메뉴 건너뛰기




Volumn 40, Issue 12, 2006, Pages 2164-2169

Emerging therapies in the treatment of Clostridium difficile-associated disease

Author keywords

Clostridium difficile; Intravenous immunoglobulin; Nitazoxanide; Rifaximin; Tinidazole; Tolevamer; Vaccine

Indexed keywords

ANTIBIOTIC AGENT; ANTIPARASITIC AGENT; ANTITOXIN; CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B; CLOSTRIDIUM TOXIN; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; MACROLIDE; METRONIDAZOLE; MONOCLONAL ANTIBODY; NITAZOXANIDE; OPT 80; POLYMER; RAFALAZIL; RAMOPLANIN; RIFAMPICIN; RIFAMPICIN DERIVATIVE; RIFAXIMIN; TIACUMICIN B; TINIDAZOLE; TOLEVAMER; TOXOID; VACCINE; VANCOMYCIN;

EID: 33845609225     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1H340     Document Type: Article
Times cited : (36)

References (40)
  • 1
    • 3142680740 scopus 로고    scopus 로고
    • Clostridium difficile-associated diarrhea in adults
    • Poutanen SM, Simor AE. Clostridium difficile-associated diarrhea in adults. CMAJ 2004;171:51-8.
    • (2004) CMAJ , vol.171 , pp. 51-58
    • Poutanen, S.M.1    Simor, A.E.2
  • 2
    • 33644696907 scopus 로고    scopus 로고
    • Clostridium difficile-associated disease: An emerging threat to patient safety
    • Owens RC. Clostridium difficile-associated disease: an emerging threat to patient safety. Pharmacotherapy 2006;26:299-311.
    • (2006) Pharmacotherapy , vol.26 , pp. 299-311
    • Owens, R.C.1
  • 3
    • 23944507069 scopus 로고    scopus 로고
    • Treatment of Clostridium difficile-associated disease: Old therapies and new strategies
    • Aslam S, Hamill R, Musher DM. Treatment of Clostridium difficile-associated disease: old therapies and new strategies. Lancet Infect Dis 2005;5:549-57.
    • (2005) Lancet Infect Dis , vol.5 , pp. 549-557
    • Aslam, S.1    Hamill, R.2    Musher, D.M.3
  • 4
    • 3142705643 scopus 로고    scopus 로고
    • Risk of Clostridium difficile diarrhea among hospital inpatients prescribed proton pump inhibitors: Cohort and case control studies
    • Dial S, Alrasadi K, Manoukian C, et al. Risk of Clostridium difficile diarrhea among hospital inpatients prescribed proton pump inhibitors: cohort and case control studies. CMAJ 2004;171:33-8.
    • (2004) CMAJ , vol.171 , pp. 33-38
    • Dial, S.1    Alrasadi, K.2    Manoukian, C.3
  • 5
    • 29144473282 scopus 로고    scopus 로고
    • Use of gastric acid-suppressive agents and the risk of community-acquired Clostridium difficile-associated disease
    • Dial S, Delaney J, Berkun AN, et al. Use of gastric acid-suppressive agents and the risk of community-acquired Clostridium difficile-associated disease. JAMA 2005;294:2989-95.
    • (2005) JAMA , vol.294 , pp. 2989-2995
    • Dial, S.1    Delaney, J.2    Berkun, A.N.3
  • 6
    • 33845660938 scopus 로고    scopus 로고
    • Severe infections caused by Clostridium difficile-a growing problem
    • O'Mara NB. Severe infections caused by Clostridium difficile-a growing problem. Pharmacist Letter 2006;22(1):220108.
    • (2006) Pharmacist Letter , vol.22 , Issue.1 , pp. 220108
    • O'Mara, N.B.1
  • 7
    • 0030969261 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and management of Clostridium difficile-associated diarrhea and colitis
    • Feteky R. Guidelines for the diagnosis and management of Clostridium difficile-associated diarrhea and colitis. Am J Gastroenterol 1997;92:739-50.
    • (1997) Am J Gastroenterol , vol.92 , pp. 739-750
    • Feteky, R.1
  • 8
    • 0036840870 scopus 로고    scopus 로고
    • Treatment of Clostridium difficile-associated diarrhea
    • DOI 10.1345/aph.1A160
    • Malnick SD, Zimhony O. Treatment of Clostridium difficile-associated diarrhea. Ann Pharmacother 2002;36:1767-75. DOI 10.1345/aph.1A160
    • (2002) Ann Pharmacother , vol.36 , pp. 1767-1775
    • Malnick, S.D.1    Zimhony, O.2
  • 9
    • 1442302900 scopus 로고    scopus 로고
