메뉴 건너뛰기




Volumn 15, Issue 9, 2008, Pages 921-931

Reciprocal changes in maternal and fetal metabolism of corticosterone in rat during gestation

Author keywords

Corticosterone; Fetal development; Metabolism of glucocorticoids; Placenta

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; 11BETA HYDROXYSTEROID DEHYDROGENASE 2; CORTICOSTERONE; DEHYDROCORTICOSTERONE; DITHIOTHREITOL; GLUCOCORTICOID; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

EID: 57449104159     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719108319161     Document Type: Article
Times cited : (7)

References (43)
  • 1
    • 2942544589 scopus 로고    scopus 로고
    • Endocrine mechanisms of intrauterine programming
    • Fowden AL, Forhead AJ Endocrine mechanisms of intrauterine programming. Reproduction. 2004 ; 127: 515-526.
    • (2004) Reproduction , vol.127 , pp. 515-526
    • Fowden, A.L.1    Forhead, A.J.2
  • 2
    • 0035924059 scopus 로고    scopus 로고
    • The fetal placental hypothalamic-pituitary-adrenal (HPA) axis, parturition and post natal health
    • Challis JR, Sloboda D., Matthews SG, et al. The fetal placental hypothalamic-pituitary-adrenal (HPA) axis, parturition and post natal health. Mol Cell Endocrinol. 2001 ; 185: 135-144.
    • (2001) Mol Cell Endocrinol , vol.185 , pp. 135-144
    • Challis, J.R.1    Sloboda, D.2    Matthews, S.G.3
  • 3
    • 0242288643 scopus 로고    scopus 로고
    • Late gestation increase in 11β-hydroxysteroid dehydrogenase 1 expression in human fetal membranes: A novel intrauterine source of cortisol
    • Alfaidy N., Li W., MacIntosh T., Yang K., Challis J. Late gestation increase in 11β-hydroxysteroid dehydrogenase 1 expression in human fetal membranes: a novel intrauterine source of cortisol. J Clin Endocrinol Metab. 2003 ; 88: 5033-5038.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 5033-5038
    • Alfaidy, N.1    Li, W.2    MacIntosh, T.3    Yang, K.4    Challis, J.5
  • 4
    • 0030940457 scopus 로고    scopus 로고
    • Placental 11β-hydroxysteroid dehydrogenase: A key regulator of fetal glucocorticoid exposure
    • Benediktsson R., Calder AA, Edwards CR, Seckl JR Placental 11β-hydroxysteroid dehydrogenase: a key regulator of fetal glucocorticoid exposure. Clin Endocrinol. 1997 ; 46: 161-166.
    • (1997) Clin Endocrinol , vol.46 , pp. 161-166
    • Benediktsson, R.1    Calder, A.A.2    Edwards, C.R.3    Seckl, J.R.4
  • 5
    • 0032959843 scopus 로고    scopus 로고
    • Interconversion of cortisol and cortisone by 11β-hydroxysteroid dehydrogenases type 1 and 2 in the perfused human placenta
    • Sun K., Adamson SL, Yang K., Challis JR Interconversion of cortisol and cortisone by 11β-hydroxysteroid dehydrogenases type 1 and 2 in the perfused human placenta. Placenta. 1999 ; 20: 13-19.
    • (1999) Placenta , vol.20 , pp. 13-19
    • Sun, K.1    Adamson, S.L.2    Yang, K.3    Challis, J.R.4
  • 6
    • 28844444674 scopus 로고    scopus 로고
    • Corticosterone transfer and metabolism in the dually perfused rat placenta: Effect of 11β-hydroxysteroid dehydrogenase type 2
    • Staud F., Mazancová K., Mikaík I., Pávek P., Fendrich Z., Pácha J. Corticosterone transfer and metabolism in the dually perfused rat placenta: effect of 11β-hydroxysteroid dehydrogenase type 2. Placenta. 2006 ; 27: 171-180.
    • (2006) Placenta , vol.27 , pp. 171-180
    • Staud, F.1    Mazancová, K.2    Mikaík, I.3    Pávek, P.4    Fendrich, Z.5    Pácha, J.6
  • 7
    • 0015832930 scopus 로고
    • The metabolic clearance rate, blood production, interconversion and transplacental passage of cortisol and cortisone in pregnancy near term
    • Beitins IZ, Bayard F., Ances IG, Kowarski A., Migeon CJ The metabolic clearance rate, blood production, interconversion and transplacental passage of cortisol and cortisone in pregnancy near term. Pediatr Res. 1973 ; 7: 509-519.
