cells
-
Feyerabend T.B., et al. Heparan sulfate C5-epimerase is essential for heparin biosynthesis in mast cells. Nat. Chem. Biol. 2 (2006) 195-196
-
(2006)
Nat. Chem. Biol.
, vol.2
, pp. 195-196
-
-
Feyerabend, T.B.1
-
28
-
-
0027448951
-
Minimal sequence in heparin/heparan sulfate required for binding of basic fibroblast growth factor
-
Maccarana M., et al. Minimal sequence in heparin/heparan sulfate required for binding of basic fibroblast growth factor. J. Biol. Chem. 268 (1993) 23898-23905
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 23898-23905
-
-
Maccarana, M.1
-
29
-
-
33748527145
-
Specific and flexible roles of heparan sulfate modifications in Drosophila FGF signaling
-
Kamimura K., et al. Specific and flexible roles of heparan sulfate modifications in Drosophila FGF signaling. J. Cell Biol. 174 (2006) 773-778
-
(2006)
J. Cell Biol.
, vol.174
, pp. 773-778
-
-
Kamimura, K.1
-
30
-
-
33746614761
-
Interactions between heparan sulfate and proteins: the concept of specificity
-
Kreuger J., et al. Interactions between heparan sulfate and proteins: the concept of specificity. J. Cell Biol. 174 (2006) 323-327
-
(2006)
J. Cell Biol.
, vol.174
, pp. 323-327
-
-
Kreuger, J.1
-
31
-
-
2442549670
-
Interactions of heparin/heparan sulfate with proteins: appraisal of structural factors and experimental approaches
-
Powell A.K., et al. Interactions of heparin/heparan sulfate with proteins: appraisal of structural factors and experimental approaches. Glycobiology 14 (2004) 17R-30R
-
(2004)
Glycobiology
, vol.14
-
-
Powell, A.K.1
-
32
-
-
0037393279
-
Biosynthesis of heparan sulphate with diverse structures and functions: two alternatively spliced forms of human heparan sulphate 6-O-sulphotransferase-2 having different expression patterns and properties
-
Habuchi H., et al. Biosynthesis of heparan sulphate with diverse structures and functions: two alternatively spliced forms of human heparan sulphate 6-O-sulphotransferase-2 having different expression patterns and properties. Biochem. J. 371 (2003) 131-142
-
(2003)
Biochem. J.
, vol.371
, pp. 131-142
-
-
Habuchi, H.1
-
33
-
-
0041731737
-
Heparan sulfate 6-O-sulfotransferase is essential for muscle development in zebrafish
-
Bink R.J., et al. Heparan sulfate 6-O-sulfotransferase is essential for muscle development in zebrafish. J. Biol. Chem. 278 (2003) 31118-31127
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31118-31127
-
-
Bink, R.J.1
-
34
-
-
23944455883
-
A unique role for 6-O-sulfation modification in zebrafish vascular development
-
Chen E., et al. A unique role for 6-O-sulfation modification in zebrafish vascular development. Dev. Biol. 284 (2005) 364-376
-
(2005)
Dev. Biol.
, vol.284
, pp. 364-376
-
-
Chen, E.1
-
35
-
-
0034723420
-
The occurrence of three isoforms of heparan sulfate 6-O-sulfotransferase having different specificities for hexuronic acid adjacent to the targeted N-sulfoglucosamine
-
Habuchi H., et al. The occurrence of three isoforms of heparan sulfate 6-O-sulfotransferase having different specificities for hexuronic acid adjacent to the targeted N-sulfoglucosamine. J. Biol. Chem. 275 (2000) 2859-2868
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2859-2868
-
-
Habuchi, H.1
-
36
-
-
33646834643
-
Overexpression of heparan sulfate 6-O-sulfotransferases in human embryonic kidney 293 cells results in increased N-acetylglucosaminyl 6-O-sulfation
-
Do A.T., et al. Overexpression of heparan sulfate 6-O-sulfotransferases in human embryonic kidney 293 cells results in increased N-acetylglucosaminyl 6-O-sulfation. J. Biol. Chem. 281 (2006) 5348-5356
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 5348-5356
-
-
Do, A.T.1
-
37
-
-
0035997376
-
Order out of chaos: assembly of ligand binding sites in heparan sulfate
-
Esko J.D., and Selleck S.B. Order out of chaos: assembly of ligand binding sites in heparan sulfate. Annu. Rev. Biochem. 71 (2002) 435-471
-
(2002)
Annu. Rev. Biochem.
