Alterations of maternal estrogen levels during gestation affect the skeleton of female offspring

Endocrinology

Volumn 137, Issue 5, 1996, Pages 2118-2125

  Migliaccio, Silvia ^a,b   Newbold, Retha R ^a   Bullock, Bill C ^c   Jefferson, Wendy J ^a   Sutton Jr , Frank G ^a   Mclachlan, John A ^d   Korach, Kenneth S ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

^d TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIETHYLSTILBESTROL; ESTROGEN; ESTROGEN RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM METABOLISM; CELL ACTIVITY; ESTROGEN BLOOD LEVEL; ESTROGEN RELEASE; FEMALE; FETUS; MENOPAUSE; MOUSE; NONHUMAN; OSSIFICATION; OSTEOPOROSIS; PREGNANCY; PRIORITY JOURNAL;

EID: 0029863107     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.5.8612556     Document Type: Article

References (56)

1. Beato M 1989 Gene regulation by steroid hormones. Cell 56:335-344
2. Evans RM 1988 The steroid and thyroid hormone receptor superfamily. Science 240:889-895
3. Carson-Jurica MA, Schrader WT, O'Malley BW 1990 Steroid receptor family: structure and functions. Enciocr Rev 11:201-220
4. Korach KS 1979 Estrogen action in the mouse uterus: characterization of the cytosol and nuclear receptor system. Endocrinology 104: 1324-1332
5. Gorski J, Toft D, Shymala G, Smith D, Notides A 1968 Recent Prog Horm Res 24:45-50
6. Quarmby V, Korach KS 1984 The influence of 17 beta estradiol on patterns of cell division in the u torus. Endocrinology 114:694-702
7. Herbst AL 1981 Developmental effects of diethylstilbestrol (DES) in pregnancy Herbst AL, Bern HA (eds) Thieme-Stratton Inc., New York, 318-320
8. McLachlan JA, Newbold BC, Bullock BC 1980 Long-term effects on the female mouse genital tract associated with the prenatal exposure to diethylstilbestrol. Cancer Res 40:3988-3999
9. Newbold RR, Bullock BC, McLachlan JA 1990 Uterine adenocarcinoma in mice following developmental treatment with estrogens: a model for hormonal carcinogenesis. Cancer Res 50:7677-7681
10. Herbst AL, Poskanzer DC, Robboy SJ, Friedlander L, Scully RE 1975 Prenatal exposure to stilbestrol. A prospective comparison of exposed female offspring with unexposed controls. N Engl J Med 292:334-339
11. Iguchi T, Ostrander PL, Mills KT, Bern HA 1985 Induction of abnormal epithelium changes by estrogen in neonatal mouse vaginal transplants. Cancer Res 45:5688-5693
12. Takasugi N, Bern HA 1964 Tissue changes in mice with persistent vaginal cornification induced by early postnatal treatment with estrogn. J Natl Cancer Inst 33:855-865
13. Herbst AL, Ulfeder H, Poskanzer DC 1971 Adenocarcinoma of the vagina. Association of maternal stilbestrol therapy with tumor appearance in young women. N Engl J Med 284:878-881
14. Gray TK, Flynn TC, Gray KM, Nabell LM 1987 17-β-Estradiol acts directly on the clonal osteoblastic cell line UMR-106. Proc Natl Acad Sci USA 84:6267-6271
15. Albright F, Bloomberg F, Smith PH 1940 Postmenopausal osteoporosis. Trans Assoc Am Physicians 55:298-305
16. Lindsay R, Hart DM, Aikken JM, McDonald EB, Anderson JB, Clark AC 1976 Long-term prevention of post-menopausal osteoporosis by estrogen: evidence of an increased bone mass after delayed onset of estrogen treatment. Lancet 1:1038-1040
17. Wronsky TJ, Cintron M, Doherty AI Dann LM 1988 Estrogen treatment prevents osteopenia and depresses bone turnover in ovariectomized rats. Endocrinology 123:681-686