    • Outbreak of Clostridium difficile infection in a long-term care facility: Association and gatifloxacin use
    • Gaynes R, Rimland D, Killum E, et al. Outbreak of Clostridium difficile infection in a long-term care facility: association and gatifloxacin use. Clin Infect Dis 2004;38:640-5.
    • (2004) Clin Infect Dis , vol.38 , pp. 640-645
    • Gaynes, R.1    Rimland, D.2    Killum, E.3
  • 10
    • 28844494086 scopus 로고    scopus 로고
    • An epidemic, toxin gene-variant strain of Clostridium difficile
    • McDonald LC, Killgore GE, Thompson A, et al. An epidemic, toxin gene-variant strain of Clostridium difficile. N Engl J Med 2005;353:2433-41.
    • (2005) N Engl J Med , vol.353 , pp. 2433-2441
    • McDonald, L.C.1    Killgore, G.E.2    Thompson, A.3
  • 11
    • 28844441314 scopus 로고    scopus 로고
    • A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality
    • Loo VG, Poirier L, Miller MA, et al. A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality. N Engl J Med 2005;353:2442-9.
    • (2005) N Engl J Med , vol.353 , pp. 2442-2449
    • Loo, V.G.1    Poirier, L.2    Miller, M.A.3
  • 12
    • 19344364596 scopus 로고    scopus 로고
    • Relatively poor outcome after treatment of Clostridium difficile colitis with metronidazole
    • Musher DM, Aslam S, Logan N, et al. Relatively poor outcome after treatment of Clostridium difficile colitis with metronidazole. Clin Infect Dis 2005;40:1586-90.
    • (2005) Clin Infect Dis , vol.40 , pp. 1586-1590
    • Musher, D.M.1    Aslam, S.2    Logan, N.3
  • 13
    • 0022382249 scopus 로고
    • Antibiotic-associated colitis due to Clostridium difficile: Double-blind comparison of vancomycin with bacitracin
    • Young GP, Ward PB, Bayley N, et al. Antibiotic-associated colitis due to Clostridium difficile: double-blind comparison of vancomycin with bacitracin. Gastroenterology 1985;89:1038-45.
    • (1985) Gastroenterology , vol.89 , pp. 1038-1045
    • Young, G.P.1    Ward, P.B.2    Bayley, N.3
  • 14
    • 17844402953 scopus 로고    scopus 로고
    • Rifaximin: A nonabsorbable rifamycin antibiotic for use in nonsystemic gastrointestinal infections
    • Gerard L, Garey KW, Dupont HL. Rifaximin: a nonabsorbable rifamycin antibiotic for use in nonsystemic gastrointestinal infections. Expert Rev Anti Infect Ther 2005;3:201-11.
    • (2005) Expert Rev Anti Infect Ther , vol.3 , pp. 201-211
    • Gerard, L.1    Garey, K.W.2    Dupont, H.L.3
  • 15
    • 18644381269 scopus 로고    scopus 로고
    • Rifaximin, a poorly absorbed antibiotic: Pharmacology and clinical potential
    • Scarpignato C, Pelosini I. Rifaximin, a poorly absorbed antibiotic: pharmacology and clinical potential. Chemotherapy 2005;51(suppl 1):36-66.
    • (2005) Chemotherapy , vol.51 , Issue.SUPPL. 1 , pp. 36-66
    • Scarpignato, C.1    Pelosini, I.2
  • 16
    • 0007714298 scopus 로고
    • Treatment for colitis caused by Clostridium difficile: Results of a randomized, open-label study of rifaximin vs vancomycin
    • Boero M, Berti E, Morgando A, et al. Treatment for colitis caused by Clostridium difficile: results of a randomized, open-label study of rifaximin vs vancomycin. Microbiol Medica 1990;5:74-7.
    • (1990) Microbiol Medica , vol.5 , pp. 74-77
    • Boero, M.1    Berti, E.2    Morgando, A.3
  • 17
    • 16844372587 scopus 로고    scopus 로고
    • Nitazoxanide: A new thiazolide antiparasitic agent
    • Fox LM, Saravolatz LD. Nitazoxanide: a new thiazolide antiparasitic agent. Clin Infect Dis 2005;40:1173-80.
    • (2005) Clin Infect Dis , vol.40 , pp. 1173-1180
    • Fox, L.M.1    Saravolatz, L.D.2
  • 18
    • 0033836004 scopus 로고    scopus 로고
    • In vitro and in vivo activities of nitazoxanide agents against Clostridium difficile
    • McVay CS, Rolfe RD. In vitro and in vivo activities of nitazoxanide agents against Clostridium difficile. Antimicrob Agents Chemother 2000;44:2254-8.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 2254-2258
    • McVay, C.S.1    Rolfe, R.D.2
