Pharmacological and biological screening of ascorbigen: Protection against glucose-induced endothelial cell toxicity

Phytotherapy Research

Volumn 22, Issue 12, 2008, Pages 1581-1586

  Joshi, Mandar S ^a,c   Bauer, John A ^a,b,c   Werbovetz, Karl A ^a   Barszcz, Todd ^a   Patil, Popat N ^a  

^a College of Pharmacy ^*  (United States)

^b THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

Author keywords

(L) ascorbic acid; Antioxidant property; Antispasmotic action; Ascorbigen; Cell death protection; Glucose toxicity

Indexed keywords

ANTIOXIDANT; ASCORBIGEN; CARBACHOL; CHOLINESTERASE INHIBITOR; GLUCOSE; HISTAMINE; NITRIC OXIDE; PHENYLEPHRINE; PHYSOSTIGMINE; SEROTONIN; UNCLASSIFIED DRUG;

AGONIST; ANIMAL CELL; ANTIOXIDANT ACTIVITY; ANTIPROTOZOAL ACTIVITY; ARTICLE; BLOOD VESSEL TONE; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SCREENING; ENDOTHELIUM CELL; FROG; GUINEA PIG; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IC 50; ILEUM; IN VITRO STUDY; NONHUMAN; RAT; RECTUS ABDOMINIS MUSCLE; UMBILICAL CORD;

ANIMALS; ANTIOXIDANTS; ANTIPROTOZOAL AGENTS; AORTA; ASCORBIC ACID; BIOLOGICAL PRODUCTS; CARBACHOL; CELL SURVIVAL; CELLS, CULTURED; CYTOPROTECTION; ENDOTHELIAL CELLS; GLUCOSE; GUINEA PIGS; HISTAMINE; HUMANS; ILEUM; INDOLES; LEISHMANIA DONOVANI; MUSCLE CONTRACTION; MUSCLE, SKELETAL; PHENYLEPHRINE; PHYSOSTIGMINE; RANA CATESBEIANA; RATS; SEROTONIN; TRACHEA;

CAVIA;

EID: 57549104737     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2494     Document Type: Article

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