18. Yamamoto TT, Rodan GA 1991 Direct effects of 17 beta estradiol on trabecular bone in ovariectomized rats. Proc Natl Acad Sci USA 87:2172-2176
19. Greenman DI Delongchamp RR 1986 Interactive responses to DES in CH3 mice. Food Chem Toxicol 24:931-934
20. Highman B, Roth SI, Greenman DL 1981 Osseus changes and osteosarcomas in mice continuously fed diets containing DES or 17-β-estradiol. J Natl Cancer Inst 67:653-662
21. Balfour JA, McTavish 1992 Transdermal estradiol. A review of its pharmacological profile, and therapeutic potential in the prevention of postmenopausal osteoporosis. Drugs Aging 2:487-507
22. Komm BS, Terpening CM, Benz DJ, Graeme KA, Gallegos A, Kore M, Greene GL, O'Malley BW, Haussler MR 1988 Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells. Science 241:81-84
23. Eriksen EF, Colvard DS, Berg NJ, Graham ML, Mann KG, Spelsberg TC, Riggs BL 1988 Evidence of estrogen receptors in normal human osteoblast-like cells. Science 241:84-86
24. Ernst M, Parker MG, Rodan GA 1991 Functional estrogen receptor in osteoblastic cells demonstrated by transfection with a reporter gene containing an estrogen response element. Mol Endocrinol 5:1597-1606
25. Migliaccio S, Davis VL, Gibson MK, Gray KT, Korach KS 1992 Estrogens modulate the responsiveness of osteoblast-like cells (ROS 17/2.8) stably transfected with estrogen receptor. Endocrinology 130:2617-2624
26. Rosenfield RL 1991 Puberty and its disorders in girls. Endocrinol Metab Clin North Am 20:15-42
27. Ross JL, Long LM, Skerda M, Cassorla F, Kurtz D, Loriaux DL, Cutler GB Jr 1986 Effects of low doses of estradiol on 6-months growth rate and predicted height in patients with Turner syndrome. J Pediatr 109:950-953
28. Turner RT, Vandersteenhoven JJ, Bell NH 1987 The effects of ovariectomy and 17-β Estradiol on cortical bone hystomorphometry in growing rats. J Bone Miner Res 2:115-122
29. Migliaccio S, Newbold RR, Bullock BC, McLachlan JA, Korach KS 1992 Developmental exposure to estrogens induces persistent changes in skeletal tissue. Endocrinology 130:1756-1758
30. Yasuo U, Taguchi O, Noumura T, Iguchi T 1992 Effects of sex steroids on the development of sexual dimorphism in mouse innominte bone. Anat Rec 234:541-548
31. Peng TC, Garner SC, Hirsch PF, Posillico JT 1986 Cytochemical bioassay of circulating concentration of rat parathyroid hormone: application to a study of age and sex. J Bone Miner Res 1:351-357
32. Cox AC, Balloun SL 1971 Prediction of total skeleton mineralization from individual bone data. Poultry Sci 50:186-194
33. Schwartz Z, Soskkolne WA, Neubauer T, Goldstein M, Adi S, Ornoy A 1991 Direct and sex specific enhancement of bone formation and calcification by sex steroids in fetal mice long bone in vitro (biochemical and morphometric study). Endocrinology 129:1167-1174
34. Edwards MW, Bain SD, Bailey MC, Lantry MM, Howard GA 1992 17-β- estradiol stimulation of endosteal bone formation in the ovariectomized mouse: an animal model for the evaluation of bone targeted estrogens. Bone 13:29-34
35. Simmons DJ 1966 Collagen formation and endochondral ossification in estrogen treated mice. PSEBM 121:1165-1168
36. Ostadalova I 1976 The effect of single dose of oestrogens administered during the early postnatal period on the DNA content of rat bone epiphyses. Physiol Bohemosl 25:97-102
