Activation mechanism of recombinant Der p 3 allergen zymogen: Contribution of cysteine protease Der p 1 and effect of propeptide glycosylation

Journal of Biological Chemistry

Volumn 283, Issue 45, 2008, Pages 30606-30617

  Dumez, Marie Eve ^a,d   Teller, Nathalie ^a   Mercier, Frédéric ^a   Tanaka, Tetsuya ^b   Vandenberghe, Isabel ^c   Vandenbranden, Michel ^b   Devreese, Bart ^c   Luxen, André ^a   Frère, Jean Marie ^a   Matagne, André ^a,e   Jacquet, Alain ^b   Galleni, Moreno ^a   Chevigné, Andy ^a,b,f  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^c Laboratory of Protein Biochemistry and Protein Engineering   (Belgium)

^d Fonds de la Recherche Pour Les Industries et l'Agriculture   (Belgium)

^e FNRS   (Belgium)

^f FUND FOR SCIENTIFIC RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

DUST; ENZYME ACTIVITY; ESTERIFICATION; GLYCOSYLATION;

ACTIVATION MECHANISMS; CYSTEINE PROTEASES; ENZYMATIC ACTIVITIES; GLYCOSYLATED; HOUSE DUSTS; MAJOR ALLERGENS; MATURATION MECHANISMS; NATURAL ENZYMES; PICHIA PASTORIS; PRIMARY STRUCTURES; PROPEPTIDE; ZYMOGEN ACTIVATIONS;

HOUSES;

CYSTEINE PROTEASE DER P 1; CYSTEINE PROTEASE DER P 3; CYSTEINE PROTEINASE; ENZYME PRECURSOR; PAPAIN; PEPTIDE; TRYPSIN; TRYPTASE; UNCLASSIFIED DRUG;

ARTICLE; DERMATOPHAGOIDES PTERONYSSINUS; ENZYME ACTIVITY; ENZYME INHIBITION; HOUSE DUST; KINETICS; MATURATION; NONHUMAN; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN INTERACTION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, DERMATOPHAGOIDES; CYSTEINE ENDOPEPTIDASES; DERMATOPHAGOIDES PTERONYSSINUS; ENZYME ACTIVATION; ENZYME PRECURSORS; GLYCOSYLATION; RECOMBINANT PROTEINS;

DERMATOPHAGOIDES PTERONYSSINUS; PICHIA PASTORIS; PYROGLYPHIDAE;

EID: 57649219464     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M803041200     Document Type: Article

References (51)

