Novel polyion complex micelles for liver-targeted delivery of diammonium glycyrrhizinate: In vitro and in vivo characterization

Journal of Biomedical Materials Research - Part A

Volumn 88, Issue 1, 2009, Pages 140-148

  Ke, Wei Yang ^a   Xin, Ru Li ^a   Zhuo, Li Yang ^a   Ping, Zhu Li ^a   Wang, Fei ^a   Liu, Yan ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Chitosan; Diammonium glycyrrhizinate; In vitro release; Liver targeted micelles; Polyion complex micelles

Indexed keywords

AMINES; CHITIN; CHITOSAN; ETHYLENE; ETHYLENE GLYCOL; GALERKIN METHODS; GLYCOLS; GRAFTING (CHEMICAL); ION EXCHANGE; LIVER; MICELLES; MOTION PICTURE EXPERTS GROUP STANDARDS; PLASMA STABILITY; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; RATS; SIGNAL INTERFERENCE; SUGARS; ZETA POTENTIAL;

AREA UNDER THE CURVES; DIAMMONIUM GLYCYRRHIZINATE; ENCAPSULATION EFFICIENCIES; IN VITRO; IN VITRO DRUG RELEASES; IN VITRO RELEASE; IN-VIVO; MEAN SIZES; METHOXY POLIES; NANOCARRIERS; PHYSICAL STABILITIES; PIC MICELLES; PLASMA CONCENTRATIONS; POLYION COMPLEX MICELLES; TARGETED DELIVERIES; UNIFORM SPHERICAL PARTICLES;

COLLOIDS;

CHITOSAN; DIAMMONIUM GLYCYRRHIZINATE; GLYCYRRHIZIC ACID DERIVATIVE; MACROGOL; NANOCARRIER; POLYMER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BIODEGRADABILITY; CHEMICAL STRUCTURE; DOSE TIME EFFECT RELATION; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG RELEASE; DRUG TARGETING; FOURIER TRANSFORMATION; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; LIGHT SCATTERING; LIVER; MACROMOLECULE; MALE; MICELLE; NONHUMAN; PARTICLE SIZE; PLASMA; POLYION COMPLEX MICELLE; RAT; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

ANIMALS; CHITOSAN; DRUG CARRIERS; DRUG STABILITY; GLYCYRRHIZIC ACID; IONS; LACTOSE; LIVER; MICELLES; NANOPARTICLES; PHARMACOKINETICS; POLYETHYLENE GLYCOLS; POLYMERS; RATS;

EID: 57449096775     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31866     Document Type: Article

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