메뉴 건너뛰기




Volumn 49, Issue 12, 2008, Pages 2383-2386

The hedgehog inhibitor cyclopamine induces apoptosis in leukemic cells in vitro

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPAMINE; CYTOTOXIC AGENT; MESSENGER RNA; RNA; TOMATIDINE; TRANSCRIPTION FACTOR GLI1; UNCLASSIFIED DRUG;

EID: 57449083769     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.1080/10428190802510315     Document Type: Article
Times cited : (13)

References (11)
  • 1
    • 0345059765 scopus 로고    scopus 로고
    • Hedgehog signaling in cancer formation and maintenance
    • Di Magliano, M P and Hebrok, M. (2003) Hedgehog signaling in cancer formation and maintenance. Nat Rev Cancer, 3, pp. 903-911.
    • (2003) Nat Rev Cancer , vol.3 , pp. 903-911
    • Di Magliano, M.P.1    Hebrok, M.2
  • 2
    • 34247635666 scopus 로고    scopus 로고
    • Deregulation and cross talk among Sonic hedgehog, Wnt, Hox and Notch signaling in chronic myeloid leukemia progression
    • Sengupta, A., Banerjee, D., Chandra, S., Banerji, S. K., Ghosh, R. Roy, R. et al. (2007) Deregulation and cross talk among Sonic hedgehog, Wnt, Hox and Notch signaling in chronic myeloid leukemia progression. Leukemia, 21, pp. 949-955.
    • (2007) Leukemia , vol.21 , pp. 949-955
    • Sengupta, A.1    Banerjee, D.2    Chandra, S.3    Banerji, S.K.4    Ghosh, R.5    Roy, R.6
  • 3
    • 0033730931 scopus 로고    scopus 로고
    • Erythroid differentiation in vitro is blocked by cyclopamine, an inhibitor of hedgehog signaling
    • Detmer, K., Walker, A. N., Jenkins, T. M., Steele, T. A. and Dannawi, H. (2000) Erythroid differentiation in vitro is blocked by cyclopamine, an inhibitor of hedgehog signaling. Blood Cells Mol Dis, 26, pp. 360-372.
    • (2000) Blood Cells Mol Dis , vol.26 , pp. 360-372
    • Detmer, K.1    Walker, A.N.2    Jenkins, T.M.3    Steele, T.A.4    Dannawi, H.5
  • 4
    • 4344586961 scopus 로고    scopus 로고
    • Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer
    • Kubo, M., Nakamura, M., Tasaki, A., Yamanaka, N., Nakashima, H. Nomura, M. et al. (2004) Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer. Cancer Res, 64, pp. 6071-6074.
    • (2004) Cancer Res , vol.64 , pp. 6071-6074
    • Kubo, M.1    Nakamura, M.2    Tasaki, A.3    Yamanaka, N.4    Nakashima, H.5    Nomura, M.6
  • 5
    • 2942533929 scopus 로고    scopus 로고
    • Hedgehog signaling in colorectal tumour cells: Induction of apoptosis with cyclopamine treatment
    • Qualtrough, D., Buda, A., Gaffield, W., Williams, A. C. and Paraskeva, C. (2004) Hedgehog signaling in colorectal tumour cells: Induction of apoptosis with cyclopamine treatment. Int J Cancer, 110, pp. 831-837.
    • (2004) Int J Cancer , vol.110 , pp. 831-837
    • Qualtrough, D.1    Buda, A.2    Gaffield, W.3    Williams, A.C.4    Paraskeva, C.5
  • 6
    • 4344659678 scopus 로고    scopus 로고
    • Inhibition of prostate cancer proliferation by interference with Sonic Hedgehog-GLI1 signaling
    • Sanchez, P., Hernandez, A. M., Stecca, B., Kahler, A. J., DeGueme, A. M. Barrett, A. et al. (2004) Inhibition of prostate cancer proliferation by interference with Sonic Hedgehog-GLI1 signaling. Proc Natl Acad Sci USA, 101, pp. 12561-12566.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 12561-12566
    • Sanchez, P.1    Hernandez, A.M.2    Stecca, B.3    Kahler, A.J.4    DeGueme, A.M.5    Barrett, A.6
  • 7
    • 2442596190 scopus 로고    scopus 로고
    • Glycoalkaloids and metabolites inhibit the growth of human colon (HT29) and liver (HepG2) cancer cells
    • Lee, K. R., Kozukue, N., Han, J. S., Park, J. H., Chang, E. Y. Baek, E. J. et al. (2004) Glycoalkaloids and metabolites inhibit the growth of human colon (HT29) and liver (HepG2) cancer cells. J Agric Food Chem, 52, pp. 2832-2839.
    • (2004) J Agric Food Chem , vol.52 , pp. 2832-2839
    • Lee, K.R.1    Kozukue, N.2    Han, J.S.3    Park, J.H.4    Chang, E.Y.5    Baek, E.J.6
  • 8
    • 36549057017 scopus 로고    scopus 로고
    • Inhibition of Osteosarcoma cell proliferation by the Hedgehog-inhibitor Cyclopamine
    • Warzecha, J., Goettig, S., Chow, K. U., Brüning, C., Percic, D. Boehrer, S. et al. (2007) Inhibition of Osteosarcoma cell proliferation by the Hedgehog-inhibitor Cyclopamine. J Chemother, 19, pp. 554-561.
    • (2007) J Chemother , vol.19 , pp. 554-561
    • Warzecha, J.1    Goettig, S.2    Chow, K.U.3    Brüning, C.4    Percic, D.5    Boehrer, S.6
  • 9
    • 34547683699 scopus 로고    scopus 로고
    • Essential role of stromally induced hedgehog signaling in B-cell malignancies
    • Dierks, C., Grbic, J., Zirlik, K., Beigi, R., Englund, N. P. Guo, G. R. et al. (2007) Essential role of stromally induced hedgehog signaling in B-cell malignancies. Nat Med, 13, pp. 944-951.
    • (2007) Nat Med , vol.13 , pp. 944-951
    • Dierks, C.1    Grbic, J.2    Zirlik, K.3    Beigi, R.4    Englund, N.P.5    Guo, G.R.6
  • 10
    • 38049115661 scopus 로고    scopus 로고
    • Protein Kinase A, not Epac, suppresses hedgehog activity and regulates glucocorticoid sensitivity in acute lymphoblastic leukemia cells
    • Ji, Z., Mei, F. C., Johnson, B. H., Thompson, E. B. and Cheng, X. (2007) Protein Kinase A, not Epac, suppresses hedgehog activity and regulates glucocorticoid sensitivity in acute lymphoblastic leukemia cells. J Biol Chem, 282, pp. 37370-37377.
    • (2007) J Biol Chem , vol.282 , pp. 37370-37377
    • Ji, Z.1    Mei, F.C.2    Johnson, B.H.3    Thompson, E.B.4    Cheng, X.5
  • 11
    • 0242268525 scopus 로고    scopus 로고
    • Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
    • Berman, D. M., Karhadkar, S. S., Maitra, A., Montes De Oca, R, Gerstenblith, M. R. Briggs, K. et al. (2003) Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature, 425, pp. 846-851.
    • (2003) Nature , vol.425 , pp. 846-851
    • Berman, D.M.1    Karhadkar, S.S.2    Maitra, A.3    Montes De Oca, R.4    Gerstenblith, M.R.5    Briggs, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.