Alteration of skin hydration and its barrier function by vehicle and permeation enhancers: A study using TGA, FTIR, TEWL and drug permeation as markers

Methods and Findings in Experimental and Clinical Pharmacology

Volumn 30, Issue 7, 2008, Pages 499-512

  Shah, D K ^a   Khandavilli, S ^a   Panchagnula, R ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Gravimetric analysis; Imipramine; Infrared spectroscopy; Permeation enhancers; Skin hydration; Transepidermal water loss

Indexed keywords

ALCOHOL; IMIPRAMINE; LIPID; PROPYLENE GLYCOL;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEHYDRATION; DRUG PENETRATION; HYDRATION; INFRARED SPECTROSCOPY; LIPID BILAYER; NONHUMAN; PERMEABILITY BARRIER; PROTEIN DOMAIN; RAT; SKIN PENETRATION; SKIN WATER LOSS; STRATUM CORNEUM; THERMOGRAVIMETRY; WATER CONTENT;

ADMINISTRATION, CUTANEOUS; ADRENERGIC UPTAKE INHIBITORS; AMIDES; ANIMALS; EPIDERMIS; EPITHELIAL CELLS; IMIPRAMINE; LIPIDS; PERMEABILITY; PROPYLENE GLYCOL; RATS; RATS, SPRAGUE-DAWLEY; SKIN; SKIN ABSORPTION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SPECTROSCOPY, NEAR-INFRARED; THERMOGRAVIMETRY; VEHICLES; WATER; WATER LOSS, INSENSIBLE;

EID: 57349107203     PISSN: 03790355     EISSN: None     Source Type: Journal    
DOI: 10.1358/mf.2008.30.7.1159653     Document Type: Article

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