Petroleum ether extract of Cissus quadrangularis (Linn) stimulates the growth of fetal bone during intra uterine developmental period: A morphometric analysis

Clinics

Volumn 63, Issue 6, 2008, Pages 815-820

  Potu, Bhagath Kumar ^a   Rao, Muddanna S ^a   Kutty N, G ^b   Bhat, Kumar M R ^a   Chamallamudi, Mallikarjuna Rao ^b   Nayak, Soubhagya Ranjan ^c  

^a KASTURBA MEDICAL COLLEGE   (India)

^b MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

^c KASTURBA MEDICAL COLLEGE   (India)

Author keywords

Alizarin red alcian blue; Estrogens; Ossification; Phytoestrogens

Indexed keywords

ALKANE; NAPHTHA; PLANT EXTRACT;

ANIMAL; ARTICLE; BONE DEVELOPMENT; CHEMISTRY; CISSUS; DRUG EFFECT; FEMALE; FETUS DEVELOPMENT; PREGNANCY; RANDOMIZATION; RAT; TOXICITY TESTING; WISTAR RAT;

ACUTE TOXICITY TESTS; ALKANES; ANIMALS; BONE DEVELOPMENT; CISSUS; FEMALE; FETAL DEVELOPMENT; PLANT EXTRACTS; PREGNANCY; RANDOM ALLOCATION; RATS; RATS, WISTAR;

EID: 57349153996     PISSN: 18075932     EISSN: None     Source Type: Journal    
DOI: 10.1590/S1807-59322008000600018     Document Type: Article

References (35)