    • (1973) Pediatr Res , vol.7 , pp. 509-519
    • Beitins, I.Z.1    Bayard, F.2    Ances, I.G.3    Kowarski, A.4    Migeon, C.J.5
  • 8
    • 0028824557 scopus 로고
    • Placental metabolism of cortisol at mid- and late gestation in swine
    • Klemcke HG Placental metabolism of cortisol at mid- and late gestation in swine. Biol Reprod. 1995 ; 53: 1293-1301.
    • (1995) Biol Reprod , vol.53 , pp. 1293-1301
    • Klemcke, H.G.1
  • 9
    • 0034691133 scopus 로고    scopus 로고
    • Circadian rise in maternal glucocorticoid prevents pulmonary dysplasia in fetal mice with adrenal insufficiency
    • Venihaki M., Carrigan A., Dikkes, Majzoub JA. Circadian rise in maternal glucocorticoid prevents pulmonary dysplasia in fetal mice with adrenal insufficiency. Proc Natl Acad Sci U S A. 2000 ; 97: 7336-7341.
    • (2000) Proc Natl Acad Sci U S a , vol.97 , pp. 7336-7341
    • Venihaki, M.1    Carrigan, A.2    Dikkes Majzoub, J.A.3
  • 10
    • 0035924076 scopus 로고    scopus 로고
    • Glucocorticoid programming of the fetus; Adult phenotypes and molecular mechanisms
    • Seckl JR Glucocorticoid programming of the fetus; adult phenotypes and molecular mechanisms. Mol Cell Endocrinol. 2001 ; 185: 61-71.
    • (2001) Mol Cell Endocrinol , vol.185 , pp. 61-71
    • Seckl, J.R.1
  • 11
    • 34249316880 scopus 로고    scopus 로고
    • Mechanisms of disease: Glucocorticoids, their placental metabolism and fetal "programming" of adult pathophysiology
    • Seckl JR, Holmes MC Mechanisms of disease: glucocorticoids, their placental metabolism and fetal "programming" of adult pathophysiology. Nat Clin Pract Endocrinol Metab. 2007 ; 3: 479-488.
    • (2007) Nat Clin Pract Endocrinol Metab , vol.3 , pp. 479-488
    • Seckl, J.R.1    Holmes, M.C.2
  • 12
  • 13
    • 0031015307 scopus 로고    scopus 로고
    • Differential expression of 11βhydroxysteroid dehydrogenase types 1 and 2 in human placenta and fetal membranes
    • Sun K., Yang K., Challis JR Differential expression of 11βhydroxysteroid dehydrogenase types 1 and 2 in human placenta and fetal membranes. J Clin Endocrinol Metab. 1997 ; 82: 300-305.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 300-305
    • Sun, K.1    Yang, K.2    Challis, J.R.3
  • 14
    • 0030462807 scopus 로고    scopus 로고
    • Developmental increase in expression of the messenger ribonucleic acid and protein levels of 11β-hydroxysteroid dehydrogenase types 1 and 2 in the baboon placenta
    • Pepe GJ, Babischkin JS, Burch MG, Leavitt MG, Albrecht ED Developmental increase in expression of the messenger ribonucleic acid and protein levels of 11β-hydroxysteroid dehydrogenase types 1 and 2 in the baboon placenta. Endocrinology. 1996 ; 137: 5678-5684.
    • (1996) Endocrinology , vol.137 , pp. 5678-5684
    • Pepe, G.J.1    Babischkin, J.S.2    Burch, M.G.3    Leavitt, M.G.4    Albrecht, E.D.5
  • 15
    • 0032588319 scopus 로고    scopus 로고
    • Expression of the 11βhydroxysteroid dehydrogenase types 1 and 2 proteins in human and baboon placental syncytiotrophoblast
    • Pepe GJ, Burch MG Albrecht ED Expression of the 11βhydroxysteroid dehydrogenase types 1 and 2 proteins in human and baboon placental syncytiotrophoblast. Placenta. 1999 ; 20: 575-582.
