Insulin-like growth factor stimulation increases radiosensitivity of a pancreatic cancer cell line through endoplasmic reticulum stress under hypoxic conditions

Cancer Science

Volumn 99, Issue 12, 2008, Pages 2395-2401

  Isohashi, Fumiaki ^a,b   Endo, Hiroko ^a   Mukai, Mutsuko ^a   Inoue, Takehiro ^b   Inoue, Masahiro ^a  

^a OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; GENE PRODUCT; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 34; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; SHORT HAIRPIN RNA; SOMATOMEDIN B; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL CYCLE; CELL STRAIN MCF 7; CLONOGENESIS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HYPOXIA; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIOSENSITIVITY; RADIOSENSITIZATION; RNA SPLICING; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CELL HYPOXIA; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM; HUMANS; INSULIN-LIKE GROWTH FACTOR II; PANCREATIC NEOPLASMS; RADIATION TOLERANCE; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SIROLIMUS;

EID: 57349154298     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2008.00970.x     Document Type: Article

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