Cytosolic phospholipase A2α is targeted to the p47 phox-PX domain of the assembled NADPH oxidase via a novel binding site in its C2 domain

Journal of Biological Chemistry

Volumn 283, Issue 46, 2008, Pages 31898-31908

  Shmelzer, Zeev ^a   Karter, Maria ^a   Eisenstein, Miriam ^b   Leto, Thomas L ^e   Hadad, Nurit ^a   Ben Menahem, David ^a   Gitler, Daniel ^a   Banani, Shirly ^a   Wolach, Baruch ^c   Rotem, Meir ^d   Levy, Rachel ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c MEIR MEDICAL CENTER   (Israel)

^d HAEMEK MEDICAL CENTER   (Israel)

^e NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; BINDING ENERGY; BIOCHEMISTRY; CATALYSTS; CELL MEMBRANES; DOCKING; ENERGY TRANSFER; ENZYMES; FLOW INTERACTIONS; HYDROPHOBICITY; PLANTS (BOTANY); PLASMAS; PROTEINS;

AFFINITY BINDINGS; C2 DOMAINS; COMPUTATIONAL DOCKING; CYTOSOLIC PHOSPHOLIPASE; DOUBLE MUTANTS; HYDROPHOBIC INTERACTIONS; HYDROPHOBIC PEPTIDES; INTERACTION MODELS; LYSATES; NADPH OXIDASES; PHYSICAL INTERACTIONS; PLASMA MEMBRANES; PX DOMAINS; RESONANCE ENERGIES; SINGLE MUTANTS; TRIPLE MUTANTS; TWO DOMAINS;

BINDING SITES;

CYTOSOLIC PHOSPHOLIPASE A2; CYTOSOLIC PHOSPHOLIPASE A2 ALPHA; ISOLEUCINE; PROTEIN P47; PROTEIN P67; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG; CYTOCHROME B; CYTOCHROME B558; NEUTROPHIL CYTOSOLIC FACTOR 1; PHOSPHOLIPASE A2 GROUP IV;

ARTICLE; CELL LYSATE; ENZYME ACTIVITY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GRANULOMATOSIS; HUMAN; HUMAN CELL; HYDROPHOBICITY; MOLECULAR DOCKING; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; PROTEIN TARGETING; BINDING SITE; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; CYTOSOL; ENZYMOLOGY; GENETICS; METABOLISM; PROTEIN QUATERNARY STRUCTURE; PROTEIN TRANSPORT; TUMOR CELL LINE;

BINDING SITES; CELL LINE, TUMOR; CELL MEMBRANE; CYTOCHROME B GROUP; CYTOSOL; GROUP IV PHOSPHOLIPASES A2; HUMANS; MODELS, MOLECULAR; NADPH OXIDASE; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN TRANSPORT;

EID: 57649140940     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M804674200     Document Type: Article

References (49)