    • (1999) Placenta , vol.20 , pp. 575-582
    • Pepe, G.J.1    Burch, M.G.2    Albrecht, E.D.3
  • 16
    • 85047676188 scopus 로고    scopus 로고
    • Localization of 11β-hydroxysteroid dehydrogenase type 2 in rat tissues: In situ studies
    • Roland BL, Funder JW Localization of 11β-hydroxysteroid dehydrogenase type 2 in rat tissues: in situ studies. Endocrinology. 1996 ; 137: 1123-1128.
    • (1996) Endocrinology , vol.137 , pp. 1123-1128
    • Roland, B.L.1    Funder, J.W.2
  • 17
    • 0029858184 scopus 로고    scopus 로고
    • Zonal distribution of 11β-hydroxysteroid dehydrogenase types 1 and 2 messenger ribonucleic acid expression in the rat placenta and decidua during late pregnancy
    • Burton PJ, Smith RE, Krozowski ZS, Waddell BJ Zonal distribution of 11β-hydroxysteroid dehydrogenase types 1 and 2 messenger ribonucleic acid expression in the rat placenta and decidua during late pregnancy. Biol Reprod. 1996 ; 55: 1023-1028.
    • (1996) Biol Reprod , vol.55 , pp. 1023-1028
    • Burton, P.J.1    Smith, R.E.2    Krozowski, Z.S.3    Waddell, B.J.4
  • 18
    • 0031734580 scopus 로고    scopus 로고
    • Tissue-specific messenger ribonucleic acid expression of 11β-hydroxysteroid dehydrogenase types 1 and 2 and the glucocorticoid receptor within rat placenta suggests exquisite local control of glucocorticoid action
    • Waddell BJ, Benediktsson R., Brown RW, Seckl JR Tissue-specific messenger ribonucleic acid expression of 11β-hydroxysteroid dehydrogenase types 1 and 2 and the glucocorticoid receptor within rat placenta suggests exquisite local control of glucocorticoid action. Endocrinology. 1998 ; 139: 1517-1523.
    • (1998) Endocrinology , vol.139 , pp. 1517-1523
    • Waddell, B.J.1    Benediktsson, R.2    Brown, R.W.3    Seckl, J.R.4
  • 19
    • 0029670919 scopus 로고    scopus 로고
    • The ontogeny of 11βhydroxysteroid dehydrogenase type 2 and mineralocorticoid receptor gene expression reveal intricate control of glucocorticoid action in development
    • Brown RW, Diaz R., Robson AC, et al. The ontogeny of 11β hydroxysteroid dehydrogenase type 2 and mineralocorticoid receptor gene expression reveal intricate control of glucocorticoid action in development. Endocrinology. 1996 ; 137: 794-797.
    • (1996) Endocrinology , vol.137 , pp. 794-797
    • Brown, R.W.1    Diaz, R.2    Robson, A.C.3
  • 20
    • 0036893651 scopus 로고    scopus 로고
    • Spatial and temporal patterns of expression of 11β-hydroxysteroid dehydrogenase types 1 and 2 messenger RNA and glucocorticoid receptor protein in the murine placenta and uterus during late pregnancy
    • Thompson A., Han VK, Yang K. Spatial and temporal patterns of expression of 11β-hydroxysteroid dehydrogenase types 1 and 2 messenger RNA and glucocorticoid receptor protein in the murine placenta and uterus during late pregnancy. Biol Reprod. 2002 ; 67: 1708-1718.
    • (2002) Biol Reprod , vol.67 , pp. 1708-1718
    • Thompson, A.1    Han, V.K.2    Yang, K.3
  • 21
    • 0029816119 scopus 로고    scopus 로고
    • Porcine placental 11βhydroxysteroid dehydrogenase activity
    • Klemcke HG, Christenson RK Porcine placental 11βhydroxysteroid dehydrogenase activity. Biol Reprod. 1996 ; 55: 217-223.