  • 19
    • 0029836681 scopus 로고    scopus 로고
    • In vitro evaluation of activities of nitazoxanide and tizoxanide against anaerobes and aerobic organisms
    • Dubreuil L, Houcke I, Mouton Y, et al. In vitro evaluation of activities of nitazoxanide and tizoxanide against anaerobes and aerobic organisms. Antimicrob Agents Chemother 1996;40:2266-70.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 2266-2270
    • Dubreuil, L.1    Houcke, I.2    Mouton, Y.3
  • 20
    • 33845638030 scopus 로고    scopus 로고
    • The emerging problem of metronidazole failure in Clostridium difficile colitis (CDC) and the response to treatment with nitazoxanide (NTX)
    • (abstract 319). Presented at, San Francisco, October 6-9
    • Melgarejo NA, Musher DM, Logan N, et al. The emerging problem of metronidazole failure in Clostridium difficile colitis (CDC) and the response to treatment with nitazoxanide (NTX) (abstract 319). Presented at: 43rd Meeting of Infectious Diseases Society of America, San Francisco, October 6-9, 2005.
    • (2005) 43rd Meeting of Infectious Diseases Society of America
    • Melgarejo, N.A.1    Musher, D.M.2    Logan, N.3
  • 21
    • 33746626011 scopus 로고    scopus 로고
    • Nitazoxanide for the treatment of Clostridium difficile colitis
    • Musher DM, Logan N, Hamill RJ, et al. Nitazoxanide for the treatment of Clostridium difficile colitis. Clin Infect Dis 2006;43:421-7.
    • (2006) Clin Infect Dis , vol.43 , pp. 421-427
    • Musher, D.M.1    Logan, N.2    Hamill, R.J.3
  • 22
    • 0025727765 scopus 로고
    • Treatment with intravenously administered gamma globulin of chronic relapsing colitis induced by Clostridium difficile toxin
    • Leung DY, Kelly CP, Boguniewicz, Pothoulakis C, LaMont JT, Flores A. Treatment with intravenously administered gamma globulin of chronic relapsing colitis induced by Clostridium difficile toxin. J Pediatr 1991;118:633-7.
    • (1991) J Pediatr , vol.118 , pp. 633-637
    • Leung, D.Y.1    Kelly, C.P.2    Boguniewicz3    Pothoulakis, C.4    LaMont, J.T.5    Flores, A.6
  • 23
    • 2442705389 scopus 로고    scopus 로고
    • Descriptive study of intravenous immunoglobulin for the treatment of recurrent Clostridium difficile diarrhoea
    • Wilcox MH. Descriptive study of intravenous immunoglobulin for the treatment of recurrent Clostridium difficile diarrhoea. J Antimicrob Chemother 2004;53:882-4.
    • (2004) J Antimicrob Chemother , vol.53 , pp. 882-884
    • Wilcox, M.H.1
  • 24
    • 33646582618 scopus 로고    scopus 로고
    • Intravenous immunoglobulin for the treatment of severe, refractory, and recurrent Clostridium difficile diarrhea
    • McPherson S, Rees CJ, Ellis R, et al. Intravenous immunoglobulin for the treatment of severe, refractory, and recurrent Clostridium difficile diarrhea. Dis Colon Rectum 2006;49:1-6.
    • (2006) Dis Colon Rectum , vol.49 , pp. 1-6
    • McPherson, S.1    Rees, C.J.2    Ellis, R.3
  • 25
    • 31144469850 scopus 로고    scopus 로고
    • Intravenous immunoglobulin for resistant Clostridium difficile infection
    • Murphy C, Vernon M, Cullen M. Intravenous immunoglobulin for resistant Clostridium difficile infection. Age Ageing 2006;35:85-6.
    • (2006) Age Ageing , vol.35 , pp. 85-86
    • Murphy, C.1    Vernon, M.2    Cullen, M.3
  • 26
    • 33750507063 scopus 로고    scopus 로고
    • Montvale, NJ: Thomson PDR
    • Drug topics red book. Montvale, NJ: Thomson PDR, 2006.
    • (2006) Drug Topics Red Book
  • 27
    • 33644516605 scopus 로고    scopus 로고
    • Tinidazole: A nitroimidazole antiprotozoal agent
    • Fung HB, Doan T. Tinidazole: a nitroimidazole antiprotozoal agent. Clin Ther 2005;27:1859-84.
    • (2005) Clin Ther , vol.27 , pp. 1859-1884
    • Fung, H.B.1    Doan, T.2
  • 28
    • 0023127929 scopus 로고
    • Comparative activity of metronidazole and tinidazole against Clostridium difficile and Peptostreptococcus anaerobius
