Validation of the rat limb bud micromass test in the international ECVAM validation study on three in vitro embryotoxicity tests

Alternatives to Laboratory Animals

Volumn 32, Issue 3, 2004, Pages 245-274

  Spielmann, Horst ^a   Genschow, Elke ^a   Brown, Nigel A ^b   Piersma, Alder H ^c   Verhoef, Aart ^c   Spanjersberg, Marielle Q I ^c   Huuskonen, Hannele ^d   Paillard, Francoise ^e   Seiler, Andrea ^a  

^a FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

^b ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^c NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^e SANOFI   (France)

Author keywords

ECVAM; In vitro embryotoxicity test; In vitro toxicology; Micromass; Prediction model; Prevalidation; Rat embryo limb buds; Validation

Indexed keywords

6 AMINONICOTINAMIDE; ACRYLAMIDE; BORIC ACID; CYTARABINE; HYDROXYUREA; PHENYTOIN; PHTHALIC ACID DIMETHYL ESTER; RETINOIC ACID; SACCHARIN SODIUM; SALICYLIC ACID DERIVATIVE; SALICYLIC ACID SODIUM SALT; TOXIC SUBSTANCE; UNCLASSIFIED DRUG;

ANIMAL CELL; CHEMICAL ANALYSIS; CONFERENCE PAPER; EMBRYO; EMBRYO CELL; EMBRYOTOXICITY; EVALUATION; IN VITRO STUDY; LABORATORY; LIMB BUD; MESENCEPHALON; MICROMASS TEST; MODEL; NONHUMAN; PERFORMANCE; PREDICTION; PRIORITY JOURNAL; RAT; STANDARD; TOXICITY TESTING; VALIDATION PROCESS;

ANIMALIA;

EID: 8744315357     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290403200306     Document Type: Conference Paper

References (23)

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