Feasibility of using a bone-targeted, macromolecular delivery system coupled with prostaglandin E1 to promote bone formation in aged, estrogen-deficient rats

Pharmaceutical Research

Volumn 25, Issue 12, 2008, Pages 2889-2895

  Miller, S C ^a   Pan, H ^a   Wang, D ^b   Bowman, B M ^a   Kopeckova P ^a   Kopecek J ^a  

^a UNIVERSITY OF UTAH   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Bone formation; HPMA; Macromolecular therapeutics; Prostaglandin; Rats

Indexed keywords

CATHEPSIN K; COPOLYMER; DEXTRO ASPARTIC ACID OCTAPEPTIDE; FLUORESCEIN ISOTHIOCYANATE; N (2 HYDROXYPROPYL)METHACRYLAMIDE; N (2 HYDROXYPROPYL)METHACRYLAMIDE DEXTRO ASPARTIC ACID OCTAPEPTIDE FLUORESCEIN ISOTHIOCYANATE PROSTAGLANDIN E1 CONJUGATE; PROSTAGLANDIN E1; TETRACYCLINE; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG SYNTHESIS; DRUG TARGETING; DRUG UPTAKE; ESTROGEN DEFICIENCY; FEMALE; MACROMOLECULE; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; RAT;

AGING; ALPROSTADIL; ANIMALS; ASPARTIC ACID; DRUG DELIVERY SYSTEMS; ESTROGENS; FEMALE; FLUORESCEIN-5-ISOTHIOCYANATE; METHACRYLATES; OLIGOPEPTIDES; OSTEOGENESIS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 57149144795     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-008-9706-0     Document Type: Conference Paper

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