Effect of fatty acids on the permeation of melatonin across rat and pig skin in-vitro and on the transepidermal water loss in rats in-vivo

Journal of Pharmacy and Pharmacology

Volumn 51, Issue 7, 1999, Pages 783-790

  Kandimalla, K ^a   Kanikkannan, N ^a   Andega, S ^a   Singh, M ^a  

^a FLORIDA A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LAURIC ACID; LINOLENIC ACID; MELATONIN; MYRISTIC ACID; NONANOIC ACID; OLEIC ACID; SATURATED FATTY ACID; UNDECANOIC ACID; UNSATURATED FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG PENETRATION; MALE; NONHUMAN; RAT; SKIN PERMEABILITY; SKIN WATER LOSS; SWINE; TRANSDERMAL DRUG ADMINISTRATION;

EID: 0032773028     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357991773140     Document Type: Article

References (30)

1. Aungst, B. J. (1989) Structure/effect studies of fatty acid isomers as skin penetration enhancers and skin irritants. Pharm. Res. 6: 244-247
2. Aungst, B. J., Rogers, N. J., Shefter, E. (1986) Enhancement of naloxone penetration through human skin in-vitro using fatty acids, fatty alcohols, surfactants, sulfoxides and amides. Int. J. Pharm. 33: 225-234
3. Aungst, B. J., Blake, J. A., Rogers, N. J., Hussain, M. A. (1990) Transdermal oxymorphone formulation development and methods for evaluating flux and lag times for two skin permeation-enhancing vehicles. J. Pharm. Sci. 79: 1072-1076
4. Barry, B. W. (1987) Mode of action of penetration enhancers in human skin. J. Contr. Rel. 6: 85-97
5. Benes, L., Claustrat, B., Honiere, F., Geoffriau, M., Konsil, J., Parrott, K. A., Degrande G., McQuinn, R. L., Ayres, J. W. (1997) Transmucosal, oral controlled-release, and transdermal drug administration in human subjects: a crossover study with melatonin. J. Pharm. Sci. 86: 1115-1119
6. Bond, J. R., Barry, B. W. (1988) Hairless mouse skin is limited as a model for assessing the effects of penetration enhancers in human skin. J. Invest. Dermatol. 90: 810-813
7. Brain, K. R., Walters, K. A. (1993) Molecular modeling of skin permeation enhancement by chemical agents. In: Walter, K. A., Hadgraft, J. (eds) Pharmaceutical Skin Penetration Enhancement. Marcel Dekker, Inc, New York, pp 389-416
8. Bronaugh, R. L., Stewart, R. F., Congdon, E. R. (1982) Methods for in-vitro percutaneous absorption studies. II. Animal models for human skin. Toxicol. Appl. Pharmacol. 62: 481-488
9. Carelli, V., Di Colo, G., Nannipieri, E., Serafini, M. F. (1992) Enhancement effects in the permeation of alprazolam through hairless mouse skin. Int. J. Pharm. 88: 89-97
10. Dyer, A., Aziza, M. A. E. (1989) Skin permeability to aromatic carboxylic acids: an in-vitro comparison in pig ear, white mouse and brown mouse. Int. J. Cosmet. Sci. 11: 175-183
11. Gao, S., Singh, J. (1997) Mechanism of transdermal transport of 5-fluorouracil by terpenes: carvone, 1,8-cineole and thymol. Int. J. Pharm. 154: 67-77
12. Golden, G. M., Guzek, D. B., Harris, R. R., McKie, J. E., Potts, R. O. (1986) Lipid thermotropic transitions in human stratum corneum. J. Invest. Dermatol. 86: 255-259
13. Konsil, J., Parrott, K. A., Ayres, J. W. (1995) Development of a transdermal delivery device for melatonin in-vitro study. Drug Dev. Ind. Pharm. 21: 1377-1387
