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Biochemistry

Volumn 40, Issue 32, 2001, Pages 9484-9494

The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase

(7) Tolbert, W D a Ekstrom, J L a Mathews, I I a Secrist III, J A c Kapoor, P b Pegg, A E b Ealick, S E a

a Cornell University ^* (United States)

b PENN STATE MILTON S HERSHEY MEDICAL CENTER (United States)

c SOUTHERN RESEARCH INSTITUTE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COVALENTLY BOUND INHIBITORS;

AMINO ACIDS; BIOSYNTHESIS; ENZYME INHIBITION; ENZYMES; HUMAN ENGINEERING; TUMORS;

BIOCHEMISTRY;

4 AMIDINO 1 INDANONE 2' AMIDINOHYDRAZONE; ADENOSYLMETHIONINE DECARBOXYLASE; DEOXYADENOSINE DERIVATIVE; ENZYME INHIBITOR; MITOGUAZONE;

ARTICLE; CONFORMATIONAL TRANSITION; COVALENT BOND; ELECTRICITY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME INHIBITOR COMPLEX; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; PRIORITY JOURNAL;

ADENOSYLMETHIONINE DECARBOXYLASE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; PUTRESCINE; SUBSTRATE SPECIFICITY;

EID: 0035859868 PISSN: 00062960 EISSN: None Source Type: Journal
DOI: 10.1021/bi010735w Document Type: Article

Times cited : (54)

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