Silencing c-MYC expression by targeting quadruplex in P1 promoter using locked nucleic acid trap

Biochemistry

Volumn 47, Issue 50, 2008, Pages 13179-13188

  Kumar, Niti ^a   Patowary, Ashok ^a   Sivasubbu, Sridhar ^a   Petersen, Michael ^b   Maiti, Souvik ^a  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BIOACTIVITY; CATALYST ACTIVITY; GENE EXPRESSION; LOW NOISE AMPLIFIERS; MODULATION; MOLECULAR BIOLOGY; MOLECULAR RECOGNITION; NUCLEIC ACIDS; POPULATION STATISTICS; POTASSIUM; SODIUM; THERMODYNAMIC STABILITY;

BASE PAIRINGS; BONDED STRUCTURES; COMPLEMENTARY STRANDS; DUPLEX FORMATIONS; DUPLEX STRUCTURES; DYNAMIC EQUILIBRIUMS; IN-VIVO EXPERIMENTS; INTERCONVERSION; LOCKED NUCLEIC ACIDS; PHARMACOLOGICAL AGENTS; PHYSIOLOGICAL CONDITIONS; SECONDARY STRUCTURES; STRUCTURAL SWITCHES;

AUDIO FREQUENCY AMPLIFIERS;

BUFFER; LOCKED NUCLEIC ACID; POTASSIUM; SODIUM;

ARTICLE; BIOPHYSICS; EMBRYO; GENE EXPRESSION; GENE SILENCING; IN VIVO STUDY; MODULATION; NONHUMAN; ONCOGENE C MYC; PHYSIOLOGY; PRIORITY JOURNAL; PROMOTER REGION; THERMODYNAMICS;

ANIMALS; BASE PAIRING; G-QUADRUPLEXES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE SILENCING; GENE TARGETING; OLIGONUCLEOTIDES; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-MYC; ZEBRAFISH;

EID: 57649134963     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi801064j     Document Type: Article

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