    • (1996) Biol Reprod , vol.55 , pp. 217-223
    • Klemcke, H.G.1    Christenson, R.K.2
  • 22
    • 0035047054 scopus 로고    scopus 로고
    • Maternal undernutrition during late gestation induces fetal overexposure to glucocorticoids and intrauterine growth retardation, and disturbs the hypothalamo-pituitary adrenal axis in the newborn rat
    • Lesage J., Blondeau B., Grino M., Breant B., Dupouy JP Maternal undernutrition during late gestation induces fetal overexposure to glucocorticoids and intrauterine growth retardation, and disturbs the hypothalamo-pituitary adrenal axis in the newborn rat. Endocrinology. 2001 ; 142: 1692-1702.
    • (2001) Endocrinology , vol.142 , pp. 1692-1702
    • Lesage, J.1    Blondeau, B.2    Grino, M.3    Breant, B.4    Dupouy, J.P.5
  • 23
    • 0038741957 scopus 로고    scopus 로고
    • Placental 11βhydroxysteroid dehydrogenase in Dahl and spontaneously hypertensive rats
    • Mazancová K., Mikaík I., Kunea J., Pácha J. Placental 11βhydroxysteroid dehydrogenase in Dahl and spontaneously hypertensive rats. Am J Hypertens. 2003 ; 16: 401-406.
    • (2003) Am J Hypertens , vol.16 , pp. 401-406
    • Mazancová, K.1    Mikaík, I.2    Kunea, J.3    Pácha, J.4
  • 24
    • 2342612729 scopus 로고    scopus 로고
    • Corticosteroid regulation of colonic ion transport during postnatal development: Methods for corticosteroid analysis
    • Pácha J., Mikaík I., Mrnka L., et al. Corticosteroid regulation of colonic ion transport during postnatal development: methods for corticosteroid analysis. Physiol Res. 2004 ; 53: S63 - S80.
    • (2004) Physiol Res , vol.53
    • Pácha, J.1    Mikaík, I.2    Mrnka, L.3
  • 26
    • 0037060472 scopus 로고    scopus 로고
    • The 11β-hydroxysteroid dehydrogenase type 2 activity in human placenta microsomes is inactivated by zinc and the sulfhydryl modifying reagent N-ethylmaleimide
    • Niu P., Yang K. The 11β-hydroxysteroid dehydrogenase type 2 activity in human placenta microsomes is inactivated by zinc and the sulfhydryl modifying reagent N-ethylmaleimide. Biochim Biophys Acta. 2002 ; 1594: 364-371.
    • (2002) Biochim Biophys Acta , vol.1594 , pp. 364-371
    • Niu, P.1    Yang, K.2
  • 27
    • 0028803568 scopus 로고
    • Actions of placental and fetal adrenal steroid hormones in primate pregnancy
    • Pepe GJ, Albrecht ED Actions of placental and fetal adrenal steroid hormones in primate pregnancy. Endocr Rev. 1995 ; 16: 608-648.
    • (1995) Endocr Rev , vol.16 , pp. 608-648
    • Pepe, G.J.1    Albrecht, E.D.2
  • 28
    • 0032053440 scopus 로고    scopus 로고
    • Distinct ontogeny of glucocorticoid and mineralocorticoid receptor and 11β-hydroxysteroid dehydrogenase types I and II mRNAs in the fetal rat brain suggest a complex control of glucocorticoid actions
    • Diaz R., Brown RW, Seckl JR Distinct ontogeny of glucocorticoid and mineralocorticoid receptor and 11β-hydroxysteroid dehydrogenase types I and II mRNAs in the fetal rat brain suggest a complex control of glucocorticoid actions. J Neurosci. 1998 ; 18: 2570-2580.
    • (1998) J Neurosci , vol.18 , pp. 2570-2580
    • Diaz, R.1    Brown, R.W.2    Seckl, J.R.3
  • 29
    • 0020069985 scopus 로고
    • Responses of rat fetal adrenals to synthetic adrenocorticotrophic hormone and α-melanocyte-stimulating hormone in-vivo and in-vitro studies
    • Dupouy JP Responses of rat fetal adrenals to synthetic adrenocorticotrophic hormone and α-melanocyte-stimulating hormone in-vivo and in-vitro studies. J Endocrinol. 1982 ; 92: 23-30.
