Increased SOCS expression in peripheral blood mononuclear cells of end stage renal disease patients is related to inflammation and dialysis modality

European Journal of Pharmacology

Volumn 602, Issue 1, 2009, Pages 163-167

  Rastmanesh, M Mehdi ^a   Braam, Branko ^a,b   Joles, Jaap A ^a   Boer, Peter ^a   Bluyssen, Hans A R ^c  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY OF ALBERTA   (Canada)

^c INSTITUTE OF MOLECULAR PHYSICS   (Poland)

Author keywords

End stage renal disease; Inflammation; Peripheral blood mononuclear cells; SOCS

Indexed keywords

C REACTIVE PROTEIN; CYTOKINE; CYTOKINE INDUCIBLE SH2 CONTAINING PROTEIN 1; INTERLEUKIN 6; SUPPRESSOR OF CYTOKINE SIGNALING; SUPPRESSOR OF CYTOKINE SIGNALING 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEMODIALYSIS; HUMAN; HUMAN CELL; INFLAMMATION; KIDNEY FAILURE; LYMPHOCYTE; MALE; MONOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PERITONEAL DIALYSIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION;

C-REACTIVE PROTEIN; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; INTERLEUKIN-6; KIDNEY FAILURE, CHRONIC; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; PERITONEAL DIALYSIS; RENAL DIALYSIS; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 57249104700     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.11.014     Document Type: Article

References (37)