, vol.71
, pp. 435-471
-
-
Esko, J.D.1
Selleck, S.B.2
-
38
-
-
0033215527
-
A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry
-
Shukla D., et al. A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry. Cell 99 (1999) 13-22
-
(1999)
Cell
, vol.99
, pp. 13-22
-
-
Shukla, D.1
-
39
-
-
0035807780
-
Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs
-
Ye S., et al. Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs. Biochemistry 40 (2001) 14429-14439
-
(2001)
Biochemistry
, vol.40
, pp. 14429-14439
-
-
Ye, S.1
-
40
-
-
0037837506
-
1976-1983, a critical period in the history of heparin: the discovery of the antithrombin binding site
-
Petitou M., et al. 1976-1983, a critical period in the history of heparin: the discovery of the antithrombin binding site. Biochimie 85 (2003) 83-89
-
(2003)
Biochimie
, vol.85
, pp. 83-89
-
-
Petitou, M.1
-
41
-
-
0345471071
-
Normal levels of anticoagulant heparan sulfate are not essential for normal hemostasis
-
HajMohammadi S., et al. Normal levels of anticoagulant heparan sulfate are not essential for normal hemostasis. J. Clin. Invest. 111 (2003) 989-999
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 989-999
-
-
HajMohammadi, S.1
-
42
-
-
0041671071
-
QSulf1 remodels the 6-O-sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling
-
Ai X., et al. QSulf1 remodels the 6-O-sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling. J. Cell Biol. 162 (2003) 341-351
-
(2003)
J. Cell Biol.
, vol.162
, pp. 341-351
-
-
Ai, X.1
-
43
-
-
33646188185
-
Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2
-
Ai X., et al. Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2. J. Biol. Chem. 281 (2006) 4969-4976
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 4969-4976
-
-
Ai, X.1
-
44
-
-
1842737772
-
QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis
-
Wang S., et al. QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 4833-4838
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 4833-4838
-
-
Wang, S.1
-
45
-
-
33744541875
-
SULF1 inhibits tumor growth and potentiates the effects of histone deacetylase inhibitors in hepatocellular carcinoma
-
Lai J.P., et al. SULF1 inhibits tumor growth and potentiates the effects of histone deacetylase inhibitors in hepatocellular carcinoma. Gastroenterology 130 (2006) 2130-2144
-
(2006)
Gastroenterology
, vol.130
, pp. 2130-2144
-
-
Lai, J.P.1
-
46
-
-
33644658017
-
Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer
-
Morimoto-Tomita M., et al. Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer. Neoplasia 7 (2005) 1001-1010
-
(2005)
Neoplasia
, vol.7
, pp. 1001-1010
-
-
Morimoto-Tomita, M.1
-
47
-
-
27744479221
-
Regulation of vascular smooth muscle cell proliferation, migration and death by heparan sulfate 6-O-endosulfatase1
-
Sala-Newby G.B., et al. Regulation of vascular smooth muscle cell proliferation, migration and death by heparan sulfate 6-O-endosulfatase1. FEBS Lett. 579 (2005) 6493-6498
-
(2005)
FEBS Lett.
, vol.579
, pp. 6493-6498
-
-
Sala-Newby, G.B.1
-
48
-
-
33846031152
-
Enzymatically active N-deacetylase/N-sulfotransferase-2 is present in liver but does not contribute to heparan sulfate N-sulfation
-
Ledin J., et al. Enzymatically active N-deacetylase/N-sulfotransferase-2 is present in liver but does not contribute to heparan sulfate N-sulfation. J. Biol. Chem. 281 (2006) 35727-35734
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 35727-35734
-
-
Ledin, J.1
-
49
-
-
0035818480
-
Enzyme interactions in heparan sulfate biosynthesis: uronosyl 5-epimerase and 2-O-sulfotransferase interact in vivo
-
Pinhal M.A., et al. Enzyme interactions in heparan sulfate biosynthesis: uronosyl 5-epimerase and 2-O-sulfotransferase interact in vivo. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 12984-12989
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 12984-12989
-
-
Pinhal, M.A.1
-
50
-
-
0034278432
-
The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis
-
Senay C., et al. The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis. EMBO Rep. 1 (2000) 282-286
-
(2000)
EMBO Rep.
, vol.1
, pp. 282-286
-
-
Senay, C.1
-
51
-
-
33644977975
-
VEGF165-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by K5 lyase
-
Robinson C.J., et al. VEGF165-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by K5 lyase. J. Biol. Chem. 281 (2006) 1731-1740
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 1731-1740
-
-
Robinson, C.J.1
-
52
-
-
33644657201
-
HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1
-
10.1186/1471-2091-7-2 (www.biomedcentral.com)
-
Uchimura K., et al. HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1. BMC Biochem. 7 (2006) 2. http://www.biomedcentral.com/ 10.1186/1471-2091-7-2 (www.biomedcentral.com)
-
(2006)
BMC Biochem.
, vol.7
, pp. 2
-
-
Uchimura, K.1
|