    • (1982) J Endocrinol , vol.92 , pp. 23-30
    • Dupouy, J.P.1
  • 30
    • 0025746688 scopus 로고
    • Ontogenesis of 3β-hydroxysteroid dehydrogenase/5-4 isomerase in the rat adrenal as revealed by immunocytochemistry and in situ hybridization
    • Dupont E., Rheaume E., Simard J., Luu-TheV., Labrie F., Pelletier G. Ontogenesis of 3β-hydroxysteroid dehydrogenase/5-4 isomerase in the rat adrenal as revealed by immunocytochemistry and in situ hybridization. Endocrinology. 1991 ; 129: 2687-2692.
    • (1991) Endocrinology , vol.129 , pp. 2687-2692
    • Dupont, E.1    Rheaume, E.2    Simard, J.3    Luu-Thev4    Labrie, F.5    Pelletier, G.6
  • 31
    • 0021751228 scopus 로고
    • Transuteroplacental metabolism of cortisol and cortisone during mid- and late gestation in the baboon
    • Pepe GJ, Albrecht ED Transuteroplacental metabolism of cortisol and cortisone during mid- and late gestation in the baboon. Endocrinology. 1984 ; 115: 1946-1951.
    • (1984) Endocrinology , vol.115 , pp. 1946-1951
    • Pepe, G.J.1    Albrecht, E.D.2
  • 32
    • 0028171669 scopus 로고
    • 11β-Hydroxysteroid dehydrogenase in the rat placenta: Developmental changes and the effects of altered glucocorticoid exposure
    • Burton PJ, Waddell BJ 11β-Hydroxysteroid dehydrogenase in the rat placenta: developmental changes and the effects of altered glucocorticoid exposure. J Endocrinol. 1994 ; 143: 505-513.
    • (1994) J Endocrinol , vol.143 , pp. 505-513
    • Burton, P.J.1    Waddell, B.J.2
  • 33
    • 0031596094 scopus 로고    scopus 로고
    • 11β-Hydroxysteroid dehydrogenase type 2 in human pregnancy and reduced expression in intrauterine growth restriction
    • Shams M., Kilby MD, Somerset DA, et al. 11β-Hydroxysteroid dehydrogenase type 2 in human pregnancy and reduced expression in intrauterine growth restriction. Hum Reprod. 1998 ; 13: 799-804.
    • (1998) Hum Reprod , vol.13 , pp. 799-804
    • Shams, M.1    Kilby, M.D.2    Somerset, D.A.3
  • 34
    • 0034745158 scopus 로고    scopus 로고
    • Ontogeny of 11β-hydroxysteroid dehydrogenase: Activity in the placenta, kidney, colon of fetal rats and rabbits
    • Hundertmark S., Bühler H., Fromm M., et al. Ontogeny of 11β-hydroxysteroid dehydrogenase: activity in the placenta, kidney, colon of fetal rats and rabbits. Horm Metab Res. 2001 ; 33: 78-83.
    • (2001) Horm Metab Res , vol.33 , pp. 78-83
    • Hundertmark, S.1    Bühler, H.2    Fromm, M.3
  • 35
    • 33847083503 scopus 로고    scopus 로고
    • Carbonyl reductases and pluripotent hydroxysteroid dehydrogenases of the short-chain dehydrogenase/ reductase superfamily
    • Hoffmann F., Maser E. Carbonyl reductases and pluripotent hydroxysteroid dehydrogenases of the short-chain dehydrogenase/ reductase superfamily. Drug Metab Rev. 2007 ; 39: 87-144.
    • (2007) Drug Metab Rev , vol.39 , pp. 87-144
    • Hoffmann, F.1    Maser, E.2
  • 36
    • 0041302112 scopus 로고    scopus 로고
    • Regulation of 11β-hydroxysteroid dehydrogenase enzymes in the rat kidney by estradiol
    • Gomez-Sanchez EP, Ganjam V., Chen YJ, et al. Regulation of 11β-hydroxysteroid dehydrogenase enzymes in the rat kidney by estradiol. Am J Physiol. 2003 ; 285: E272 - E279.
    • (2003) Am J Physiol , vol.285
    • Gomez-Sanchez, E.P.1    Ganjam, V.2    Chen, Y.J.3
  • 37
    • 0032587959 scopus 로고    scopus 로고
    • Prostaglandins and leukotriene B4 are potent inhibitors of 11β-hydroxysteroid dehydrogenase type 2 activity in human choriocarcinoma JEG-3 cells
    • Hardy DB, Pereria LE, Yang K. Prostaglandins and leukotriene B4 are potent inhibitors of 11β-hydroxysteroid dehydrogenase type 2 activity in human choriocarcinoma JEG-3 cells. Biol Reprod. 1999 ; 61: 40-45.