1. Attia D.M., Ni Z.N., Boer P., Attia M.A., Goldschmeding R., Koomans H.A., Vaziri N.D., and Joles J.A. Proteinuria is preceded by decreased nitric oxide synthesis and prevented by a NO donor in cholesterol-fed rats. Kidney Int. 61 (2002) 1776-1787
2. Brauner A., Lu Y., Hallden G., Hylander B., and Lundahl J. Difference in the blood monocyte phenotype between uremic patients and healthy controls: its relation to monocyte differentiation into macrophages in the peritoneal cavity. Inflammation 22 (1998) 55-66
3. Carlos T., Kovach N., Schwartz B., Rosa M., Newman B., Wayner E., Benjamin C., Osborn L., Lobb R., and Harlan J. Human monocytes bind to two cytokine-induced adhesive ligands on cultured human endothelial cells: endothelial-leukocyte adhesion molecule-1 and vascular cell adhesion molecule-1. Blood 77 (1991) 2266-2271
4. Collins A.J., Li S., Gilbertson D.T., Liu J., Chen S.C., and Herzog C.A. Chronic kidney disease and cardiovascular disease in the Medicare population. Kidney Int. (2003) S24-S31 Suppl
5. Cooper A.C., Breen C.P., Vyas B., Ochola J., Kemeny D.M., and Macdougall I.C. Poor response to recombinant erythropoietin is associated with loss of T-lymphocyte CD28 expression and altered interleukin-10 production. Nephrol. Dial. Transplant. 18 (2003) 133-140
6. Dhondt A., Vanholder R., Van Biesen W., and Lameire N. The removal of uremic toxins. Kidney Int. Suppl. 76 (2000) S47-59
7. Egwuagu C.E., Yu C.R., Zhang M., Mahdi R.M., Kim S.J., and Gery I. Suppressors of cytokine signaling proteins are differentially expressed in Th1 and Th2 cells: implications for Th cell lineage commitment and maintenance. J. Immunol. 168 (2002) 3181-3187
8. Flo R.W., Naess A., Lund-Johansen F., Maehle B.O., Sjursen H., Lehmann V., and Solberg C.O. Negative selection of human monocytes using magnetic particles covered by anti-lymphocyte antibodies. J. Immunol. Methods 137 (1991) 89-94
9. Fujimoto M., Naka T., Nakagawa R., Kawazoe Y., Morita Y., Tateishi A., Okumura K., Narazaki M., and Kishimoto T. Defective thymocyte development and perturbed homeostasis of T cells in STAT-induced STAT inhibitor-1/suppressors of cytokine signaling-1 transgenic mice. J. Immunol. 165 (2000) 1799-1806
10. Fujimoto M., Tsutsui H., Xinshou O., Tokumoto M., Watanabe D., Shima Y., Yoshimoto T., Hirakata H., Kawase I., Nakanishi K., Kishimoto T., and Naka T. Inadequate induction of suppressor of cytokine signaling-1 causes systemic autoimmune diseases. Int. Immunol. 16 (2004) 303-314
11. Goicoechea M., Martin J., de Sequera P., Quiroga J.A., Ortiz A., Carreno V., and Caramelo C. Role of cytokines in the response to erythropoietin in hemodialysis patients. Kidney Int. 54 (1998) 1337-1343
12. Heine G.H., Ulrich C., Seibert E., Seiler S., Marell J., Reichart B., Krause M., Schlitt A., Kohler H., and Girndt M. CD14(++)CD16+ monocytes but not total monocyte numbers predict cardiovascular events in dialysis patients. Kidney Int. 73 (2008) 622-629
13. Huang K.C., Chen C.W., Chen J.C., and Lin W.W. Statins induce suppressor of cytokine signaling-3 in macrophages. FEBS Lett. 555 (2003) 385-389
14. Klinger J., Enriquez J., Arturo J.A., Delgado M., Avila G., and Ceballos O. Cytokines and peritonitis in continuous ambulatory peritoneal dialysis: immunodeviation and immunodeficiency. Adv. Perit. Dial. 18 (2002) 170-176
15. Krebs D.L., and Hilton D.J. SOCS: physiological suppressors of cytokine signaling. J. Cell Sci. 113 Pt 16 (2000) 2813-2819
16. Leon M.L., and Zuckerman S.H. Gamma interferon: a central mediator in atherosclerosis. Inflamm. Res. 54 (2005) 395-411
17. Li S., Chen S., Xu X., Sundstedt A., Paulsson K.M., Anderson P., Karlsson S., Sjogren H.O., and Wang P. Cytokine-induced Src homology 2 protein (CIS) promotes T cell receptor-mediated proliferation and prolongs survival of activated T cells. J. Exp. Med. 191 (2000) 985-994
18. Litjens N.H., van Druningen C.J., and Betjes M.G. Progressive loss of renal function is associated with activation and depletion of naive T lymphocytes. Clin. Immunol. 118 (2006) 83-91
19. Malaponte G., Bevelacqua V., Fatuzzo P., Rapisarda F., Emmanuele G., Travali S., and Mazzarino M.C. IL-1beta, TNF-alpha and IL-6 release from monocytes in haemodialysis patients in relation to dialytic age. Nephrol. Dial. Transplant. 17 (2002) 1964-1970
20. Martin-Malo A., Carracedo J., Ramirez R., Rodriguez-Benot A., Soriano S., Rodriguez M., and Aljama P. Effect of uremia and dialysis modality on mononuclear cell apoptosis. J. Am. Soc. Nephrol. 11 (2000) 936-942
21. Matsumoto A., Seki Y., Kubo M., Ohtsuka S., Suzuki A., Hayashi I., Tsuji K., Nakahata T., Okabe M., Yamada S., and Yoshimura A. Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice. Mol. Cell. Biol. 19 (1999) 6396-6407
22. Meier P., Dayer E., Blanc E., and Wauters J.P. Early T cell activation correlates with expression of apoptosis markers in patients with end-stage renal disease. J. Am. Soc. Nephrol. 13 (2002) 204-212
23. Menegatti E., Rossi D., Chiara M., Alpa M., Sena L.M., and Roccatello D. Cytokine release pathway in mononuclear cells stimulated in vitro by dialysis membranes. Am. J. Nephrol. 22 (2002) 509-514
24. Moser B., Roth G., Brunner M., Lilaj T., Deicher R., Wolner E., Kovarik J., Boltz-Nitulescu G., Vychytil A., and Ankersmit H.J. Aberrant T cell activation and heightened apoptotic turnover in end-stage renal failure patients: a comparative evaluation between non-dialysis, haemodialysis, and peritoneal dialysis. Biochem. Biophys. Res. Commun. 308 (2003) 581-585
25. Novak U., Marks D., Nicholson S.E., Hilton D., and Paradiso L. Differential ability of SOCS proteins to regulate IL-6 and CSF-1 induced macrophage differentiation. Growth Factors 16 (1999) 305-314
26. Rastmanesh M.M., Bluyssen H.A., Joles J.A., Boer P., Willekes N., and Braam B. Increased expression of SOCS3 in monocytes and SOCS1 in lymphocytes correlates with progressive loss of renal function and cardiovascular risk factors in chronic kidney disease. Eur. J. Pharmacol. 593 (2008) 99-104
27. Schumacher H.R., Garvin D.F., and Triplett D.A. Introduction to Laboratory Hematology and Hematopathology. first ed. (1984), Alan R. Liss. Inc., New York, NY 9-107
28. Shouda T., Yoshida T., Hanada T., Wakioka T., Oishi M., Miyoshi K., Komiya S., Kosai K., Hanakawa Y., Hashimoto K., Nagata K., and Yoshimura A. Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis. J. Clin. Invest. 108 (2001) 1781-1788
29. Tang J., Kozaki K., Farr A.G., Martin P.J., Lindahl P., Betsholtz C., and Raines E.W. The absence of platelet-derived growth factor-B in circulating cells promotes immune and inflammatory responses in atherosclerosis-prone ApoE-/- mice. Am J Pathol 167 (2005) 901-912
30. Tedgui A., and Mallat Z. Cytokines in atherosclerosis: pathogenic and regulatory pathways. Physiol. Rev. 86 (2006) 515-581
31. van der Putten K., Braam B., Jie K.E., and Gaillard C.A. Mechanisms of disease: erythropoietin resistance in patients with both heart and kidney failure. Nat. Clin. Pract. Nephrol. 4 (2008) 47-57
32. Walker R.J., Sutherland W.H., and De Jong S.A. Effect of changing from a cellulose acetate to a polysulphone dialysis membrane on protein oxidation and inflammation markers. Clin. Nephrol. 61 (2004) 198-206
33. Wanner C., Bahner U., Mattern R., Lang D., and Passlick-Deetjen J. Effect of dialysis flux and membrane material on dyslipidaemia and inflammation in haemodialysis patients. Nephrol. Dial. Transplant. 19 (2004) 2570-2575
34. Wesemann D.R., Dong Y., O'Keefe G.M., Nguyen V.T., and Benveniste E.N. Suppressor of cytokine signaling 1 inhibits cytokine induction of CD40 expression in macrophages. J. Immunol. 169 (2002) 2354-2360
35. Wong C.K., Szeto C.C., Chan M.H., Leung C.B., Li P.K., and Lam C.W. Elevation of pro-inflammatory cytokines, C-reactive protein and cardiac troponin T in chronic renal failure patients on dialysis. Immunol. Invest. 36 (2007) 47-57
36. Wong P.K., Egan P.J., Croker B.A., O'Donnell K., Sims N.A., Drake S., Kiu H., McManus E.J., Alexander W.S., Roberts A.W., and Wicks I.P. SOCS-3 negatively regulates innate and adaptive immune mechanisms in acute IL-1-dependent inflammatory arthritis. J. Clin. Invest. 116 (2006) 1571-1581
37. Yamamoto T.Y.H., Koga M., et al. Lacking the SOCS3 gene in macrophages prevents the development of atherosclerosis in ApoE deficient mice. Circ. J. 71 (2007) 170