Reduction of myocardial infarction by postischemic administration of the calpain inhibitor A-705253 in comparison to the Na+/H+ exchange inhibitor Cariporide® in isolated perfused rabbit hearts

Biological Chemistry

Volumn 389, Issue 12, 2008, Pages 1505-1512

  Neuhof, Christiane ^a   Fabiunke, Verena ^a   Speth, Maria ^a   Möller, Achim ^b   Fritz, Hans ^c   Tillmanns, Harald ^a   Neuhof, Heinz ^a   Erdogan, Ali ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b ABBOTT GMBH AND CO KG   (Germany)

^c LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Coronary occlusion; Coronary perfusion; Enzyme release; Infarct size; Left ventricular pressure

Indexed keywords

A 705253; CALPAIN; CALPASTATIN; CARIPORIDE; CREATINE KINASE; LACTATE DEHYDROGENASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME RELEASE; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE PRESSURE; HEART PERFUSION; HEART PROTECTION; ISOLATED HEART; LEFT CORONARY ARTERY; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; BENZAMIDES; BLOOD PRESSURE; CALPAIN; CORONARY CIRCULATION; FEMALE; GUANIDINES; HEART; HEART RATE; MALE; MYOCARDIAL INFARCTION; MYOCARDIUM; POTASSIUM; RABBITS; SODIUM-HYDROGEN ANTIPORTER; SULFONES; VENTRICULAR FUNCTION, LEFT;

ORYCTOLAGUS CUNICULUS;

EID: 57649115453     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2008.172     Document Type: Article

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