    • (1999) Biol Reprod , vol.61 , pp. 40-45
    • Hardy, D.B.1    Pereria, L.E.2    Yang, K.3
  • 38
    • 0034083523 scopus 로고    scopus 로고
    • 11β-Hydroxysteroid dehydrogenase type 1 is a predominant 11β-reductase in the intact perfused rat liver
    • Jamieson PM, Walker BR, Chapman KE, Andrew R., Rossiter S., Seckl JR 11β-Hydroxysteroid dehydrogenase type 1 is a predominant 11β-reductase in the intact perfused rat liver. J Endocrinol. 2000 ; 165: 685-692.
    • (2000) J Endocrinol , vol.165 , pp. 685-692
    • Jamieson, P.M.1    Walker, B.R.2    Chapman, K.E.3    Andrew, R.4    Rossiter, S.5    Seckl, J.R.6
  • 39
    • 0028118922 scopus 로고
    • Gestational age dependence of 11β-hydroxysteroid dehydrogenase and its relationship to the enzymes of phosphatidylcholine synthesis in lung and liver of fetal rat
    • Hundertmark S., Ragosch V., Schein B., et al. Gestational age dependence of 11β-hydroxysteroid dehydrogenase and its relationship to the enzymes of phosphatidylcholine synthesis in lung and liver of fetal rat. Biochim Biophys Acta. 1994 ; 1210: 348-354.
    • (1994) Biochim Biophys Acta , vol.1210 , pp. 348-354
    • Hundertmark, S.1    Ragosch, V.2    Schein, B.3
  • 40
    • 2342540431 scopus 로고    scopus 로고
    • Ontogeny of glucocorticoid receptor and 11β-hydroxysteroid dehydrogenase type-1 gene expression identifies potential critical periods of glucocorticoid susceptibility during development
    • Speirs HJ, Seckl JR, Brown RW Ontogeny of glucocorticoid receptor and 11β-hydroxysteroid dehydrogenase type-1 gene expression identifies potential critical periods of glucocorticoid susceptibility during development. J Endocrinol. 2004 ; 181: 105-116.
    • (2004) J Endocrinol , vol.181 , pp. 105-116
    • Speirs, H.J.1    Seckl, J.R.2    Brown, R.W.3
  • 41
    • 2442473541 scopus 로고    scopus 로고
    • Differential expression of 11β-hydroxysteroid dehydrogenase types 1 and 2 mRNA and glucocorticoid receptor protein during mouse embryonic development
    • Thompson A., Han VK, Yang K. Differential expression of 11β-hydroxysteroid dehydrogenase types 1 and 2 mRNA and glucocorticoid receptor protein during mouse embryonic development. J Steroid Biochem Mol Biol. 2004 ; 88: 367-375.
    • (2004) J Steroid Biochem Mol Biol , vol.88 , pp. 367-375
    • Thompson, A.1    Han, V.K.2    Yang, K.3
  • 42
    • 18844438379 scopus 로고    scopus 로고
    • Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11β-hydroxysteroid dehydrogenase type 1
    • Bujalska IJ, Draper N., Michailidou Z., et al. Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11β-hydroxysteroid dehydrogenase type 1. J Mol Endocrinol. 2005 ; 34: 675-684.
    • (2005) J Mol Endocrinol , vol.34 , pp. 675-684
    • Bujalska, I.J.1    Draper, N.2    Michailidou, Z.3
  • 43
    • 33646007919 scopus 로고    scopus 로고
    • Hexose-6-phosphate dehydrogenase knock-out mice lack 11β- hydroxysteroid dehydrogenase type 1-mediated glucocorticoid generation
    • Lavery GG, Walker EA, Draper N., et al.. Hexose-6-phosphate dehydrogenase knock-out mice lack 11β-hydroxysteroid dehydrogenase type 1-mediated glucocorticoid generation. J Biol Chem. 2006 ; 281: 6546-6551.
    • (2006) J Biol Chem. , vol.281 , pp. 6546-6551
    • Lavery, G.G.1    Walker, E.A.2    Draper, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.