1. Barker DJP. Mothers, babies and health in later life. 2nd ed. Churchill Livingstone: Edinburgh; 1998.
2. Day NL, Leech SL, Richardson GA, Cornelius MD, Robles N, Larkby C. Prenatal alcohol exposure predicts continued deficits in offspring size at 14 years of age. Alcohol Clin Exp Res. 2002;26:1584-91.
3. Deka DK, Lahon LC, Saikia J, Mukit A. Effect of Cissus quadrangularis in accelerating healing process of experimentally fractured radius-ulna of dog, a preliminary study. Indian J of Pharmacol. 1994;26:44-5.
4. Udupa KN, Prasad GC. Further studies on the effect of Cissus quadrangularis in accelerating fracture healing. Indian J Med Res. 1964;52:26-35.
5. Udupa KN, Prasad GC. Cissus quadrangularis in healing of fractures. A clinical study. J Indian Med Assoc. 1962; 38:590-593.
6. Chidambara Murthy KN, Vanitha A, Mahadeva Swamy M, Ravishankar GA. Antioxidant and antimicrobial activity of Cissus quadrangularis. L J Med Food. 2003; 6:99-105.
7. Singh SP, Mishra N, Dixit KS, Singh N, Kohli RP. An experimental study of analgesic activity of Cissus quadrangularis. Indian J of Pharmacol. 1984;79:162-63.
8. Oliver-Bever B. Medicinal plants in tropical West Africa. II. Plants acting on the nervous system. J Ethnopharmacol. 1983;7:1-93.
9. Jainu M, Devi CS. Gastroprotective action of Cissus quadrangularis extract against NSAID induced gastric ulcer: role of proinflammatory cytokines and oxidative damage. Chem Biol Interact. 2006;161:262-70.
10. Jainu M, Mohan KV, Devi CS. Protective effect of Cissus quadrangularis on neutrophil mediated tissue injury induced by aspirin in rats. J Ethnopharmacol. 2006; 104:302-5.
11. Oben JE, Ngondi JL, Momo CN, Agbor GA, Sobgui CS. The use of a Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study. Lipids Health Dis. 2008;7:12.
12. Singh G, Rawat P, Maurya R. Constituents of Cissus quadrangularis. Nat Prod Res. 2007;21:522-8.
13. Panthong A, Supraditaporn W, Kanjanapothi D, Taesotikul T, Reutrakul V. Analgesic, anti-inflammatory and venotonic effects of Cissus quadrangularis Linn. J Ethnopharmacol. 2007;110:264-70.
14. Jain A, Dixit J, Prakash D. Modulatory effects of Cissus quadrangularis on periodontal regeneration by bovine-derived hydroxyapatite in intrabony defects: exploratory clinical trial. J Int Acad Periodontol. 2008;10:59-65.
15. Sen SP. Study of the active constituents (ketosteroids) of Cissus quadrangularis. Indian J of Pharmacol. 1964;4:247.
16. Mehta M, Kaur N, Bhutani KK. Determination of marker constituents from Cissus quadrangularis Linn. and their quantitation by HPTLC and HPLC. Phytochem Anal. 2001;12:91-5.
17. Shirwaikar A, Khan S, Malini S. Antiosteoporotic effect of ethanol extract of Cissus quadrangularis Linn. on ovariectomized rat. J Ethnopharmacol. 2003; 89:245-50.
18. Potu BK, Rao MS, Swamy NVB, Kutty GN. Cissus quadrangularis plant extract enhances the ossification of fetal bones. Pharmacologyonline. 2007;1:63-70.
19. Rao MS, Potu BK, Swamy NVB, Kutty GN. Cissus quadrangularis plant extractenhances the development of cortical bone and trabeculae in the fetal femur. Pharmacologyonline. 2007;3:190-202.
20. Adlercreutz H, Mazur W: Phytoestrogens and Western diseases. Ann. Med. 1997;29:95-120.
21. Adlercreutz H: Phytooestrogens and cancer. Lancet Oncol. 2002;3:364-73.
22. Greenman DI, Delongchamp RR. Interactive response to DES in CH3 mice. Food Chem Toxicol. 1986;24:931-34.
23. Eriksen EF, Colvard DS, Berg NJ, Graham ML, Mann KG, Spelberg TC, et al. Evidence of estrogen receptor in normal human osteoblast like cells. Science. 1988;241:84-6.
24. Gray TK, Flynn TC, Gray KM, Nabell LM. 17βestrodiol acts directly on the clonal osteoblastic cell line UMR-106. PNAS. 1987;84:6267-71.
25. Ernst M Parker MG, Rodan GA. Functional estrogen receptor in osteoblastic cellsdemonstrated by transfection with a receptor gene containing an estrogen responseelement. Mol Endocrinol. 1991;5:1597-06.
26. Migliaccio S, Davis VL, Gibson MK, Gray KT, Korach KS. Estrogens modulate theresponsiveness of osteoblast like cells (ROS 17/2. 8) stably transfected with estrogen receptor. Endocrinology. 1992;130:2617-24.
27. Ghosh. MN. Fundamentals of Experimental Pharmacology, 2nd Ed, Calcutta, India: Scientific Book Agency. 1984; pp. 153-57.
28. Minoru I. Differential staining of cartilage and bone in fetal mouse skeleton by alcian blue and alizarin red s. Cong. Anom. 1976;16:171-73.
29. Todaka E, Sakurai K, Fukata H, Miyagawa H, Uzuki M, Omori M, et al. Fetal exposure to phytoestrogens - the difference in phytoestrogens status between mother and fetus. Environ. Res. 2005;99:195-203.
30. Mustafa AM, Malintan NT, Seelan S, Zhan Z, Mohamed Z, Hassan J, et. al. Phytoestrogens levels determination in the cord blood from Malaysia rural and urban populations. Toxicol and Appl Pharmacol. 2007;222:25-32.
31. Migliaccio S, Newbold RR, Bullock BC, Jefferson WJ, Sutton FG JR, Mclachlan JA, et. al. Alterations of maternal estrogen levels during gestation affect the skeleton of female offspring. Endocrinology. 1996;137:2118-25.
32. Chagin AS, Chrysis D, Takigawa M, Ritzen EM, Savendahl L. Locally produced estrogen promotes fetal rat metatarsal bone growth; an effect mediated through increased chondrocytes proliferation and decreased apoptosis. Journal of Endocrinology. 2006; 188: 193-203.
33. Cooper C, Javaid MK, Taylor P, Walker Bone K, Dennison E, Arden N. Fetal origin of osteoporotic fractures. Calcif Tissue Int. 2002;70:391-94.
34. Lindsay R, Hart DM, Aikken JM, McDonald EB, Anderson JB, Clark AC. Long-term prevention of postmenopausal osteoporosis by estrogen: evidence of an increased bone mass after delayed onset of estrogen treatment. Lancet. 1976;1:1038-40.
35. Wronsky TJ, Cintron M, Doherty AL, Dann LM. Estrogen treatment prevents osteopenia and depresses bone turnover in ovariectomized rats. Endocrinology. 1988; 123:681-86.