1. Thomas, W., Smith, W. A., Hales, B., Mills, K., and O'Brien, R. (2002) Int. Arch. Allergy Immunol. 129, 1-18
2. Platt-Mills, T., and Chapman, M. (1987) J. Allergy Clin. Immunol. 80, 755-775
3. Stewart, G., Ward, L., Simpson, R., and Thompson, P. (1992) Immunology 75, 29-35
4. Ando, T., Homma, R., Ino, Y., Ito, G., Miyahara, A., Yanagihara, T., Kimura, H., Ikeda, S., Yamakawa, H., Iwaki, M., Okumura, Y., Suko, M., Haida, M., and Okudaira, H. (1993) Clin. Exp. Allergy 23, 777-784
5. Smith, W., and Thomas, W. R. (1996) Int. Arch. Allergy Immunol. 109, 133-140
6. Hales, B. J., Martin, A. C., Pearce, L. J., Laing, I. A., Hayden, C. M., Goldblatt, J., Le Souëf, P. N., and Thomas, W. R. (2006) J. Allergy Clin. Immunol. 118, 361-367
7. Yasueda, H., Mita, H., and Akiyama, K. (1993) Clin. Exp. Allergy 23, 384-390
8. Bennett, B. J., and Thomas, W. R. (1996) Clin. Exp. Allergy 26, 1150-1154
9. King, C., Simpson, R. J., Moritz, R. L., Reed, G. E., Thompson, P. J., and Stewart, G. A. (1996) J. Allergy Clin. Immunol. 98, 739-747
10. Smith, W., Chuna, K., Kuo, M., Rogers, B., and Thomas, W. (1994) Clin. Exp. Allergy 24, 220-228
11. Stewart, G., Kollinger, M., King, C., and Thompson, P. (1994) Allergy (Cph.) 49, 553-560
12. Maruo, K., Akaike, T., Ono, T., Okamoto, T., and Maeda, H. (1997) J. Allergy Clin. Immunol. 100, 253-260
13. Sun, G., Stacey, M., Schmidt, M., Mori, L., and Mattoli, S. (2001) J. Immunol. 167, 1014-1021
14. Lazure, C. (2002) Curr. Pharm. Des. 8, 125-133
15. Vernon, H. (1914) J. Biol. Chem. 8, 494-529
16. Brodrick, J., Largman, C., Johnson, J., and Geokas, M. (1978) J. Biol. Chem. 253, 2732-2736
17. Frick, T., Fernandez-del-Castillo, C., Bimmler, D., and Warshaw, A. (1997) Gut 41, 339-343
18. Chen, J.-M., Kukor, Z., Le Maréchal, C., Toth, M., Tsakiris, L., Raguenes, O., Ferec, C., and Sahin-Toth, M. (2003) Mol. Biol. Evol. 20, 1767-1777
19. Schechter, I., and Berger, A. (1967) Biochem. Biophys. Res. Commun. 27, 157-162
20. Nishiyama, C., Yasuhara, T., Yuuki, T., and Okumura, Y. (1995) FEBS Lett. 377, 62-66
21. Jacquet, A., Magi, M., Petry, H., and Bollen, A. (2002) Clin. Exp. Allergy 32, 1048-1053
22. Stewart, G. A., Thompson, P. J., and Simpson, R. J. (1989) Lancet ii, 154-155; Correction (1989) Lancet ii, 462
23. Chevigné, A., Barumandzadeh, R., Groslambert, S., Cloes, B., Dehareng, D., Filée, P., Marx, J.-C., Frère, J.-M., Matagne, A., Jacquet, A., and Galleni, M. (2007) J. Mol. Biol. 374, 170-185
24. Cheong, N., Yang, L., Lee, B. W., and Chua, K. Y. (2003) Allergy (Cph.) 58, 352-356
25. Ménard, R., Carmenon, E., Takebe, S., Dufour, E., Plouffe, C., Mason, P., and Mort, J. (1998) J. Biol. Chem. 273, 4478-4484
26. Quraishi, O., and Storer, A. C. (2001) J. Biol. Chem. 276, 8118-8124
27. Cha, S. (1975) Biochem. Pharmacol. 24, 2177-2185
28. Morrison, J. F. (1969) Biochim. Biophys. Acta 185, 269-286
29. Morrison, J. F. (1982) Trends Biochem. Sci. 7, 102-105
30. Morrison, J. F., and Stone, S. R. (1985) Comments Mol. Cell. Biophys. 2, 347-368
31. Morrison, J. F., and Walsh, C. T. (1988) Adv. Enzymol. Relat. Areas Mol. Biol. 61, 201-301
32. Lund, O., Nielsen, M., Lundegaard, C., and Worning, P. (2002) CASP5 Conference, Asimolar (CA), Protein Structure Prediction Center, A102-A104, University of California, Davis
33. Kukor, Z., Toth, M., Pal, G., and Sahin-Toth, M. (2002) J. Biol. Chem. 277, 6111-6117
34. Schulz, O., Sewell, H. F., and Shakib, F. (1998) J. Clin. Pathol. (Lond.) 51, 222-231
35. Halfon, S., Baird, T., and Craik, C. (2004) in Handbook of Proteolytic Enzymes (Barrett, A. J., Rawlings, N. D., and Woessner, J. D.) 2nd Ed., pp. 1483-1488, Elsevier Academic Press, New York
36. Kay, J., and Kassell, B. (1971) J. Biol. Chem. 246, 6661-6665
37. van Stokkum, I., Linsdell, H., Hadden, J. M., Haris, P. I., Chapman, D., and Bloemendal, M. (1995) Biochemistry 34, 10508-10518
38. Arrondo, J., and Goni, F. M. (1999) Prog. Biophys. Mol. Biol. 72, 367-405
39. Kukor, Z., Toth, M., and Sahin-Toth, M. (2003) Eur. J. Biochem. 270, 2047-2058
40. Whitcomb, D., Gorry, M. C., Preston, R. A., Furey, W., Sossenheimer, M. J., Ulrich, C. D., Martin, S. P., Gates, L. K., Jr., Amann, S. T., Toskes, P. P., Liddle, R., McGrath, K., Uomo, G., Post, J. C., and Ehrlich, G. D. (1996) Nat. Genet. 14, 141-145
41. Huber, R., and Bode, W. (1978) Acc. Chem. Res. 11, 114-122
42. Fehlhammer, H., Bode, W., and Huber, R. (1977) J. Mol. Biol. 111, 415-438
43. Brünger, A. T., Huber, R., and Karplus, M. (1987) Biochemistry 26, 5153-5162
44. Hedstrom, L., Lin, T.-Y., and Fast, W. (1996) Biochemistry 35, 4515-4523
45. Pasternak, A., Liu, X., Lin, T.-Y., and Hedstrom, L. (1998) Biochemistry 37, 16201-16210
46. Harris, J., Mason, D., Li, J., Burdick, K., Backes, B., Chen, T., Shipway, A., Van Heeke, G., Cough, L., Ghaemmaghami, A., Shakib, F., Debaene, F., and Winssinger, N. (2004) Chem. Biol. 11, 1361-1372
47. Greenbaum, L., Hirshkowitz, A., and Shoichet, I. (1959) J. Biol. Chem. 234, 2885-2890
48. Halangk, W., Lerch, M., Brandt-Nedelev, B., Roth, W., Ruthenbuerger, M., Reinheckel, T., Domschke, W., Lippert, H., Peters, C., and Deussing, J. (2000) J. Clin. Investig. 106, 773-781
49. Szilagyi, L., Kenesi, E., Katona, G., Kaslik, G., Juhasz, G., and Graf, L. (2001) J. Biol. Chem. 276, 24574-24580
50. Takai, T., Mizuuchi, E., Kikuchi, Y., Nagamune, T., Okumura, K., and Ogawa, H. (2006) Int. Arch. Allergy Immunol. 139, 181-187
51. Gombos, L., Kardos, J., Patthy, A., Medveczky, P., Szilagyi, L., Malnasi-Csizmadia, A., and Graf, L. (2008) Biochemistry 47, 1675-1684