14. Lee, B. J., Parrott, K. A., Ayres, J. W., Sack, R. L. (1994) Preliminary evaluation of transdermal delivery of melatonin in human subject. Res. Commun. Mol. Path. Pharmacol. 85: 337-346
15. Lee, B. J., Parrott, K. A., Ayres, J. W., Sack, R. L. (1996) Development and characterization of an oral of an controlled release delivery system for melatonin. Drug Dev. Ind. Pharm. 22: 269-274
16. Maibach, H. I., Bronaugh, R., Guy, R. H., Turr, E., Wilson, D., Jacques, S., Chaing, D. (1984) Non invasive techniques for determining skin function. In: Drill, V. A., Lazar, P. (eds) Cutaneous Toxicity. Raven Press, pp 63-97
17. Mallo, C., Zaidan, R., Galy, G., Vermeulen, E., Brun, J., Chazot, G., Claustrat, B. (1990) Pharmacokinetics of melatonin in man after intravenous infusion and bolus injection. Eur. J. Clin. Pharmacol. 38: 297-301
18. Michaels, A. S., Chandrasekaran, S. K., Shaw, J. E. (1975) Permeation through human skin: theory and in-vitro experimental measurement. Am. Inst. Chem. Eng. J. 21: 985-996
19. Monteiro-Riviere, N. A. (1986) Ultrastructural evaluation of porcine integument. In: Tumbleson, M. E. (ed.) Swine in Biomedical Research. Plenum Press, New York, pp 641-655
20. Morimoto, K., Tojima, H., Haruta, T., Suzuki, M., Kakemi, M. (1996) Enhancement effects of unsaturated fatty acids with various structures on the permeation of indomethacin through rat skin. J. Pharm. Pharmacol. 48: 1133-1137
21. Ogiso, T., Shintani, M. (1990) Mechanism for the enhancement effect of fatty acids on the percutaneous absorption of propranolol. J. Pharm. Sci. 79: 1065-1071
22. Okamoto, H., Ohyabu, M., Hashida, M., Sezaki, H. (1987) Enhanced penetration of mitomycin C through hairless mouse and rat skin by enhancers with terpene moieties. J. Pharm. Pharmacol. 39: 531-534
23. Ongpipattanakul, B., Burnette, R., Potts, R. O. (1991) Evidence that oleic acid exists as a separate phase within stratum corneum. Pharm. Res. 8: 350-354
24. Potts, R. O., Francoeur, M. L. (1990) Lipid biophysics of water loss through the skin. Proc. Natl Acad. Sci. USA 87:3871-3873
25. Priborsky, J., Muhlbachova, E. (1990) Evaluation of in vitro percutaneous absorption across human skin and in animal models. J. Pharm. Pharmacol. 42: 468-472
26. Tanojo, H., Bouwstra, J. A., Junginger, H. E., Bodde, H. A. (1997a) In-vitro human skin barrier modulation by fatty acids: skin permeation and thermal analysis studies. Pharm. Res. 14: 42-49
27. Tanojo, H., Junginger, H. E., Bodde, H. A. (1997b) In-vivo human skin permeability enhancement by oleic acid: transepidermal water loss and Fourier-transform infrared spectro-scopy studies. J. Contr. Rel. 47: 31-39
28. Tanojo, H., Boelsma, E., Junginger, H. E., Ponec, M., Bodde, H. A. (1998) In-vivo human skin barrier modulation by topical application of fatty acids. Skin Pharmacol. Appl. Skin Physiol. 11: 87-97
29. Wester, R. C., Maibach, H. I. (1987) Animal models for transdermal delivery. In: Kydoneus, A. F., Berner, B. (eds) Transdermal Delivery of Drugs. Vol. I, CRC Press Inc., Boca Raton, FL, USA, pp 61-70
30. Yosipovitch, G., Szolar, C., Hui, X. Y., Maibach, H. (1996) Effect of topically applied Menthol on thermal, pain and itch sensations and biophysical properties of the skin. Arch. Dermatol. Res. 288: 245-248