Early RB94-produced cytotoxicity in cancer cells is independent of caspase activation or 50 kb DNA fragmentation

Cancer Gene Therapy

Volumn 16, Issue 1, 2009, Pages 13-19

  Zhou, J ^a   Zhang, X Q ^a   Ashoori, F ^a   McConkey, D J ^a   Knowles, M A ^b   Dong, L ^a   Benedict, W F ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

Bladder cancer; Caspase independent apoptosis; RB94; TUNEL positive

Indexed keywords

ADENOVIRUS VECTOR; APOPTOSIS INDUCING FACTOR; CASPASE; CASPASE 3; CASPASE 9; CYTOCHROME C; DNA FRAGMENT; GENE PRODUCT; PROTEIN RB94; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GENE THERAPY; CELL KILLING; CHROMATIN CONDENSATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENCY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MITOCHONDRION; NICK END LABELING; PRIORITY JOURNAL; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; APOPTOSIS; APOPTOSIS INDUCING FACTOR; CASPASES; CELL LINE, TUMOR; DNA FRAGMENTATION; ENZYME ACTIVATION; GENE THERAPY; HUMANS; IN SITU NICK-END LABELING; PROTEIN ISOFORMS; RETINOBLASTOMA PROTEIN; TRANSDUCTION, GENETIC; URINARY BLADDER NEOPLASMS;

EID: 57649132246     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/cgt.2008.54     Document Type: Article

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