    • Jokipii AN, Jokipii L. Comparative activity of metronidazole and tinidazole against Clostridium difficile and Peptostreptococcus anaerobius. Antimicrob Agents Chemother 1987;31:183-6.
    • (1987) Antimicrob Agents Chemother , vol.31 , pp. 183-186
    • Jokipii, A.N.1    Jokipii, L.2
  • 29
    • 33746656237 scopus 로고    scopus 로고
    • Tolevamer, a novel nonantibiotic polymer compared with vancomycin in the treatment of mild to moderately severe Clostridium difficile-associated diarrhea
    • Louie TJ, Peppe J, Watt K, et al. Tolevamer, a novel nonantibiotic polymer compared with vancomycin in the treatment of mild to moderately severe Clostridium difficile-associated diarrhea. Clin Infect Dis 2006;43:411-20.
    • (2006) Clin Infect Dis , vol.43 , pp. 411-420
    • Louie, T.J.1    Peppe, J.2    Watt, K.3
  • 30
    • 3042855154 scopus 로고    scopus 로고
    • Toxin binding of tolevamer, a polyanionic drug that protects against antibiotic-associated diarrhea
    • Braunlin W, Xu Q, Hook P, et al. Toxin binding of tolevamer, a polyanionic drug that protects against antibiotic-associated diarrhea. Biophysical J 2004;87:534-9.
    • (2004) Biophysical J , vol.87 , pp. 534-539
    • Braunlin, W.1    Xu, Q.2    Hook, P.3
  • 34
    • 0034628426 scopus 로고    scopus 로고
    • Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A
    • Kyne L, Warny M, Qamar A, Kelly CP. Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A. N Engl J Med 2000;342:390-7.
    • (2000) N Engl J Med , vol.342 , pp. 390-397
    • Kyne, L.1    Warny, M.2    Qamar, A.3    Kelly, C.P.4
  • 35
    • 0025853417 scopus 로고
    • In vitro and in vivo evaluation of tiacumicins B and C against Clostridium difficile
    • Swanson RN, Hardy DJ, Shipkowitz NL, et al. In vitro and in vivo evaluation of tiacumicins B and C against Clostridium difficile. Antimicrob Agents Chemother 1991;35:1108-11.
    • (1991) Antimicrob Agents Chemother , vol.35 , pp. 1108-1111
    • Swanson, R.N.1    Hardy, D.J.2    Shipkowitz, N.L.3
  • 36
    • 0035145510 scopus 로고    scopus 로고
    • Safety and immunogenicity of increasing doses of a Clostridium difficile toxoid vaccine administered to healthy adults
    • Kouoff K, Wassermann S, Losonsky G, et al. Safety and immunogenicity of increasing doses of a Clostridium difficile toxoid vaccine administered to healthy adults. Infect Immun 2001;69:988-95.
    • (2001) Infect Immun , vol.69 , pp. 988-995
    • Kouoff, K.1    Wassermann, S.2    Losonsky, G.3
  • 37
    • 0035915688 scopus 로고    scopus 로고
    • Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhoea
    • Kyne L, Warny M, Qamar A, et al. Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhoea. Lancet 2001;357:189-93.
    • (2001) Lancet , vol.357 , pp. 189-193
    • Kyne, L.1    Warny, M.2    Qamar, A.3
  • 38
    • 20244383137 scopus 로고    scopus 로고
    • Clostridium difficile toxoid vaccine in recurrent C. difficile-associated diarrhea
    • Sougioultzis S, Kyne L, Drudy D, et al. Clostridium difficile toxoid vaccine in recurrent C. difficile-associated diarrhea. Gastroenterology 2005;128:764-70.
    • (2005) Gastroenterology , vol.128 , pp. 764-770
    • Sougioultzis, S.1    Kyne, L.2    Drudy, D.3
  • 39
    • 0037369921 scopus 로고    scopus 로고
    • Clostridium difficile vaccine and serum immunoglobulin G antibody response to toxin A
    • Aboudola S, Kotloff KL, Kyne L, et al. Clostridium difficile vaccine and serum immunoglobulin G antibody response to toxin A. Infect Immun 2003;71:1608-10.
    • (2003) Infect Immun , vol.71 , pp. 1608-1610
    • Aboudola, S.1    Kotloff, K.L.2    Kyne, L.3
  • 40
    • 33746643774 scopus 로고    scopus 로고
    • New drugs for Clostridium difficile infection
    • Bartlett JG. New drugs for Clostridium difficile infection. Clin Infect Dis 2006;43:428-31.
    • (2006) Clin Infect Dis , vol.43 , pp. 428-431
    • Bartlett, J.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.