1. Leto, T. L. (1999) in Inflammation: Basic Principles and Clinical Correlates (Gallin, J., Snyderman, R., Fearon, D., Haynes, B., and Nathan, C., eds) pp. 769-786, Lippincott, Williams, and Wilkins Press, Baltimore, MD
2. Groemping, Y., and Rittinger, K. (2005) Biochem. J. 386, 401-416
3. Roos, D., de Boer, M., Kuribayashi, F., Meischl, C., Weening, R. S., Segal, A. W., Ahlin, A., Nemet, K., Hossle, J. P., Bernatowska-Matuszkiewicz, E., and Middleton-Price, H. (1996) Blood 87, 1663-1681
4. Heyworth, P. G., Curnutte, J. T., Nauseef, W. M., Volpp, B. D., Pearson, D. W., Rosen, H., and Clark, R. A. (1991) J. Clin. Invest. 87, 352-356
5. Ueyama, T., Kusakabe, T., Karasawa, S., Kawasaki, T., Shimizu, A., Son, J., Leto, T., Miyawaki, A., and Saito, N. (2008) J. Immunol. 181, 629-640
6. Ago, T., Nunoi, H., Ito, T., and Sumimoto, H. (1999) J. Biol. Chem. 274, 33644-33653
7. Sato, T. K., Overduin, M., and Emr, S. D. (2001) Science 294, 1881-1885
8. Kanai, F., Liu, H., Field, S. J., Akbary, H., Matsuo, T., Brown, G. E., Cantley, L. C., and Yaffe, M. B. (2001) Nat. Cell Biol. 3, 675-678
9. Karathanassis, D., Stahelin, R. V., Bravo, J., Perisic, O., Pacold, C. M., Cho, W., and Williams, R. L. (2002) EMBO J. 21, 5057-5068
10. Dusi, S., Donini, M., and Rossi, F. (1996) Biochem. J. 314, 409-412
11. Ueyama, T., Tatsuno, T., Kawasaki, T., Tsujibe, S., Shirai, Y., Sumimoto, H., Leto, T., and Saito, N. (2007) Mol. Biol. Cell 18, 441-454
12. Clark, J. D., Milona, N., and Knopf, J. L. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 7708-7712
13. Nalefski, E. A., Sultzman, L. A., Martin, D. M., Kriz, R. W., Towler, P. S., Knopf, J. L., and Clark, J. D. (1994) J. Biol. Chem. 269, 18239-18249
14. Glover, S., de Carvalho, M. S., Bayburt, T., Jonas, M., Chi, E., Leslie, C.C., and Gelb, M. H. (1995) J. Biol. Chem. 270, 15359-15367
15. Dessen, A., Tang, J., Schmidt, H., Stahl, M., Clark, J. D., Seehra, J., and Somers, W. S. (1999) Cell 97, 349-360
16. Essen, L. O., Perisic, O., Lynch, D. E., Katan, M., and Williams, R. L. (1997) Biochemistry. 36, 2753-2762
17. Ghosh, M., Tucker, D., Burchett, S., and Leslie, C. (2006) Prog. Lipid Res. 45, 487-510
18. Dana, R., Leto, T. L., Malech, H. L., and Levy, R. (1998) J. Biol. Chem. 273, 441-445
19. Lowenthal, A., and Levy, R. (1999) J. Biol. Chem. 274, 21603-21608
20. Pessach, I., Leto, T. L., Malech, H. L., and Levy, R. (2001) J. Biol. Chem. 276, 33495-33503
21. Li, Q., and Cathcart, M. K. (1997) J. Biol. Chem. 272, 2404-2411
22. Bae, Y. S., Kim, Y., Kim, J. H., Lee, T. G., Suh, P. G., and Ryu, S. H. (2000) J. Immunol. 164, 4089-4096
23. O'Dowd, Y. M., El-Benna, J., Perianin, A., and Newsholme, P. (2004) Biochem. Pharmacol. 67, 183-190
24. Rubin, B. B., Downey, G. P., Koh, A., Degousee, N., Ghomashchi, F., Nallan, L., Stefanski, E., Harkin, D. W., Sun, C., Smart, B. P., Lindsay, T. F., Cherepanov, V., Vachon, E., Kelvin, D., Sadilek, M., Brown, G. E., Yaffe, M. B., Plumb, J., Grinstein, S., Glogauer, M., Gelb, M. H., Singer, A., Borregaard, N., Reithmeier, R., Lichtenberger, C., Reinisch, W., Lambeau, G., Arm, J., Tischfield, J., Dienstag, J. L., Schiff, E. R., Mitchell, M., Casey, D. E., Jr., Gitlin, N., Lissoos, T., Gelb, L. D., Condreay, L., Crowther, L., Rubin, M., and Brown, N. (2005) J. Biol. Chem. 280, 7519-7529
25. Shmelzer, Z., Haddad, N., Admon, E., Pessach, I., Leto, T. L., Eitan-Hazan, Z., Hershfinkel, M., and Levy, R. (2003) J. Cell Biol. 162, 683-692
26. Hazan, I., Dana, R., Granot, Y., and Levy, R. (1997) Biochem. J. 326, 867-876
27. Girotti, M., Evans, J. H., Burke, D., and Leslie, C. C. (2004) J. Biol. Chem. 279, 19113-19121
28. Hazan-Halevy, I., Seger, R., and Levy, R. (2000) J. Biol. Chem. 275, 12416-12423
29. Levy, R., Rotrosen, D., Nagauker, O., Leto, T. L., and Malech, H. L. (1990) J. Immunol. 145, 2595-2601
30. Leto, T. L., Adams, A. G., and de Mendez, I. (1994) Proc. Natl. Acad. Sc.i U. S. A. 91, 10650-10654
31. Leto, T. L., Garrett, M. C., Fujii, H., and Nunoi, H. (1991) J. Biol. Chem. 266, 19812-19818
32. Kenworthy, A. K. (2001) Methods 24, 289-296
33. Scaife, R. M., Courtneidge, S. A., and Langdon, W. Y. (2003) J. Cell Sci. 116, 463-473
34. Grinstein, S., and Furuya, W. (1988) J. Biol. Chem. 263, 1779-1783
35. Rotrosen, D., Kleinberg, M. E., Nunoi, H., Leto, T., Gallin, J. I., and Malech, H. L. (1990) J. Biol. Chem. 265, 8745-8750
36. Perisic, O., Fong, S., Lynch, D. E., Bycroft, M., and Williams, R. L. (1998) J. Biol. Chem. 273, 1596-1604
37. Katchalski-Katzir, E., Shariv, I., Eisenstein, M., Friesem, A. A., Aflalo, C., and Vakser, I. A. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 2195-2199
38. Heifetz, A., Katchalski-Katzir, E., and Eisenstein, M. (2002) Protein Sci. 11, 571-587
39. Ben-Zeev, E., and Eisenstein, M. (2003) Proteins 52, 24-27
40. Berchanski, A., Shapira, B., and Eisenstein, M. (2004) Proteins 56, 130-142
41. Ho, S., Hunt, H., Horton, R., Pullen, J., and Pease, L. (1989) Gene (Amst.) 77, 51-59
42. Jares-Erijman, E. A., and Jovin, T. M. (2006) Curr. Opin. Chem. Biol. 10, 409-416
43. Clark, R., Volpp, B., Leidal, K., and Nauseef, W. (1990) J. Clin. Invest. 85, 714-721
44. Zhen, L., Yu, L., and Dinauer, M. C. (1998) J. Biol. Chem. 273, 6575-6581
45. de Mendez, I., Homayounpour, N., and Leto, T. L. (1997) Mol. Cell. Biol. 17, 2177-2185
46. Groemping, Y., Lapouge, K., Smerdon, S. J., and Rittinger, K. (2003) Cell 113, 343-355
47. Yuzawa, S., Ogura, K., Horiuchi, M., Suzuki, N. N., Fujioka, Y., Kataoka, M., Sumimoto, H., and Inagaki, F. (2004) J. Biol. Chem. 279, 29752-29760
48. Das, S., and Cho, W. (2002) J. Biol. Chem. 277, 23838-23846
49. de Mendez, I., Garrett, M. C., Adams, A. G., and Leto, T. L. (1994) J. Biol. Chem. 269, 16326-16332