37. Corvol MT, Carrascosa A, Tsagris L, Blanchard D, Rappaport R 1987 Evidence for a direct in vitro action of sex steroids on rabbit cartilage cells during skeletal growth: influence of age and sex. Endocrinology 120:1422-1429
38. Dayani N, Paul MI, Robel P, Eychenne B, Moncharmont B, Tasgris L, Rappaport R 1988 Estrogen receptor in cultured rabbit articular chondrocytes. Influence of age. J Steroid Biochem 31:351-356
39. Wronsky TJ, Cintron M, Doherty AI Dann LM 1988 Estrogen treat-ment prevents osteopenia and depresses bone turnover in ovariectomized rats. Endocrinology 123:681-686
40. Turner RT, Riggs LB, Spelsberg TC 1994 Skeletal effects of estrogen. Endocr Rev 15:275-300
41. Chow J, Tobias JH, Colston KW, Chambers TJ 1992 Estrogen maintains trabecular bone volume in rats not only by suppression of bone resoption but also by stimulation of bone formation. J Clin Invest 89:74-78
42. Takeuchi M, Tokin M, Nagata K 1995 Tamoxifen directly stimulates the mineralization of human osteoblast-like osteosarcoma cells through a pathway independent of estrogen response element. Biochem Biophys Res Commun 210:295-301
43. Smith EP, Boyd J, Frank GR, Takahashi H, Cohen RM, Specker B, Williams TC, Lubahn DB, Korach KS 1994 Estrogen resistance caused by a mutation in the estrogen receptor gene in a man. N Engl J Med 331:1056-1061
44. Raisz LG 1993 Local and systemic factors in the pathogenesis of osteoporosis. World Rev Nutr Diet 72:92-101
45. Raisz LG 1990 The role of prostaglandins in the local regulation of bone metabolism. Prog Clin Biol Res 332:195-203
46. Canalis E 1993 Insulin like growth factors and the local regulation of bone formation. Bone 14:273-276
47. Finkelman RD 1992 Growth factors in bones and teeth. J Calif Dent Assoc 20:23-29
48. Chalbos D, Philips A, Rochefort H 1994 Genomic cross-talk between the estrogen receptor and growth factor regulatory pathways in estrogen target tissues. Semin Cancer Biol 5:361-368
49. Migliaccio S, Wetsel WC, Fox WM, Washburn TF, Korach KS 1993 Endogenous protein kinase C activation in osteoblast-like cells modulates responsiveness to estrogen and estrogen receptor levels. Mol Endocrinol 7:1133-1143
50. Ignar-Trowbridge DM, Nelson KG, Bidwell MC, Curtis SW, Washburn TF, McLachlan JA, Korach KS 1992 Coupling of dual signal signaling pathways: Epidermal growth factor action involves the estrogen receptor. Proc Natl Acad Sci USA 89:4658-4662
51. Raisz LG 1994 Assessment of the risk of osteoporosis at the menopause: therapeutic consequences. Osteoporosis Int. 4:53-57
52. Kelly PJ, Twomey L, Sambrook PN, Eisman JA 1990 Sex differences in peak adult bone mineral density. J Bone Miner Res 5:1169-1175
53. Johnston Jr CC, Miller JZ, Slemenda CW, Reister TK, Hui S, Christian JC, Peacock M 1992 Calcium supplementation and increases in bone density in children. New Engl J Med 327:82-87
54. Weinberg J, D'Alquen G, Bezio S 1990 Interactive effects of ethanol intake and maternal nutritional status on skeletal development of fetal rats. Alcohol 7:383-388
55. Lee M, Leichter J 1983 Skeletal development in fetuses of rats consuming alcohol during gestation. Growth 47:254-262
56. Balansky RM, Blagoeva PM 1989 Tobacco smoke-induced clastogenicity in mouse fetuses and in newborn mice. Mutat Res 223:1-6