Structural basis for putrescine activation of human S-adenosylmethionine decarboxylase

Biochemistry

Volumn 47, Issue 50, 2008, Pages 13404-13417

  Bale, Shridhar ^a   Lopez, Maria M ^b,c   Makhatadze, George I ^b,c   Fang, Qingming ^b   Pegg, Anthony E ^b   Ealick, Steven E ^a  

^a Department of Obstetrics Gynecology   (United States)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^c RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; BINDING ENERGY; CARBOXYLATION; CENTRIFUGATION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ELECTROSTATICS; ENZYMES; ESTERS; HYDROGEN; HYDROGEN BONDS; X RAY CRYSTALLOGRAPHY;

ACIDIC RESIDUES; ACTIVE SITES; ADOMETDC; ANALYTICAL ULTRACENTRIFUGATION; AROMATIC RESIDUES; AUTOPROCESSING; BINDING STUDIES; BIOSYNTHETIC PATHWAYS; CATALYTIC RESIDUES; CD SPECTROSCOPIES; CONFORMATIONAL CHANGES; COOPERATIVITY; DECARBOXYLASE; DECARBOXYLATION REACTIONS; DIAMINO BUTANES; DIMER INTERFACES; DIMERIC PROTEINS; ELECTROSTATIC EFFECTS; EXTERNAL-; HYDROGEN BONDINGS; HYDROPHILIC RESIDUES; METHYL ESTERS; POLYAMINE; STRUCTURAL BASES; WILD TYPES; X-RAY CRYSTALLOGRAPHIES;

BINDING SITES;

ADENOSYLMETHIONINE DECARBOXYLASE; ASPARTIC ACID; DIMER; GLUTAMINE; HISTIDINE; LYSINE; PUTRESCINE; SERINE;

ALPHA HELIX; ARTICLE; BINDING SITE; CATALYSIS; CIRCULAR DICHROISM; CRYSTAL STRUCTURE; ELECTRICITY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME CONFORMATION; ENZYME STRUCTURE; GENE MUTATION; HUMAN; HYDROPHILICITY; ISOTHERMAL TITRATION CALORIMETRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRUCTURE ANALYSIS; ULTRACENTRIFUGATION; ULTRAVIOLET SPECTROSCOPY; WILD TYPE; X RAY CRYSTALLOGRAPHY;

ADENOSYLMETHIONINE DECARBOXYLASE; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ENZYME ACTIVATION; HUMANS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PUTRESCINE; STATIC ELECTRICITY;

EID: 57649134245     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi801732m     Document Type: Article

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